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Tuesday February 21, 2017, 12:05 PM

Penn and Wistar Researchers Find "Sweet Spot" Where Tissue Stiffness Promotes Cancer's Spread

Wistar Institute

University of Pennsylvania and Wistar scientists have studied the physical feedback mechanisms between cancer cells and their environment and described how this interplay allows the migration and invasion of tumor cells.

Tuesday February 21, 2017, 09:05 AM

Penn Expert Calls for Shorter Radiation Use in Prostate Cancer Treatment

Perelman School of Medicine at the University of Pennsylvania

Men with prostate cancer can receive shorter courses of radiation therapy than what is currently considered standard, according to Justin Bekelman, MD, an associate professor of Radiation Oncology, Medical Ethics, and Health Policy at the University of Pennsylvania's Perelman School of Medicine and Abramson Cancer Center.

Monday February 20, 2017, 03:05 PM

BRCA Gene Plus Breast Cancer History Leads to Preventive Strike Against Pancreatic Cancer

UT Southwestern Medical Center

More than three decades after surviving breast cancer, Susanne Calabrette faced a second scare. In June 2016, an MRI for an unrelated condition revealed she had pancreatic cysts, giving her a chance for a pre-emptive strike against this killer cancer.

Monday February 20, 2017, 01:05 PM

UNC Researcher Finds Safer, Less-Invasive Method of Staging Endometrial Cancer

University of North Carolina Health Care System

A UNC-Chapel Hill researcher has published a study in Lancet Oncology online that identifies sentinel-lymph-node mapping as a safer and less-invasive method of staging endometrial cancer that is equally as accurate as the more traditional lymphadenectomy.

Monday February 20, 2017, 12:05 PM

Protein Once Thought Exclusive to Neurons Helps Aggressive Cancers Grow, Spread, and Defy Death

UT Southwestern Medical Center

How we think and fall in love are controlled by lightning-fast electrochemical signals across synapses, the dynamic spaces between nerve cells. Until now, nobody knew that cancer cells can repurpose tools of neuronal communication to fuel aggressive tumor growth and spread.

Monday February 20, 2017, 11:05 AM

New Approach to Cervical Cancer Care in Botswana Cuts Lag Time Between Treatment and Diagnosis in Half

Perelman School of Medicine at the University of Pennsylvania

Cervical cancer is the leading cause of cancer deaths for women low- and middle-income countries, including Botswana, where 75 percent of cervical cancer patients suffer from advanced forms of the disease. These patients can face wait times as long as five months after diagnosis before receiving lifesaving treatment. A new, multidisciplinary model of cervical cancer care developed by a University of Pennsylvania team based in Botswana cut the delay between diagnosis and treatment by more than 50 percent, according to research published this month in the Journal of Global Oncology.

Monday February 20, 2017, 11:05 AM

Biomarker Predicts Poor Prognosis in African-Americans with Triple-Negative Breast Cancer, Study Finds

Georgia State University

Having high levels of a certain biomarker is linked to poor prognosis in African-American patients with triple-negative breast cancer, while the same biomarker doesn't influence disease outcomes in white patients, according to a new study.

Monday February 20, 2017, 10:05 AM

What Turns Benign Central Nervous System Tumors Deadly

Yale Cancer Center

In a new study, Yale researchers identified genetic abnormalities that mark atypical meningiomas, which have a 40% chance of recurring after surgical removal and are marked by a shorter survival rate than benign tumors.

Friday February 17, 2017, 03:05 PM

Micro-RNA May Amplify Effectiveness of Sorafenib in Difficult Liver Cancer Cases

Sbarro Health Research Organization (SHRO)

Only 25% of patients respond to sorafenib treatment, so researchers have endeavored to understand its mechanism of action and discover a way to boost its effectiveness.

Friday February 17, 2017, 01:00 PM

Researchers Are First to See DNA 'Blink'

Northwestern University

Northwestern University biomedical engineers have developed imaging technology that is the first to see DNA "blink," or fluoresce. The tool enables researchers to study individual biomolecules (DNA, chromatin, proteins) as well as important global patterns of gene expression, which could yield insights into cancer. Vadim Backman will discuss the technology and its applications -- including the new concept of macrogenomics, a technology aiming to regulate the global patterns of gene expression without gene editing -- at the 2017 AAAS annual meeting.

Friday February 17, 2017, 09:00 AM

Tumor Suppressor Promotes Some Acute Myeloid Leukemias, Study Reveals

The Rockefeller University Press

Researchers in Germany have discovered that a tumor suppressor protein thought to prevent acute myeloid leukemia (AML) can actually promote a particularly deadly form of the disease. The study, "RUNX1 cooperates with FLT3-ITD to induce leukemia," which will be published online February 17 in The Journal of Experimental Medicine, suggests that targeting this protein could be an effective treatment for certain AML patients.

Thursday February 16, 2017, 02:05 PM

UAB to Bring Proton Therapy for Advanced Cancer Treatment to Birmingham

University of Alabama at Birmingham

UAB will partner with Proton International to bring proton therapy, one of the most technically advanced forms of cancer-killing radiation, to Alabama. Proton therapy delivers a more precise dose of radiation to a tumor and can avoid damage to healthy surrounding tissue better than conventional X-ray radiation.

