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Medicine

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Chlamydia, Azithromycin, Doxycycline, Drug Adherence

UAB Study Confirms Efficacy of Major Chlamydia Drug

In one of the most tightly controlled trials ever conducted of drugs used to treat sexually transmitted infections, researchers at UAB have confirmed that azithromycin remains effective in the treatment of urogenital chlamydia.

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Untested, Unapproved Compounded Hormone Prescriptions Reach 26 to 33 Million a Year

Despite the risks, the number approaches that for FDA-approved hormone therapies.

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Should Pregnant Women Stop Taking Antidepressants After New JAMA Study Shows Increased Risk of Autism?

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Novel Drug Approach Could Improve Outlook in High-Risk Leukemia

Researchers at Penn State College of Medicine, working with Chinese and American colleagues, have discovered a novel way to enhance and restore cancer suppressor activity in B-cell acute lymphoblastic leukemia, resulting in better outcomes in a pre-clinical model of the disease.

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University of Arkanas for Medical Sciences, Nature, Senescent cells, Nature Medicine, cellular senescence, Radiation, Oxidative Stress, ABT-263, Daohong Zhou, University of Arkansas for Medical Sciences College of Pharmacy, UAMS College of Pharmacy, UAMS, Division of Radiation Health, Aging, Pharmacological, Bone Marrow, Irradiation

‘Toxic’ Cells Thought to Drive the Late Effects of Radiation and Diseases of Aging Can Be Cleared with a Drug

Researchers from the University of Arkansas for Medical Sciences (UAMS) and other institutions are reporting the discovery of the first broad spectrum drug that can potently kill senescent (or aging) cells in culture and effectively clear the cells in animals by specifically targeting a pathway that is critical for the survival of senescent cells.

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GPCRs, signal transduction mechanisms, single-molecule fluorescence spectroscopy, Type 2 Diabetes, Drug Discovery, Asthma, Obesity

TSRI Scientists Show How Drug Molecules Regulate a Medically Important Protein

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A new study, led by scientists at The Scripps Research Institute, shows how different pharmaceutical drugs hit either the “on” or “off” switch of a signaling protein linked to asthma, obesity and type 2 diabetes.

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Recently Approved Heart Drug Poses Potential Risk to Brain & Eye, Temple Researcher Warns

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Patients with mild heart failure stand to benefit from a new drug that can halt the progression of their disease and reduce their risk of cardiovascular-related death. But the drug -- a tablet that combines the agents valsartan and sacubitril, sold under the trade name Entresto by drugmaker Novartis -- may be too good to be true, according to Arthur M. Feldman, MD, PhD, Executive Dean of the Lewis Katz School of Medicine at Temple University (LKSOM), Chief Academic Officer of the Temple University Health System, and Laura H. Carnell Professor of Medicine at LKSOM.

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San Antonio Breast Cancer Symposium, Breast Cancer, Palbociclib , Paclitaxel, Metastasis, Penn Medicine, abramson cancer center

One-Two Punch of Palbociclib and Paclitaxel Shows Promise Against Advanced Breast Cancer in Penn Study

Combining the new breast cancer drug palbociclib with paclitaxel (Taxol) shrank tumors in nearly half of patient with estrogen-receptor (ER) positive breast cancer, according to new research from the Perelman School of Medicine at the University of Pennsylvania. The results will be presented Saturday at the 2015 San Antonio Breast Cancer Symposium (Abstract P6-13-08). A second study (Abstract P4-13-04), to be presented Friday provides new clues to how breast cancer develops resistance to the palbociclib, a common occurrence among many patients who take the drug.

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Researchers Create World’s First Ibuprofen Patch - Delivering Pain Relief Directly Through Skin

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Researchers at the University of Warwick have worked with Coventry-based Medherant, a Warwick spinout company, to produce and patent the World’s first ever ibuprofen patch delivering the drug directly through skin to exactly where it is needed at a consistent dose rate.

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Epilepsy, Seizure, Gene Abnormality, Gene Activity

Seattle Children’s Researchers Identify Drug That Could Suppress Intractable Epilepsy

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Scientists at Seattle Children’s Research Institute have found a way to rapidly suppress epilepsy in mouse models by manipulating a known genetic pathway using a cancer drug currently in human clinical trials for the treatment of brain and breast cancer.







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