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Thursday March 30, 2017, 09:00 AM

ASU appoints Josh LaBaer, M.D., Ph.D., as New Biodesign Institute Executive Director

Arizona State University (ASU)

Arizona State University announced today that Joshua LaBaer, M.D., Ph.D., a leading researcher in cancer and personalized medicine, has been appointed the new executive director of the Biodesign Institute at Arizona State University, effective April 1, 2017.

Wednesday March 29, 2017, 02:30 PM

NCCN Annual Conference Sheds Light on Treatment Disparities, Significance of the Doctor-Patient Relationship, Supportive Care Issues, and the Latest Guidelines Updates

National Comprehensive Cancer Network(r) (NCCN(r))

More than 1,600 oncology professionals attended the NCCN 22nd Annual Conference in Orlando, Florida

Wednesday March 29, 2017, 01:05 PM

Call for Entries for ASTRO's 15th Annual Survivor Circle Award

American Society for Radiation Oncology (ASTRO)

The American Society for Radiation Oncology (ASTRO) encourages cancer survivors in or around San Diego to apply for its Survivor Circle Award, an annual honor that recognizes an individual for translating their diagnosis into a commitment to helping others through cancer-related volunteering and service.

Wednesday March 29, 2017, 11:05 AM

Immunologic Changes Point to Potential for Clinical Investigation of Combination Immunotherapy for Deadly Kidney Cancer

University of Texas M. D. Anderson Cancer Center

Immunologic changes observed in an early study of patients with metastatic renal cell carcinoma (MRCC) raised the possibility for a larger clinical study of combination immunotherapy, according to findings reported by researchers at The University of Texas MD Anderson Cancer Center.

Wednesday March 29, 2017, 10:00 AM

Patient, Provider, Caregiver: Physicians Share Lessons Learned When the Tables Are Turned

National Comprehensive Cancer Network(r) (NCCN(r))

In the first time addressing a public forum together, Kalanithi's widow, Lucy Kalanithi, MD, Clinical Assistant Professor of Medicine at Stanford School of Medicine; and Paul's treating oncologist, Heather Wakelee, MD, Associate Professor of Medicine at Stanford Cancer Institute, spoke about their experiences on March 24, 2017 during the National Comprehensive Cancer Network(r) (NCCN(r)) 22nd Annual Conference: Improving the Quality, Effectiveness, and Efficiency of Cancer Care(tm).

Wednesday March 29, 2017, 09:05 AM

Penn Studies Find Promise for Innovations in Liquid Biopsies

Perelman School of Medicine at the University of Pennsylvania

From using fluid in the lungs to better understand the potential of immunotherapy treatments in lung cancer, to tracking circulating tumor cells in prostate cancer, to conducting RNA sequencing of cancer cell clusters from the blood of pancreatic cancer patients, to finding new ways to biopsy tissue from patients who may have esophageal cancer, a series of studies from the Perelman School of Medicine at the University of Pennsylvania demonstrate the promise of new diagnostic methods.

Tuesday March 28, 2017, 06:00 PM

David Livingston, MD, of Dana-Farber, Wins Major Cancer Research Award

Dana-Farber Cancer Institute

David M. Livingston, MD, of Dana-Farber Cancer Institute, has won a major award for discoveries in cancer research from the American Association for Cancer Research (AACR).

Tuesday March 28, 2017, 05:45 PM

Judy Garber, MD, MPH, of Dana-Farber, Wins AACR Award for Outstanding Clinical Research Achievement

Dana-Farber Cancer Institute

Judy E. Garber, MD, MPH, director of the Center for Cancer Genetics and Prevention at Dana-Farber Cancer Institute, has been honored by the American Association for Cancer Research (AACR) for outstanding achievement in clinical cancer research.

Tuesday March 28, 2017, 02:30 PM

Panelists Urge Attendees to Break Down Silos and Address Biases in Cancer Care

National Comprehensive Cancer Network(r) (NCCN(r))

NCCN Conference Roundtable Addresses Health Disparities

Tuesday March 28, 2017, 01:05 PM

Fluorescent Probe Could Light Up Cancer

Michigan Technological University

A fluorescent probe developed by Michigan Tech chemist Haiying Liu lights up the enzyme beta-galactosidase in a cell culture. The glowing probe-enzyme combination could make tumors fluoresce, allowing surgeons to cut away cancer while leaving healthy tissue intact.

Tuesday March 28, 2017, 12:00 PM

NCCN Foundation Awards Grants to Four Young Investigators

National Comprehensive Cancer Network(r) (NCCN(r))

NCCN Foundation Young Investigator Awards provide grants of $150,000 over a two-year period for research initiatives focused on assessing and improving outcomes in cancer care.

Tuesday March 28, 2017, 11:05 AM

"Substantial" Room for Improvement in HPV Vaccination Coverage, Study Finds

Yale Cancer Center

While an HPV vaccine became available over 10 years ago, a study led by the Yale School of Public Health finds that there is "substantial" room for improvement in the way it is recommended and discussed.