Thursday February 16, 2017, 12:00 PM

Scientists Monitor Crosstalk Between Intestinal Microbes and Immune System

Harvard Medical School

Harvard Medical School researchers have successfully "listened in" on the crosstalk between gut microbes and the immune system.

Thursday February 16, 2017, 11:05 AM

Looking Beyond Cancer Cells to Understand What Makes Breast Cancer Spread

Michigan Medicine - University of Michigan

A new study from researchers at the University of Michigan Comprehensive Cancer Center identifies a protein in that microenvironment that promotes the spread of breast cancer cells. It's part of a well-known family of receptors for which promising inhibitors are being developed.

Thursday February 16, 2017, 10:30 AM

Doctors Treat Deadly Cancerous Disorders with Gene-Guided, Targeted Therapy

Cincinnati Children's Hospital Medical Center

Genomic testing of biopsies from patients with deadly, treatment-resistant cancerous blood syndromes called histiocytoses allowed doctors to identify genes fueling the ailments and use targeted molecular drugs to successfully treat them. Researchers report their data in Journal of Clinical Investigation Insight (JCI Insight). They recommend the regular use of comprehensive genomic profiling at diagnosis to positively impact clinical care,

Thursday February 16, 2017, 08:20 AM

Cancer Researchers to Convene for Multidisciplinary Thoracic Cancers Symposium in March

American Society for Radiation Oncology (ASTRO)

The 2017 Multidisciplinary Thoracic Cancers Symposium, co-sponsored by the American Society for Radiation Oncology (ASTRO), the American Society of Clinical Oncology (ASCO) and The Society of Thoracic Surgeons (STS), will feature advances in surgery, radiation therapy, chemotherapy and novel molecular biologic therapies for thoracic malignancies such as lung cancer.

Wednesday February 15, 2017, 03:05 PM

More Patients with Early-Stage Breast Cancer May Be Able to Avoid Chemotherapy in the Future

University of Texas M. D. Anderson Cancer Center

Women with early-stage breast cancer who had an intermediate risk recurrence score (RS) from a 21-gene expression assay had similar outcomes, regardless of whether they received chemotherapy, a new study from The University of Texas MD Anderson Cancer finds.

Wednesday February 15, 2017, 01:30 PM

Study Points to Potential New Brain Cancer Treatment

Yale Cancer Center

A recent Yale study may have found a new way to fight brain cancer.

Wednesday February 15, 2017, 01:05 PM

Genome Analysis Helps Keep Deadly Brain Cancer at Bay for Five Years

Yale Cancer Center

An analysis of a patient's deadly brain tumor helped doctors at Smilow Cancer Hospital identify new emerging mutations and keep a 55-year old woman alive for more than five years, researchers report in the journal Genome Medicine.

Wednesday February 15, 2017, 01:05 PM

'Explosive Growth' of Interventional Oncology Prompts Formation of New Society

Yale Cancer Center

The board of directors for World Conference on Interventional Oncology, a nonprofit association that supports and promotes the field, has established a society to further its mission.

Wednesday February 15, 2017, 01:00 PM

Scientists Discover How the Cells in Skin and Organ Linings Maintain Constant Cell Numbers

University of Utah Health Sciences

Research published today in Nature from scientists at Huntsman Cancer Institute (HCI) at the University of Utah shows how epithelial cells naturally turn over, maintaining constant numbers between cell division and cell death.

Wednesday February 15, 2017, 12:00 PM

DNA Patterns Can Unlock How Glucose Metabolism Drives Cancer, Study Finds

University of California, Los Angeles (UCLA), Health Sciences

Less aggressive cancers are known to have an intact genome--the complete set of genes in a cell--while the genome of more aggressive cancers tends to have a great deal of abnormalities. Now, a new multi-year study of DNA patterns in tumor cells suggests that these aberrant genetic signatures are not random but reflect selective forces in tumor evolution.

Wednesday February 15, 2017, 09:00 AM

Payers Weigh the Implications of Multigene Testing Coverage in New UCSF Study

National Comprehensive Cancer Network(r) (NCCN(r))

A recent study from the UCSF Center for Translational and Policy Research on Personalized Medicine and the UCSF Helen Diller Family Comprehensive Cancer Center identified opportunities to address the barriers to coverage of hereditary cancer panels, as published in JNCCN.

Tuesday February 14, 2017, 04:00 PM

Smoking Cessation Counseling Successful When Paired with Lung Cancer Screening

Georgetown Lombardi Comprehensive Cancer Center

The first successful randomized trial of its kind provides preliminary evidence that telephone-based smoking cessation counseling given to smokers shortly after undergoing lung cancer screening can be effective at helping people stop smoking.

