Latest News from: Sanford Burnham Prebys

Filters close
Newswise: With the help of naked mole rats, Xiao Tian seeks to expose and explain the epigenetic drivers of aging
Released: 14-Feb-2024 8:00 AM EST
With the help of naked mole rats, Xiao Tian seeks to expose and explain the epigenetic drivers of aging
Sanford Burnham Prebys

Xiao Tian, Ph.D., who recently joined Sanford Burnham Prebys as an assistant professor in the Degenerative Diseases Program, focuses on epigenomic changes and deterioration that influence age-related diseases.

Newswise: A new 3D bioprinted model offers a novel tool to study common liver disease, and perhaps find an effective treatment
Released: 23-Jan-2024 11:05 AM EST
A new 3D bioprinted model offers a novel tool to study common liver disease, and perhaps find an effective treatment
Sanford Burnham Prebys

Metabolic dysfunction–associated steatohepatitis or MASH (formerly known as nonalcoholic steatohepatitis) is an inflammatory, liver-scarring disease that affects 1.5% to 6.5% of all U.S. adults.

Newswise: Sanjeev Ranade wants to get to the heart of congenital disease
Released: 22-Jan-2024 6:00 AM EST
Sanjeev Ranade wants to get to the heart of congenital disease
Sanford Burnham Prebys

Sanjeev S. Ranade, Ph.D., who joined the faculty of Sanford Burnham Prebys this month as an assistant professor in the Development, Aging and Regeneration program, studies how proteins called transcription factors (TFs) specifically control the development and function of cardiac cells — and what happens when things go wrong.

Newswise: When T cells and macrophages talk, Kelly Kersten listens
Released: 17-Jan-2024 2:05 PM EST
When T cells and macrophages talk, Kelly Kersten listens
Sanford Burnham Prebys

Kelly Kersten, Ph.D., who joined Sanford Burnham Prebys this month as an assistant professor in the Cancer Metabolism and Microenvironment program, studies the interactions between immune cells and their microenvironment to better understand how they contribute to anti-tumor immune responses.

Newswise: Shengjie Feng channels the powers of cryogenic electron microscopy
Released: 16-Jan-2024 12:05 PM EST
Shengjie Feng channels the powers of cryogenic electron microscopy
Sanford Burnham Prebys

Shengjie Feng, Ph.D. is an expert in cryo-electron microscopy, a Nobel Prize-winning imaging technology capable of creating stop-action movies of proteins and other biomolecules jostling and connecting with each other while mitochondria and other organelles generate energy, assemble new molecules and transport cargo. At Sanford Burnham Prebys, Feng will use cryo-EM to reveal new ways to stop or prevent cancers.

   
Newswise: Sanford Burnham Prebys continues unprecedented recruitment of early-career scientists
Released: 19-Dec-2023 5:05 PM EST
Sanford Burnham Prebys continues unprecedented recruitment of early-career scientists
Sanford Burnham Prebys

Continuing its rapid and dramatic recruitment of emerging, top-tier researchers, Sanford Burnham Prebys has hired two more highly regarded early-career scientists: Angela Liou, M.D., a specialist in pediatric oncology and hematology; and Xueqin Sherine Sun, Ph.D., a cancer biologist and genome engineer.

Newswise: When tumors manipulate their mitochondria, Kevin Tharp will be there to stop them.
Released: 18-Dec-2023 6:05 AM EST
When tumors manipulate their mitochondria, Kevin Tharp will be there to stop them.
Sanford Burnham Prebys

Kevin Tharp, Ph.D., who recently joined Sanford Burnham Prebys as an assistant professor and principal investigator in the Cancer Metabolism & Microenvironment program, studies the interplay between mitochondrial metabolism and the physical properties of the tumor microenvironment.

Newswise: Sanford Burnham Prebys elects Lori Moore to its Board of Trustees
Released: 12-Dec-2023 10:05 AM EST
Sanford Burnham Prebys elects Lori Moore to its Board of Trustees
Sanford Burnham Prebys

Sanford Burnham Prebys today announced that Lori Moore will join the Institute’s Board of Trustees.