Tuesday March 28, 2017, 11:05 AM

Protein Identified as Potential Druggable Target for Pancreatic Cancer

University of Texas M. D. Anderson Cancer Center

A protein known as arginine methyltransferase 1 (PRMT1) may be a potential therapeutic target for pancreatic ductal adenocarcinoma (PDAC), the most common type of pancreatic cancer, and one of the most deadliest with a less than 10 percent, five-year survival rate. PRMT1 is involved in a number of genetic processes including gene transcription, DNA repair and signaling.

Monday March 27, 2017, 07:05 PM

UT Southwestern First in Texas to Premiere Latest Gamma Knife Icon Technology

UT Southwestern Medical Center

Patsy Whittenberg made the six-hour drive from the Texas Panhandle to UT Southwestern Medical Center in Dallas to take advantage of a first for Texas -the latest in Gamma Knife surgery ­that better protects surrounding brain tissue and offers greater comfort without the need for head restraints.

Monday March 27, 2017, 02:05 PM

NIH Grant Will Further Investigation of Breast Tumor Margin Assessment

University of Arkansas, Fayetteville

The National Institutes of Health has awarded a three-year, $424,081 grant to Magda El-Shenawee, electrical engineering professor, for her work on an intraoperative and rapid method of detecting positive cancer margins during conservative breast cancer surgery, or lumpectomy.

Monday March 27, 2017, 01:05 PM

Minority Colorectal Cancer Patients Report Higher Burden of Poor Quality-of-Life Than Whites

University of Texas M. D. Anderson Cancer Center

A study of racial disparities in health-related quality of life of colorectal cancer patients revealed among several findings, that Hispanics and blacks had a higher burden of poor health-related quality-of-life (HR-QoL) than white patients and that poor HR-QoL resulted in shorter median survival. Yet Hispanics had an average survival time of 85.4 months as compared to blacks at 47.8 months and whites at 43.2 months.

Monday March 27, 2017, 12:05 PM

From the Room Next Door to the Next Planet Over

Perelman School of Medicine at the University of Pennsylvania

The new Albert Chadwick Research Room inside the Roberts Proton Therapy Center is no ordinary laboratory space. In fact, there's nothing else quite like it anywhere else in the United States, and whether it's treating patients with cancer or helping NASA with its plans to send astronauts to Mars, the discoveries that could propel scientists forward will happen right here.

Monday March 27, 2017, 12:00 PM

Study Provides Path for New Immunotherapy Approaches to Prostate Cancer

University of Texas M. D. Anderson Cancer Center

Prostate cancer, notoriously resistant to immunotherapy due to its immunologically cool nature, triggers two pathways to chill an immune attack after one immunotherapy drug fires up the immune system, researchers at The University of Texas MD Anderson Cancer Center report in Nature Medicine.

Monday March 27, 2017, 12:00 PM

How Randomness Helps Cancer Cells Thrive

Johns Hopkins Medicine

In a research effort that merged genetics, physics and information theory, a team at the Schools of Medicine and Engineering at Johns Hopkins University has added significantly to evidence that large regions of the human genome have built-in variability in reversible epigenetic modifications made to their DNA

Monday March 27, 2017, 10:00 AM

Researchers Warn of Hazards of Smoking and Need for Wider Use of Varenicline to Quit

Florida Atlantic University

More than 35 million Americans are trying to quit smoking. Experts reassure clinicians and their patients that varenicline, whose brand name is Chantix, is a safe and effective way to achieve smoking cessation and that failure to use this drug has caused preventable heart attacks and deaths from cardiovascular disease. Just a few months ago, the FDA removed the black box warning from varenicline.

Friday March 24, 2017, 05:05 PM

Immunotherapy Drug Becomes First Therapy Approved by FDA for Rare Skin Cancer

Fred Hutchinson Cancer Research Center

The U.S. Food and Drug Administration yesterday granted accelerated approval to the checkpoint inhibitor Bavencio (avelumab) for the treatment of patients with metastatic Merkel cell carcinoma. Dr. Paul Nghiem, a senior investigator on the clinical trial that led to yesterday's fast-track FDA approval and an expert on MCC is available for interviews, as is a patient who participated in the clinical trial.

Friday March 24, 2017, 02:30 PM

NCCN Foundation Board Names New Leadership

National Comprehensive Cancer Network(r) (NCCN(r))

Gena Cook, Co-Founder and Chief Executive Officer, Navigating Cancer, and Heather Kopecky, PhD, MBA, Senior Client Partner, Korn Ferry, have been named Chair and Vice-Chair, respectively, of the NCCN Foundation Board of Directors.

Friday March 24, 2017, 01:05 PM

Colorectal Cancer Rates Up Among Young Adults; What You Should Know

University of California, Los Angeles (UCLA), Health Sciences

Researchers predict that 13,500 new cases of colon and rectal cancers will be diagnosed in Americans under age 50 this year; in all age groups, about 100,000 cases of colon cancer and nearly 40,000 cases of rectal cancer are expected.

