New antibiotic resistance genes identified in tuberculosis
PLOSAn international consortium analyzed the genetic sequences and antibiotic susceptibility of more than 10,000 global Mycobacterium tuberculosis isolates.
An international consortium analyzed the genetic sequences and antibiotic susceptibility of more than 10,000 global Mycobacterium tuberculosis isolates.
Urinary tract infections are common, yet can be tough to treat as the bacteria that cause them become resistant to many antibiotics. In ACS Central Science, researchers report a new molecule that inhibits drug-resistant bacteria in lab experiments, as well as in mice with pneumonia and UTIs.
An international research team has deciphered the mechanism by which the fungus Cryptococcus neoformans is resistant to fungus-specific drugs.
Scientists are using new technologies to obtain unprecedented looks inside viruses and their unique abilities to infect and destroy bacteria. Using cryo-EM and other technologies, they found that jumbo phage cells feature a compartment that is surprisingly similar to the nucleus of human cells.
Here are some of the latest articles that have been added to the Drug Resistance channel on Newswise, a free source for journalists.
Researchers at Canada's McMaster University have discovered a significant and previously unknown mechanism that many bacteria use to resist antibiotics.
Patients with relapsed multiple myeloma are resistant to commonly used treatments. Researchers are one step closer to understanding the genetic reason why.
Patients who have indwelling urinary catheters often suffer from urinary tract infections, which can be difficult to treat.
New research, led by a team a the University of Bristol, has revealed an association between the feeding of raw meat to pet dogs and the presence of bacteria resistant to critically important antibiotics.
The latest research news in Climate Science on Newswise.
Scientists have uncovered an intriguing new understanding of how viruses and the hosts they infect evolve new innovations to outcompete each other. Culminating a 10-year research effort, the researchers tracked the way fitness landscapes constantly change in the ongoing struggle for survival.
Silents are potentially golden in the search for antibiotics to slow the ongoing crisis of resistance in the treatment of disease.
UC San Diego researchers say they may have found the reason why multiple human clinical trials of staphylococcus vaccines have failed: the bacteria knows us too well.
Lactobacilli that live in the human female urinary tract’s microbiome are competitive and kill nearby pathogenic bacteria, says the first study of its kind done at The University of Alabama in Huntsville (UAH). Greater understanding of the processes involved could lead to new therapies.
Experts Encourage Rapid Genomic Screenings and Development of New Therapeutics for Drug-Resistant Pathogens to Address Emerging Global Health Concern
A new study reveals why a highly infectious variant of the cholera bug, which caused large disease outbreaks in the early 1990s, did not cause the eighth cholera pandemic as feared – but instead unexpectedly disappeared.
New Cleveland Clinic research has uncovered key information about cellular interaction between tumor cells and normal tissue, providing better understanding of how therapeutic resistance develops. Findings published in Science Advances.
A new study has found that a highly antibiotic-resistant strain of the superbug MRSA – methicillin resistant Staphylococcus aureus – has emerged in livestock in the last 50 years, probably due to widespread antibiotic use in pig farming.
Researchers at McMaster University have unlocked an evolutionary mystery of a deadly pathogen responsible for fueling the superbug crisis: it can reproduce by having sex.
Chula Veterinary Lecturer and “National Outstanding Researcher 2022” has revealed the genetic code that causes drug resistance in animals that affects human health, animals, and the environment, and suggests comprehensive solutions under the concept “One Health”.
Understanding why and how chemotherapy resistance occurs is a major step toward optimizing treatments for cancer. A team of scientists including Markus Seeliger, PhD, of the Renaissance School of Medicine at Stony Brook University, believe they have found a new process through which drug resistance happens.
In a new article published in Science Translational Medicine, Moffitt Cancer Center researchers reveal a mechanism by which prostate cancer cells become resistant through molecular modification of the androgen receptor protein and identify a potential treatment approach that could overcome this resistance.
Scientists have demonstrated how some fast-growing bacteria can retreatment with antibiotics, according to a study published today in eLife.
A study published today in Cell Reports reveals how populations of a bacterium called Pseudomonas respond to being treated with Colistin, a 'last resort' antibiotic for patients who have developed multi-drug resistant infections.
An estimated 70 percent of primary care physicians reported in a survey that they would still prescribe antibiotics to treat asymptomatic infections based solely on a positive urine specimen.
