Released: 18-Oct-2005 10:00 AM EDT
Statins Decrease Restenosis in Patients with High CRP Levels
Cardiovascular Research Foundation (CRF)

Treatment with statins, which have an anti-inflammatory effect and reduce C-reactive protein levels, have been shown to decrease the risk of periprocedural coronary events.

Released: 18-Oct-2005 10:00 AM EDT
Cryoplasty Effectively Treats Challenging Peripheral Artery Blockages
Cardiovascular Research Foundation (CRF)

Research has shown that cryoplasty, a minimally-invasive treatment that utilizes freezing-cold nitrous oxide injected into an angioplasty balloon, appears to be more effective than standard therapies in the treatment of peripheral artery disease in the lower limbs.

Released: 18-Oct-2005 10:00 AM EDT
Device Removes Plaque Prior to Revascularization in Peripheral Arterial Disease Patients
Cardiovascular Research Foundation (CRF)

A new study has shown that plaque excision with a new device called the SilverHawk is beneficial as a primary therapy in revascularization of lower extremity peripheral arterial disease.

Released: 18-Oct-2005 10:00 AM EDT
New Device Uses Radiofrequency Energy for PFO Closure
Cardiovascular Research Foundation (CRF)

Results are available from the first-ever human trial of a new device that uses radiofrequency energy to close a patent foramen ovale, a flap-like opening between the upper chambers of the heart. PFO closures have been successfully performed for more than 10 years using catheters to insert permanent devices to seal a PFO.

Released: 18-Oct-2005 10:00 AM EDT
New Device Brings Hope to Severe Heart Disease Patients
Cardiovascular Research Foundation (CRF)

Very promising one-year results from the first study of a new minimally invasive procedure that uses a small clip to help properly close the leaflets of the mitral valve in patients with mitral regurgitation are available.

Released: 18-Oct-2005 10:00 AM EDT
Bone Marrow Stem Cell Transplants Improve Heart Function
Cardiovascular Research Foundation (CRF)

An encouraging study has shown that transplantation of bone marrow stem cells into the heart improves heart function and blood flow in heart attack patients for up to six months.

Released: 18-Oct-2005 10:00 AM EDT
Self-Contained MRI Catheter Allows Identification of Vulnerable Coronary Plaque
Cardiovascular Research Foundation (CRF)

Results from the first-in-man trial of a self-contained magnetic resonance imaging catheter designed to evaluate the composition of plaque found in the heart are available.

Released: 25-Oct-2006 8:40 AM EDT
Cardiovascular Research Foundation’s Eighteenth Annual TCT Scientific Symposium
Cardiovascular Research Foundation (CRF)

TCT Hot Topic Press Conferences: Interactive Q&A press briefings to be held on Wednesday, October 25 at the Cardiovascular Research Foundation's (CRF) eighteenth annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium in Washington, D.C

Released: 17-Nov-2014 5:00 PM EST
Big Data Study Identifies New Potential Target Coating for Drug-Eluting Stents
Cardiovascular Research Foundation (CRF)

A new study has identified an FDA approved cancer drug, crizotinib, as a possible new coating for drug-eluting stents. Researchers found that crizotinib in mice helped prevent the narrowing of blood vessels after stenting without affecting the blood vessel lining. Results of this study were published today in The Journal of Clinical Investigation.

Released: 12-Jan-2015 11:55 AM EST
Novella Clinical and the Cardiovascular Research Foundation Collaborate to Provide Comprehensive Clinical Trial Expertise
Cardiovascular Research Foundation (CRF)

Novella Clinical, a Quintiles company (Novella), and the Cardiovascular Research Foundation (CRF) today announced a preferred provider collaboration that will offer a set of clinical trial services to developers of cardiovascular drugs and devices.

Released: 2-Feb-2015 1:00 PM EST
Agenda Available for CTO Summit 2015
Cardiovascular Research Foundation (CRF)

The CTO Summit 2015 is a two-day course featuring the latest research and state-of-the-art technologies for chronic total occlusions.