Friday March 24, 2017, 11:05 AM

Colon Cancer: Early Detection Can Save Your Life

Valley Health System

Colorectal cancer is the second leading cause of cancer death for men and women in the United States according to the American Cancer Society (ACS). In fact, the ACS estimates that 134,490 people in the United States were diagnosed with colorectal cancer in 2016, including 70,820 men and 63,670 women. In addition, the ACS estimates that 49,190 people, 26,020 men and 23,170 women, died from colorectal cancer in 2016.

Thursday March 23, 2017, 04:05 PM

Hitting Cancer with High-Intensity Ultrasound and Immunotherapy

UC Davis Comprehensive Cancer Center

In a new study published today in JCI Insight, UC Davis researchers have shown that combining high-intensity focused ultrasound with two immunotherapies (a PD-1 checkpoint inhibitor and TLR9 agonist) can produce excellent response rates in mouse models of epithelial cancer. They also found that, for the combination to be effective, immunotherapies must come first.

Thursday March 23, 2017, 04:00 PM

Keck School of Medicine of USC Receives Grant to Fund Research on the Link Between Gastroesophageal Reflux Disease and Esophageal Cancer

Keck Medicine of USC

The Keck School of Medicine of the University of Southern California (USC) has received a grant to fund research on the link between gastroesophageal reflux disease and esophageal cancer.

Thursday March 23, 2017, 01:00 PM

A New Approach to Target an 'Undruggable' Prostate Cancer Driver

Michigan Medicine - University of Michigan

When small-molecule inhibitors proved elusive, researchers developed a novel strategy: Using large molecule peptides to target a common prostate cancer driver. It may provide a path for developing new therapies against a challenging target.

Thursday March 23, 2017, 12:00 PM

Preterm Births More Common in Mothers Who Are Cancer Survivors

University of North Carolina Health Care System

In a study published in the journal JAMA Oncology, UNC Lineberger Comprehensive Cancer Center researchers report that women diagnosed and treated for cancer during their childbearing years more commonly gave birth prematurely, and to babies whose weights were below normal ranges. Cancer survivors also had a slightly higher rate of cesarean section deliveries.

Thursday March 23, 2017, 10:45 AM

UVA Discovers ANOTHER Immune System Link Science Said Didn't Exist

University of Virginia Health System

UVA researchers have again shown that a part of the body thought to be disconnected from the immune system actually interacts with it, and that discovery helps explain cases of male infertility, certain autoimmune diseases and even the failure of cancer vaccines.

Thursday March 23, 2017, 10:00 AM

A New Approach to Diagnosing Mental Disorders Could Become an Alternative to DSM-5

Stony Brook University

A consortium of psychiatrists and psychologists from universities worldwide, co-led by Stony Brook University, University of Minnesota and University of Notre Dame, has proposed a new approach to diagnosing mental disorders.

Wednesday March 22, 2017, 11:05 AM

'First in Human' Trial Defines Safe Dosage for Small Molecule Drug ONC201 for Solid Cancer Tumors

Rutgers Cancer Institute of New Jersey

A 'first in human' clinical trial examining the small molecule drug ONC201 in cancer patients with advanced solid tumors shows that this investigational drug is well tolerated at the recommended phase II dose. That's according to Rutgers Cancer Institute of New Jersey investigators whose research also showed early signs of clinical benefit in patients with advanced prostate and endometrial cancers.

Wednesday March 22, 2017, 01:00 AM

Lynch Syndrome Awareness Day Brings Attention to Hereditary Colorectal Cancer Syndromes

American College of Gastroenterology (ACG)

Cancer prevention advocates and researchers have designated March 22nd as National Lynch Syndrome Awareness Day. Carol A. Burke, MD, FACG, President of the American College of Gastroenterology (ACG), a gastroenterologist specializing in hereditary colorectal cancer syndromes at the Cleveland Clinic in Cleveland, OH, today offered commentary and guidance for GI physicians on Lynch Syndrome in an ACG communication to her colleagues.

Tuesday March 21, 2017, 12:00 PM

New Insights Into Side Effects Can Help Prostate Cancer Patients Choose Treatments

University of North Carolina Health Care System

A new study led by UNC Lineberger Comprehensive Cancer Center researchers identifies distinct patterns of side effects for prostate cancer treatments that patients could use to guide their choices.

Tuesday March 21, 2017, 11:45 AM

Available Now: New Toolkit Encourages Better Communication to Help Prevent Patients from Suffering in Silence Due to Chemotherapy-induced Nausea and Vomiting

Hematology Oncology Pharmacy Association

The Hematology/Oncology Pharmacy Association (HOPA), in partnership with Eisai Inc. and Helsinn Therapeutics (U.S.), Inc., today announced the launch of the Time to Talk CINV(tm) toolkit, which is comprised of resources for patients with cancer going through chemotherapy and their healthcare providers.