Newswise: Similarity between vitamin B12 loss and multiple sclerosis revealed
Released: 8-Dec-2023 7:05 PM EST
Similarity between vitamin B12 loss and multiple sclerosis revealed
Sanford Burnham Prebys

In a new study, published online December 8, 2023 in Cell Reports, researchers at Sanford Burnham Prebys, with collaborators elsewhere, describe a novel molecular link between vitamin B12 and MS that takes place in astrocytes – important non-neuronal glial cells in the brain.

Newswise: Study reveals Zika’s shape-shifting machinery—and a possible vulnerability
Released: 8-Dec-2023 5:05 PM EST
Study reveals Zika’s shape-shifting machinery—and a possible vulnerability
Sanford Burnham Prebys

Viruses have limited genetic material—and few proteins—so all the pieces must work extra hard. Zika is a great example; the virus only produces 10 proteins.

Newswise:Video Embedded from-tobacco-to-alcohol-to-opioids-sanford-burnham-prebys-researchers-are-pursuing-novel-leads-and-promising-therapies-to-treat-addiction
VIDEO
Released: 16-Nov-2023 3:05 PM EST
From tobacco to alcohol to opioids, Sanford Burnham Prebys researchers are pursuing novel leads and promising therapies to treat addiction
Sanford Burnham Prebys

Tens of millions of Americans are addicted to illicit drugs, alcohol, tobacco and other substances including opioids, with both immediate and long-term harm to not just themselves, but also family, friends and society.

Newswise: “DNA loops” in pediatric brain tumors double relapse risk
Released: 14-Nov-2023 9:05 AM EST
“DNA loops” in pediatric brain tumors double relapse risk
Sanford Burnham Prebys

A study of newly created databases of medulloblastoma has found that patients with tumors containing circular extrachromosomal DNA—loops of DNA found outside of regular chromosomes—are twice as likely to relapse and three times as likely to die within five years of diagnosis.

Newswise: Inhibiting an enzyme associated with aging could help damaged nerves regrow and restore strength
Released: 11-Oct-2023 7:05 PM EDT
Inhibiting an enzyme associated with aging could help damaged nerves regrow and restore strength
Sanford Burnham Prebys

Scientists at Stanford University School of Medicine and Sanford Burnham Prebys have demonstrated a new way to accelerate recovery from peripheral nerve injury by targeting an enzyme that was thought to be responsible for muscle wasting with aging.

Newswise: Copycat nutrient leaves pancreatic tumors starving
7-Oct-2023 2:05 PM EDT
Copycat nutrient leaves pancreatic tumors starving
Sanford Burnham Prebys

A study led by scientists at Sanford Burnham Prebys suggests an entirely new approach to treat pancreatic cancer. The research shows that feeding tumors a copycat of an important nutrient starves them of the fuel they need to survive and grow.

Newswise: New grant funds study of very aggressive childhood brain cancers driven by circular pieces of DNA
Released: 14-Sep-2023 8:05 AM EDT
New grant funds study of very aggressive childhood brain cancers driven by circular pieces of DNA
Sanford Burnham Prebys

Lukas Chavez, Ph.D., has received $3.2 million from the National Institutes of Health to study how unique DNA circles found in cancer cells drive deadly pediatric brain tumors. The research aims to expose how the circular pieces of DNA contribute to therapy resistance and open new therapeutic avenues to improve the lives of people affected by these devastating diseases.

Newswise: US Department of Defense backs Cosimo Commisso’s pancreatic cancer research
Released: 7-Sep-2023 5:00 AM EDT
US Department of Defense backs Cosimo Commisso’s pancreatic cancer research
Sanford Burnham Prebys

Cosimo Commisso, Ph.D., has received a grant from the Department of Defense for $1 million to advance the research of a small molecule that kills pancreatic cancer cells by disrupting their pH equilibrium.

