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Personalized Medicine

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Science

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Cancer, Genetics, Precision Medicine, personalized medicine, Oral Cancer, Drug Discovery

First Precision Medicine Trial in Cancer Prevention Identifies Molecular-based Chemoprevention Strategy

A team of scientists, led by researchers at University of California, San Diego Moores Cancer Center and The University of Texas MD Anderson Cancer Center, report that a genetic biomarker called loss of heterozygosity or LOH is able to predict which patients with premalignant mouth lesions are at highest risk of developing oral cancer. The findings, published in the November 5, 2015 online issue of Journal of the American Medical Association Oncology, present a new tool that could be used to identify patients most likely to benefit from chemoprevention — and may be applicable to preventing other types of cancer.

Medicine

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neurologic disease, Neurology, Precision Medicine, Genetics

Toddler’s Rare Disease Identified and Treated Using Precision Medicine

A 20-month-old girl suffering from a rare neurodegenerative disease was diagnosed by exome sequencing and successfully treated. The case, which exemplifies the potential of precision medicine, involved scientists at Columbia University Medical Center (CUMC) and Duke University.

Medicine

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Colon And Rectal, Colorectal Cancer, Cancer, Colon Cancer, Metastatic Colon Cancer, Metastatic Colorectal Cancer, Biomarker, Precision Medicine, personalized medicine, Baylor University Medical Center at Dallas, Baylor Research Institute, RNA molecule, Ajay Goel, microRNA biomarker

Newly Identified ‘Biomarker’ May Help Doctors Predict Colon Cancer Progression and Personalize Therapy

Researchers at Baylor Research Institute have identified a small RNA molecule that appears to enable certain colorectal cancers to become especially aggressive, resistant to treatment and likely to migrate and invade normal tissue. Findings suggest that detecting high levels of the molecule could serve as a “biomarker” to help clinicians determine which patients might benefit from more aggressive therapy.

Medicine

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Genomics, Gianrico Farrugia, medical genomics, Precision Medicine, Research

Five Ways Individualized Medicine is Impacting Health Care

How is individualized medicine working? Let us count the ways.

Science

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A Thin Ribbon of Flexible Electronics Can Monitor Health, Infrastructure

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A new world of flexible, bendable, even stretchable electronics is emerging from research labs to address a wide range of potentially game-changing uses. Over the last few years, one team of chemists and materials scientists has begun exploring military applications in harsh environments for aircraft, explosive devices and even combatants themselves. They will present their research at the 250th National Meeting & Exposition of the American Chemical Society.

Medicine

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Adrenal, Primary Aldosteronism, High Blood Pressure, Hypertension, Precision Medicine, Aldosterone

Adrenals Run Amok: Discovery Could Aid Precision Medicine for High Blood Pressure

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Each of your kidneys wears a little yellow cap that helps keep blood pressure in check, and much more. But in some people, it starts running amok, pumping out a hormone that sends blood pressure sky-high. Why this happens is still a mystery. But new findings could help figure out what's going on.

Medicine

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Epigenomics, Personalized Medicine

New Technology Developed by Virginia Tech and the University of Iowa Helps Personalized Medicine by Enabling Epigenomic Analysis with a Mere 100 Cells

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A new technology, improving the efficiency of the studies in epigenomics, is the subject of a Nature Methods journal article by Chang Lu and Zhenning Cao of Virginia Tech and Kai Tan, Changya Chen and Bing He of the University of Iowa. The research was funded by the National Institutes of Health, following a seed grant from Virginia Tech’s Institute for Critical Technology and Applied Science.

Medicine

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Cervical, Dissatisfaction, Lumbar, Patient Satisfaction, Predictors, Spine Surgery

Patient Satisfaction Is Good Indicator of Success after Spinal Surgery

Patient satisfaction ratings after surgery for spinal degenerative disease—especially in terms of reduced pain and disability—are a good indicator of the procedure's effectiveness, reports a study in the August issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Wolters Kluwer.

Medicine

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Prostate Cancer, Cancer, Urology

For Prostate Cancer Patients, Risk-Specific Therapies Now More the Norm

After decades of overtreatment for low-risk prostate cancer and inadequate management of its more aggressive forms, patients are now more likely to receive medical care matched to level of risk, according to a study by researchers at UC San Francisco.

