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Medicine

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PFAS, Nuclear Medicine, perfluorinated alkyl substances, Radiolabeling, Chemicals, Health

Researchers Track Perfluorinated Chemicals in the Body

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Scientists have developed a method to track perfluorinated alkyl substances (PFAS) in the body. PFAS are potentially toxic chemicals found in stain-resistant products, nonstick cookware, fire-fighting foams and, most recently, fast food wrappers.

Medicine

Science

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Genomics, Fertilization process, Molecular Biology, zygote

Unique Genome Architectures After Fertilisation in Single-Cell Embryos

Using a newly developed method researchers at the Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA) have been able to shed light on the complexity of genome reorganization occurring during the first hours after fertilization in the single-cell mammalian embryo. Their findings have recently been published in the journal Nature. The team of researchers (from three continents) have discovered that the egg and sperm genomes that co-exist in the single-cell embryo or zygote have a unique structure compared to other interphase cells. Understanding this specialized chromatin “ground state” has the potential to provide insights into the yet mysterious process of epigenetic reprogramming to totipotency, the ability to give rise to all cell types.

Science

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Open Access, Open Access Journal, Free Access To Scientific Literature, free article access, Free Access, Free the Science, scholarly publishing, scholarly journals, scholarly research, scholarly publishers, open science, Free the Science Week, ECS Digital Library, Journal of The Electrochemical Society

Taking Down the Paywall for Free the Science Week

The Electrochemical Society (ECS) is celebrating its 115th anniversary this year by giving the world a preview of what complete open access to peer-reviewed scientific research will look like. ECS will launch the first Free the Science Week, April 3-9, and take down the paywall to the entire ECS Digital Library, making over 132,000 scientific articles and abstracts free and accessible to everyone.

Medicine

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Paralysis, quadriplegia, Case Western Reserve University, Biotechnology, Cleveland FES Center, Biomedical Engineering

Man with Quadriplegia Employs Injury Bridging Technologies to Move Again—Just by Thinking

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Bill Kochevar, who was paralyzed below his shoulders in a bicycling accident, is believed to be the first person with quadriplegia in the world to have arm and hand movements restored with the help of two temporarily implanted technologies.

Medicine

Science

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Collagen, Blood Vessels, tissue implant, replantation, Linker, Tissue Engineering, microsuture, Microsurgery, Vascular Grafts

Tiny Bioengineered Blood Vessel Grafts Aid Delicate Microsurgeries

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Scientists have been working diligently to create engineered tissue implants to repair or replace damaged or diseased tissue and organs; but their success hinges on the ability to build a sturdy connection linking the implant’s blood vessels and the patient’s existing vasculature. National Institute of Biomedical Imaging and Bioengineering (NIBIB)-funded researchers have created segments of engineered blood vessels to address this critical issue.

Science

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Aquarium, Shedd, Microbiome, virome, Viruses, Microbial Communities, aquatic communities, Marine animals, MSU, Michigan State University

MSU, Shedd Aquarium Partnering to Create Healthier Aquatic Homes

Viruses are the most abundant living organisms on the planet, yet we know very little about them, especially in aquatic environments. Michigan State University’s Joan Rose is partnering with Shedd Aquarium in Chicago to better understand how viruses affect plants, fish and aquatic mammals in human-built and controlled aquariums.

Medicine

Science

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Michigan Tech, Chemistry, Cancer, fluorescence imaging, Molecular Biology, Biochemistry and Cell Biology

Fluorescent Probe Could Light Up Cancer

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A fluorescent probe developed by Michigan Tech chemist Haiying Liu lights up the enzyme beta-galactosidase in a cell culture. The glowing probe-enzyme combination could make tumors fluoresce, allowing surgeons to cut away cancer while leaving healthy tissue intact.

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Penn State Biomechanics and Imaging Lab: Elastography

The Biomechanics and Imaging Laboratory aims to develop non-invasive techniques to diagnose and evaluate treatment strategies for degenerative disease and injuries in orthopaedic tissues. To this end, researchers are combining imaging techniques, biomechanics, and modeling to create tools that help clinicians in getting a more accurate diagnosis, evaluating the effectiveness of treatments, and understanding the causes and consequences of injuries and diseases in orthopedic tissues.

Science

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Pancreatic Cancer, lab resear, Cancer, Cancer Research, Cancer Biology, prmt1

Protein Identified as Potential Druggable Target for Pancreatic Cancer

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A protein known as arginine methyltransferase 1 (PRMT1) may be a potential therapeutic target for pancreatic ductal adenocarcinoma (PDAC), the most common type of pancreatic cancer, and one of the most deadliest with a less than 10 percent, five-year survival rate. PRMT1 is involved in a number of genetic processes including gene transcription, DNA repair and signaling.

Science

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Cryo Electron Microscope, Cryo Electron Microscopy, C

Van Andel Research Institute Installs World-Class Microscopes to Enable Discovery of the Molecular Basis of Disease

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Van Andel Research Institute (VARI) is now home to one of the world’s most powerful microscopes—one that images life’s building blocks in startling clarity and equips VARI’s growing team of scientists to push the limits of discovery in search of new treatments for diseases such as cancer and Parkinson’s.







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