Released: 17-Mar-2015 3:05 AM EDT
Meta-Analysis Finds Extended Dual Antiplatelet Therapy Associated with Increased Mortality after Drug-Eluting Stent Implantation
Cardiovascular Research Foundation (CRF)

Data from a meta-analysis published today in The Lancet found that extended duration dual antiplatelet therapy (DAPT) after drug-eluting stent (DES) implantation was associated with significantly higher rates of mortality compared to shorter DAPT.

Released: 17-Mar-2015 3:05 AM EDT
Multicenter Trial Demonstrates Superiority of Bivalirudin to Heparin Monotherapy and Heparin with Tirofiban in Patients with Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention
Cardiovascular Research Foundation (CRF)

Data from the BRIGHT trial published today in the Journal of the American Medical Association demonstrated that bivalirudin was superior to both heparin monotherapy and heparin plus tirofiban for patients with acute myocardial infarction (AMI) undergoing percutaneous coronary intervention (PCI). Findings were first reported at last year’s Transcatheter Cardiovascular Therapeutics (TCT), the annual scientific symposium of the Cardiovascular Research Foundation (CRF).

Released: 27-Apr-2015 11:05 AM EDT
Media Registration Now Open for TCT 2015
Cardiovascular Research Foundation (CRF)

TCT 2015 (Transcatheter Cardiovascular Therapeutics) is the annual Scientific Symposium of the Cardiovascular Research Foundation (CRF). TCT is the world’s premier educational meeting specializing in interventional cardiovascular medicine.

Released: 30-Apr-2015 2:05 PM EDT
Agenda Available for TVT 2015
Cardiovascular Research Foundation (CRF)

TVT 2015 is a three-day course featuring the latest research and state-of-the-art techniques for transcatheter, aortic, and mitral valve therapies. This year’s conference will emphasize advanced imaging, bioskill demonstrations, and live case transmissions featuring the world’s leading experts.

Released: 20-May-2015 2:05 PM EDT
Analysis Compares Stent Expansion Achieved with Guidance from Optimal Coherence Tomography Versus Intravascular Ultrasound
Cardiovascular Research Foundation (CRF)

Data from the ILUMIEN II trial found that guidance from optimal coherence tomography (OCT) was associated with comparable stent expansion as guidance from intravascular ultrasound (IVUS) in patients undergoing percutaneous coronary intervention (PCI). Results from the study were presented today at EuroPCR 2015, the official annual meeting of the European Association for Percutaneous Cardiovascular Interventions.

Released: 10-Jun-2015 9:05 AM EDT
Interventional Cardiovascular Device Development: Considerations in Clinical Trial Implementation, New Webinar Hosted by Xtalks
Cardiovascular Research Foundation (CRF)

Novella Clinical and the CRF Clinical Trials Center will conduct webinar on how medical device developers can avoid the pitfalls and challenges of conducting cardiovascular clinical trials.

Released: 21-Aug-2015 7:05 PM EDT
Announcing the TCT 2015 Late-Breaking Trials and First Report Investigations
Cardiovascular Research Foundation (CRF)

The Cardiovascular Research Foundation (CRF) has announced the late-breaking trials and first report investigations that will be presented at the Transcatheter Cardiovascular Therapeutics (TCT) 2015 scientific symposium.

Released: 14-Sep-2015 4:05 PM EDT
The Cardiovascular Research Foundation Hosts 5K in Honor of Slain Cardiologist
Cardiovascular Research Foundation (CRF)

To honor the life and work of Dr. Michael Davidson, the Cardiovascular Research Foundation (CRF) has partnered with the San Francisco Giants to host the Dr. Michael Davidson 5K Run/Walk during Transcatheter Cardiovascular Therapeutics (TCT), the world’s premier educational meeting specializing in interventional cardiovascular medicine.

