RSS Channels Index
Tuesday 21-May-2013
Highlights
> Study Establishes Basis for Genomic Classification of Endometrial CancersComprehensive genomic analysis of nearly 400 endometrial tumors suggests molecular characteristics – such as the frequency of mutations – could complement current pathology methods and help distinguish between principal types of endometrial tumors and provide insights into potential treatment strategies...(read more) 
> TCGA Researchers Identify Potential Drug Targets, Markers for Leukemia RiskInvestigators for The Cancer Genome Atlas (TCGA) Research Network have detailed the genomic alterations underlying the development of acute myeloid leukemia (AML), painting a picture of a cancer marked by relatively few mutations compared to other types of cancer occurring in adults...(read more) 
> NIH Trial Shows Promising Results in Treating a Lymphoma in Young PeoplePatients with mediastinal B-cell lymphoma who received infusions of chemotherapy, but not radiation, had excellent outcomes (...read more) 
Bevacizumab Significantly Improves Survival for > Patients with Recurrent and Metastatic Cervical CancerPatients with advanced, recurrent, or persistent cervical cancer that was not curable with standard treatment who received the drug bevacizumab (Avastin) lived 3.7 months longer than patients who did not receive the drug...read more 
“Bringing Light” to Cancer Patients > Dr. Jim Olson Talks with the NCI about the Tumor Paint Imaging DrugOn a clear evening in Seattle last September, a hundred people gathered silently in the courtyard of Fred Hutchinson Cancer Center. The usually talkative group had just watched “Bringing Light,” a 3-minute documentary about a new drug....read more 
> Three Questions About HPV VaccinationIn 2009, more than 30,000 people in the U.S. learned they had cancer linked to the human papillomavirus, or HPV. This virus is best known for causing cervical cancer, but it’s also the culprit behind many cancers of the mouth, throat, anus, and genitals. Unlike many forms of cancer, for which we lack the knowledge and tools to prevent, scientists have figured out how to dodge HPV-triggered cancers. ...read more 
> NCI 2013 Annual ReportThis annual report provides a look at NCI's proposed budget as well as describes some of the NCI’s broad research programs. It also discusses several specific types of cancers that exemplify the various strategies and the variable rates of progress on the different diseases that we are working to control. ...more 
> Report to the Nation Shows U.S. Cancer Death Rates Continue to DropThe Annual Report to the Nation on the Status of Cancer, 1975–2009, shows that overall cancer death rates continued to decline in the United States among both men and women, among all major racial and ethnic groups, and for all of the most common cancer sites, including lung, colon and rectum, female breast, and prostate. ...more 
> Questions and Answers: Annual Report to the Nation on the Status of CancerQuestions and Answers: Annual Report to the Nation on the Status of Cancer, 1975–2009, Featuring the Burden and Trends in HPV-Associated Cancers and HPV Vaccination Coverage Levels ...more 
> The Living Lab: Navigating Into CellsHow do viruses attach to cells? How do proteins interact and mediate infection? How do molecular machines organize themselves in healthy cells? How do they differ in diseased cells? These are the types of questions National Institutes of Health researchers ask...more Recent ResearchOlder Prostate Cancer Patients with Other Underlying Health Problems Ought to Think Twice Before Getting TreatmentOlder prostate cancer patients with other underlying health conditions should think twice before committing to surgery or radiation therapy for their cancer, according to a multicenter study led by researchers in the UCLA Department of Urology. –University of California, Los Angeles (UCLA), Health Sciences|2013-05-20
IMRT May Not Be More Effective Than Older Radiation Techniques After Prostatectomy
Intensity-modulated radiation therapy has become the most commonly used type of radiation in prostate cancer, but research from the University of North Carolina suggests that the therapy may not be more effective than older, less expensive forms of radiation therapy in patients who have had a prostatectomy. –University of North Carolina School of Medicine|2013-05-20
Two Radiotherapy Treatments Show Similar Morbidity, Cancer Control After ProstatectomyUse of the newer, more expensive intensity-modulated radiotherapy (IMRT) and use of the older conformal radiotherapy (CRT) after surgical removal of all or part of the prostate gland were associated with similar morbidity and cancer control outcomes, according to a study published Online First by JAMA Internal Medicine, a JAMA Network publication. –American Medical Association (AMA)|2013-05-20
Timing of Cancer Radiation Therapy May Minimize Hair Loss, Researchers Say
Discovering that mouse hair has a circadian clock - a 24-hour cycle of growth followed by restorative repair - researchers suspect that hair loss in humans from toxic cancer radiotherapy and chemotherapy might be minimized if these treatments are given late in the day. –Salk Institute for Biological Studies|2013-05-20
The Compound in the Mediterranean Diet that Makes Cancer Cells ‘Mortal’New research suggests that a compound abundant in the Mediterranean diet takes away cancer cells’ “superpower” to escape death. –Ohio State University|2013-05-20
Genetic Diversity Within Tumors Predicts Outcome in Head and Neck CancerA new measure of the heterogeneity – the variety of genetic mutations – of cells within a tumor appears to predict treatment outcomes of patients with the most common type of head and neck cancer. –Massachusetts Eye and Ear Infirmary|2013-05-20
