Feature Channels: Drug Resistance

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Newswise: Hospital-affiliated doctors prescribe fewer antibiotics through telehealth than third-party physicians
Released: 8-Mar-2022 10:05 AM EST
Hospital-affiliated doctors prescribe fewer antibiotics through telehealth than third-party physicians
Michigan Medicine - University of Michigan

A new study found that for telemedicine visits related to acute respiratory infection, contractor-supplied physicians prescribed antibiotics to patients nearly twice as often as emergency physicians employed by the hospital system. As the majority of acute respiratory infections are viral, researchers say the findings highlight concerns of antibiotic stewardship amid growing antibiotic resistance.

Released: 1-Mar-2022 4:45 PM EST
Genome Refolding Contributes to Cancer Therapy Resistance, Penn Study Finds
Perelman School of Medicine at the University of Pennsylvania

While gene mutations can lead to drug resistance, researchers in the Perelman School of Medicine at the University of Pennsylvania have identified an important, non-genetic adaptation that could also drive resistance to targeted therapy in T cell leukemia, a type of blood cell cancer.

Released: 1-Mar-2022 10:10 AM EST
Fungal infections cost U.S. $6.7B in a year
University of Georgia

New research from the University of Georgia found that fungal infections account for $6.7 billion in health care spending in 2018. And that’s just the cases that were directly responsible for inpatient hospital stays.

Newswise: The protective armour of superbug C.difficile revealed
Released: 25-Feb-2022 1:45 PM EST
The protective armour of superbug C.difficile revealed
Newcastle University

The spectacular structure of the protective armour of superbug C.difficile has been revealed for the first time showing the close-knit yet flexible outer layer – like chain mail.

Released: 24-Feb-2022 3:05 PM EST
Machine Learning Antibiotic Prescriptions Can Help Minimize Resistance Spread
American Technion Society

Using genomic sequencing techniques and machine learning analysis of patient records, Israeli researchers have developed an antibiotic prescribing algorithm that cuts the risk of emergence of antibiotic resistance by half.

17-Feb-2022 3:35 PM EST
The Latest Research News in Cardiovascular Health
Newswise

The Latest Research News in Cardiovascular Health

Newswise: Protein structure offers clues to drug-resistance mechanism
Released: 18-Feb-2022 12:50 PM EST
Protein structure offers clues to drug-resistance mechanism
Massachusetts Institute of Technology (MIT)

MIT chemists have discovered the structure of a protein that can pump toxic molecules out of bacterial cells. Proteins similar to this one, which is found in E. coli, are believed to help bacteria become resistant to multiple antibiotics.

Newswise: Elsa U. Pardee Foundation and National Cancer Institute Fund Leukemia Research at TTUHSC El Paso
Released: 17-Feb-2022 12:00 PM EST
Elsa U. Pardee Foundation and National Cancer Institute Fund Leukemia Research at TTUHSC El Paso
Texas Tech University Health Sciences Center El Paso

Texas Tech University Health Sciences Center El Paso has received more than a quarter-million dollars to study the proteins that contribute to disease progression and drug resistance in acute myeloid leukemia.

Newswise: New UNC Charlotte research center to drive pandemic preparedness and prevention
Released: 9-Feb-2022 1:50 PM EST
New UNC Charlotte research center to drive pandemic preparedness and prevention
University of North Carolina at Charlotte

The key to preventing another global pandemic may be found at UNC Charlotte. Expanding upon the University’s award-winning development of a novel COVID-19 wastewater surveillance program and rapidly growing success in bioinformatics, the University is bringing together experts to explore ways to combat threats to human health.

   
Released: 8-Feb-2022 12:20 PM EST
Agricultural fungicides may be driving antimicrobial resistance
University of Georgia

New research from the University of Georgia has shown, for the first time, that compounds used to fight fungal diseases in plants are causing resistance to antifungal medications used to treat people.

Newswise: Ludwig Cancer Research Study Identifies Potential Vulnerability in Drug-Resistant Neuroblastoma
Released: 7-Feb-2022 12:45 PM EST
Ludwig Cancer Research Study Identifies Potential Vulnerability in Drug-Resistant Neuroblastoma
Ludwig Cancer Research

A Ludwig Cancer Research study has identified a potential vulnerability in neuroblastoma tumors that might be exploited to improve treatment of the aggressive childhood cancer, which accounts for roughly 15% of all deaths from pediatric malignancies.

Released: 4-Feb-2022 11:20 AM EST
Shorter Treatment is Better for Young Children with Outpatient Pneumonia
Vanderbilt University Medical Center

Five days of antibiotics is superior to 10 days for children with community-acquired pneumonia who are not hospitalized, according to a study published in JAMA Pediatrics.

Released: 26-Jan-2022 1:45 PM EST
The latest news in Behavioral Science for media
Newswise

Here are some of the latest articles we've posted in the Behavioral Science channel.