Newswise: Timothy Huang awarded $2.6M to solve Alzheimer’s disease puzzle
Released: 6-Sep-2023 5:00 AM EDT
Timothy Huang awarded $2.6M to solve Alzheimer’s disease puzzle
Sanford Burnham Prebys

With the help of a new grant from the National Institutes of Health for more than $2.6 million, Assistant Professor Timothy Huang, Ph.D., will continue his research on the role of the brain’s immune cells on the risk of developing Alzheimer’s disease.

Newswise: Sanford Burnham Prebys Cancer Center earns merit extension from NCI
Released: 9-Aug-2023 4:05 PM EDT
Sanford Burnham Prebys Cancer Center earns merit extension from NCI
Sanford Burnham Prebys

Sanford Burnham Prebys’ Cancer Center has received a rare and prestigious Merit Extension Award from the National Cancer Institute (NCI), recognizing and rewarding its earlier accomplishments as well as current research plans. The award extends the center’s current 5-year Cancer Center Support Grant (CCSG) for an additional two years.

Newswise: Big Data. Bigger Opportunities.
Released: 8-Aug-2023 1:20 PM EDT
Big Data. Bigger Opportunities.
Sanford Burnham Prebys

New and rapidly developing technologies, such as cryo-electron (cryo-EM) and artificial intelligence, are providing the tools to revolutionize biomedical research, but you need scientists who know how to use them

   
Newswise: New grant seeks to parse how the variegated nature of human breast cancer tumors helps cancer cells resist treatment
Released: 4-Aug-2023 8:00 AM EDT
New grant seeks to parse how the variegated nature of human breast cancer tumors helps cancer cells resist treatment
Sanford Burnham Prebys

The National Cancer Institute (NCI) has awarded a 5-year, $2.7 million grant to researchers at Sanford Burnham Prebys to investigate and elucidate the underlying cellular mechanisms that drive the most common form of breast cancer.

Newswise: This sugar kills honeybees—it could also help fight cancer
Released: 18-Jul-2023 3:00 AM EDT
This sugar kills honeybees—it could also help fight cancer
Sanford Burnham Prebys

Research from Sanford Burnham Prebys and the Osaka International Cancer Institute has shed new light on the anti-cancer properties of mannose, a sugar that is crucial to many physiological processes in humans and is also known to inhibit the growth of cancer cells.

Newswise: New genes implicated in deadly heart defect
Released: 17-Jul-2023 7:10 PM EDT
New genes implicated in deadly heart defect
Sanford Burnham Prebys

By identifying genes in patients and testing their effects in fruit flies, researchers from Sanford Burnham Prebys have found new genes that contribute to hypoplastic left heart syndrome.

Newswise: Breast cancer by age: Study reveals early mutations that predict patient outcomes
25-Jun-2023 9:00 PM EDT
Breast cancer by age: Study reveals early mutations that predict patient outcomes
Sanford Burnham Prebys

A study led by researchers at Sanford Burnham Prebys has found that in young women, certain genetic mutations are associated with treatment-resistant breast cancer.

Newswise: Computational biology superstar Sanju Sinha joins Sanford Burnham Prebys
Released: 13-Jun-2023 12:00 PM EDT
Computational biology superstar Sanju Sinha joins Sanford Burnham Prebys
Sanford Burnham Prebys

Sanju Sinha, Ph.D., has joined Sanford Burnham Prebys as an assistant professor in the Cancer Molecular Therapeutics Program to continue his research on cancer development and drug discovery. He comes to Sanford Burnham Prebys from the Cancer Data Science Lab at the National Cancer Institute (NCI), where he trained to leverage the power of artificial intelligence to discover new drugs to prevent cancer.

Newswise: Pumping the brakes on autoimmune disease
Released: 5-Jun-2023 11:00 AM EDT
Pumping the brakes on autoimmune disease
Sanford Burnham Prebys

A new study from researchers at Sanford Burnham Prebys and Eli Lilly and Company describes the science behind an autoimmune disease treatment in a Phase 2 clinical trial.

Newswise: New algorithm can predict diabetic kidney disease
Released: 15-May-2023 5:00 AM EDT
New algorithm can predict diabetic kidney disease
Sanford Burnham Prebys

Researchers from Sanford Burnham Prebys and the Chinese University of Hong Kong have developed a computational approach to predict whether a person with type 2 diabetes will develop kidney disease. The findings could help doctors prevent or better manage kidney disease in people with type 2 diabetes.