Tuesday March 21, 2017, 11:05 AM

Racial Disparities in Genetic Testing of Women with Breast Cancer

Yale Cancer Center

Tuesday March 21, 2017, 11:05 AM

Tanning Dependence Linked to Other Addictive Behaviors, New Study Finds

Yale Cancer Center

Despite the known dangers of exposure to ultraviolet light, many people continue to sunbathe and use indoor tanning beds with some users exhibiting a dependence to tanning. A new study from the Yale School of Public Health finds that such dependence is also associated with other addictive behaviors.

Tuesday March 21, 2017, 10:00 AM

Producing Radioisotopes for Medical Imaging and Disease Treatment

Brookhaven National Laboratory

Accelerators built to explore the building blocks of matter help to feed the nation's need for certain critical radioisotopes used to diagnose, track, and treat disease.

Tuesday March 21, 2017, 09:05 AM

Direct Tumor Vaccination Shown to Induce Anti-Tumor Immunity and Increase Survival in a Murine Model of Pancreatic Cancer

Rutgers Cancer Institute of New Jersey

Building on their previous research focusing on vaccination within a tumor (intratumoral) for the most common form of pancreatic cancer, investigators from Rutgers Cancer Institute of New Jersey and Rutgers Robert Wood Johnson Medical School have shown that in a mouse model of early stage resected pancreatic cancer, intratumoral vaccination induces an anti-tumor response that results in a significant improvement in overall survival.

Tuesday March 21, 2017, 09:05 AM

New Research Findings: Health Costs for Children with Cancer Are Higher Than for Adolescents, Adults

International Society for Pharmacoeconomics and Outcomes Research (ISPOR)

ISPOR announced the publication of original research estimating the costs of cancer care in children and adolescents in the March issue of Value in Health.

Monday March 20, 2017, 01:05 PM

Gene Editing Technique Helps Find Cancer's Weak Spots

University of California San Diego Health Sciences

Genetic mutations that cause cancer also weaken cancer cells, allowing researchers to develop drugs that will selectively kill them. This is called "synthetic lethality" because the drug is only lethal to mutated (synthetic) cells. Researchers at UC San Diego School of Medicine and Jacobs School of Engineering developed a method to search for synthetic-lethal gene combinations. The technique, published March 20 in Nature Methods, uncovered 120 new opportunities for cancer drug development.

Monday March 20, 2017, 01:00 PM

Scientists Find Possible Achilles Heel of Treatment Resistant Cancers

Cincinnati Children's Hospital Medical Center

Scientists identify two signaling proteins in cancer cells that make them resistant to chemotherapy, and show that blocking the proteins along with chemotherapy eliminate human leukemia in mouse models. Reporting results March 20 in Nature Medicine, researchers at Cincinnati Children's Hospital Medical Center suggest that blocking the signaling proteins c-Fos and Dusp1 as part of combination therapy might cure several types of kinase-driven, treatment-resistant leukemia and solid tumor cancers.

Monday March 20, 2017, 12:05 PM

Researchers Discover Key to Drug Resistance in Common Breast Cancer Treatment

Scripps Research Institute

Scientists from the Florida campus of The Scripps Research Institute (TSRI), the University of California (UC), San Diego and the University of Illinois have found that two immune system molecules may be key to the development of drug resistance in estrogen-driven breast cancers.

Monday March 20, 2017, 12:00 PM

Sanford Burnham Prebys Scientist Joins Forces with Rady Children's for Genomic Medicine to Fight Childhood Brain Cancer

Sanford Burnham Prebys Medical Discovery Institute

Rady Children's Institute for Genomic Medicine (RCIGM) announced that Robert Wechsler-Reya, Ph.D., has been named program director for the Joseph Clayes III Research Center for Neuro-Oncology and Genomics at RCIGM. Wechsler-Reya, a professor at Sanford Burnham Prebys Medical Discovery Institute (SBP), will retain his position as director of the Tumor Initiation and Maintenance Program at SBP's NCI-designated Cancer Center and will hold a joint appointment at RCIGM.

Friday March 17, 2017, 05:00 PM

Automatic Palliative Care Consult for Patients with Advanced Cancers Leads to Improved Outcomes

Yale Cancer Center

A recent study demonstrated that increased palliative care consultations for patients with advanced cancers is associated with substantial impact on 30-day readmission, administration of chemotherapy following discharge, hospice referral, and use of support services following discharge.

Thursday March 16, 2017, 05:15 PM

Health Experts Available to Discuss President Trump's Proposed NIH Budget Cuts

West Virginia University

Thursday March 16, 2017, 05:05 PM

Fat Cells Step in to Help Liver During Fasting

UT Southwestern Medical Center

How do mammals keep two biologically crucial metabolites in balance during times when they are feeding, sleeping, and fasting? The answer may require rewriting some textbooks.

