Acute care surgeons at Vanderbilt University Medical Center are leading a two-year, multicenter observational study of a minimally invasive technique to control life-threatening blood loss by inserting a balloon inside the aorta to restrict blood flow below the heart.
Diabetes control can significantly improve for Latinos when a pharmacist implements an intervention that addresses these patients’ barriers to medication adherence.
A newly published quality improvement study shows how a simple intervention by health care providers reduced the number of older adult patients with type 2 diabetes at risk for hypoglycemia (low blood sugar) by almost 50% and led to de-escalation of diabetes medications that cause hypoglycemia in 20% of patients.
An estimated 80% of older adults in the U.S. have high blood pressure. Maintaining healthy blood pressure can protect against serious conditions like heart failure, heart attacks, and strokes.
BACKGROUNDMesenchymal stem cells (MSCs) have been used in liver transplantation and have certain effects in alleviating liver ischemia-reperfusion injury (IRI) and regulating immune rejection. However, some studies have indicated that the e
Researchers at the Icahn School of Medicine at Mount Sinai have been awarded a $10.2 million grant from the National Heart, Lung and Blood Institute of the National Institutes of Health to investigate risk factors for malignant arrhythmias in mitral valve prolapse.
RUDN University doctors studied what happens to oxidative and antioxidant processes in the heart during diabetes and hypertension. The work provides insight into the relationship between these processes at the molecular level and outlines possible therapeutic targets.
A new Dartmouth study in the journal Science Advances suggests that how well people with diabetes manage their blood sugar depends on their experience with the condition and their overall success in controlling their glucose levels, as well as on the season and time of day.
Mice that consumed caffeine when awake slept more solidly and their overall amount of non-REM and REM sleep was not changed because they “slept in” later.
Scientists at St. Jude Children’s Research Hospital may be able to better predict outcomes and treat patients with the most common childhood cancer by more clearly defining hyperdiploidy.
Women aged 18 to 44 living in states that outlaw Sunday liquor sales or driving with a blood alcohol concentration greater than .08 drink less than their counterparts in other states, according to a new study recently published in Alcohol: Clinical and Experimental Research.
Hypertension affects some 120 million Americans. Training future healthcare professionals how to consistently take accurate blood pressure measurement (BMP) is an important aspect to monitoring patients’ blood pressure.
As we honor lymphoma awareness month, what do you want our patients and families to pause and remember?Lymphoma is a disease which can strike any one of us, young and old, at any time.
NCCN 2023 Annual Congress: Hematologic Malignancies features expert perspectives on developments in blood cancer treatment, including NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) Updates, CAR T-Cell therapy, BTK Inhibitors, Bispecific T-Cell Engagers, and More. The live event is taking place September 22-23, 2023, at the Hilton San Francisco Union Square.
New research has shown that boosting the ‘warm glow’ feeling that people experience after giving blood significantly increases repeat blood donations, which are essential for the effective running of any health service.
For his work discovering the basis for hemoglobin gene switching and applying those insights to develop a therapy for sickle cell disease and other blood diseases, the Institute for Regenerative Medicine at the University of Pennsylvania awarded Stuart Orkin, MD the third Elaine Redding Brinster Prize in Science or Medicine.
In the 25 years since the Nobel Prize was awarded for discovering the role that nitric oxide (NO) plays in the cardiovascular system, researchers have been racing to learn more about how this mysterious signaling molecule works to repair blood vessels damaged by a heart attack, stroke or other cardiovascular event.
Scientists at Johns Hopkins All Children’s Hospital are shedding new light on the causes of Type 2 diabetes and offering a potential strategy for developing new therapies, or perhaps, even prevent Type 2 diabetes from developing.
Analysis of anticoagulants in patients with malignant cancer shows that further study is needed to establish an adjuvant, or combined, treatment protocol.
Over the years, dedicated sickle cell disease programs and research initiatives have greatly improved patient care and life expectancy. But, giving these patients the care they require still presents a number of challenges, including inadequate funding for sickle cell programs, lack of research, and limited access to healthcare.
A ground-breaking study by researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) has revealed crucial insights into the role of the histone methyltransferase NSD2 and its epigenetic target PKCα in causing t(4;14) translocated multiple myeloma (MM), a high-risk subtype of blood cancer, to be more aggressive and resistant to treatment.
The blood-brain barrier (BBB) has been found to play a significant role in controlling behavior critical to how ant colonies function, according to new research from the Perelman School of Medicine at the University of Pennsylvania.
