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Medicine

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Emily Kendall, arbs, TB, Regimen, Treatment, MDR

Computer Model Predicts Potential Impact of Short-Course Therapy Against Multidrug-Resistant TB

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Johns Hopkins researchers have developed a computer simulation that helps predict under which circumstances a new short-course treatment regimen for drug-resistant tuberculosis could substantially reduce the global incidence and spread of the disease.

Medicine

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HIV, Hepatitis C, Sovaldi, Harvoni, Biomedical Science, Pharmacetical

Bad Combination: Hepatitis C and HIV Medications Can Interact Adversely When Used Together

University of Rhode Island pharmacy professor has discovered potential complications when Hepatitis C and HIV drugs are used in combination with additional medications to combat co-infections.

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Antibiotics resistance

Researchers’ Findings Offer Clue on How to Block Biofilm Shields of Bacterial Infections

An investigation by Southern Research biologists reveals for the first time that fatty acids known as oxylipins play a critical role in the formation of the biofilm shield that protects disease-causing bacteria from antibiotics.

Medicine

Science

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Antibiotic Resistance, scientist profile, Profile, Microbiome, Drug Resistant Bacteria, Gut commensal microbiota

The Irresistible Resistome: How Infant Diapers Might Help Combat Antibiotic Resistance (Sort of)

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Biochemist Gautam Dantas inspects what’s deposited on infant diapers for clues about antibiotic resistance.

Medicine

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Last-Line Antibiotics Are Failing

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On the occasion of the 9th European Antibiotic Awareness Day, the European Centre for Disease Prevention and Control (ECDC) is releasing its latest EU-wide data on antibiotic resistance and antibiotic consumption.

Science

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antibiotic resisistance, Antibiotics, E. Coli, Bacteria, supercomputering, Drug Discovery, efflux pumps, Proteins, Modeling And Simulation, High Performace Computing

Supercomputer Simulations Help Develop New Approach to Fight Antibiotic Resistance

Supercomputer simulations at the Department of Energy’s Oak Ridge National Laboratory have played a key role in discovering a new class of drug candidates that hold promise to combat antibiotic resistance. In a study led by the University of Oklahoma with ORNL, the University of Tennessee and Saint Louis University, lab experiments were combined with supercomputer modeling to identify molecules that boost antibiotics’ effect on disease-causing bacteria.

Medicine

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Infection, Critical Care, ICU, Public Health, Patient Care

Candida auris Emerging Form of Serious Infections.

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Medicine

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Medicine, Drugs, Public Health

Gene Mutations May Increase Adverse Event Risk in Older Adults Taking Multiple Meds

Gene mutations that affect drug metabolism may explain higher hospitalization rates for some older adults taking multiple medications, according to researchers from Columbia University.

Medicine

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Ribosome, catalytic center, chloramphenicol, Linezolid

Two Antibiotics Fight Bacteria Differently Than Thought

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Two widely prescribed antibiotics — chloramphenicol and linezolid — may fight bacteria in a different way from what scientists and doctors thought for years, University of Illinois at Chicago researchers have found. Instead of indiscriminately stopping protein synthesis, the drugs put the brakes on the protein synthesis machinery only at specific locations in the gene.

Medicine

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New Insight on Cytomegalovirus Infection, Breakthrough Therapy for Patients with Giant Cell Arteritis, Zika Infection May Affect Adult Brain Cells and More in the Cell Biology News Source

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