Thursday March 16, 2017, 04:05 PM

Yale Study Published in JNCCN Uncovers Racial Disparities in Treatment of Women with Breast Cancer

Yale Cancer Center

The study, "Racial and Ethnic Disparities in Oncotype Dx(tm) Test Receipt in a State-Wide Population-Based Study," led by Cary P. Gross, MD, Yale University School of Medicine and a member of Yale Cancer Center, is published in the March issue of JNCCN - Journal of the National Comprehensive Cancer Network.

Thursday March 16, 2017, 03:05 PM

Updated Data on SBRT Radiation for NSCLC Lung Cancer Confirm Benefits of 'One and Done' Approach

Roswell Park Cancer Institute

Collaborative study with Cleveland Clinic & SUNY Upstate Medical University shows that single high-dose SBRT treatment is as effective as three doses in patients with non-small cell lung cancer

Thursday March 16, 2017, 03:05 PM

Scripps Florida Scientists Develop New Drug Delivery Method for Cancer Therapy

Scripps Research Institute

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have developed a new drug delivery method that produces strong results in treating cancers in animal models, including some hard-to-treat solid and liquid tumors.

Thursday March 16, 2017, 03:05 PM

Bioinformatics Computer Model Predicts Deadliest Lung Cancers

UT Southwestern Medical Center

After evaluating more than 900 differences in the shape and structure of cancer cells, UT Southwestern Medical Center researchers developed a computer model able to predict the most deadly lung cancers based on a fraction of those features.

Thursday March 16, 2017, 12:00 PM

Racial Disparities Persist in Treatment and Survival of Early Stage Lung Cancer

American Society for Radiation Oncology (ASTRO)

Analysis of the largest American cancer database indicates that racial disparities persist in the treatment and outcomes of patients diagnosed with stage I non-small cell lung cancer (NSCLC).

Thursday March 16, 2017, 12:00 PM

Genetic Profile of Treatment-Resistant Lung Cancer More Variable Than Previously Understood

American Society for Radiation Oncology (ASTRO)

The genetic mutations underlying treatment resistance in non-small cell lung cancer (NSCLC) are more complex and dynamic than previously thought.

Thursday March 16, 2017, 12:00 PM

Proton Therapy Offers New Treatment Possibility for Recurrent Lung Cancer

American Society for Radiation Oncology (ASTRO)

A new study offers hope for patients with recurrent lung cancer, who historically have been considered ineligible for curative treatment.

Thursday March 16, 2017, 12:00 PM

SBRT Offers Curative Option for Lung Cancer Patients Age 80 and Older

American Society for Radiation Oncology (ASTRO)

Patients in their 80s and 90s who have early stage lung cancer but cannot undergo an operation can be treated safely and effectively with stereotactic body radiation therapy (SBRT), according to research presented today at the 2017 Multidisciplinary Thoracic Cancers Symposium.

Thursday March 16, 2017, 12:00 PM

Biomarker Blood Test Shows Cancer Recurrence Months Before CT Scans

American Society for Radiation Oncology (ASTRO)

Results from a prospective clinical trial showed that a blood test looking at specific biomarkers was able to detect recurrences of lung cancer an average of six months before conventional imaging methods found evidence of recurrence.

Thursday March 16, 2017, 12:00 PM

Combination of Radiation and Immune Checkpoint Therapy Holds Potential for Lung Cancer

American Society for Radiation Oncology (ASTRO)

An emerging approach for cancer treatment seeks to combine radiation therapy with immune checkpoint inhibitors (ICPIs) to more effectively control tumors in the chest with an acceptable risk of severe treatment-related side effects.

Thursday March 16, 2017, 10:00 AM

New Supportive Care Resources from NCCN Help Patients with Cancer Confront Distress

National Comprehensive Cancer Network(r) (NCCN(r))

New NCCN Guidelines for Patients(r): Distress available on NCCN.org/patients

Wednesday March 15, 2017, 03:00 PM

New Driver, Target in Advanced Mucosal Melanoma

University of Colorado Cancer Center

A University of Colorado Cancer Center study published March 15, 2017 in the journal Melanoma Research uses the unique resource of over 600 melanoma samples collected at the university to demonstrate, for the first time, novel mutations involved in mucosal melanoma, paving the way for therapies to treat this overlooked subtype.

Wednesday March 15, 2017, 02:30 PM

Yale Study Published in JNCCN Uncovers Racial Disparities in Treatment of Women with Breast Cancer

National Comprehensive Cancer Network(r) (NCCN(r))

Researchers at Yale Cancer Center/Smilow Cancer Hospital found that black and Hispanic women in Connecticut are significantly less likely to undergo gene expression profiling than white women.

Wednesday March 15, 2017, 02:05 PM

New Liver Cancer Program Launches at Smilow Cancer Hospital

Yale Cancer Center

In the last 10 years there has been a constant growth in the number of patient with primary liver cancer treated at Yale New Haven Hospital and at Smilow Cancer Hospital. Smilow is one of the few medical center able to offer to patients with primary liver cancer a comprehensive array of therapeutic approaches and personalized care, according to the needs of each patient. These considerations have justified the formation of a freestanding Liver Cancer Program.