Tuesday February 14, 2017, 11:05 AM

Scripps Florida Collaboration Awarded $3.3 Million to Develop Next-Generation Breast Cancer Therapies

Scripps Research Institute

A pair of scientists from the Florida campus of The Scripps Research Institute (TSRI) have been awarded up to $3.3 million from the National Cancer Institute of the National Institutes of Health (NIH) to create the next generation of breast cancer treatments for the thousands of patients whose current treatment options are limited.

Tuesday February 14, 2017, 10:05 AM

Cancer Survivor and Noted Physician-Scientist Sandra Horning to Receive Roth Award

University of California San Diego Health Sciences

Sandra Horning, MD, Chief Medical Officer and executive vice president of global development for Roche and Genentech, a member of the Roche Group, has been named the 2017 recipient of the Duane Roth Memorial Award, which will be presented February 16 at the annual Industry/Academia Translational Oncology Symposium at UC San Diego Moores Cancer Center.

Tuesday February 14, 2017, 09:00 AM

Johns Hopkins Kimmel Cancer Center Names Benjamin Levy to Lead Medical Oncology Program at Sibley

Johns Hopkins Medicine

Lung cancer specialist Benjamin Levy, M.D., has been named the new clinical director of medical oncology and medical director of thoracic oncology for the Johns Hopkins Kimmel Cancer Center at Sibley Memorial Hospital in northwest Washington, D.C.

Tuesday February 14, 2017, 08:00 AM

Orlando Health's Heart Care and Cancer Care Recognized with Highest Quality Rating

Orlando Health

The Society of Thoracic Surgeons awards Orlando Health a 3 star quality rating for bypass surgery, aortic valve replacement, aortic valve replacement with bypass surgery and lobectomy for lung cancer.

Tuesday February 14, 2017, 08:00 AM

Drug Developed at University of Minnesota Increases Survival in Dogs with Cancer

University of Minnesota College of Veterinary Medicine

Molecular Cancer Therapeutics reports on this treatment for hermangiosarcama

Monday February 13, 2017, 05:00 PM

Drug Used to Combat Pain Medication Side Effects May Help with Gastrointestinal Recovery and Shorten Length of Hospital Stay Following Testicular Cancer Surgery

Rutgers Cancer Institute of New Jersey

A drug given to reduce the side effects of strong post-surgery pain medications resulting in a reduced length of hospital stay for patients who have undergone major gastrointestinal or bladder cancer procedures is found to have similar benefit for some patients undergoing surgery for testicular cancer. An investigator at Rutgers Cancer Institute of New Jersey explored the impact of alvimopan in those patients who underwent RPLND.

Monday February 13, 2017, 12:05 PM

New Study Links 'Mastermind' Gene to Rare Cancer-Causing Tumor

Uniformed Services University of the Health Sciences (USU)

Scientists have discovered a new "mastermind fusion gene" may be associated with a rare cancer-causing tumor - pheochromocytomas ("pheo") and paragangliomas, according to a study published Feb. 13 in Cancer Cell, by researchers at the Uniformed Services University (USU) and the National Cancer Institutes' The Cancer Genome Atlas. This breakthrough discovery could lead to more precise treatment as well as a better understanding of cancer itself.

Monday February 13, 2017, 11:05 AM

Researchers Identify 'Achilles' Heel' of PTEN That Helps Drive Prostate Cancer Progression

Cold Spring Harbor Laboratory

Loss of the protein Importin 11 predicts relapse and metastasis in patients following prostate removal

Monday February 13, 2017, 10:05 AM

Non-Invasive Test Offers Quick Skin Cancer Diagnosis

National Institute of Biomedical Imaging and Bioengineering

Researchers have developed a non-invasive imaging technique that accurately detects skin cancer without surgical biopsy. Multiphoton microscopy of mitochondria accurately identified melanomas and basal cell carcinomas by detecting abnormal clusters of mitochondria in both types of skin cancer.

Monday February 13, 2017, 10:00 AM

NDSU Student Studying Cancer Treatment Wins Three Minute Thesis Competition

North Dakota State University

NDSU students have many opportunities to practice skills they will use in their professional lives. The NDSU Graduate School hosted a Three Minute Thesis Competition to challenge graduate students to effectively communicate complex research to a general audience.

Monday February 13, 2017, 09:05 AM

In-Depth Gene Search Reveals New Mutations, Drug Targets in Rare Adrenal Tumors

Perelman School of Medicine at the University of Pennsylvania

Casting one of the largest genomic nets to date for the rare tumors of the autonomic nervous system known as pheochromocytoma and paraganglioma (PCC/PGL) captured several new mutations driving the disease that could serve as potential drug targets, researchers from Penn Medicine and other institutions reported this week in Cancer Cell.

Monday February 13, 2017, 09:00 AM

Researchers Identify "Achilles' Heel" of Key Anti-Cancer Protein

The Rockefeller University Press

Researchers at Cold Spring Harbor Laboratory in New York have discovered that a protein called Importin-11 protects the anti-cancer protein PTEN from destruction by transporting it into the cell nucleus. The study, "The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein," which will be published online February 13 in The Journal of Cell Biology, suggests that the loss of Importin-11 may destabilize PTEN, leading to the development of lung, prostate, and other cancers.

