People with RA who stop taking methotrexate treatment for just two weeks after they have a seasonal flu shot can improve the vaccine’s efficacy without increasing RA disease activity, according to new research findings presented this week at the 2017 ACR/ARHP Annual Meeting in San Diego.
Researchers have developed a vaccine candidate that protects against multiple co-circulating strains of H3N2 influenza isolated over five seasons following testing in mouse and ferret models.
Egg-based production causes virus to target bird cells, making vaccine less effective.
Australia has seen its worst flu season on record and could indicate a rough season for the United States.
Researchers at Vanderbilt University Medical Center are leading an international effort to develop a universal influenza vaccine that would protect everyone against all strains of the flu anywhere in the world.
A new flu forecasting tool built by scientists at the University of Chicago aims to make better predictions by combining data about how the virus spreads with an estimate of how much the current virus evolved compared to recent years.
It’s human nature to be afraid of pain. UCLA Health offers advice on how to get through the flu shot.
In 2013, an influenza virus began circulating among poultry in China. It caused several waves of human infection and as of late July 2017, nearly 1,600 people had tested positive for avian H7N9. Nearly 40 percent of those infected had died. In 2017, Yoshihiro Kawaoka of the University of Wisconsin-Madison received a sample of H7N9 virus isolated from a patient in China who had died of the flu. He and his research team subsequently began work to characterize and understand it.
Two recent studies have set the research groundwork for new avenues to treat influenza and anthrax poisoning. The studies employed a series of experiments to identify key pathways and mechanisms previously unknown or overlooked in the body’s defenses, and possible treatments already developed.
St. Jude Children’s Research Hospital investigators said the results reinforce the importance of hand washing and other measures to help protect vulnerable patients from influenza infections.
A new mouse study found that, even in immunized animals, noroviruses can escape the immune system and still spread by hiding out in an extremely rare type of cell in the gut.
Certain proteins in the influenza virus remain constant year after year. Researchers at Cornell University are taking one of those conserved proteins, Matrix-2 (M2), and packaging it in a nanoscale, controlled-release “capsule” in an attempt to create a quick-acting, long-lasting, multi-strain vaccine against pandemic influenza A.
U.S. Olympic and Paralympic athletes and staff who traveled to Rio de Janeiro, Brazil, for the 2016 Summer Games did not become infected with Zika virus but did test positive for other tropical, mosquito-borne viral infections, including West Nile Virus, Dengue Fever and Chikungunya. Results from the University of Utah Health-led study will be reported at IDWeek, a national infectious disease conference being held in San Diego.
If you diabetes and haven’t been vaccinated, it’s time to reconsider. Flu can be more serious than you realize, and health officials say there are early signs that this flu season will be a bad one.
Using an influenza infection model in mice, researchers find a particular population of immune cells develops during the later stages of the immune response to the influenza. These cells, called T follicular regulatory cells, prevent the generation of self-reactive antibody responses.
A new study by researchers has identified an innovative strategy for treating influenza, and perhaps other infectious diseases as well. Scientists showed that a small protein called retrocyclin-101 (RC-101) could potentially improve the symptoms and mortality associated with the flu and possibly other types of infectious illness as well.
Each year, the flu season is a bit of a guessing game. While much is left to chance, some things can be done to plan for and prevent influenza, which is responsible for thousands of deaths each year nationwide.
A collaboration among research institutions, private industry, and the US Government will develop a tetravalent vaccine to protect against four viruses that can be fatal
The same countries hard hit by Zika virus – which can cause brain damage in babies infected before birth – are also home to dengue virus. Washington University School of Medicine in St. Louis researchers report that they have found an antibody that protects against both viruses. These findings, in mice, could be a step towards an antibody-based preventative drug to protect fetuses from brain damage, while also protecting their mothers from both Zika and dengue disease.
Cells can be programmed like a computer to fight cancer, influenza, and other serious conditions – thanks to a breakthrough in synthetic biology by the University of Warwick.
Researchers will use the NIH grant to study whether they can harness an unusual type of immune cell in pigs to treat and prevent influenza viruses in animals and humans.
Influenza vaccination rates in children may have decreased for the 2016-2017 influenza season because of a recommendation by the Centers for Disease Control and Prevention (CDC) that the nasal spray version of the vaccine not be used, according to Penn State College of Medicine researchers.
ASU Biodesign Institute scientist Qiang “Shawn” Chen has led his research team to develop the world’s first plant-based Zika vaccine that could be more potent, safer and cheaper to produce than any other efforts to date.
Researchers have discovered new methods that could improve treatment for infectious diseases by enabling earlier detection of influenza outbreaks and curtailing inappropriate antibiotic usage. The findings were presented today at the 69th AACC Annual Scientific Meeting & Clinical Lab Expo in San Diego.