Released: 16-Sep-2015 5:05 PM EDT
Jason Ware Joins CRF as Director, Meeting Planning
Cardiovascular Research Foundation (CRF)

The Cardiovascular Research Foundation (CRF) announced that Jason Ware has joined the organization as Director, Meeting Planning. In this role, Ware oversees the meeting planning function of the CRF Center for Education. His responsibilities include managing a staff of meeting planners and working with vendors and internal resources to execute the logistics for CRF educational meetings throughout the year.

Released: 22-Sep-2015 1:05 PM EDT
CRF Announces Press Conference Schedule for TCT 2015
Cardiovascular Research Foundation (CRF)

CRF has announced the press conference schedule for late-breaking trials and first report investigations that will be presented at the TCT 2015 scientific symposium. TCT, the world’s premier educational meeting specializing in interventional cardiovascular medicine, will take place October 11-15, 2015 in San Francisco, California.

Released: 28-Sep-2015 1:00 PM EDT
Data Presented at TCT 2015 Will Demonstrate Whether The "Disappearing" Stent Is a Major Breakthrough in Angioplasty
Cardiovascular Research Foundation (CRF)

Noteworthy data will be presented at Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium next month on several trials examining the use of cardiovascular stents (or “scaffolds”) that are absorbed back into the body over time.

Released: 14-Oct-2015 10:05 AM EDT
Shelley Wood Joins the Cardiovascular Research Foundation as Editorial Director
Cardiovascular Research Foundation (CRF)

The Cardiovascular Research Foundation (CRF) announced today that Shelley Wood will join the organization as Editorial Director on October 15. Ms. Wood will lead CRF’s editorial services department and be responsible for developing original, thought-provoking, and clinically relevant content for TCTMD, the leading online resource for cutting-edge news and information in interventional cardiovascular medicine. She will also play an integral role in ongoing enhancements of the TCTMD website.

Released: 24-Nov-2015 2:05 PM EST
The Cardiovascular Research Foundation Joins the Global #GivingTuesday Movement
Cardiovascular Research Foundation (CRF)

The Cardiovascular Research Foundation (CRF) has joined #GivingTuesday, a global day of giving that harnesses the collective power of individuals, communities and organizations to encourage philanthropy and to celebrate generosity worldwide. This year 100% of the donations to CRF made on Giving Tuesday will go directly to the CRF Fellows Fund, which was established to mentor the next generation of cardiovascular researchers and provide financial support for the rapid advancement of breakthrough treatments needed in the fight against heart disease, the #1 killer of men and women worldwide.

Released: 30-Nov-2015 2:05 PM EST
Michael O’Riordan Joins the Cardiovascular Research Foundation as Senior Editorial Journalist for TCTMD
Cardiovascular Research Foundation (CRF)

The Cardiovascular Research Foundation (CRF) is pleased to announce that Michael O’Riordan joins the organization today as Senior Editorial Journalist for TCTMD, the leading online resource for cutting-edge news and information in interventional cardiovascular medicine.

Released: 27-Jan-2016 1:05 PM EST
Agenda Available for CTO Summit 2016
Cardiovascular Research Foundation (CRF)

The CTO Summit 2016 is a two-day course featuring the latest research and state-of-the-art technologies for chronic total occlusions. This year’s conference will emphasize advanced techniques, evidence-based medicine, and live case transmissions featuring the world’s leading experts in CTO stenting. Sessions showcasing the latest research on CTOs will focus on procedural outcomes, registry updates, and new stent technologies.

Released: 21-Mar-2016 3:05 PM EDT
TCTMD Launches New Podcast Network
Cardiovascular Research Foundation (CRF)

The Cardiovascular Research Foundation (CRF) is excited to announce the launch of TCTMD’s new podcast network, the Pulse of Cardiology. TCTMD is the leading online resource for cutting-edge news and information in interventional cardiovascular medicine, and beyond.