Monday February 13, 2017, 08:05 AM

Cedars-Sinai, UCLA Scientists Use New 'Blood Biopsies' With Experimental Device to Speed Cancer Diagnosis and Predict Disease Spread

Cedars-Sinai

A team of investigators from Cedars-Sinai and UCLA is using a new blood-analysis technique and tiny experimental device to help physicians predict which cancers are likely to spread by identifying and characterizing tumor cells circulating through the blood.

Friday February 10, 2017, 04:05 PM

Corn, Milk Proteins Make Medicine Easier to Swallow

South Dakota State University

It's all about the layers! Encapsulating a drug in corn protein nanoparticles and then covering with them milk protein can make children's medications better tasting and safer.

Friday February 10, 2017, 01:05 PM

A New Hope for Bladder Cancer Patients

University of Kansas Cancer Center

A bladder cancer drug discovered and developed at The University of Kansas Cancer Center is set to become its first cancer drug to go from bench to bedside.

Friday February 10, 2017, 09:00 AM

Heart-Shaped Cells

NIH, National Institute of General Medical Sciences (NIGMS)

The cellular skeleton protein actin can bind cells together, and also play a number of roles in cancer's invasion into new tissues in the body.

Friday February 10, 2017, 09:00 AM

MD Anderson Designated First Project ECHO Superhub for Oncology

University of Texas M. D. Anderson Cancer Center

Recognizing a critical need to address disparities in cancer care, The University of Texas MD Anderson Cancer Center has been designated as an ECHO superhub for oncology by the ECHO Institute at the University of New Mexico Health Science Center (UNMHSC). MD Anderson is one of just nine ECHO superhub sites in the world and the first focused on oncology.

Thursday February 09, 2017, 07:05 PM

Los Alamos Research on Cancer's Origins Key Part of Huge Grant

Los Alamos National Laboratory

Los Alamos National Laboratory researcher Ludmil Alexandrov has been announced as a member of one of the first four global research teams funded under Cancer Research UK's "Grand Challenge," which seeks to revolutionize the understanding of cancer and its prevention, diagnosis and treatment.

Thursday February 09, 2017, 01:05 PM

An Alternative Theory on How Aspirin May Thwart Cancer

Veterans Affairs (VA) Research Communications

Studies abound that point to a role for plain old aspirin in keeping deadly cancers at bay. While aspirin is not yet part of mainstream treatment for any cancer, it is recommended by the U.S. Preventive Services Task Force for certain adults to help prevent colorectal cancer.

Thursday February 09, 2017, 12:05 PM

Going Bald for Cancer Research

University of Illinois at Chicago

Children's Hospital University of Illinois will host an annual head-shaving event to raise money for the St. Baldrick's Foundation. Staff, physicians and families of children with cancer volunteer each year to have their heads shaved in support childhood cancer research and fellowships.

Wednesday February 08, 2017, 05:05 PM

Genetic Profiling Can Guide Stem Cell Transplantation for Patients with Myelodysplastic Syndrome, Study Finds

Dana-Farber Cancer Institute

A single blood test and basic information about a patient's medical status can indicate which patients with myelodysplastic syndrome (MDS) are likely to benefit from a stem cell transplant, according to new research by scientists at Dana-Farber Cancer Institute.

Wednesday February 08, 2017, 01:05 PM

New Ludwig Research Will Shift How Cancer Diversity and Resistance Are Understood and Studied

Ludwig Cancer Research

Ludwig researchers discover that circular DNA, once thought to be rare in tumor cells, is actually very common and seems to play a fundamental role in tumor evolution

Wednesday February 08, 2017, 11:05 AM

Immunotherapy May Need to Have Its Own Value Model

Yale Cancer Center

Immunotherapy has been a game changer for the oncology field, but typical models used to assess the value of cancer treatments don't take into account the unique characteristics of this therapy, according to experts at the 2016 annual meeting of the Society for Immunotherapy of Cancer (SITC).

Wednesday February 08, 2017, 10:30 AM

Every Diagnosis of Cancer Should Come with One of These, Says Cancer Expert

Sbarro Health Research Organization (SHRO)

"Every cancer diagnosis should come with a referral to genetic counseling," says cancer expert Dr. Antonio Giordano, President of the Sbarro Health Research Organization at Temple University.

Tuesday February 07, 2017, 02:05 PM

Breast Cancer Patients with Dense Breast Tissue More Likely to Develop Contralateral Disease

University of Texas M. D. Anderson Cancer Center

Breast cancer patients with dense breast tissue have almost a two-fold increased risk of developing disease in the contralateral breast, according to new research from The University of Texas MD Anderson Cancer.

Tuesday February 07, 2017, 10:00 AM

16 Aplastic Anemia Patients Free Of Disease After Bone Marrow Transplant and Chemo

Johns Hopkins Medicine

Physicians at the Johns Hopkins Kimmel Cancer Center report they have successfully treated 16 patients with a rare and lethal form of bone marrow failure called severe aplastic anemia using partially matched bone marrow transplants followed by two high doses of a common chemotherapy drug.