       
Released: 24-Jan-2022 3:40 PM EST
The Latest Research News from the Health Disparities Channel
Newswise

The latest research news from the Health Disparities Channel.

Released: 20-Jan-2022 3:45 PM EST
What Is Combination Drug Therapy?
Tufts University

Using drugs in synergistic combinations may clear infections more efficiently and slow the acquisition of drug resistance. Bree Aldridge of Tufts University School of Medicine explains how researchers find the right drug cocktails, slowing AMR, and the role artificial intelligence can have in both.

   
Newswise: New Tool Assesses Evolutionary Risks of Antibiotics
Released: 19-Jan-2022 1:30 PM EST
New Tool Assesses Evolutionary Risks of Antibiotics
University of California San Diego

Countering a rising antibiotic resistance crisis, doctors now prescribe combinations of antibiotics. Yet many risks are involved with such multi-drug combinations. Scientists have developed a way to help doctors evaluate outcomes for different drug pairs and boost the odds of successful treatment.

Newswise: Scientists prove that deadly gene has jumped from a harmless organism to a nasty pathogen
Released: 17-Jan-2022 5:05 PM EST
Scientists prove that deadly gene has jumped from a harmless organism to a nasty pathogen
University of South Australia

Australian scientists have made a surprising discovery in the origins of an antibiotic-resistant gene previously thought to have been confined to Adelaide.

Newswise: Sanford Burnham Prebys researchers awarded $3.6 million to study antibiotic resistance
Released: 13-Jan-2022 5:35 PM EST
Sanford Burnham Prebys researchers awarded $3.6 million to study antibiotic resistance
Sanford Burnham Prebys

Sanford Burnham Prebys professor Andrei Osterman, Ph.D., has been awarded a $3.6 million grant from the National Institutes of Health (NIH) to expand current knowledge of antibiotic resistance, which will inform more precise antibiotic prescribing practices and help researchers develop drugs that are harder for bacteria to resist.

Newswise: Unlocking the secrets of a critical schistosomiasis drug
Released: 6-Jan-2022 12:00 PM EST
Unlocking the secrets of a critical schistosomiasis drug
Texas Biomedical Research Institute

For decades, no one really knew how the drug praziquantel treated a parasitic disease afflicting more than 200 million people around the world. Now, two independent teams of researchers have found the answer, which could help lead to improved treatments that support the W.H.O.’s goal of eliminating Schistosomiasis as a public health problem by 2025.

Newswise: Plasma-Based Engineering Creates Contact-Killing, Antifouling, Drug-Release Surfaces
Released: 4-Jan-2022 10:05 AM EST
Plasma-Based Engineering Creates Contact-Killing, Antifouling, Drug-Release Surfaces
American Institute of Physics (AIP)

Conventional wet-chemistry methods used to create biocidal materials are complex, time-consuming, and expensive. In the Journal of Applied Physics, researchers present a tutorial in which they explore a promising alternative called plasma-enabled surface engineering. The technology relies on nonequilibrium plasma that produces chemical reactions to change the properties at the material surface. Reactions can be manipulated by adjusting electric power for surface activation, coating deposition, and surface nanostructuring of virtually any solid material.

Released: 28-Dec-2021 1:40 PM EST
CDC Awards $2 Million to Penn to Combat Antimicrobial Resistance in Southern Africa
Perelman School of Medicine at the University of Pennsylvania

More than $2 million in grants from the U.S. Centers for Disease Control and Prevention (CDC) will allow a Penn Medicine team to further develop infrastructure and clinical capacity to address antimicrobial resistance and infectious diseases in Botswana.

Newswise: UCLA Jonsson Comprehensive Cancer Center study details chromosome-level changes that allow melanomas to develop drug resistance
Released: 20-Dec-2021 2:55 PM EST
UCLA Jonsson Comprehensive Cancer Center study details chromosome-level changes that allow melanomas to develop drug resistance
University of California, Los Angeles (UCLA), Health Sciences

UCLA Jonsson Comprehensive Cancer Center researchers led the development of a melanoma model of drug resistance, enabling them to study structures and dynamics resulting in intrachromosomal and extrachromosomal changes that support resistance in cancer cells.

Newswise: Pet Scans Help Guide Drug to Best Treat Orthopaedic Implant Bacterial Infections
Released: 16-Dec-2021 11:20 AM EST
Pet Scans Help Guide Drug to Best Treat Orthopaedic Implant Bacterial Infections
Johns Hopkins Medicine

Treating bacterial infections associated with orthopaedic implants has often been a case of too little, too late. The traditional therapy has been a combination of prolonged antibiotics, including rifampin, a 50-year-old drug that has been a staple in the global fight against tuberculosis and other bacterial diseases.