Wednesday March 15, 2017, 01:05 PM

New Alternative to Colonoscopy Is as Easy as Swallowing a Pill

Loyola University Health System

The patient ingests a capsule containing two miniature cameras on either end. As the capsule travels through the digestive tract, it captures images and wirelessly transmits them to a recorder the patient wears on a belt.

Tuesday March 14, 2017, 12:05 PM

Drug Combination Delivered by Nanoparticles May Help in Melanoma Treatment

Penn State College of Medicine

The first of a new class of medication that delivers a combination of drugs by nanoparticle may keep melanoma from becoming resistant to treatment, according to Penn State College of Medicine researchers.

Tuesday March 14, 2017, 11:20 AM

The Molecular Underpinnings of T Cell Exhaustion

La Jolla Institute for Allergy and Immunology

One reason we survive into adulthood is that cell-killing T cells usually recognize and eliminate cancerous or pathogen-infected cells. But prolonged overactivity of immune cells summoned to a tumor or infection site can render them useless to dispatch invaders, a cellular state immunologists call "exhaustion." Fortunately, cancer researchers are devising effective immunotherapies to counter exhaustion and re-motivate immune cells to eradicate a patient's tumor

Monday March 13, 2017, 04:05 PM

Congressman Donald M. Payne, Jr., Visits Rutgers Cancer Institute at University Hospital

Rutgers Cancer Institute of New Jersey

Highlighting progress and promise in cancer research, including advances made in colorectal cancer, representatives from Rutgers Cancer Institute of New Jersey, American Association of Cancer Research, and University Hospital recently met with Congressman Donald M. Payne, Jr., at Rutgers Cancer Institute of New Jersey at University Hospital in Newark.

Friday March 10, 2017, 03:05 PM

Castration-Resistant Prostate Cancer Cell Growth Impeded by Endostatin

University of Alabama at Birmingham

Endostatin, a naturally occurring protein in humans, can significantly decrease proliferation of castration-resistant prostate cells in culture, and researchers describe the physiological pathways and signaling evoked by endostatin.

Friday March 10, 2017, 12:05 PM

Targeting Cancer Stem Cells Improves Treatment Effectiveness and Prevents Metastasis

University of California, Los Angeles (UCLA), Health Sciences

Targeting cancer stem cells may be a more effective way to overcome cancer resistance and prevent the spread of squamous cell carcinoma -- the most common head and neck cancer and the second-most common skin cancer, according to a new study by cancer researchers at the UCLA School of Dentistry. Head and neck squamous cell carcinoma is a highly invasive form of cancer and frequently spreads to the cervical lymph nodes.

Thursday March 09, 2017, 02:05 PM

Look Twice, Cut Once

University of California San Diego Health Sciences

Larry Smarr needed surgery. His surgeon performed the procedure twice: the first time on his virtual self. A look at the possible future of surgery.

Thursday March 09, 2017, 01:05 PM

Potential Drug Candidates Halt Prostate and Breast Cancer Growth

Scripps Research Institute

Scientists on the Florida campus of The Scripps Research Institute (TSRI) have designed two new drug candidates to target prostate and triple negative breast cancers.

Thursday March 09, 2017, 10:05 AM

Discovery of a New Metabolic Pathway of a Known Lipid Has Implications in Cancer, Obesity

Stony Brook University

A collaborative Stony Brook University research team has discovered a novel metabolic pathway of the lipid ceramide, which is involved in cell death.

Thursday March 09, 2017, 09:00 AM

Personalized Medicine, Proton Therapy and More Advances in Lung Cancer Research to Be Featured at Symposium Next Week

American Society for Radiation Oncology (ASTRO)

The press program for next week's 2017 Multidisciplinary Thoracic Cancers Symposium features research advances in lung cancer including immunotherapy, proton therapy and liquid biopsy, among others.

Wednesday March 08, 2017, 04:05 PM

Hackensack Meridian Health Now the Only Provider to Offer Advanced Technology to Target Breast Tumors in Monmouth and Ocean Counties

Meridian Health

Surgeons and radiologists at four hospitals in coastal New Jersey are among an elite few to use the SAVI SCOUT(r) surgical guidance system.

Wednesday March 08, 2017, 01:05 PM

Preventing Cancer in Latinos, One Text Message at a Time

University of Kansas Cancer Center

Latinos experience significant disparities in health care including higher rates of particular cancers, lower cancer screening rates and cancer diagnoses at more advanced stages. Researchers at The University of Kansas Cancer Center want to help Latinos with tobacco cessation treatment (both medication and behavioral support) via text messaging.

