Berkeley Lab scientists have discovered the details of an unconventional coupling between a bacterial protein and a mineral that allows the bacterium to breathe when oxygen is not available.
A team of biologists has found an unexpected source for the brain’s development, a finding that offers new insights into the building of the nervous system.
Leaders of the Center for Biorenewable Chemicals are proposing a new model for creating, applying and commercializing chemicals made from biomass. The model calls for identifying “bioprivileged molecules” that offer unique properties.
Hengbin Wang and colleagues describe a key role for a protein called RSF1 in silencing genes. Besides the molecular biology details, the researchers also showed that disruption of RSF1 expression in the embryos of African clawed frogs caused severe developmental defects in the tadpoles.
Argonne and Columbia researchers reveal new significance to a decades-old chemical reaction theory, increasing our understanding of the interaction of gases, relevant to combustion and planetary atmospheres.
A group of researchers has developed an approach to efficiently produce antibodies that can bind to two different target molecules simultaneously, a long-desired innovation in the field of cancer immunotherapy. The details will be published in the Sept. 1 issue of the Journal of Biological Chemistry.
Ian A. Blair, PhD, an internationally recognized expert on applying mass spectrometry, has won the 2017 Founders’ Award from the Division of Chemical Toxicology of the American Chemical Society.
With this breakthrough, the high-performance polymer now could theoretically be used in any shape, size, or structure. And not just within the aerospace industry. The same material can be found in scores of electronic devices, including cell phones and televisions.
Removing a single gene from the brains of mice and zebrafish causes these animals to become more anxious than normal. Researchers from University of Utah Health show that eliminating the gene encoding Lef1 disrupts the development of certain nerve cells in the hypothalamus that affect stress and anxiety. These results are the first implication that Lef1 functions in this brain region to mediate behavior, knowledge that could one day prove useful for diagnosing and treating human brain disorders.
Still uses the NMR spectrometer to conduct his research on plant extracts he procured from the National Cancer Institute (NCI) Active Repository Program.
Under the leadership of Rutgers University-New Brunswick scientist Dr. Joachim Kohn, a civilian research program established by the U.S. Department of Defense to focus on regenerative medicine for the treatment of battlefield injuries has made great strides that culminated in a total face transplant performed at the Cleveland Clinic in May.
A research team from Stony Brook University and the Lawrence Berkeley National Laboratory developed a computational model explaining how certain molecules fold and bind together to grow and evolve from chemistry to biology.
A team of chemists has created a series of three-dimensional structures that take a step closer to resembling those found in nature. The work offers insights into how enzymes are properly assembled, or folded, which could enhance our understanding of a range of diseases that result from these misfolded proteins.
A fast, simple blood test for ulcerative colitis using infrared spectroscopy could provide a cheaper, less invasive alternative for screening compared to colonoscopy, which is now the predominant test, according to a study between the Department of Physics and Astronomy and the Institute for Biomedical Sciences at Georgia State University.
The public's help is being enlisted in the Microbiome Immunity Project, what's thought to be the biggest study to date of the human microbiome — the communities of bacteria and other microbes that live in and on the human body, where they influence our health.
Mosquitoes aren’t just blood thirsty. They also have a sweet tooth, relying on plant nectar to get the sugar they need to survive. Exploiting this weakness, scientists have developed an environmentally friendly eradication method. The new, inexpensive technique tricks these annoying pests into gorging themselves on insecticides laced with a concoction that mimics the sweet-smelling scents and aromas that they find irresistible. It could bolster efforts to suppress malaria, Zika and other mosquito-borne diseases worldwide.
The world’s shortest race by distance — a fraction of the width of a human hair — was run on gold and silver tracks, and took a whopping 30 hours. Given that the vehicles were invisible to the naked eye, your typical racing fan might have missed it. But the April “nanorace” was a huge success for scientists working at the nanoscale. It spurred interest in molecular machines and led to a surprising new discovery, reports the team that entered a nano-sized “monster truck.”
Using plants and trees to make products such as paper or ethanol leaves behind a residue called lignin, a component of plant cell walls. That leftover lignin isn’t good for much and often gets burned or tossed into landfills. Now, researchers report transforming lignin into carbon fiber to produce a lower-cost material strong enough to build car or aircraft parts.