Monday February 06, 2017, 03:05 PM

When to See a Doctor About Moles and Changes in Your Skin

University Hospitals Cleveland Medical Center

Monday February 06, 2017, 02:05 PM

MD Anderson to Present Making Cancer History(r) Seminar in Indian Wells

University of Texas M. D. Anderson Cancer Center

The University of Texas MD Anderson Cancer Center returns to Southern California this month with its Making Cancer History(r) Seminar, 3:30-5:30 p.m. Feb. 20 at the Renaissance Indian Wells Resort and Spa, 44400 Indian Wells Lane.

Monday February 06, 2017, 12:05 PM

Yale Study: 1 in 4 Teen E-Cigarette Users Have Tried 'Dripping'

Yale Cancer Center

Yale researchers found in a study that one in four high schoolers who use electronic cigarettes are inhaling vapors produced by dripping e-liquids directly onto heating coils, instead of inhaling from the e-cigarette mouthpiece, possibly increasing exposure to toxins and nicotine.

Monday February 06, 2017, 11:05 AM

Scientists Discover Why Some Cancers May Not Respond to Immunotherapy

University of California, Los Angeles (UCLA), Health Sciences

UCLA scientists have discovered that people with cancers containing genetic mutations JAK1 or JAK2, which are known to prevent tumors from recognizing or receiving signals from T cells to stop growing, will have little or no benefit from the immunotherapy drug pembrolizumab. This early-stage research has allowed them to determine for the first time why some people with advanced melanoma or advanced colon cancer will not respond to pembrolizumab, an anti-PD-1 treatment.

Monday February 06, 2017, 11:00 AM

Researchers Identify 'Synthetic Essentiality' as Novel Approach for Locating Cancer Therapy Targets

University of Texas M. D. Anderson Cancer Center

A new method has been found for identifying therapeutic targets in cancers lacking specific key tumor suppressor genes. The process, which located a genetic site for the most common form of prostate cancer, has potential for developing precision therapy for other cancers, such as breast, brain and colorectal, say researchers at The University of Texas MD Anderson Cancer Center. Study results were published in the Feb. 6 online issue of Nature.

Monday February 06, 2017, 11:00 AM

New Technique Slashes Diagnosis Time During Brain Surgery

Michigan Medicine - University of Michigan

Neurosurgeons want the quickest, most accurate information to help them make decisions during brain tumor surgery. A new technique could help.

Monday February 06, 2017, 09:15 AM

Monell Center Receives Grant to Characterize Distinctive Odor of Ovarian Cancer

Monell Chemical Senses Center

A new grant from the Robert J. Kleberg, Jr. and Helen C. Kleberg Foundation will allow Monell scientists and collaborators to confirm initial findings of a unique odor pattern for ovarian cancer. The multi-disciplinary team will use the information to customize a portable screening device that can diagnose the deadly disease at early, treatable stages.

Monday February 06, 2017, 08:05 AM

Prominent Surgeon and Researcher to Lead Multidisciplinary Liver Cancer Initiative

NYU Langone Medical Center

Theodore H. Welling, III, MD, will lead a new state-of-the-art liver cancer program at NYU Langone to advance clinical care and accelerate the translation of lab breakthroughs into superior treatments.

Friday February 03, 2017, 01:05 PM

Cancer Drug Could Double as a Weapon Against Heart Disease, Promoting Regeneration of Damaged Heart Tissue

UT Southwestern Medical Center

An anticancer agent in development promotes regeneration of damaged heart muscle - an unexpected research finding that may help prevent congestive heart failure in the future.

Friday February 03, 2017, 09:45 AM

New Treatment Guides from NCCN Help Patients with Waldenstrom's Macroglobulinemia Make Informed Care Decisions

National Comprehensive Cancer Network(r) (NCCN(r))

NCCN has published the NCCN Guidelines for Patients(r) and NCCN Quick Guide(tm) sheet for Waldenstrom's Macroglobulinemia--a rare, but manageable type of Non-Hodgkin's Lymphoma.

Thursday February 02, 2017, 01:05 PM

Yale Scientists Identify Key Defect in Brain Tumor Cells

Yale Cancer Center

In a new study, Yale Cancer Center researchers identified a novel genetic defect that prevents brain tumor cells from repairing damaged DNA.

Wednesday February 01, 2017, 03:05 PM

Neutrons Identify Critical Details in Bacterial Enzyme Implicated in Gastric Cancer

Oak Ridge National Laboratory

Neutron analysis at the Department of Energy's Oak Ridge National Laboratory is helping researchers better understand a key enzyme found in a bacterium known to cause stomach cancer. Understanding the details of this enzyme, and thus the Helicobacter pylori bacteria's metabolism and biological pathways, could be central to developing drugs that act against H. pylori, but that do not attack the stomach's useful bacteria.