Newswise: Reviving exhausted T cells to tackle immunotherapy-resistant cancers
Released: 3-May-2023 5:55 PM EDT
Reviving exhausted T cells to tackle immunotherapy-resistant cancers
Sanford Burnham Prebys

One of the biggest goals of immunotherapy is to reverse T cell exhaustion to boost the immune system’s ability to destroy cancerous cells. Researchers at Sanford Burnham Prebys studying melanoma have found a new way to make this happen.

Newswise: Taking a 3D view of the genome may help treat pediatric brain cancers
Released: 27-Apr-2023 10:50 AM EDT
Taking a 3D view of the genome may help treat pediatric brain cancers
Sanford Burnham Prebys

Researchers led by Sanford Burnham Prebys assistant professor Lukas Chavez, Ph.D., are leveraging the latest technology to take a never-before-seen look at ependymoma, one of the deadliest pediatric brain tumors. By visualizing how the genome is organized and arranged within tumor cells, they were able to reveal genes in tumors that may be future targets for therapy. The results appear in Nature Communications.

Newswise: Charles Spruck awarded $1.7M to advance “ancient virus” treatment for prostate cancer
Released: 25-Apr-2023 12:00 PM EDT
Charles Spruck awarded $1.7M to advance “ancient virus” treatment for prostate cancer
Sanford Burnham Prebys

With the help of a new grant from the U.S. Department of Defense for more than $1.7 million, Associate Professor Charles Spruck, Ph.D., will advance an innovative therapeutic approach for metastatic prostate cancer. Known as viral mimicry, the approach tricks the body into thinking that it has a viral infection, stimulating an immune response that can help the body fight cancer.

Newswise: Heart attack study could change the game in regenerative medicine
Released: 29-Mar-2023 3:50 PM EDT
Heart attack study could change the game in regenerative medicine
Sanford Burnham Prebys

Sanford Burnham Prebys researchers have identified a group of proteins that could be the secret to cellular reprogramming, an emerging approach in regenerative medicine in which scientists transform cells to repair damaged or injured body tissues.

Newswise: Sanford Burnham Prebys researchers team up to discover potential pancreatic cancer drugs
Released: 27-Mar-2023 6:30 PM EDT
Sanford Burnham Prebys researchers team up to discover potential pancreatic cancer drugs
Sanford Burnham Prebys

Cosimo Commisso, Ph.D., and Susanne Heynen-Genel, Ph.D., have received a grant from the National Cancer Institute (NCI) to advance a new treatment approach for pancreatic cancer.

   
Newswise: Sanford Burnham Prebys elects Professor Nicholas Cosford to its Board of Trustees
Released: 9-Mar-2023 1:20 PM EST
Sanford Burnham Prebys elects Professor Nicholas Cosford to its Board of Trustees
Sanford Burnham Prebys

Sanford Burnham Prebys today announced that Professor Nicholas Cosford, Ph.D., will join the Institute’s Board of Trustees.

   
Newswise: Sanford Burnham Prebys earns highest rating from Charity Navigator
Released: 14-Feb-2023 8:55 AM EST
Sanford Burnham Prebys earns highest rating from Charity Navigator
Sanford Burnham Prebys

A top rating on Charity Navigator means Sanford Burnham Prebys is among the most trusted charities nationwide in terms of financial health and accountability.

Newswise: New treatment approach for prostate cancer could stop resistance in its tracks
Released: 3-Feb-2023 2:10 PM EST
New treatment approach for prostate cancer could stop resistance in its tracks
Sanford Burnham Prebys

For the first time, researchers have discovered that prostate cancer can be killed by targeting a single enzyme. The findings could help address the growing threat of prostate cancer resistance and could also lead to improved treatments for other cancers.