Cross-disciplinary experts who study the mitochondria will convene at the APS “Physiological Bioenergetics: Mitochondria from Bench to Bedside” conference August 27–30 in San Diego. “While mitochondria are traditionally known as the powerhouse of the cell, accumulating studies demonstrate that the shape, movement and function of these organelles control much more in the cell beyond energy levels,” said Sruti Shiva, PhD, researcher at the University of Pittsburgh and chair of the conference organizing committee.
Transition metal silicides are promising for future developments in electronic devices, but fundamental aspects of the chemical bonding between their transition metal atoms and silicon remain poorly understood. One of the most important, but poorly known, properties is the strength of these chemical bonds -- the thermochemical bond dissociation energy. Researchers from the University of Utah have investigated this, and in this week’s The Journal of Chemical Physics, they present their findings for a number of specific compounds.
Plutonium has more verified and accessible oxidation states than any other actinide element, an important insight for energy and security applications.
Imagine you’re on your way to Mars, and you lose a crucial tool during a spacewalk. Not to worry, you’ll simply re-enter your spacecraft and use some microorganisms to convert your urine and exhaled carbon dioxide (CO2) into chemicals to make a new one. That’s one of the ultimate goals of scientists who are developing ways to make long space trips feasible.
Diabetes is a tough disease to manage. Oral medications, insulin shots, close monitoring of blood sugar, dietary changes and exercise can all factor into a person’s treatment regimen. Now researchers are exploring a novel, simpler approach: implanting a polymer sponge into fat tissue. Their study has shown that in obese mice with symptoms resembling Type 2 diabetes, the implant reduced weight gain and blood-sugar levels — by getting the fat to “talk” again.
“What’s in your water?” has become an increasingly fraught question for many people in the U.S. and around the world. Getting the answer isn’t always easy or cheap. Today, scientists are reporting that they are using the familiar “coffee-ring effect” to analyze multiple components in a single drop of water easily, quickly and cheaply. And someday, the public could use the method to test their own tap water.
Photosynthesis provides energy for the vast majority of life on Earth. But chlorophyll, the green pigment that plants use to harvest sunlight, is relatively inefficient. To enable humans to capture more of the sun’s energy than natural photosynthesis can, scientists have taught bacteria to cover themselves in tiny, highly efficient solar panels to produce useful compounds.
Licorice roots have a diverse and flavorful history, having been used in ancient Egyptian times as a tea and in traditional Chinese medicines, all the way to today as a flavoring agent and as an ingredient in some licorice candies. Some women now take licorice extracts as supplements to treat hot flashes and other menopausal symptoms. But scientists caution that the substance could pose a health risk by interacting with medications.
The least appreciated part of an avocado could soon undergo a trash-to-treasure transformation. In a first-of-its-kind study, scientists report that avocado seed husks, which are usually discarded along with the seed, are hidden gold mines packed with a previously unrecognized plethora of chemical compounds. They say these compounds could eventually be used to treat a host of debilitating diseases, as well as to enhance the allure of cosmetics, perfumes and other consumer goods.
Substance abuse is a continuing problem in the U.S., particularly with heroin and other opioids, to the point of being an epidemic. Treatments exist, but far too often patients relapse with devastating impacts on themselves and those around them. Now, scientists report that they have made progress toward a vaccine against the effects of fentanyl, a synthetic opioid, in combination with heroin.
Molten lava, volcanic ash, modern grime, salt, humidity. The ancient painting of a Roman woman has been through it all, and it looks like it. Scientists now report that a new type of high-resolution X-ray technology is helping them discover just how stunning the original portrait once was, element-by-element. The technique could help conservators more precisely restore this image, as well as other ancient artworks.
Coral reefs can’t seem to catch a break. Not only are rising temperatures wreaking havoc with their environment, but emerging evidence suggests that a certain sunblock component in many lotions that may help protect humans from developing skin cancer is a coral killer. Now, researchers have developed a biodegradable bead that can soak up the sunblock ingredient, oxybenzone, like a thirsty sea sponge. They hope to use the agent to clean up seawater at beaches.