Wednesday February 01, 2017, 12:05 PM

New Radiotracer Could Make Diagnosing Prostate Cancer Faster and Easier

National Institute of Biomedical Imaging and Bioengineering

Researchers at NIBIB have developed a new radiotracer to diagnose prostate cancer and conducted a successful Phase I clinical trial. Prostate cancer is the fifth leading cause of death worldwide and is especially difficult to diagnose. While prostate cancer is relatively easy to treat in its early stages, it is prone to metastasis and can quickly become deadly. In order to plan how aggressively they should treat the cancer, it is important for doctors to know how far the cancer has progressed. NIBIB researchers have attempted to solve this problem by developing a radiotracer that could identify prostate cancer at all stages.

Wednesday February 01, 2017, 10:00 AM

Blood Test That Detects Changes in Tumor DNA Predicts Survival of Women with Advanced Breast Cancer

Johns Hopkins Medicine

Results of a multicenter study of 129 women with advanced breast cancer show that a blood test that spots cancer-linked DNA correctly predicted that most of those patients with higher levels of the tumor markers died significantly earlier than those with lower levels.

Tuesday January 31, 2017, 02:05 PM

Sanford Studying Immunotherapy Drug for Esophageal Cancer

Sanford Health

A clinical trial at Sanford Health is studying if an immunotherapy drug developed by Merck might be able to treat certain patients with advanced esophageal cancer. The Merck Keynote 181 trial is now open at Sanford.

Tuesday January 31, 2017, 11:35 AM

American Thyroid Association Awards Research Grant

American Thyroid Association

The ATA has awarded a 2016 ThyCa Research Grant to Trevor Angell, MD, Instructor in the Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston MA, for his project entitled "Assessment of Circulation Immune Suppressor Cells for Predicating Treatment Response in Follicular Cell Derived Thyroid Carcinoma." The goal of this prospective study is to determine whether changes in the levels of myeloid derived suppressor cells (MDSC) in the peripheral blood of patients with thyroid cancer before and after therapy can serve as a predictive biomarker for response to treatment.

Tuesday January 31, 2017, 09:00 AM

MD Anderson and Guardant Health Announce Partnership to Make Comprehensive Liquid Biopsy Part of Oncology Standard of Care

University of Texas M. D. Anderson Cancer Center

The University of Texas MD Anderson Cancer Center and Guardant Health today announced a multi-year partnership designed to accelerate comprehensive liquid biopsy technology into the standard of care in cancer treatment.

Monday January 30, 2017, 12:05 PM

Clue to How Cancer Cells Spread

Yale Cancer Center

In a second human case, a Yale-led research team has found that a melanoma cell and a white blood cell can fuse to form a hybrid with the ability to metastasize. The finding provides further insight into how melanoma and other cancers spread from solid tumors with implications for future treatment.

Monday January 30, 2017, 11:05 AM

NIH Funds UND Study of Early Formation of Cancer-Causing Viruses

University of North Dakota

Barry Milavetz researches epigenetic modifications in infected cells when they're most easily treatable

Monday January 30, 2017, 11:00 AM

Online Database Aims to Collect, Organize Research on Cancer Mutations

Washington University in St. Louis

Researchers at Washington University School of Medicine in St. Louis have developed an online "knowledgebase" intended for the gathering and organization of cancer genomic information so that clinicians have improved chances of identifying important mutations in a patient's tumor and potentially connecting genetic errors with drugs known to target them. The online resource, called CIViC, is described Jan. 30 in Nature Genetics.

Monday January 30, 2017, 10:00 AM

Stephen Gottschalk, M.D., Has Been Named Chair of the Department of Bone Marrow Transplantation and Cellular Therapy at St. Jude Children's Research Hospital

St. Jude Children's Research Hospital

Esteemed clinician and scientist will oversee one of the world's largest pediatric bone marrow transplantation programs.

Monday January 30, 2017, 08:00 AM

Can Big Data Help Cancer Patients Avoid ER Visits?

Perelman School of Medicine at the University of Pennsylvania

What if doctors could look into a crystal ball and predict which of their patients might be at risk of getting sick enough to go to the emergency room? For at least one group of patients, that's exactly what researchers at Penn Medicine are trying to do.

Friday January 27, 2017, 03:05 PM

Virginia Tech Researchers Help the Body Protect Itself Against Inflammation and Colon Cancer

Virginia Tech

Virginia Tech researchers found that modifying the shape of IRAK-M, a protein that controls inflammation, can significantly reduce the clinical progression of both diseases in pre-clinical animal models.

Friday January 27, 2017, 02:05 PM

Yale Expert to Speak on Turf Safety and Cancer in Soccer Players

Yale Cancer Center

Friday January 27, 2017, 05:00 AM

Artificial Intelligence Uncovers New Insight Into Biophysics of Cancer

Tufts University

For the first time, artificial intelligence has been used to discover the exact interventions needed to obtain a specific, previously unachievable result in vivo, providing new insight into the biophysics of cancer and raising broad implications for biomedicine.