Wednesday March 08, 2017, 01:05 PM

In Battle for Real Estate, a Disordered Protein Wins Out

Scripps Research Institute

New TSRI Study Points to Potential Strategy to Kill Cancer Cells

Wednesday March 08, 2017, 01:00 PM

Novel Compound That Engages 'Second Arm' of Immune System Reduces Breast Tumors and Metastases, Study Shows

Dana-Farber Cancer Institute

In a new study in the journal Nature, Dana-Farber Cancer Institute scientists report that a compound able to reverse the allegiance of innate immune system cells - turning them from tumor enablers into tumor opponents - caused breast tumors in mice to shrink and withdraw from distant metastases.

Wednesday March 08, 2017, 11:05 AM

Women More Likely to Follow Through with Breast Screening Recommendations When Informed Directly

University of Colorado Cancer Center

Women at high risk for breast cancer who received a letter informing them of their options for additional imaging with contrast-enhanced MRI of the breast (in addition to a letter sent to their primary care physician) were more likely to return to the center for additional screening with MRI.

Wednesday March 08, 2017, 09:05 AM

Tackling Some of the Basic Building Blocks of Cancer

Rutgers Cancer Institute of New Jersey

Research by Rutgers University investigators - including a number from Rutgers Cancer Institute of New Jersey - has resulted in the development of small molecule inhibitors that block a protein involved in the development of some cancers. At focus are TAM receptors, which when overexpressed can make too many proteins leading to cancer development, drug resistance and overall poor patient survival.

Tuesday March 07, 2017, 05:05 PM

$1.1 Million Grant Funds Study on Why Early Pregnancy Prevents Breast Cancer

Texas Tech University Health Sciences Center El Paso

EL PASO, Texas - Biomedical scientist Rajkumar Lakshmanaswamy, Ph.D., has received a $1.1 million research grant from the U.S. Department of Defense (DOD) to study how early pregnancy reduces a woman's risk for breast cancer.

Tuesday March 07, 2017, 04:30 PM

Early Deaths From Childhood Cancer Up to 4 Times More Common Than Previously Reported

University of Colorado Cancer Center

Treatments for childhood cancers have improved to the point that 5-year survival rates are over 80 percent. However, one group has failed to benefit from these improvements, namely children who die so soon after diagnosis that they are not able to receive treatment, or who receive treatment so late in the course of their disease that it is destined to fail.

Tuesday March 07, 2017, 04:05 PM

$1.5 Million to Prevent Cervical Cancer in West Texas

Texas Tech University Health Sciences Center El Paso

EL PASO, Texas - Navkiran Shokar, M.A., M.P.H, M.D., has received nearly $1.5 million from the Cancer Prevention and Research Institute of Texas (CPRIT) to reduce the burden of cervical cancer in West Texas.

Tuesday March 07, 2017, 03:05 PM

Lung Cancer May Go Undetected in Kidney Cancer Patients

UT Southwestern Medical Center

Could lung cancer be hiding in kidney cancer patients? Researchers with the Harold C. Simmons Comprehensive Cancer Center's Kidney Cancer Program studied patients with metastatic kidney cancer to the lungs and found that 3.5 percent of the group had a primary lung cancer tumor that had gone undiagnosed. This distinction can affect treatment choices and rates of survival.

Tuesday March 07, 2017, 02:00 PM

UCLA Scientists Show How to Amplify or Stifle Signals for Immune Responses

University of California, Los Angeles (UCLA), Health Sciences

UCLA scientists pioneered an approach to observe in real time what excites T cells at the nanoscale, pinpointed the pathway that controls immune response and identified drugs that could equip scientists with the ability to manipulate the immune system and control disease.

Tuesday March 07, 2017, 01:00 PM

Economic Disparities a Growing Concern for Cancer Diagnosis and Treatment

Sbarro Health Research Organization (SHRO)

The most recent global cancer data from the WHO highlights the growing differences in mortality rate among regions of the world bearing very different economic circumstances.

Tuesday March 07, 2017, 12:05 PM

Promising New Strategy to Attack the Most Lethal Brain Tumor in Children

Ann & Robert H. Lurie Children's Hospital of Chicago

Researchers from Northwestern Medicine and Ann & Robert H. Lurie Children's Hospital of Chicago have revealed new insight into how the most deadly pediatric brain tumor, diffuse intrinsic pontine glioma (DIPG), may develop. They also have identified a compound that targets the "on" switch for cancer-promoting genes, which resulted in shrinking tumor size and increased survival in an animal model of DIPG. Preparations for a clinical trial at Lurie Children's are now under way.

Tuesday March 07, 2017, 09:05 AM

Diabetes Drug May Be Effective Against Deadly Form of Breast Cancer, Study Suggests

The Rockefeller University Press

Researchers in China have discovered that a metabolic enzyme called AKR1B1 drives an aggressive type of breast cancer. The study, "AKR1B1 promotes basal-like breast cancer progression by a positive feedback loop that activates the EMT program," which has been published in The Journal of Experimental Medicine, suggests that an inhibitor of this enzyme currently used to treat diabetes patients could be an effective therapy for this frequently deadly form of cancer.