Newswise: Incurable liver disease may prove curable
Released: 4-Jan-2023 4:00 PM EST
Incurable liver disease may prove curable
Sanford Burnham Prebys

Research has shown for the first time that the effects of Alagille syndrome, an incurable genetic disorder that affects the liver, could be reversed with a single drug. The study, published in the Proceedings of the National Academy of Sciences, has the potential to transform treatment for this rare disease and may also have implications for more common diseases.

Newswise: Childhood cancer trailblazer Lukas Chavez joins Sanford Burnham Prebys
Released: 20-Dec-2022 9:00 AM EST
Childhood cancer trailblazer Lukas Chavez joins Sanford Burnham Prebys
Sanford Burnham Prebys

Lukas Chavez, Ph.D., has joined Sanford Burnham Prebys as an assistant professor in the Tumor Initiation and Maintenance Program to continue his research on chromatin and gene regulation in childhood brain cancers.

Newswise:Video Embedded liver-cancer-study-encourages-caution-with-certain-gene-therapies
VIDEO
5-Dec-2022 7:30 PM EST
Liver cancer study encourages caution with certain gene therapies
Sanford Burnham Prebys

A newly discovered link between protein misfolding and liver cancer could help improve gene therapy for hemophilia.

Newswise: Sanford Burnham Prebys announces start of Phase 2 clinical trial of DS-1211 in individuals with PseudoXanthoma Elasticum
30-Nov-2022 5:50 PM EST
Sanford Burnham Prebys announces start of Phase 2 clinical trial of DS-1211 in individuals with PseudoXanthoma Elasticum
Sanford Burnham Prebys

A Phase 2 clinical trial has started of DS-1211 in individuals with Pseudoxanthoma Elasticum (PXE), a rare multisystem genetic disease that causes calcium deposits in soft tissue resulting in considerable morbidity. DS-1211 is a potential first-in-class small molecule developed through a research collaboration between Daiichi Sankyo and Sanford Burnham Prebys.

Newswise: Yu Xin (Will) Wang joins Sanford Burnham Prebys to advance regenerative medicine
28-Nov-2022 12:00 PM EST
Yu Xin (Will) Wang joins Sanford Burnham Prebys to advance regenerative medicine
Sanford Burnham Prebys

Molecular biologist Yu Xin (Will) Wang, Ph.D., has joined Sanford Burnham Prebys as an assistant professor in the Development, Aging, and Regeneration Program to uncover the ways muscle, nerve and immune cells work together to overcome disease.

Newswise: Randal J. Kaufman among the world’s most highly cited researchers
Released: 21-Nov-2022 2:25 PM EST
Randal J. Kaufman among the world’s most highly cited researchers
Sanford Burnham Prebys

Sanford Burnham Prebys professor Randal J. Kaufman, Ph.D. was included on Clarivate’s 2022 Highly Cited Researchers list, a global ranking of influential researchers based on the number of times their work has been cited in peer-reviewed publication over the last decade.

Newswise: Sanford Burnham Prebys selected for participation in National Cancer Institute Chemical Biology Consortium
Released: 16-Nov-2022 4:40 PM EST
Sanford Burnham Prebys selected for participation in National Cancer Institute Chemical Biology Consortium
Sanford Burnham Prebys

For the third time, Sanford Burnham Prebys has been selected by the Frederick National Laboratory for Cancer Research, currently operated by Leidos Biomedical Research, Inc., supporting the NCI Experimental Therapeutics (NExT) Program as a Center for the Chemical Biology Consortium (CBC).

   
Newswise: American Cancer Society to help Sanford Burnham Prebys push the envelope in cancer
Released: 14-Nov-2022 7:25 PM EST
American Cancer Society to help Sanford Burnham Prebys push the envelope in cancer
Sanford Burnham Prebys

Two faculty members from Sanford Burnham Prebys have been awarded grants from the American Cancer Society (ACS), the largest not-for-profit funding body for scientists studying cancer. Associate Professor Cosimo Commisso, Ph.D., and Assistant Professor Svasti Haricharan, Ph.D., each received competitive awards to advance their work on difficult-to-treat cancers.