Using neutrons, researchers at Oak Ridge National Laboratory pieced together the molecular mechanics behind a peptide’s ability to deal significant damage to bacterial cells. Their findings could inform new therapeutic strategies for treating bacterial infections where antibiotics have fallen short.
Old dogs may not learn new tricks, but old drugs can, according to a research team based in China.
A new study from The University of Toledo College of Medicine and Life Sciences has shown gut bacteria can reduce the effectiveness of certain blood pressure drugs.
Children who were prescribed antibiotics inappropriately were more likely to develop complications such as diarrhea and skin rashes than children who were treated according to medical guidelines, according to a new study from Washington University School of Medicine in St. Louis and The Pew Charitable Trusts. This misuse of antibiotics resulted in at least $74 million in excess health-care costs in the U.S. in 2017.
A Johns Hopkins Children’s Center-led national quality improvement collaborative highlights a “less is more” method that may prevent antibiotic overprescribing
Biologists have discovered an aberrant protein that’s deadly to bacteria. The discovery could help scientists unravel the lethal mechanism of certain antibiotics—and potentially point the way to future antibacterial drugs.
Researchers at UC San Diego have used a systems biology approach to parse the genetic diversity of Clostridioides difficile, a particularly problematic pathogen, particularly in health care settings.
Antibiotics have once proclaimed the salvation of the world. Today, researchers fear that antibiotics could become a threat to public health and the natural environment.
Among those hospitalised during the pandemic, both COVID-19 patients and those tested for SARS-COV-2 but negative, had higher rates of antibiotic-resistant bacterial infections compared to patients hospitalised before the pandemic, according to a study evaluating the pandemic’s impact on antimicrobial resistance (AMR) in 271 hospitals across the USA, to be presented at this year’s European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Lisbon, Portugal (23-26 April).
Experts from the University of Nottingham have developed a ground-breaking software, which combines DNA sequencing and machine learning to help them find where, and to what extent, antibiotic resistant bacteria is being transmitted between humans, animals and the environment.
Over the past few decades, obesity has become increasingly common throughout the entire world.
A recent study published in the journal Communications Biology shows manipulating and deleting a specific gene (AMN1) from yeast could provide a foundation for a new approach to combatting drug resistance when treating microbial infections or cancer.
University of Maryland School of Medicine (UMSOM)’s Institute of Human Virology (IHV) researchers received funding from the National Institutes of Health’s National Institute of Allergy and Infectious Diseases (NIAID) for $2.7 million to study genetic changes in two genes from the HIV-1 virus that may make it resistant to antiretroviral therapy.
Demand for new kinds of antibiotics is surging, as drug-resistant and emerging infections are becoming an increasingly serious global health threat. Researchers are racing to reexamine certain microbes that serve as one of our most successful sources of therapeutics: the actinomycetes.
Dr. Oladele "Dele" Ogunseitan, UC Presidential Chair and Professor of Population Health and Disease Prevention at the University of California, Irvine Program in Public Health, discusses using a One Health approach to combating global antibiotic resistance.
Most antibiotics are double-edged swords. Besides killing the pathogen they are prescribed for, they also decimate beneficial bacteria and change the composition of the gut microbiome.
Here are some of the latest articles that have been added to the Clinical Trials channel on Newswise.
有越来越多人因抗生素耐药性感染而面临死亡。此类感染是微生物物种通过突变以躲避制药破坏性攻击所引发的。仅2019年,全球便有超过120万人死于抗生素耐药性感染。
مدينة روتشستر، ولاية مينيسوتا- يموت عدد متزايد من الناس بسبب العَدوى المقاومة للمضادات الحيوية. وهذه العَدوى تغذيها أنواع الميكروبات التي تتحور لتتجنب الأدوية المطورة بهدف تدميرها. توفي أكثر من 1.2 مليون شخص حول العالم في عام 2019 بسبب العَدوى المقاومة للمضادات الحيوية.
Cada vez mais pessoas estão morrendo por infecções resistentes a antibióticos. Essas infecções são alimentadas por espécies microbianas que estão em mutação para escapar das drogas desenvolvidas para destruí-las.
Una creciente cantidad de personas muere debido a infecciones resistentes a los antibióticos. Estas infecciones son propiciadas por especies bacterianas que mutan a fin de evadir a los fármacos creados para destruirlas.
If you’ve been hitting the gym and getting results, you know it’s time to strut your stuff; and it turns out bacteria feel the same way.
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