Molecular Marker from Pancreatic ‘Juices’ Helps Identify Pancreatic CancerResearchers at Mayo Clinic have developed a promising method to distinguish between pancreatic cancer and chronic pancreatitis — two disorders that are difficult to tell apart. A molecular marker obtained from pancreatic “juices” can identify almost all cases of pancreatic cancer, their study shows. –Mayo Clinic|2013-05-19
News Tip: New Research on Teenage Girls and Melanoma Makes This the Season for Tanning Stories
Prom season and summer approach, and with them teenage girls seeking suntans. New research published in the May issue of Pediatrics finds that the number of children diagnosed with melanoma has increased an average 2% a year since the 1970s. –Dana-Farber Cancer Institute|2013-05-17
Prostate Cancer Researchers Begin Clinical Trial to Evaluate Cancer-Fighting Drug TherapyPatients with advanced metastatic prostate cancer and poor prognoses are focus of new Cedars-Sinai study. –Cedars-Sinai Medical Center|2013-05-16
Expert on BRCA1/BRCA2 Gene Mutations & Risk of Breast and Ovarian Cancers Available for Interviews
–Fred Hutchinson Cancer Research Center|2013-05-16
Doctors Should Discuss Financial Concerns of Cancer PatientsMost cancer patients would like to talk about the cost of their care with their doctors, but often don't because they fear the discussion could compromise the quality of their treatment, researchers at Duke Cancer Institute report. –Duke Medicine|2013-05-16
New Protein-Targeting Drug Shows Promise in Early Trial for Patients with High-Risk CLL
Dana-Farber investigators led a phase 1 trial in which a new oral targeted drug, idelalisib, (GS-1101), showed the potential to stave off the need for additional treatments for relapsed or treatment-resistant CLL. –Dana-Farber Cancer Institute|2013-05-15
UH Case Medical Center Experts to Present Data at ASCO On Patient and Physician Barriers to Clinical TrialsResearchers from University Hospitals Case Medical Center’s (UHCMC) Seidman Cancer Center will present findings from two studies evaluating new technologies designed to address common barriers to patient enrollment in clinical trials. Results from a large-scale, randomized trial demonstrated that the use of tailored, web-based videos delivering educational information to patients before an oncologist visit can significantly improve knowledge and reduce attitudinal barriers that impact enrollment in clinical trials. A second, preliminary study showed that a new automated technology created by UHCMC researchers helped oncologists identify clinical trials for individual patients in a busy outpatient oncology clinic. –University Hospitals Case Medical Center|2013-05-15
PARP Inhibitor Shows Activity in Pancreatic, Prostate Cancers Among Patients Carrying BRCA MutationsIn the largest clinical trial to date to examine the efficacy of PARP inhibitor therapy in BRCA 1/2 carriers with diseases other than breast and ovarian cancer, the oral drug olaparib was found to be effective against advanced pancreatic and prostate cancers. Results of the study, led by researchers from the Perelman School of Medicine at the University of Pennsylvania and Sheba Medical Center in Tel Hashomer, Israel, will be presented during the American Society of Clinical Oncology’s annual meeting in Chicago in early June (Abstract #11024). –Perelman School of Medicine at the University of Pennsylvania |2013-05-15
Study Finds Broad Support for Rationing of Some Types of Cancer CareThe majority of cancer doctors, patients, and members of the general public support cutting health care costs by refusing to pay for drugs that don’t improve survival or quality of life, according to results of a new study that will be presented by researchers from the Perelman School of Medicine at the University of Pennsylvania during the annual meeting of the American Society of Clinical Oncology in Chicago in early June (Abstract #6518). –Perelman School of Medicine at the University of Pennsylvania |2013-05-15
Skin Cancer Does Not Discriminate - Excessive UV Exposure Can Damage All Skin TypesMontefiore Dermatologist Urges Year-Round Skin Protection for People of Color –Montefiore Medical Center|2013-05-15
NIH Saves Lives: Fred Hutchinson Cancer Research Center Calls on Congress to Restore Full Funding
Fred Hutchinson Cancer Research Center, one of the nation’s top cancer research and prevention centers and pioneer of bone marrow and stem cell transplantation, today called on Congress to support restoring full funding to the National Institutes of Health (NIH), which supports pioneering research that saves lives. Funding was recently cut due to sequestration. –Fred Hutchinson Cancer Research Center|2013-05-15
Scheduled Imaging Studies Provide Little Help Detecting Relapse of Aggressive LymphomaImaging scans following treatment for diffuse large B-cell lymphoma do little to help detect a relapse, a Mayo Clinic study has found. The overwhelming majority of patients with this aggressive lymphoma already have symptoms, an abnormal physical exam or an abnormal blood test at the time of relapse, the researchers say. The findings will be presented at the American Society of Clinical Oncology annual meeting May 31-June 4 in Chicago. –Mayo Clinic|2013-05-15
Skin Cancer May Be Linked to Lower Risk of Alzheimer’s DiseasePeople who have skin cancer may be less likely to develop Alzheimer's disease, according to new research published in the May 15, 2013, online issue of Neurology®, the medical journal of the American Academy of Neurology. The link does not apply to melanoma, a less common but more aggressive type of skin cancer. –American Academy of Neurology (AAN)|2013-05-15
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