Newswise — Toronto, ON, Canada, April 30, 2014 – A new study presenting data from 17 cardiac surgical centers in Virginia, representing 100 surgeons and 99% of cardiac operations performed in the state, demonstrates that, even today, significant variations – among surgeons and hospitals - still exist in the performance of mitral valve repair vs replacement for moderate to severe mitral regurgitation. Significant associations were observed between the propensity for MV repair and both institutional and surgeon annual volume, although increasing surgeon volume appears to be the much stronger predictor.

Damien J. LaPar, MD, MSc, of the Division of Thoracic and Cardiovascular Surgery at the University of Virginia (Charlottesville), is presenting the results of this research at the 94th AATS Annual Meeting in Toronto, ON, Canada on April 30, 2014.

When the mitral valve (MV) leaks, blood can flow backward or “regurgitate” into the upper heart chamber, leading to decreased blood flow to the rest of the body. To compensate, the heart may try to pump harder, and this can result in congestive heart failure. When regurgitation is severe, the standard of care treatment is MV surgery. Two options are available: mitral value repair or replacement.

Professional associations such as the American College of Cardiology and the American Heart Association recommend mitral valve surgery over medical management for severe mitral regurgitation. Yet, only 50% of patients meeting the ACC/AHA guidelines for surgical treatment undergo surgery. Furthermore, while MV repair is associated with superior perioperative outcomes and reduced mortality compared to replacement, it appears to be underutilized.

In this large, multi-institutional retrospective study from the Virginia Cardiac Surgery Quality Initiative, more than 4,000 patients were evaluated, and 60% underwent MV repair. Significant variations were seen in MV repair rates among hospitals (35-70% of MV procedures) and surgeons (0-90%).

The results suggest that what type of surgery a patient received depended in part on how experienced the surgeon was. After adjustment for baseline preoperative patient risk, when the propensity to perform an MV repair was plotted against surgeon volume, it became apparent that there was an “inflection point” of increased probability for mitral repair when the average annual surgeon volume (a surrogate for surgeon experience) exceeded approximately 20 surgeries a year. Surgeons who performed more than 20 MV surgeries a year were between 3 and 4 times more likely to perform a repair than replacement compared to those who operated less than 20 times a year.

Dr. LaPar suggests that the results may have important future implications on patient referral of care and quality measure assessment. “In the upcoming era of percutaneous MV repair technology, surgeon volume and expertise as a gatekeeper should dictate access to this technology and the decisions for approach to MV repair.”

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NOTES FOR EDITORS“Mitral valve repair rates correlate with surgeon and institutional experience,” by Damien J. LaPar, MD, MSc, Gorav Ailawadi, MD, James Isbell, MD, MSc, Ivan K. Crosby, MD, John A. Kern, MD, Jeffrey B. Rich, MD, Alan M. Speir, MD, Irving L. Kron, MD. Presentation at the 94th AATS Annual Meeting. April 26-30, 2014, Toronto, ON, Canada during the Adult Cardiac Surgery Session on April 30, 8:04 AM ET. http://aats.org/annualmeeting

For more information contact Nicole Baritot, Managing Editor, AATS Scientific Publications, at +1 978-299-4520 or [email protected]. Journalists wishing to interview Dr. LaPar may contact him at +1 434-924-9307 or [email protected]. The presentation abstract is located at http://www.aats.org/annualmeeting/Program-Books/2014/79.cgi.

ABOUT THE AUTHORSInvestigators for the Virginia Cardiac Surgery Quality Initiative:Damien J. LaPar, MD, MSc, University of Virginia, Charlottesville, VAGorav Ailawadi, MD, University of Virginia, Charlottesville, VAJames Isbell, MD, MSc, University of Virginia, Charlottesville, VAIvan K. Crosby, MD, University of Virginia, Charlottesville, VAJohn A. Kern, MD, University of Virginia, Charlottesville, VAJeffrey B. Rich, MD, Sentara Heart Hospital, Norfolk, VAAlan M. Speir, MD, Inova Heart and Vascular Institute, Falls Church, VAIrving L. Kron, MD, University of Virginia, Charlottesville, VA

ABOUT THE AMERICAN ASSOCIATION FOR THORACIC SURGERY (AATS)The American Association for Thoracic Surgery (AATS) is an international organization of over 1,300 of the world’s foremost thoracic and cardiothoracic surgeons, representing 35 countries. AATS encourages and stimulates education and investigation into the areas of intrathoracic physiology, pathology and therapy. Founded in 1917 by a respected group of the last century’s earliest pioneers in the field of thoracic surgery, the AATS’ original mission was to “foster the evolution of an interest in surgery of the Thorax.”

One hundred years later, the AATS continues to be the premiere association among cardiothoracic surgeons. The purpose of the Association is the continual enhancement of the ability of cardiothoracic surgeons to provide the highest level of quality patient care. To this end, the AATS encourages, promotes, and stimulates the scientific investigation and study of cardiothoracic surgery. Visit www.aats.org.

Meeting Link: 94th AATS Annual Meeting, April 2014