Released: 15-Dec-2021 4:10 PM EST
Researchers first to predict when bacteria may become resistant to antibiotics
University College London

Scientists have spotted signs of ‘pre-resistance’ in bacteria for the first time – signs that particular bacteria are likely to become resistant to antibiotics in the future – in a new study led by UCL and Great Ormond Street Hospital researchers.

Released: 13-Dec-2021 4:40 PM EST
New resistance-busting antibiotic combination could extend the use of ‘last-resort’ antibiotics
University of Oxford

Scientists have discovered a new potential treatment that has the ability to reverse antibiotic resistance in bacteria that cause conditions such as sepsis, pneumonia, and urinary tract infections.

   
Released: 30-Nov-2021 3:20 PM EST
Ohio State takes 'One Health' approach to identify antibiotic-resistant bacteria
Ohio State University Wexner Medical Center

With the knowledge that human, animal and environmental health are intertwined, researchers at five of The Ohio State University’s colleges and its medical center are uniquely positioned to collaborate on a “one health” approach to battle antibiotic resistance and prevent the next global health crisis.

Released: 30-Nov-2021 1:35 PM EST
Single-cell sequencing and bioinformatic tools applications discussed in Research Review
Sbarro Health Research Organization (SHRO)

Nowadays, single-cell RNA sequencing technologies and related bioinformatics tools are emerging as essential devices for dissecting tumors at single-cell resolution and understanding carcinogenesis and drug response mechanisms, representing a turning point in cancer research.

Released: 23-Nov-2021 1:25 PM EST
Ultrashort-pulse lasers kill bacterial superbugs, spores
Washington University in St. Louis

Researchers at Washington University School of Medicine in St. Louis have found that multidrug-resistant bacteria and bacterial spores can be killed by ultrashort-pulse lasers. The findings could lead to new ways to sterilize wounds and blood products without damaging human cells.

Released: 17-Nov-2021 10:10 AM EST
New group of antibacterial molecules identified
Karolinska Institute

Researchers at Karolinska Institutet, Umeå University, and the University of Bonn have identified a new group of molecules that have an antibacterial effect against many antibiotic-resistant bacteria.

12-Nov-2021 11:30 AM EST
New approach could overcome fungal resistance to current treatments
American Chemical Society (ACS)

Researchers report in ACS Infectious Diseases that they have identified compounds that tackle fungal resistance in a new way — by interfering with fungal enzymes required for fatty acid synthesis — potentially opening the door to better therapies.

Released: 11-Nov-2021 8:15 AM EST
‘Wonder gas’ hailed as new treatment for diabetic foot ulcers could also kill COVID-19 virus indoors
University of South Australia

In an experiment to find an effective treatment for diabetic foot ulcers, which affect 62 million people worldwide, a team led by University of South Australia physicist Dr Endre Szili has made an unexpected discovery: the same technology kills the SARS-CoV-2 virus.

   
1-Nov-2021 8:00 AM EDT
Pregnant Women with Penicillin Allergy Label Should be Tested to Reduce Antibiotic Exposure
American College of Allergy, Asthma and Immunology (ACAAI)

A new study being presented at this year’s ACAAI Annual Scientific Meeting showed the majority of pregnant women with a penicillin allergy label who were tested were not allergic and could tolerate penicillin during labor.

1-Nov-2021 8:00 AM EDT
Las mujeres embarazadas con etiqueta de alergia a la penicilina deberían evaluar su alergia para reducir la exposición a antibióticos
American College of Allergy, Asthma and Immunology (ACAAI)

Un nuevo estudio que se presenta en la Reunión científica anual del ACAAI de este año mostró que la mayoría de las mujeres embarazadas con una etiqueta de alergia a la penicilina a las que se les hizo la prueba no eran alérgicas y podían tolerar la penicilina durante el parto.

Released: 3-Nov-2021 5:05 PM EDT
Test determines antibiotic resistance in less than 90 minutes
Washington State University

A technique that measures the metabolic activity of bacteria with an electric probe can identify antibiotic resistance in less than 90 minutes, a dramatic improvement from the one to two days required by current techniques.

Newswise: Combating Antibiotic Resistance
Released: 3-Nov-2021 2:55 PM EDT
Combating Antibiotic Resistance
Harvard Medical School

As bacterial infections impervious to drugs rise, so does the need to develop better antibiotics

Released: 2-Nov-2021 8:40 AM EDT
Antibiotic resistance outwitted by supercomputers
University of Portsmouth

Scientists may have made a giant leap in fighting the biggest threat to human health by using supercomputing to keep pace with the impressive ability of diseases to evolve. A new study by an international team, co-led by Dr Gerhard Koenig from the University of Portsmouth, tackled the problem of antibiotic resistance by redesigning existing antibiotics to overcome bacterial resistance mechanisms.