Thursday January 26, 2017, 03:05 PM

Dr. Harold Tara Appointed Medical Director of Smilow Care Centers in Trumbull & Fairfield

Yale Cancer Center

Dr. Harold Tara Appointed Medical Director of Smilow Care Centers in Trumbull & Fairfield

Thursday January 26, 2017, 12:00 PM

Trying to Tango with More Than 2: Extra Centrosomes Promote Tumor Formation in Mice

Johns Hopkins Medicine

When a cell is dividing, two identical structures, called centrosomes, move to opposite sides of the cell to help separate its chromosomes into the new cells.

Thursday January 26, 2017, 11:00 AM

Study Tightens Connection Between Intestinal Microorganisms, Diet, and Colorectal Cancer

Dana-Farber Cancer Institute

Researchers at Dana-Farber Cancer Institute led a study that provides some of the strongest evidence to date that microorganisms living in the large intestine can serve as a link between diet and certain types of colorectal cancer.

Wednesday January 25, 2017, 01:05 PM

Imaging Technique Measures Tumor Stiffness to Aid Surgical Planning

National Institute of Biomedical Imaging and Bioengineering

An important step in planning tumor surgery includes assessing the tumor stiffness to aid in surgical planning. Because tumors within the skull cannot be examined non-invasively, researchers used Magnetic Resonance Elastography (MRE) to assess pituitary tumor stiffness. MRE reliably identified tumors that were soft enough for removal with a minimally-invasive suction technique versus harder tumors requiring more invasive surgery.

Wednesday January 25, 2017, 01:05 PM

New Class of Materials Could Revolutionize Biomedical, Alternative Energy Industries

University of Missouri Health

Polyhedral boranes have become the basis for the creation of cancer therapies, enhanced drug delivery and new contrast agents needed for radioimaging and diagnosis. Now, a researcher at the University of Missouri has discovered an entirely new class of materials based on boranes that might have widespread potential applications, including improved diagnostic tools for cancer and other diseases as well as low-cost solar energy cells.

Wednesday January 25, 2017, 11:05 AM

NIH Honors Research Leaders from University Hospitals, Case Western Reserve University with Prestigious Outstanding Investigator Awards

University Hospitals Cleveland Medical Center

Two internationally recognized research leaders from UH Cleveland Medical Center and Case Western Reserve University School of Medicine have received Outstanding Investigator Awards from the NIH. The 7-year, $6.7 million dollar awards will advance molecular studies of colon cancer and age-related cardiovascular risks.

Wednesday January 25, 2017, 10:00 AM

Murine Study Finds Potential Boost for Ovarian Cancer Drug Olaparib

The Rockefeller University Press

Researchers from the Chinese Academy of Sciences have discovered that the metabolic enzyme phosphoglycerate mutase 1 (PGAM1) helps cancer cells repair their DNA and found that inhibiting PGAM1 sensitizes tumors to the cancer drug Olaparib (Lynparza). Their findings in the study "Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells," which has been published in The Journal of Cell Biology, suggest that this FDA-approved ovarian cancer medicine has the potential to treat a wider range of cancer types than currently indicated.

Wednesday January 25, 2017, 09:00 AM

Orlando Health Takes Proton Therapy to the Next Level with Advanced Image Guidance

Orlando Health

UF Health Cancer Center at Orlando Health is working with Mevion Medical Systems to take the next step in the evolution of the health system's proton therapy center. The organizations are enhancing Orlando Health's proton therapy system with the integration of a mobile, diagnostic computed tomography (CT) scanner.

Tuesday January 24, 2017, 02:05 PM

Yale Expert Discusses Keytruda's Future in Lung Cancer

Yale Cancer Center

Tuesday January 24, 2017, 12:05 PM

New Collaboration Between the University of Kansas Cancer Center and Children's Mercy Hospital Aims to Transform Pediatric Oncology

University of Kansas Cancer Center

The University of Kansas Cancer Center and Children's Mercy Hospital have announced four first-of-their-kind endowed chair appointments that will help eliminate childhood diseases around the world.

Tuesday January 24, 2017, 12:05 PM

IU Study Finds Fly Growth Mimics Cancer Cells, Creating New Tool in Fight Against Disease

Indiana University

Scientists who study a molecule known to play a role in certain types of cancers and neurodegenerative disorders have a powerful new tool to study this compound due to research conducted at Indiana University. The study was published Jan. 23 in the Proceedings of the National Academy of Sciences.

Tuesday January 24, 2017, 12:05 PM

Researchers Discover Potential New Target for Treating Glioblastoma

UT Southwestern Medical Center

Scientists have found a way to inhibit the growth of glioblastoma, a type of brain cancer with low survival rates, by targeting a protein that drives growth of brain tumors, according to research from the Peter O'Donnell Jr. Brain Institute and Harold C. Simmons Comprehensive Cancer Center.

Tuesday January 24, 2017, 12:00 PM

Study Unveils New Way to Starve Tumors to Death

Washington University in St. Louis

Scientists at Washington University School of Medicine in St. Louis have exploited a common weak point in cancer cell metabolism, forcing tumor cells to reveal the backup fuel supply routes they rely on when this weak point is compromised. Mapping these secondary routes, the researchers also identified drugs that block them. They now are planning a small clinical trial in cancer patients to evaluate this treatment strategy.

