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Medicine

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Systems Biology, Systems & Computational Biology, Computational Biology, Pharmacology, Drugs

An Innovative Algorithm is Helping Scientists Decipher How Drugs Work Inside the Body

Researchers at Columbia University Medical Center (CUMC) have developed a computer algorithm that is helping scientists see how drugs produce pharmacological effects inside the body. The study, published in the journal Cell, could help researchers create drugs that are more efficient and less prone to side effects, suggest ways to regulate a drug's activity, and identify novel therapeutic uses for new and existing compounds.

Medicine

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Perelman School of Medicine at the University of Pennsylvania, Residency education, Physician Training, Brand Name Drugs, Prescription, Statin Drug

Penn Study Finds Link between Physician Training and Brand Name Prescribing

Physicians in training are twice as likely to order a costly brand-name statin (used to lower blood cholesterol levels) when supervised by senior physicians who prefer those medications in their own practice, according to a new study led by researchers at the Perelman School of Medicine at the University of Pennsylvania and published online in the Journal of General Internal Medicine.

Medicine

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Menopausal, Menopausal Hormone Therapy, Menopausal Symptoms, Menopausal Women, Menopause, Hormone Replacement Therapy, Hormone Replacement, Estrogen, Estrogen Discovery, Estrogen Based Therapy

Experimental Drug Could Treat Hot Flashes, Other Symptoms of Menopause Without Harmful Side Effects

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Researchers have discovered an experimental medication that treats hot flashes and other menopausal symptoms without the life-threatening risks of hormone replacement therapy, according to a team led by a UNT Health Science Center scientist.

Medicine

Science

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Biomedical, Biomed, Lasers, Biology, Medicine & Health, GPCR, X-ray science, SLAC National Accelerator Laboratory, Stanford University, Linac Coherent Light Source, Stanford Synchrotron Radiation Lightsource, Structural Biology, LCLS , G protein-coupled receptors , Arrestin, Rhodopsin

Long-Sought Discovery Fills in Missing Details of Cell 'Switchboard'

A biomedical breakthrough in the journal Nature reveals never-before-seen details of the human body’s cellular switchboard that regulates sensory and hormonal responses. The work is based on an X-ray laser experiment at the Department of Energy’s SLAC National Accelerator Laboratory.

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Life

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Social and Behavioral Sciences

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New Target to Treat Depression, Sound Waves to Combat Tumors, and Improving Blood Vessels with Age, Top Stories 22 July 2015

Other topics include nursing research, treating hep C and HIV, and more

Medicine

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Warfarin, Atrial Fibrillation, Irregular Heart Beat, Irregular Heart Rhythm, Anticoagulant

Popular New Anticoagulants Drive Increase in Atrial Fibrillation Treatment

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Popular new blood thinners may be behind a surge in doctor visits to treat an irregular heartbeat, according to a new study from the University of Michigan Cardiovascular Center. The heavily advertised medicines make managing atrial fibrillation simpler than older therapies like Warfarin. Among the new players, the most prescribed direct oral anticoagulant is Xarelto.

Medicine

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Hematology, Research, Clincial Trial, HIV, Hepatitis C

New Drug Combination Treats Hepatitis C Patients Also Infected with HIV

Researchers at the University of California, School of Medicine found a new combination that effectively treats hepatitis C (HCV) patients co-infected with human immunodeficiency virus type 1 (HIV).

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Examination of Use of Diabetes Drug Pioglitazone and Risk of Bladder Cancer

Although some previous studies have suggested an increased risk of bladder cancer with use of the diabetes drug pioglitazone, analyses that included nearly 200,000 patients found no statistically significant increased risk, however a small increased risk could not be excluded, according to a study in the July 21 issue of JAMA.

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Antibiotic Use and Decrease in INR Levels Among Patients Taking Vitamin K Antagonists

Researchers have found an association between treatment with the antibiotic dicloxacillin and a decrease in international normalized ratio (INR; a measure of blood coagulation) levels among patients taking the vitamin K antagonists warfarin or phenprocoumon, according to a study in the July 21 issue of JAMA.

Medicine

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UVA Cancer Center, UVA, University Of Virginia Health System, Cancer, Breast Cancer, adjuvant hormone therapy, public health sciences, Study, Research, Cancer Treatment, Appalachia, Appalachia health care, Health Care Access, Affordable Care Act , Affordable Care Act (ACA), health care barriers

Life-Saving Breast Cancer Drugs Going Untaken in Appalachia

Nearly a third of breast cancer survivors in Appalachia are not taking the critical, potentially life-saving follow-up treatment – despite having insurance that would pay for it, a troubling new study has found.







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