Released: 28-Oct-2021 2:45 PM EDT
New ribosome-targeting antibiotic acts against drug-resistant bacteria
University of Illinois Chicago

A new study published in Nature reports on the molecular mechanism that allows a new antibiotic drug to overcome resistance.

Newswise: Yale Cancer Center Study Shows New Strategy to Fight Drug Resistance in HER2-Positive Breast and Ovarian Cancers
26-Oct-2021 11:20 AM EDT
Yale Cancer Center Study Shows New Strategy to Fight Drug Resistance in HER2-Positive Breast and Ovarian Cancers
Yale Cancer Center/Smilow Cancer Hospital

New findings by researchers at Yale Cancer Center demonstrate a novel strategy to treat tumor growth in breast and ovarian cancers characterized by HER2 gene amplification, an increase in the number of copies of a gene.

Released: 22-Oct-2021 2:30 PM EDT
Machine learning predicts antibiotic resistance spread
Cornell University

Genes aren’t only inherited through birth. Bacteria have the ability to pass genes to each other, or pick them up from their environment, through a process called horizonal gene transfer, which is a major culprit in the spread of antibiotic resistance.

Released: 12-Oct-2021 12:55 PM EDT
Researcher discovers key gene responsible for cancer drug resistance
University of Missouri, Columbia

A researcher at the University of Missouri School of Medicine has discovered an enzyme that plays a key role in the ability of cancer cells to resist drug treatment.

Released: 6-Oct-2021 3:45 PM EDT
‘Living medicine’ created to treat drug-resistant infections
Center for Genomic Regulation

Researchers at the Centre for Genomic Regulation (CRG) and Pulmobiotics S.L have created the first ‘living medicine’ to treat antibiotic-resistant bacteria growing on the surfaces of medical implants.

Newswise:Video Embedded what-you-need-to-know-about-urinary-tract-infections
VIDEO
Released: 29-Sep-2021 10:25 AM EDT
What You Need to Know About Urinary Tract Infections
Cedars-Sinai

More than half of U.S. women will experience at least one urinary tract infection (UTI) in their lifetimes, while a quarter will have a subsequent infection. Recurrent urinary tract infections are defined as two or more infections in six months or three or more in a year.

Released: 22-Sep-2021 9:45 AM EDT
Dog parasite is developing resistance to treatments
University of Georgia

Right now, U.S. veterinarians rely on three types of drugs to kill the hookworms, but the parasites appear to becoming resistant to all of them.

Newswise: Study Unravels the Structure of Bacterial P Pili
Released: 22-Sep-2021 9:30 AM EDT
Study Unravels the Structure of Bacterial P Pili
Stony Brook University

A research team led by Stony Brook University has used molecular biology and cryoelectron microscopy to successfully unravel the structure of bacterial appendages called P pili. The finding, published in Nature Communications, is a key step in order to target P pili in the infection process.

Released: 16-Sep-2021 11:55 AM EDT
Researchers explore promising treatment for MRSA ‘superbug’
Cornell University

A new Cornell study has found the antimicrobial properties of certain stem cell proteins could offer a potential treatment to reduce infection in skin wounds.

   
Released: 8-Sep-2021 5:05 AM EDT
Human antibiotic use affects wild bears
Norwegian University of Science and Technology (NTNU)

Bears that are killed often end up in museum collections. New technology allows us to see how the genes in these bears have changed over the years, and the same applies to their bacteria.

Released: 30-Aug-2021 4:20 PM EDT
Closing the gate on manganese could open doors to new drugs to treat pneumonia
SLAC National Accelerator Laboratory

Drawing on SLAC facilities, Australian researchers have revealed how Streptococcus pneumoniae bacteria obtain manganese from our bodies, which could lead to better therapies to target the pathogen.

Released: 26-Aug-2021 1:10 PM EDT
History of human antibiotic use written in the oral bacteria of wild brown bears
Uppsala University

An international team of researchers used historical museum collections to study the effects of human-made antibiotics over the entire history of their application.

Released: 19-Aug-2021 3:00 PM EDT
VIDEO AND TRANSCRIPT AVAILABLE: Breakthrough Cases and COVID Boosters: Live Expert Panel for August 18, 2021
Newswise

Expert Q&A: Do breakthrough cases mean we will soon need COVID boosters? The extremely contagious Delta variant continues to spread, prompting mask mandates, proof of vaccination, and other measures. Media invited to ask the experts about these and related topics.

Released: 17-Aug-2021 8:50 AM EDT
First-of-its-kind Asian Clinical Research Network established to tackle drug-resistant infections in the region
National University of Singapore (NUS)

Wellcome Trust has provided a grant to the National University of Singapore to establish the Asian Clinical Research Network to conduct antimicrobial clinical research to develop the most effective ways to treat and prevent life-threatening drug-resistant infections. This will be the first clinical trial network established in Asia focusing on drug-resistant infections.



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