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Deafness, Hearing, loss, Antibiotics, Blood, iron, Chelators, Aminoglycosides

Common Drugs May Prevent Antibiotic-Induced Deafness

University of Michigan scientists have found that iron chelators can prevent deafness in guinea pigs exposed to antibiotics that damage delicate hair cells in the inner ear. The U-M research could lead to a way to eliminate the threat of deafness to individuals treated with a common class of antibiotics.


Laryngitis, GERD, Heartburn, Asthma, Cancer, Esophagus, Digestive, Health

The State of the Art in Digestive Health

Chronic heartburn/GERD (gastroesophageal reflux disease) can, if left untreated, lead to serious medical problems including asthma, laryngitis and esophageal cancer, according to leading gastroenterologists. To learn more about how to treat chronic heartburn/GERD and prevent any of the associated complications, we invite you to come hear some of the worldís leading experts discuss the most recent research in this area. You will also be able to take an actual endoscopic trip down the esophagus.


Clinical, Trial, Antifungal

Phase II Efficacy Data with Merck's Echinocandin Antifungal

Preliminary results from a Phase II study with Merck's echinocandin antifungal, MK-991 (formerly known as L-743,872), showed efficacy in 85% of patients with Candida esophagitis. The data were presented today at the 37th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) meeting in Toronto, Ontario, Canada.


Medical, Reporters, Symposium, Meeting, Communication

Medical reporting symposium to bring leading journalists to UNC-CH

Some of the nation's leading medical reporters will speak at the University of North Carolina at Chapel Hill Nov. 14-15 in a symposium for working medical journalists and medical communications specialists.


Diabetes, Higher, Heart, Death, rate, for, Angioplasty

Diabetes explains higher heart death rates for recipients of angioplasty

A long-term study shows that individuals whose coronary arteries are obstructed and who are treated with angioplasty have more heart-related deaths than those who undergo bypass surgery.


Protein, Linked, Popped, Aneurysms

Protein linked to "popped" aneurysms

A chemical version of a "balloon-popper" has been identified that may help explain why some aortic aneurysms rupture and others do not. The report appears in today's American Heart Association journal Circulation.


Blood, Thinning, drug, Improves, CLOT, Busting, Treatment

Blood-thinning drug may improve clot-busting treatment, save lives

For treating heart attacks, the blood thinner hirulog is better than heparin when added to a "clot-buster" to dissolve blood clots and reopen clogged arteries, according to a report in today's American Heart Association journal Circulation.


Epilepsy, Genetics, Mouse, Brain, Neurobiology

Epilepsy Research Advance Reported at Jackson Laboratory

Researchers at The Jackson Laboratory report in Cell the development of the first genetic model to exhibit both absence and convulsive epileptic seizures. The "slow wave epilepsy" (swe) mouse promises to be the most authentic model yet for petit mal epilepsy in humans.


Obesity, Agouti Related, Protein, AGRP, Leptin, Mc4 R, Weight

Researchers discover new target for obesity drugs

Using clues from a fat, yellow mouse, researchers at Stanford University School of Medicine and the University of Michigan have identified a new cog in the body's main weight-regulating system. The protein they discovered may join leptin, a protein identified in 1994, as a prime target for the development of drugs to fight obesity, said Dr. Gregory Barsh, an associate professor of pediatrics and genetics at Stanford and the senior author of the study.



Virtual, Reality, Manufacturing, Factory, Chicago, Pharmaceutical, Sustainibility

UIC research brings virtual reality to manufacturing design

Researchers at the University of Illinois at Chicago have incorporated virtual reality technology into a manufacturing design tool that allows the user to visualize and plan a factory while it is still in the design phase. The tool, a computer simulation, is proving its usefulness at Searle, a pharmaceutical company based in Skokie, Ill.

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