Researchers at the Icahn School of Medicine at Mount Sinai have identified the structure of a special transporter found in red blood cells and how it interacts with drugs.
A research team, affiliated with UNIST has achieved a groundbreaking milestone in tissue regeneration by developing a technology that utilizes autologous blood to produce three-dimensional microvascular implants.
The National Institute of General Medical Sciences has awarded Justin Taylor, M.D., a researcher at Sylvester Comprehensive Cancer Center, a five-year grant totaling $1.92 million for his work to better define the role of XPO1 (Exportin-1) in cancer.
A new study from researchers with Sylvester Comprehensive Cancer Center and other top-tier cancer centers highlights the vital role that the immune system plays in determining the duration of patients’ remission from multiple myeloma.
An analysis of 10 years of health data showed that risk factors for needing mechanical ventilation changed for patients with newly diagnosed sepsis as more time passed after onset.
A broad new strategy could hold hope for treating virtually all blood cancers with CAR T cell therapy, which is currently approved for five subtypes of blood cancer.
Despite advancements in care, a Michigan Medicine study finds that the death rate for pulmonary embolism remains high and unchanged in recent years – more often killing men, Black patients and those from rural areas.
UChicago Medicine Comer Children’s Hospital was one of three sites to enroll patients in a clinical trial to test a potentially curative stem cell gene therapy for sickle cell disease. The results were promising.
The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.
Recent developments include a novel computational tool to detect single base pair DNA changes in single-cell sequencing data, a potential target to treat hypertension caused by drugs commonly used in organ transplants, further insights into the steps involved in genetic recombination, a novel treatment target for a subset of adenoid cystic carcinoma (ACC), a combination therapy that improves outcomes in certain patients with acute myeloid leukemia (AML), and a target for treating prolonged cytopenia in patients with relapsed/refractory large B cell lymphoma treated with chimeric antigen receptor (CAR) T cell therapy.
Playing a Mozart lullaby may help reduce the pain experienced by newborn babies undergoing a heel prick blood test, according to a randomised, blinded clinical trial involving 100 infants published in Pediatric Research.
Professor Ashok Venkitaraman, Director of the Cancer Science Institute of Singapore at the National University of Singapore, together with Assistant Professor Tobias Janowitz, Principal Investigator at the Cold Spring Harbor Laboratory in New York, and an international group of researchers from the USA and UK, have discovered that ketogenic diets delay tumour growth but accelerate cachexia, a wasting syndrome, an unintended side effect that could cause death.
En julio, salió al mercado el primer análisis de sangre directo al consumidor diseñado para evaluar el riesgo de un usuario de desarrollar la enfermedad de Alzheimer.
A study of 14 astronauts suggests that while space travel depletes red blood cells and bone, the body can eventually replenish them back on Earth with the help of fat stored in the bone marrow.
Researchers at Albert Einstein College of Medicine have found that the virus responsible for chikungunya fever can spread directly from cell to cell—perhaps solving the longstanding mystery of how the virus, now emerging as a major health threat, can manage to escape antibodies circulating in the bloodstream.
New research shows blood cancers are often misdiagnosed, an NCI grant to develop a urine test for prostate cancer, a surgeon-scientist receives Sylvester’s first DoD grant to study pancreatic cancer, bolstering emergency preparedness for climate-driven disasters, and more are included in this month’s tip sheet .
Patients with the genetic disorder hemophilia A receive factor VIII protein replacement treatments to replenish this clotting protein in their blood, thus preventing dangerous bleeding. Unfortunately, about 30 percent of these patients develop antibodies against the treatment and until now, despite more than 80 years of clinical experience with this complication, little has been known about its mechanism.
The new observation, made by UNC School of Medicine’s Stephan Moll, MD, and Jacquelyn Baskin-Miller, MD, suggests that a life-threatening blood clotting disorder can be caused by an infection with adenovirus, one of the most common respiratory viruses in pediatric and adult patients.
Innovative technology that creates ultra-thin layers of human cells in tube-like structures could spur development of lifelike blood vessels and intestines in the lab.
Blood disorders known as myelodysplastic syndromes/neoplasms are commonly misdiagnosed – putting patients at increased risk for treatment mistakes and other potentially harmful consequences. A new study highlights the vital need for strong coordination between clinicians and skilled pathologists to ensure accurate, timely diagnosis of blood cancers.