Study suggests that weight loss, even if associated with intermittent weight gain, is worthwhile in that there appears to be no harm and possible benefit in terms of cardiovascular outcomes.
The psychosocial care team helps patients and their caregivers and family members address issues including managing distress, depression, anxiety or post-traumatic stress associated with diagnoses and treatments. The team also helps patients and caregivers to feel less overwhelmed and more in control, as well as improving self-care and communication with loved ones and their health care providers.
A mutant gene for a brain protein in a child with autism has been placed into the brains of fruit flies. Fruit flies hosting that gene produce the variant human brain protein and show abnormal behaviors of fear, repetitive activity and altered social interaction, reminiscent of autism impairments.
People of Mexican descent with variants of a certain gene are more at risk for Type 2 diabetes, but the risk of developing the disease does not increase for people of other Hispanic and Latino background groups.
The Centers for Disease Control reports that influenza activity in Alabama is now widespread and likely to increase. Alabama’s Department of Public Health also reports that almost every Alabama county is experiencing significant flu activity. As Alabama and the rest of the country enter the height of flu season, University of Alabama at Birmingham medical caregivers want to remind the public that, if you are normally a healthy person who is experiencing flu-like symptoms — high fever, muscle or body aches throughout the body, exhaustion, and loss of appetite — do not go to the emergency department.
Treatment with the NSAID carprofen triggers subtle low-grade inflammation in the heart and kidneys. The combination of carprofen pretreatment and heart attack magnifies this impact by dysregulating the acute inflammatory response, amplifying inflammation and intensifying the cardiorenal syndrome.
Intensive control of blood pressure in older people significantly reduced the risk of developing mild cognitive impairment, a precursor of early dementia, according to the National Institutes of Health-supported Systolic Blood Pressure Intervention Trial Memory and Cognition in Decreased Hypertension, or SPRINT MIND.
Three ultrasound measurements moderately, but significantly, predict successful arteriovenous fistula maturation. Mature fistulas are vital for hemodialysis, but half fail to mature. This information can facilitate decisions by the clinician, like new surgery or abandonment of the fistula.
Researchers find brain overconnectivity in the unimodal-subcortical connections and brain underconnectivity in the supramodal-subcortical connections for ASD individuals, as compared to a typically developing control group, suggesting a relationship between connectivity and the expression of ASD.
The University of Alabama at Birmingham will launch a new master’s degree in anatomical science this summer to help meet the growing need for anatomists in health care programs and courses.
Researchers have found that, during acute kidney injury in a mouse model, the kidney-resident macrophages are reprogrammed to a developmental state, resembling these same cells when they are found in newborn mice. This reprogramming may be important to promote healing and tissue regeneration.
In an article recently published in JCI Insight, researchers from the University of Alabama at Birmingham and Vanderbilt University have identified checkpoint inhibitor resistance mechanisms in many solid tumor cancers, including melanoma, lung cancer and breast cancer.
This is the first visual function for incident AMD in older adults with normal macular health and early AMD.
Older adults with delayed dark adaptation have a heightened risk for developing AMD within the next few years.
Vision in bright light was known to be relatively preserved late into the disease. Night vision is affected much earlier.
Survivors of childhood Hodgkin lymphoma are at an increased risk of developing an entirely new cancer later in life, according to new research published in Cancer — the American Cancer Society’s international peer-reviewed scientific journal — and conducted at University of Alabama at Birmingham.
Researchers have found a novel, pathogenic entity that is a fundamental link between chronic inflammation and tissue destruction in lungs of patients with COPD. These exosomes from activated neutrophils caused COPD damage when they were instilled into the lungs of healthy mice.
Research published in Immunity describes a mechanism in a mouse model of asthma that supports the hygiene hypothesis — researchers found that infant mice need a higher exposure to a bacterial endotoxin, compared to adult mice, to avoid developing asthma-like reactions to house dust mites.
Using a unique bioinformatics technique developed at UAB, researchers have detected the emergence of new strains of microbes in the human fecal microbiota after obesity surgery. These new strains emerged after surgical disruption of the stomach and upper small intestine.
Investigators from UAB have summarized the impact of the reimbursement gap between Medicaid and private insurance on management and in-hospital outcomes among patients admitted for STEMI.
In a move to maintain revenue and expand opportunities to produce and license new monoclonal antibodies, UAB has outsourced its selection of marketable monoclonal immunoreagents and hybridomas — the cells that produce monoclonal antibodies — to the Birmingham-based SouthernBiotech.
Researchers used NMR to detail how the matrix domain of the Avian Sarcoma Virus Gag protein binds to certain phospholipids. These phospholipids are vital for Gag protein binding to the plasma membrane of a cell, as the virus replicates and takes its first step toward virus formation and budding.
The UAB Department of Biomedical Engineering is first in the state of Alabama to receive the Ruth L. Kirchstein NRSA Institutional Research Training Grant.
West view of the Murlidhar temple at Pardi, built during the Bhosle period, in the late 18th century, Nagpur.An American art history professor could help India preserve some historic religious sculpture and architecture. Cathleen Cummings, Ph.D., associate professor of art history at the University of Alabama at Birmingham, just returned from a research trip in India.
UAB study suggests individuals diagnosed with autism spectrum disorder may not be more prone to cyber phishing attacks compared to those without the disorder.
Researchers show that lung-resident memory B cells establish themselves in the lung soon after influenza infection in mice. Those lung memory B cells respond more quickly to produce antibodies against influenza after re-infection, and establishment requires a local antigen encounter in the lung.
Preclinical experiments by University of Alabama at Birmingham researchers suggest the cancer drugs vorinostat, belinostat and panobinostat might be repurposed to treat infections caused by human papillomaviruses, or HPVs.
Sports medicine physicians at UAB present the first study of spectator injuries at major sporting events. Car and motorcycle racing lead the way. The authors call for more safety measures and a central database to record the occurrence of spectator injuries.
Jessica Martindale’s perfect vision was quickly tested after her infant son inadvertently scratched her cornea. Thankfully, physicians at UAB Callahan Eye Hospital were there to help.
Using freshly resected lung tissue from 21 patients and two distinct mouse models, tuberculosis researchers at the University of Alabama at Birmingham and the Africa Health Research Institute have identified a protein that plays an essential role in host defense against this deadly disease.
For consumers, parents and even teens, understanding terminology and the truth about e-cigarettes can be confusing. UAB physicians debunk common e-cigarette myths with truths.
Mild exposure to a single blast shock wave in a rat model of bTBI is able to induce small but meaningful pathogenic effects that accumulate with time. These effects were detected at the microscopic level. Brain function also changed, as shown by impaired short-term synaptic plasticity.