Released: 29-Mar-2016 12:05 PM EDT
CRF Physicians and Fellows to Present Abstracts at ACC.16
Cardiovascular Research Foundation (CRF)

Physicians and fellows from the Cardiovascular Research Foundation (CRF) will be presenting abstracts at the American College of Cardiology 65th Annual Scientific Session taking place April 2-4, 2016 at McCormick Place in Chicago, IL. They will be sharing the latest data on drug-eluting stents, imaging technologies, dual antiplatelet therapy, transcatheter aortic valve replacement, and bioresorbable vascular scaffolds.

Released: 31-Mar-2016 10:05 AM EDT
Daniel Burkhoff, MD, PhD Returns to the Cardiovascular Research Foundation as Director of Heart Failure, Hemodynamics and Circulatory Support
Cardiovascular Research Foundation (CRF)

The Cardiovascular Research Foundation (CRF) announced today that Daniel Burkhoff, MD, PhD, has returned to the organization as Director of Heart Failure, Hemodynamics and Circulatory Support in the CRF Clinical Trials Center (CTC).

Released: 11-Apr-2016 12:05 PM EDT
The Cardiovascular Research Foundation Unveils New Logo and Website
Cardiovascular Research Foundation (CRF)

The Cardiovascular Research Foundation (CRF), a nonprofit organization dedicated to heart disease research and education, launched a new logo and website today.

   
Released: 18-May-2016 11:05 AM EDT
The Cardiovascular Research Foundation Announces Office Move
Cardiovascular Research Foundation (CRF)

The Cardiovascular Research Foundation (CRF), a nonprofit organization dedicated to heart disease research and education, has announced it will be moving its corporate office to a new location in midtown Manhattan.

Released: 7-Jun-2016 12:05 PM EDT
Agenda Available for TVT 2016
Cardiovascular Research Foundation (CRF)

TVT 2016 is a three-day course featuring the latest research and state-of-the-art techniques for transcatheter aortic and mitral valve therapies. This year’s conference will emphasize advanced imaging, bioskill demonstrations, and live case transmissions featuring the world’s leading experts.

Released: 28-Jun-2016 2:05 PM EDT
Media Registration Now Open for TCT 2016
Cardiovascular Research Foundation (CRF)

TCT (Transcatheter Cardiovascular Therapeutics), is the annual Scientific Symposium of the Cardiovascular Research Foundation (CRF). It is the world’s premier educational meeting specializing in interventional cardiovascular medicine and attracts nearly 12,000 attendees from all over the world. Every year, TCT features major medical research breakthroughs and gathers leading researchers and clinicians from around the world to present and discuss the latest evidence-based research in the field.

Released: 27-Jul-2016 9:05 AM EDT
World-Renowned Athlete Magic Johnson to Speak at TCT 2016
Cardiovascular Research Foundation (CRF)

Earvin “Magic” Johnson will be a special keynote speaker at TCT 2016 (Transcatheter Cardiovascular Therapeutics), the annual scientific symposium of the Cardiovascular Research Foundation (CRF). TCT is the world’s premier educational meeting specializing in interventional cardiovascular medicine, attracting nearly 12,000 attendees from all over the world.

Released: 13-Sep-2016 3:05 PM EDT
Announcing the TCT 2016 Late-Breaking Trials and First Report Investigations
Cardiovascular Research Foundation (CRF)

The Cardiovascular Research Foundation (CRF) has announced the 11 late-breaking trials and 16 first report investigations that will be presented at the Transcatheter Cardiovascular Therapeutics (TCT) 2016 scientific symposium. TCT, the world’s premier educational meeting specializing in interventional cardiovascular medicine, will take place October 29 – November 2, 2016 at the Walter E. Washington Convention Center in Washington, DC.

Released: 26-Sep-2016 5:05 PM EDT
Announcing the TCT 2016 Press Conference Schedule
Cardiovascular Research Foundation (CRF)

The Cardiovascular Research Foundation (CRF) has announced the press conference schedule for late-breaking trials and first report investigations that will be presented at the Transcatheter Cardiovascular Therapeutics (TCT) 2016 scientific symposium. TCT, the world’s premier educational meeting specializing in interventional cardiovascular medicine, will take place October 29 – November 2 in Washington, DC.