Researchers led by St. Jude Children’s Research Hospital have identified a genetic variation associated with influenza severity and the supply of killer T cells that help patients fight the infection.
A new study in mice shows that females vaccinated before pregnancy and infected with Zika virus while pregnant bear pups who show no trace of the virus. The findings offer the first evidence that an effective vaccine can protect vulnerable fetuses from Zika infection and resulting injury.
The scientific textbook depiction of the flu virus is about to get a facelift, due to a University of Pittsburgh School of Medicine team’s discovery that a model of the influenza genome architecture untouched since the 1970s isn’t so perfect after all. The finding could give scientists the opportunity to better predict pandemics and find new ways to disrupt the flu virus.
A drug that modulates the placenta’s normal barrier to infection protects the fetus from Zika infection, according to a study of pregnant mice from Washington University School of Medicine in St. Louis. The drug is already used in pregnant women to treat malaria.
Scientists have solved the structure of a protein that helps a common respiratory virus evade the immune system. The team, led by researchers at Washington University School of Medicine in St. Louis, have identified critical parts of the protein that could be targeted with drugs or vaccines, opening up the possibility of preventing or treating an infection that sickens thousands of babies and elderly people every year.
A quarter of countries in sub-Saharan Africa receive very little funding for research into malaria despite having high malaria-related death rates, according to a new study led by the University of Southampton
At the Texas A&M College of Veterinary Medicine & Biomedical Sciences (CVM),veterinarians are working to educate pet parents about the recent outbreak of canine influenza in Georgia and Florida that could affect your dog.
Scientists at The Scripps Research Institute (TSRI) have shown that for the virus that causes the flu, two wrongs can sometimes make a right.
Zika viral load and the degree of Zika symptoms during pregnancy are not necessarily associated with problems during pregnancy or fetal abnormalities at birth. The presence of antibodies to previously acquired dengue fever also is not necessarily linked to abnormalities during pregnancy or at birth.
A team of scientists in the Pacific Northwest has solved the 3-D structure of 1,000 proteins from more than 70 organisms that cause infectious disease in people. The proteins come from microbes that cause several serious diseases, including tuberculosis, Listeria, Giardia, Ebola, anthrax, C. diff., Legionella, Lyme, chlamydia and the flu.
The world may be closer to knowing why Ebola spreads so easily thanks to a team of researchers from Tulane University and other leading institutions who discovered a new biological activity in a small protein from the deadly virus.
After high-risk individuals, immunizing children and the elderly will have the greatest overall benefit when there are limited vaccine resources, Virginia Tech researchers found.
St. Jude Children’s Research Hospital scientists have used a drug being developed to fight solid tumors to restore normal metabolism in flu-infected cells and reduce viral production without the threat of drug resistance
Notre Dame Researchers have discovered a way to make influenza visible to the naked eye, by engineering dye molecules to target a specific enzyme of the virus.
Doctors and researchers in Southampton have developed a novel way of using a swab test which can rapidly diagnose flu and other viral infections in patients with severe respiratory conditions – resulting in shorter courses of antibiotics and less time in hospital.
As the Zika virus continues to spread rapidly across the globe, it might pose a particular risk to people previously infected with two related viruses, dengue and West Nile, researchers at the Icahn School of Medicine at Mount Sinai have found. Their study, published in the journal Science, may help explain the severe manifestations of Zika virus infection observed in specific populations, including those in South America.
A team of researchers from the National University of Singapore has uncovered hidden vulnerabilities on the surface of the dengue virus.
They’re called TIPs and their task would be to infiltrate and outcompete influenza, HIV, Ebola and other viruses. Soon, Rutgers’ Laura Fabris will play a key role in a project aimed at designing TIPs – therapeutic interfering particles to defuse the flu. For the first time in virology, Fabris and her team will use imaging tools with gold nanoparticles to monitor mutations in the influenza virus, with unprecedented sensitivity, when it enters cells. Fabris will soon receive a $820,000 grant from the Defense Advanced Research Projects Agency (DARPA). It’s part of a four-year, $5.2 million INTERfering and Co-Evolving Prevention and Therapy (INTERCEPT) program.
Supplemental funding will allow three partner institutions to perform additional site visits, conduct more education and training courses, as well as build a special pathogens research network.
A new study led by scientists at The Scripps Research Institute (TSRI) is the first to show exactly how the drug Arbidol stops influenza infections. The research reveals that Arbidol stops the virus from entering host cells by binding within a recessed pocket on the virus.
Spread holiday greetings, not the flu, this season.
A new testing methodology based on metagenomics could accelerate the diagnosis of foodborne bacterial outbreaks, allowing public health officials to identify the microbial culprits in less than a day.
Colder temps during the first months of fall are a stark reminder that people should start thinking about how to prevent the influenza virus, or the flu.
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