Monday March 06, 2017, 05:05 PM

Cancer 'Hot Spots' in Florida May Be Associated with Hazardous Waste Sites

University of Missouri Health

Studies have shown that hazardous waste sites have the potential to adversely affect human health and disrupt ecological systems. Florida has the sixth highest number of hazardous waste sites, known as Superfund sites, in the United States. In 2016, the state was projected to have the second largest number of new cancer cases in the country. Researchers from the University of Missouri School of Medicine and the University of Florida studied cancer incidence rates in relation to Superfund sites and found a possible association. Researchers believe this discovery could help direct public health efforts in the state.

Monday March 06, 2017, 03:30 PM

NCCN Conference to Address End-of-Life Psychosocial Needs, Latest Oncology Treatment Advances, and Guidelines Updates

National Comprehensive Cancer Network(r) (NCCN(r))

22nd Annual Conference is March 23-25, 2017, in Orlando, FL

Friday March 03, 2017, 10:00 AM

Functional Brain Training Alleviates Chemotherapy-Induced Peripheral Nerve Damage in Cancer Survivors

University of Texas M. D. Anderson Cancer Center

A type of functional brain training known as neurofeedback shows promise in reducing symptoms of chemotherapy-induced nerve damage, or neuropathy, in cancer survivors, according to a study by researchers at The University of Texas MD Anderson Cancer Center. The pilot study, published in the journal Cancer, is the largest, to date, to determine the benefits of neurofeedback in cancer survivors.

Thursday March 02, 2017, 02:05 PM

Surviving Prostate Cancer Through Advanced Diagnostics and Robot-Assisted Technology

NYU Lutheran Medical Center

Marc Bjurlin, DO, (right) director of urologic oncology at NYU Lutheran Medical Center, used state-of-the-art technology to help patient Mikhail Kurbesov beat prostate cancer.

Thursday March 02, 2017, 01:05 PM

Caring for the Caregiver

Rutgers Cancer Institute of New Jersey

During cancer treatment, the main focus is on the patient. However, a cancer diagnosis affects the entire family, including caregivers, whose needs often can be overlooked. During this Social Work Month, members of Rutgers Cancer Institute of New Jersey's Social Work Department share some tips on how caregivers can keep their bodies and minds healthy - without breaking the bank or spending a lot of time - in order to provide the best care for the patient.

Thursday March 02, 2017, 01:05 PM

Study Finds Not All Women Get Appropriate Care for Cervical Cancer

Michigan Medicine - University of Michigan

Fewer than three out of five women with cervical cancer received guideline-based care, a new study finds. For black and Hispanic women, it's just over half, which could help explain why cervical cancer outcomes tend to be worse for these women.

Thursday March 02, 2017, 09:05 AM

The Medical Minute: Are You at Increased Risk for Colorectal Cancer?

Penn State Health Milton S. Hershey Medical Center

Most people know doctors recommend a colonoscopy at age 50 to screen for colorectal cancers. What they might not know is that earlier screening may be necessary if they have a family history of colorectal cancer or other diseases.

Thursday March 02, 2017, 06:00 AM

Scientists Wage Fight Against Aging Bone Marrow Stem Cell Niche

Cincinnati Children's Hospital Medical Center

As people get older so do the hematopoietic stem cells (HSCs) that form their blood, creating an increased risk for compromised immunity and certain blood cancers. Now researchers are reporting in the scientific journal EMBO that the bone marrow niche where HSC's form also ages, contributing to the problem. In a study published March 2, scientists in Germany and the United States propose rejuvenating the bone marrow niche where HSCs are created.

Wednesday March 01, 2017, 05:00 PM

Monoclonal Antibody Drug Superior to Chemotherapy for Advanced Acute Lymphoblastic Leukemia

University of Texas M. D. Anderson Cancer Center

A Phase III clinical trial involving 101 centers in 21 countries revealed the monoclonal antibody blinatumomab to be more effective than standard chemotherapy for treatment of advanced acute lymphoblastic leukemia (ALL). Study findings were published in the March 1 online issue of the New England Journal of Medicine.

Wednesday March 01, 2017, 03:05 PM

YCC Researcher Craig Crews Is Recipient of Cancer Research Award

Yale Cancer Center

Yale scientist Craig M. Crews is the recipient of the 2017 Outstanding Achievement in Chemistry in Cancer Research Award granted by the American Association of Cancer Research (AACR).

Wednesday March 01, 2017, 03:05 PM

In-House Specialty Pharmacy Reduces Medical Errors, Wait Time

Yale Cancer Center

Dr. Kerin Adelson discusses the in-house specialty pharmacy at Smilow Cancer Hospital with HemeOnc Today

Wednesday March 01, 2017, 03:05 PM

Ovarian Cancer Target Molecule May Be Key to Blocking Its Spread

University of Illinois at Chicago

Blocking a protein found on the surface of ovarian cancer cells could prevent or reduce the spread of the disease to other organs, according to new research at the University of Illinois at Chicago.