Tuesday January 24, 2017, 10:05 AM

KU Researchers Find Statins May Hold Keys to Future Cancer Treatment

University of Kansas Cancer Center

Researchers at The University of Kansas Cancer Center have found that high doses of drugs commonly used to fight high cholesterol can destroy a rogue protein produced by a damaged gene that is associated with nearly half of all human cancers

Tuesday January 24, 2017, 10:05 AM

Penn Researchers Help Unravel Mysteries of Pancreatic Cancer's Resistance to Standard Therapies

Perelman School of Medicine at the University of Pennsylvania

In a new study, researchers at the Perelman School of Medicine at the University of Pennsylvania have illuminated one of pancreatic cancer's major resistance mechanisms: a form of inflammation that is triggered by the tumor in response to treatment and helps keep tumor cells alive. Blocking this inflammation after radiation therapy brought a significant improvement in survival in a mouse model of the disease.

Tuesday January 24, 2017, 10:00 AM

Large Pre-ACA Medicaid Expansion Did Not Level Health Disparities in Cancer Surgery

Georgetown University Medical Center

An analysis of the New York State's Medicaid expansion, which predated the 2010 Affordable Care Act, finds substantial decrease in uninsured rate but little change in racial disparities when it comes to access to cancer surgery - a proxy for complex cancer care.

Tuesday January 24, 2017, 09:00 AM

Half of Breast Cancer Patients Experience Severe Side Effects

Michigan Medicine - University of Michigan

Nearly half of women treated for early stage breast cancer reported at least one side effect from their treatment that was severe or very severe, a new study finds.

Monday January 23, 2017, 12:05 PM

Tulane Researchers Find Tumor-Suppressing Protein Actually Promotes Cancer

Tulane University

Tulane University researchers have discovered that the protein PHLDB3, thought to be a potential tumor suppressor, actually allows cancer cells to thrive in pancreatic, prostate, colon, breast, lung, and other common cancers. The discovery could explain how cancer is able to overcome p53 - a key tumor-suppressing protein.

Monday January 23, 2017, 11:00 AM

Research Helps Explain How B Cell Metabolism Is Controlled

Sanford Burnham Prebys Medical Discovery Institute

New research from Sanford Burnham Prebys Medical Discovery Institute (SBP) addresses the lack of knowledge about how B cell metabolism adapts to each of their various environments-- development in the bone marrow, proliferation and hypermutation in the lymph nodes and spleen and circulation in the blood. New findings show that the protein GSK3 acts as a metabolic sensor, or checkpoint, that promotes the survival of circulating B cells while limiting growth and proliferation of B cells in germinal centers.

Monday January 23, 2017, 10:05 AM

A Gene's Journey From Covert to Celebrated

University of North Carolina Health Care System

Unmasking a previously misunderstood gene, Gpr182, University of North Carolina scientists discover an unlikely potential drug target for gastrointestinal cancers.

Friday January 20, 2017, 12:05 PM

CIRM Approves New Funding to UC San Diego Researchers Fighting Zika Virus and Cancer

University of California San Diego Health Sciences

The Independent Citizens Oversight Committee of the California Institute for Regenerative Medicine (CIRM) has approved a pair of $2 million awards to University of California San Diego School of Medicine researchers to advance studies of new treatments for Zika virus infections and the use of stem cell-derived natural killer (NK) cells to target ovarian cancer and other malignancies.

Friday January 20, 2017, 10:05 AM

Researchers Unlock Mechanism of Drug Resistance in Aggressive Breast Cancer

University of North Carolina Health Care System

In the journal Cancer Discovery, UNC Lineberger Comprehensive Cancer Center researchers and colleagues report findings of how triple negative breast cancer cells are able to bypass treatment with trametinib, a U.S. Food and Drug Administration-approved drug that belongs to a class of commonly used anti-cancer drugs called kinase inhibitors. The researchers also reported findings from laboratory models of breast cancer testing a potential treatment approach that could prevent the onset of resistance.

Thursday January 19, 2017, 03:05 PM

Molecular Subgroups of Non-Small Cell Lung Cancer Predict Tumor Behavior, Reveal Treatment Targets

Sbarro Health Research Organization (SHRO)

EGFR mutations is associated with a longer median overall survival (almost double) compared with those without EGFR mutations when treated with specific targeted agents.

Thursday January 19, 2017, 02:05 PM

Breast Cancer Prognosis of African-American Patients May Improve with Administration of Chemotherapy Before Surgery, Study Finds

Georgia State University

Administering chemotherapy to African-American breast cancer patients prior to surgery could improve their prognosis and survival rates from the disease, according to a new study.

Thursday January 19, 2017, 02:05 PM

Brain Tumor Survivor Moves Into Next Phase of Life Thanks to Rehab Experts

Harris Health System

Physical therapist Jorge Neira is helping Ruben Arellano regain use of his arms and the ability to walk. Arellano had a baseball-sized tumor removed from his head. The two share successes and setbacks on the arduous road to recovery at Harris Health System's CARF-accredited hospital.