Newswise: Seeing the Immune System in Full Color
Released: 2-Nov-2022 2:10 PM EDT
Seeing the Immune System in Full Color
Sanford Burnham Prebys

The Flow Cytometry Core at Sanford Burnham Prebys is getting a new piece of state-of-the-art research equipment, thanks to a grant from the National Institutes of Health.

Newswise: Sanford Burnham Prebys Partners with Nation’s Top Cancer Organizations to Endorse Initiative to Increase Lung Cancer Screening in the United States
1-Nov-2022 7:00 AM EDT
Sanford Burnham Prebys Partners with Nation’s Top Cancer Organizations to Endorse Initiative to Increase Lung Cancer Screening in the United States
Sanford Burnham Prebys

Sanford Burnham Prebys has partnered with more than 50 cancer organizations to issue a call to action urging individuals, providers and insurers to increase access to and utilization of low-dose computed tomography (CT) scans for those at high risk for lung cancer.

Newswise:Video Embedded erkki-ruoslahti-wins-america-s-top-biomedical-research-award
VIDEO
Released: 28-Sep-2022 12:00 PM EDT
Erkki Ruoslahti wins America’s top biomedical research award
Sanford Burnham Prebys

Distinguished Professor Emeritus Erkki Ruoslahti, M.D., Ph.D., has been announced as one of three winners of the Albert Lasker Basic Medical Research Award, the most prestigious American award for biomedical research, for his transformational research leading to the discovery of the cell adhesion receptors now known as integrins.

Newswise: Sanford Burnham Prebys researchers awarded $6.4M to advance treatment for substance use disorders
13-Sep-2022 3:15 PM EDT
Sanford Burnham Prebys researchers awarded $6.4M to advance treatment for substance use disorders
Sanford Burnham Prebys

Sanford Burnham Prebys Professor Nicholas Cosford, Ph.D., has been awarded $6.4M from the National Institute on Drug Abuse (NIDA) to test new potential drugs to treat opioid and methamphetamine use disorders. The three-year project will be completed with partners from Wake Forest University School of Medicine and Camino Pharma, LLC.

Newswise: How a single protein could unlock age-related vision loss
Released: 6-Sep-2022 5:05 PM EDT
How a single protein could unlock age-related vision loss
Sanford Burnham Prebys

Research led by Sanford Burnham Prebys professor Francesca Marassi, Ph.D., is helping to reveal the molecular secrets of macular degeneration, which causes almost 90% of all age-related vision loss. The study, published recently in the Biophysical Journal, describes the flexible structure of a key blood protein involved in macular degeneration and other age-related diseases, such as Alzheimer’s and atherosclerosis.

Newswise: Inhibiting key metabolic enzyme shows promise against melanoma
29-Aug-2022 11:00 AM EDT
Inhibiting key metabolic enzyme shows promise against melanoma
Sanford Burnham Prebys

Researchers at Sanford Burnham Prebys, led by Ze’ev Ronai, Ph.D., have shown for the first time that inhibiting a key metabolic enzyme selectively kills melanoma cells and stops tumor growth. Published in Nature Cell Biology, these findings could lead to a new class of drugs to selectively treat melanoma, the most severe form of skin cancer.

Newswise: Peter Adams and Bing Ren awarded $10.6M to create atlas of aging cells
Released: 16-Aug-2022 12:40 PM EDT
Peter Adams and Bing Ren awarded $10.6M to create atlas of aging cells
Sanford Burnham Prebys

Peter Adams, Ph.D., and Bing Ren, Ph.D., have been awarded a new grant from the National Institutes of Health (NIH) to join a multi-institution initiative studying the process of aging.

Newswise: Jianhua Zhao awarded $2.4M to reveal cancer targets through atomic-resolution imaging
Released: 2-Aug-2022 6:05 PM EDT
Jianhua Zhao awarded $2.4M to reveal cancer targets through atomic-resolution imaging
Sanford Burnham Prebys

Assistant Professor Jianhua Zhao, Ph.D., has been awarded a unique and competitive grant from the National Institute of General Medical Sciences (NIGMS), part of the National Institutes of Health (NIH). The five-year, $2.4 million grant aims to give researchers greater research flexibility to work on fundamental questions in biology.



close
0.2492