Newswise — Worldwide, the number of people with Alzheimer’s disease will hit 115 million by 2050, according to the World Health Organization. Scientists, health officials, policymakers, and the public are asking if anything can slow down the disease. Several U.S. trials will soon test whether specific drugs can prevent Alzheimer's, but what about lifestyle changes, such as eating better and exercising more? As reported on the Alzheimer Research Forum, key researchers from three large trials have come together under the European Dementia Prevention Initiative (EDPI), to collaborate, share data, and even design future studies.

Among these three ongoing trials are the PreDIVA (Prevention of Dementia by Intensive Vascular Care) and FINGER (Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability) trials. Both of these studies aim to find out if intense treatment of cardiovascular risk factors, along with better exercise and healthy lifestyle changes, will lower the risk of dementia. A third trial, the Multi-Domain Alzheimer's Prevention Trial (MAPT) asks whether omega-3 fatty acids plus lifestyle factors such as nutrition, exercise, and cognitive activities help stave off mental decline.

As these trials progress, EDPI scientists hope to combine data where possible, expand the number of study participants, and determine how best to design future such trials. EDPI will soon receive a grant to design and carry out another five-year prevention study that involves counseling through the internet. Read more about EDPI and its various studies in Alzforum's coverage .

About Alzforum: The Alzheimer Research Forum, founded in 1996, is the web's most dynamic scientific community dedicated to understanding Alzheimer disease and related disorders. Access to the web site is free to all. The Forum’s editorial priorities are as diverse as the needs of the research community. The web site reports on the latest scientific findings, from basic research to clinical trials; creates and maintains public databases of essential research data and reagents; and produces discussion forums to promote debate, speed the dissemination of new ideas, and break down barriers across the numerous disciplines that can contribute to the global effort to cure Alzheimer's disease.

The ARF team of professional science writers and editors, information technology experts, web developers and producers all work closely with its distinguished and diverse Advisory Board to ensure a high quality of information and services. The Alzheimer Research Forum is an independent nonprofit organization supported by grants and individual donations. The web site does not endorse any specific product or scientific approach.

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