Detecting food and cosmetic spoilage and contamination. Identifying new medicinal plants in a remote jungle. Authenticating tea and wine. Scientists have developed a low-cost, portable, paper-based sensor that can potentially carry out all of these functions with easy-to-read results.
Sometimes it seems as if fresh fruits, vegetables and meats go bad in the blink of an eye. Consumers are left feeling frustrated, often turning to less expensive processed foods that last longer but are less nutritious. Now scientists report that they have developed a packaging film coated with clay nanotubes packed with an antibacterial essential oil.
From smart socks to workout clothes that measure exertion, wearable body sensors are becoming the latest “must-have” technology. Now scientists report they are on the cusp of using silk, one of the world’s most coveted fabrics, to develop a more sensitive and flexible generation of these multi-purpose devices that monitor a slew of body functions in real time.
Elite athletes work hard to excel in sports, but they may also get a natural edge from the bacteria that inhabit their digestive tracts. Scientists have now tapped into the microbiome of exceptional runners and rowers, and have identified particular bacteria that may aid athletic performance. The goal is to develop probiotic supplements that may help athletes — and even amateur fitness enthusiasts — recover from a tough workout or more efficiently convert nutrients to energy.
Whether to perform surgery on a fetus is a heart-wrenching decision. This type of surgery involves penetrating the highly delicate amniotic sac, increasing health risks to the fetus. Now researchers report the development of a glue, inspired by the tenacious grip of mussels on slippery rocks, that could one day help save the lives of the youngest patients.
Soldiering in arctic conditions is tough. Protective clothing can be heavy and can cause overheating and sweating upon exertion. And hands and feet can grow numb despite wearing such gear. To keep military personnel more comfortable and battle-ready in bitterly cold climes, scientists are now conducting research aimed at creating high-tech fabrics that heat up when powered and that capture sweat. These fabrics could also conceivably make their way to consumer clothing in the future.
To improve viewing pleasure, companies have developed television — and tablet screens — that include quantum dots to enhance brightness and color. Some quantum dots are made with potentially harmful metals, which could leach into the environment when the device is discarded. But other TVs made with less hazardous nanomaterials require more energy to make.
Group B strep (GBS) bacteria remain the leading cause of severe infections in newborns worldwide. Now researchers have found that although the pathogen can be transmitted to infants through breastfeeding, some mothers produce protective sugars in their milk that could help prevent infection. They also report that the sugars can act as anti-biofilm agents, which is the first example of carbohydrates in human milk having this function.
Researchers from ETH Zurich and the University of Vienna have discovered a type of bacteria that uses tiny daggers to prevent itself from being eaten by amoebae. The scientists also resolved the three-dimensional structure of the mechanism that allows the micro-daggers to be shot quickly.
New findings challenge existing dogma that neurons release fixed amounts of chemical signal at any one time and could have implications for brain disorders including Parkinson's and schizhophrenia.
ECS OpenCon will be the Society’s first, large community event to discuss the future of how research is designed, shared, vetted, and disseminated, with the ultimate goal of making scientific progress faster. Featuring vocal advocates in the open movement, ECS OpenCon will examine the intersection of advances in research infrastructure, the researcher experience, funder mandates and policies, as well as the global shift that is happening in traditional scholarly communications.
A flick of a switch, and electrochromic films change their colors, making sunglasses, windows, and mirrors tint, or textiles flip their shades. Now they can be applied more safely and more commonly thanks to an innovative chemical process that makes them water soluble.
A $597,380 grant from the National Science Foundation will fund SLU scientist Paul Bracher, Ph.D., and his research team as they study what life might look like on other planets - or, here on earth - if it began in oil.
With their remarkable electrical and optical properties, along with biocompatibility, photostability and chemical stability, gold nanoclusters are gaining a foothold in a number of research areas, particularly in biosensing and biolabeling. An international research team has now shown that the fluorescence is an intrinsic property of the gold nanoparticles themselves. The researchers used Au20, gold nanoparticles with a tetrahedral structure. Their findings were reported this week in The Journal of Chemical Physics.