Released: 24-Oct-2016 11:05 AM EDT
Early Feasibility and First-in-Human Studies to Be Highlighted at TCT 2016
Cardiovascular Research Foundation (CRF)

The 28th annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium sponsored by the Cardiovascular Research Foundation (CRF) will feature a number of first-in-human and early feasibility trials that could impact future clinical practice. TCT, the world’s premier educational meeting specializing in interventional cardiovascular medicine, will take place October 29 – November 2, 2016 at the Walter E. Washington Convention Center in Washington, DC.

Released: 26-Oct-2016 10:05 AM EDT
Announcing the New TCTMD!
Cardiovascular Research Foundation (CRF)

The Cardiovascular Research Foundation (CRF) is pleased to announce the launch of the new TCTMD (www.tctmd.com), the leading online resource for cutting-edge news and information in interventional cardiology and beyond.

Released: 29-Oct-2016 3:05 PM EDT
The Cardiovascular Research Foundation Announces New Journal Focusing on Structural Heart Disease
Cardiovascular Research Foundation (CRF)

The Cardiovascular Research Foundation (CRF) is pleased to announce the launch of a new international journal focusing on the diagnosis and treatment of structural heart disease and the importance of the heart team in managing these disorders.

Released: 30-Oct-2016 10:05 AM EDT
Study Finds Ridaforolimus-Eluting Stent Is Non-Inferior to Zotarolimus-Eluting Stent Based on One-Year Clinical Outcomes
Cardiovascular Research Foundation (CRF)

The large multinational randomized BIONICS study found that a novel ridaforolimus-eluting stent (BioNIR) was non-inferior to a zotarolimus-eluting stent (Resolute) for one-year clinical outcomes in a broad, less selected ‘more comers’ population. Results of this trial will be submitted to the FDA for U.S. approval of this novel drug-eluting stent.

Released: 30-Oct-2016 11:05 AM EDT
Study Examines Use of Optical Coherence Tomography Compared to Intravascular Ultrasound and Angiography to Guide Coronary Stent Implantation
Cardiovascular Research Foundation (CRF)

Although percutaneous coronary intervention (PCI) is most commonly guided by angiography alone, results from a new study investigating adjunctive imaging modalities showed that the use of a novel optical coherence tomography (OCT)-based stent sizing strategy results in similar minimal stent area (MSA) compared to intravascular ultrasound (IVUS)-guided PCI. Imaging-guided PCI (with both OCT and IVUS) also resulted in improved stent expansion and acute stent-based procedural success compared to angiography-guided PCI.

Released: 30-Oct-2016 11:05 AM EDT
Very Thin-Strut Biodegradable Polymer Everolimus-Eluting and Sirolimus-Eluting Stents Shown to Be Non-Inferior to Durable Polymer Zotarolimus-Eluting Stents in All-Comers with Coronary Artery Disease
Cardiovascular Research Foundation (CRF)

Results of a large-scale, multicenter study found that treatment with two thin-strut drug-eluting stents were both non-inferior to a durable polymer drug-eluting stent and showed favorable clinical outcomes at one year in treating an all-comers population with a high proportion of patients with acute coronary syndromes.

Released: 30-Oct-2016 1:05 PM EDT
Study Confirms Polymer-Free Drug-Coated Stents Safer and More Effective Than Bare-Metal Stents in Patients at High Risk for Bleeding Treated with One Month of Dapt
Cardiovascular Research Foundation (CRF)

The two-year results from LEADERS FREE, the first randomized clinical trial dedicated to high bleeding risk patients treated with one month of dual antiplatelet therapy (DAPT), found that a polymer-free drug-coated stent (DCS) remained both significantly safer and more effective than the comparator bare-metal stent (BMS) used in the trial.