Medicine

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Supercharging Stem Cells to Create New Therapies

Researchers at the University of Adelaide have discovered a new method for culturing stem cells which sees the highly therapeutic cells grow faster and stronger.

Medicine

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Genetic Variation Determines Protein’s Response to Anti-Diabetic Drug

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In the first study of its kind, researchers have shown how an anti-diabetic drug can have variable effects depending on small natural differences in DNA sequence between individuals. They aim to apply this knowledge to develop personalized approaches to treating diabetes and other metabolic disorders.

Medicine

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Colon Cancer, AIM2, AKT, tumor suppresor

UNC Lineberger Discovery Could Lead to Personalized Colon Cancer Treatment Approach

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In a study published in Nature Medicine, UNC Lineberger Comprehensive Cancer Center researchers report their findings of just how a certain tumor-suppressing protein helps prevent colon cancer. With this discovery, researchers believe they’ve found a possible drug target for colon cancer patients who lack the tumor suppressor.

Medicine

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Colorectal Cancer, Gastroenterology, Genetics, Pharmaceutical Science

New Biomarkers Might Help Personalize Metastatic Colorectal Cancer Treatment

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Metastatic colorectal cancer patients tend to live longer when they respond to the first line of chemotherapy their doctors recommend. To better predict how patients will respond to chemotherapy drugs before they begin treatment, researchers at University of California, San Diego School of Medicine conducted a proof-of-principle study with a small group of metastatic colorectal cancer patients. The results revealed two genes that could help physicians make more informed treatment decisions for patients with this disease.

Medicine

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Mount Sinai Health System, Genomics, Precision Medicine

Mount Sinai Scientists Shed Light on the Motivations of Healthy People Seeking Personal Genome Sequencing

Research will help inform the transition of healthcare to “precision medicine”, where individuals and physicians will routinely obtain and apply genomic information

Medicine

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Personaized Medicine, Pharmacogenetic, Warfarin, Racial And Ethic Differences, dosage guidelines

UAB Study Says Race Influences Warfarin Dose – an Advance for Personalized Medicine

A new report from UAB demonstrates that clinical and genetic factors affecting dose requirements for warfarin vary by race. The study, published online today in Blood, proposes race-specific equations to help clinicians better calculate warfarin dosage.

Medicine

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Life

Business

Social and Behavioral Sciences

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Trending Stories Report for 28 May 2015

Trending news releases with the most views in a single day. Topics include: income inequality, climate change, genetics, cancer, precision medicine, medical imaging, schizophrenia, research funding, molecular biology and skin cancer.

Medicine

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Precision Medicine, Precision Medicine Initiative, Penn Medicine, Perelman School of Medicine at the University of Pennsylvania, University Of Pennsylvania Health System, New England Journal Of Medicine

Dean of Penn’s Perelman School of Medicine: Precision Medicine is “Personalized, Problematic, and Promising”

- The rapidly emerging field of precision medicine is a “disruptive innovation” that offers the possibility of remarkably fine-tuned remedies to improve patient health while minimizing the risk of harmful side effects, says J. Larry Jameson, MD, PhD, dean of the Perelman School of Medicine and executive vice president of the University of Pennsylvania for the Health System, in this week’s issue of the New England Journal of Medicine.

Medicine

Science

Life

Business

Social and Behavioral Sciences

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Trending Stories Report for 26 May 2015

Trending news releases with the most views in a single day. Topics include: genetics and cancer, diabetes and blindness, nanotech, engineering, personalized medicine, energy, and e-cigarettes.

Medicine

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Life

Business

Social and Behavioral Sciences

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Trending Stories Report for 21 May 2015

Trending news releases with the most views in a single day. Topics include: gun regulation, psychology and altruism, big data, threats to coral reefs, extra-terrestrial life, personalized diets, metabolic syndrome and heart health, new drug target to treat arthritis, and archeologists find oldest tools.

Science

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Food Science, Nutrition, futurefood 2050

Nutrition Advancements Ushering in an Era of Personalized Diets for Health

The latest interview series from FutureFood 2050 highlights innovative new research that will shape healthy eating guidelines in the next few decades.







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