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Medicine

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opioid misuse, carfentanil, Prescription Drug Abuse, Enhanced Recovery After Surgery, Pain Management, Fentanyl, Holistic

Six Things You Should Know About the Opioid Crisis

As a primary point of contact for patients receiving anesthesia, procedural sedation, and pain management services, Certified Registered Nurse Anesthetists (CRNAs) are answering the Surgeon General’s call to end the opioid crisis with a more holistic approach to pain management designed to reduce dependence on prescription medications and offering patients greater transparency, understanding and engagement in their own care.

Medicine

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Heart Failure, Cardiomyocytes

Researchers Pinpoint New Drug Target for Heart Failure Patients

Researchers led by Julian E. Stelzer, PhD, associate professor in the department of physiology and biophysics at Case Western Reserve University School of Medicine, have found a new target for drug developers seeking straightforward ways to improve cardiac output in heart failure patients.

Medicine

Life

Social and Behavioral Sciences

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long-term effects of antibiotics, early-life antibiotic exposure, Penicillin

Low-Dose Penicillin in Early Life Induces Long-Term Changes in Behaviour

The researchers report that low-dose penicillin taken late in pregnancy and in early life of mice offspring, changes behaviour and the balance of microbes in the gut. While these studies have been performed in mice, they point to popular increasing concerns about the long-term effects of antibiotics.

Medicine

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MD Anderson Cancer Center, Oncora Medical, Precision Medicine, Radiation Oncology

MD Anderson, Oncora Medical Team Up to Fight Cancer with Precision Medicine Alliance

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Oncora Medical, a precision radiation oncology software company, and The University of Texas MD Anderson Cancer Center, today announced a strategic alliance focusing on building the next generation of precision medicine software for radiation oncology.

Medicine

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Drug Combination Shows Benefit in RAS-Driven Cancers

Dana-Farber Cancer Institute scientists report a number of patients in a small study with RAS-driven lung, ovarian, and thyroid cancers got long-term clinical benefit from a combination of two drugs that targeted molecular pathways controlled by the RAS gene.

Medicine

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ENDO 2017, Endocrine Society, Menopausal Hormone Therapy, Menopause, Bioidentical Hormones, Compounding, Hot Flash, Hot Flashes, Phase 3 clinical trial

New Natural Estrogen-Progesterone Capsule Reduces Postmenopausal Hot Flashes

A natural, or bioidentical, combined estradiol-progesterone capsule (TX-001HR) significantly decreases the frequency and severity of moderate to severe hot flashes in postmenopausal women, the Replenish study finds. Results of this phase 3, randomized, placebo-controlled, multicenter trial will be presented Monday at ENDO 2017, the Endocrine Society’s 99th annual meeting in Orlando, Fla.

Medicine

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Estetrol (E4), Prostate Cancer, Testosterone Levels, ENDO 2017, Endocrine Society, Endocrinology, Cancer, Men's Health, Prostate Cancer Treatment

Estetrol (E4) Shows Promise as a Safe, Effective Drug for Use in Advanced Prostate Cancer

The natural fetal estrogen estetrol, also called E4, is being tested as a new drug that may help treat advanced prostate cancer, according to an ongoing industry-sponsored study from the Netherlands. The final results will be presented in a poster on Saturday, April 1, at ENDO 2017, the annual scientific meeting of the Endocrine Society, in Orlando, Fla.

Medicine

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AACR, AACR 2017, Metformin, Statins, SEER database, Medicare, Pancreatic Cancer, New Jersey, Rutgers University, Diabetes, Cholesterol

Examination of Diabetes and Cholesterol Drugs in Pancreatic Cancer Mortality Shows Improved Survival with Use of One More Than the Other

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Research has shown that by themselves, the diabetes drug metformin and cholesterol-lowering drugs known as statins are associated with reduced cancer mortality, but little is known about the effect on pancreatic cancer mortality when these drugs are taken together. Investigators at Rutgers Cancer Institute of New Jersey examined SEER Medicare data to further explore this approach and found that exposure to statins for these patients was significantly associated with reduced overall mortality.

Medicine

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Julie Brahmer, Cancer, Immunotherapy, drug, nivolumab, Lung Cancer, Johns Hopkins, Clinical Trial

Patients with Lung Cancers Responsive to Immunotherapy Drug Beat Standard Odds of Survival

More than seven years after the start of one of the first clinical trials of the immunotherapy drug nivolumab, researchers at the Johns Hopkins Kimmel Cancer Center report that the five-year survival estimate for a limited subset of people with advanced nonsmall cell lung cancer taking the drug is 16 percent, compared with a historical survival rate for that group of 1 to 4 percent.

Medicine

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Social and Behavioral Sciences

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Study Examines Public Understanding of Drug Rationing Amid AIDS Epidemic

A new study examines what young adults in Balaka, Malawi think about how anti-retroviral drugs are distributed amid an AIDS epidemic in the African nation.







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