Released: 31-Oct-2016 9:05 AM EDT
Trial Results Suggest That Drug-Eluting Stents Are Acceptable Alternative toOpen Heart Surgery for Select Patients with Left Main Coronary Artery Disease
Cardiovascular Research Foundation (CRF)

A large-scale randomized trial examining percutaneous coronary intervention (PCI) versus coronary artery bypass graft surgery (CABG) in patients with left main coronary artery disease (LMCAD) and low-intermediate SYNTAX scores found that there was no significant difference in three-year outcomes between the two treatments, with a reduction in 30-day major adverse events with PCI.

Released: 31-Oct-2016 9:05 AM EDT
Study Indicates That Open Heart Surgery May Be Superior to PCI for Treatment of Left Main Coronary Artery Disease
Cardiovascular Research Foundation (CRF)

Coronary artery bypass (CABG) surgery is the standard treatment for revascularization in patients with left main coronary artery (LMCA) disease, but use of percutaneous coronary intervention (PCI) for this indication is increasing. Findings from the Nordic–Baltic–British Left Main Revascularization Study (NOBLE) trial found that despite similar mortality, the five-year risk of major adverse events was higher after PCI compared to CABG for the treatment of unprotected LMCA disease.

Released: 31-Oct-2016 12:05 PM EDT
First-in-Human of New Polymer-Free Stent Demonstrates Favorable Angiographic and Imaging-Based Outcomes at Nine-Months
Cardiovascular Research Foundation (CRF)

A first-in-human study of a new polymer-free drug-filled stent, which provides controlled drug elution from an internal lumen, indicated non-inferior in-stent late lumen loss at nine-months compared with historical zotarolimus-eluting stent (Resolute) data. In addition, there was no binary restenosis, and a high degree of early stent strut coverage with minimal malapposition.

Released: 31-Oct-2016 12:05 PM EDT
TCT 2016 First Report Investigations Examine Potential for Novel Bioresorbable Stent Technologies
Cardiovascular Research Foundation (CRF)

The 28th annual Transcatheter Cardiovascular Therapeutics (TCT), the annual scientific symposium of the Cardiovascular Research Foundation (CRF) featured a number of first report investigations on novel stents that could become the next generation of bioresorbable stents in patients.

Released: 1-Nov-2016 9:05 AM EDT
Study Finds Use of Adjunctive Cerebral Embolic Protection During Transcatheter Aortic Valve Replacement Was Safe but Improvement in MRI Findings Did Not Reach Statistical Significance
Cardiovascular Research Foundation (CRF)

A multicenter randomized trial evaluating the role of embolic protection using the Sentinel device during transcatheter aortic valve replacement (TAVR) found that the device was safe but did not meet the primary efficacy endpoint of reduction in median new lesion volume in protected territories assessed by MRI at 2-7 days. In addition, neurocognitive function was not significantly improved.

Released: 1-Nov-2016 10:05 AM EDT
Patients with Severe Aortic Stenosis and Intermediate Surgical Risk Show Similar Late Quality of Life Outcomes Following Either Transcatheter or Surgical Aortic Valve Replacement
Cardiovascular Research Foundation (CRF)

Patients with severe aortic stenosis (AS) at intermediate surgical risk, and who are treated with transcatheter aortic valve replacement (TAVR) had improved health status at one month compared with surgical aortic valve replacement (SAVR) but two-year quality of life outcomes were similar. Prior studies have shown that TAVR results in an early quality of life (QoL) benefit in patients at high surgical risk; however, the effect of TAVR versus. SAVR on QoL in intermediate risk patients was unknown prior to this study.

Released: 1-Nov-2016 10:05 AM EDT
Five Year Echocardiogram Follow-Up Data Demonstrates Sustained Durability After Transcatheter Aortic Valve Replacement in High-Risk and Inoperable Patients
Cardiovascular Research Foundation (CRF)

A substudy of the PARTNER I Trial and Continued Access Registry found that hemodynamic trends in patients who received transcatheter aortic valve replacement (TAVR) showed excellent durability without significant structural valve deterioration at five years. The trial represents the largest to-date longitudinal analysis of echocardiographic hemodynamic parameters systematically assessed by a core laboratory.


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