Newswise — Here are highlights from the fall issue of Discovery’s Edge, Mayo Clinic's research magazine. You may cite and link to this publication as often as you wish. Reprinting is allowed with proper attribution. Please include the following subscription information as your editorial policies permit: Visit Discovery’s Edge for subscription information.

Data Mining to Redesign Critical Care ServicesUsing informatics, epidemiology, systems engineering and in-depth medical-record studies, this groundbreaking work is improving patient safety in ICUs and significantly cutting the cost of health care. http://discoverysedge.mayo.edu/critical-care-data-mining/

Zebrafish GeneticsMolecular biologists are using zebrafish to investigate new treatments for cancer and nicotine addiction, and as a foundational way to get students excited about science.http://discoverysedge.mayo.edu/zebrafish-genetics/

Diabetes and Heart Damage — an iPS Cell ApproachBuilding on recent discoveries in converting normal cells into cells with stem cell characteristics, Mayo researchers are exploring the potential of iPSCs or induced pluripotent stem cells in regenerating organs. Among the goals: alleviate heart damage and Type 1 diabetes. http://discoverysedge.mayo.edu/ips-regenerative-medicine/

Brain Cancer: Angling for its OriginsWhat causes brain tumors? Using statistics from Mayo’s enormous patient databases, genetics researchers are learning how genetic mutations and environmental triggers increase the risk of developing brain cancer. http://discoverysedge.mayo.edu/brain-cancer-origins/

Discovery’s Edge, Mayo Clinic’s online research magazine, highlights stories of leading medical investigators. Many features cover ongoing projects long before they reach the journals. Science writers and medical reporters seeking story ideas will want to check out the articles, which span a wide range of conditions and feature visuals they can use in their own publications.

About Mayo ClinicMayo Clinic is the first and largest integrated, not-for-profit group practice in the world. Doctors from every medical specialty work together to care for patients, joined by common systems and a philosophy of “the needs of the patient come first.” More than 3,300 physicians, scientists and researchers and 46,000 allied health staff work at Mayo Clinic, which has sites in Rochester, Minn.; Jacksonville, Fla.; and Scottsdale/Phoenix, Ariz. Collectively, the three locations treat more than half a million people each year. To obtain the latest news releases from Mayo Clinic, go to www.mayoclinic.org/news. For information about research and education, visit www.mayo.edu. MayoClinic.com (www.mayoclinic.com) is available as a resource for your health stories.