Postmenopausal women who take combined estrogen/progestin hormone-replacement therapy for three years or more face a fourfold increased risk of developing various forms of lobular breast cancer, according to new findings by researchers at Fred Hutchinson Cancer Research Center.
Rapid evolution of a protein produced by an immunity gene is associated with increased antiviral activity in humans, a finding that suggests evolutionary biology and virology together can accelerate the discovery of viral-defense mechanisms, according to researchers at Fred Hutchinson Cancer Research Center.
Use of vitamin and mineral supplements among cancer survivors is widespread, despite inconclusive evidence that such use is beneficial, according to a comprehensive review of scientific literature conducted by researchers at Fred Hutchinson Cancer Research Center and published Feb. 1 in the Journal of Clinical Oncology.
A team of researchers led by Fred Hutchinson Cancer Research Center has identified a new mechanism that explains why some recurrent ovarian tumors become resistant to treatment with commonly used platinum-based chemotherapy drugs such as cisplatin and carboplatin.
Men who eat a diet low in fat and red meat but high in vegetables and lean protein and who drink alcohol in moderation may not just be doing their hearts a favor. A new study shows that such a heart-healthy diet may also be good for the prostate.
A new offering for climbers "“ "Volcanoes of Mexico" "“ highlights the 2008 Climb to Fight Breast Cancer® benefiting Fred Hutchinson Cancer Research Center. The Climb has expanded its international slate of peaks, enabling outdoor enthusiasts of all skill levels to challenge themselves in honor or memory of loved ones who have battled breast cancer.
An outbreak of pandemic influenza in the U.S. could be mitigated with prompt implementation of social-distancing measures combined with antiviral treatment and prophylaxis until a vaccine is available.
Most people assume that cancer is genetic and cannot be avoided. However, according to the American Cancer Society, healthy behaviors could prevent approximately half of cancer deaths. Fred Hutchinson Cancer Research Center cancer-prevention expert Anne McTiernan, M.D., Ph.D., offers 10 lifestyle changes, all based on the latest research, that people can make to improve their odds of preventing cancer or catching it at its earliest, most curable stages.
The risk of the two major prostate diseases, cancer and benign prostatic hyperplasia (BPH), can be reduced by changes in lifestyle, such as avoiding smoking, maintaining a normal weight and eating a healthy diet. Alan Kristal, Dr.P.H., associate head of the Cancer Prevention Program at Fred Hutchinson Cancer Research Center in Seattle, has conducted many studies that suggest men need not feel helpless against prostate cancer or BPH.
Therapies under development to treat prostate cancer by inhibiting the ability of insulin-like growth factor (IGF-1) to activate its target receptor could have unexpected results especially if a major tumor suppressor gene "“ p53 "“ is already compromised.
Cutting the umbilical cord doesn't necessarily sever the physical link between mother and child. Many cells pass back and forth between the mother and fetus during pregnancy and can be detected in the tissues and organs of both even decades later. This mixing of cells from two genetically distinct individuals is called microchimerism. The phenomenon is the focus of an increasing number of scientists who wonder what role these cells play in the body.
Researchers at Fred Hutchinson Cancer Research Center have a lead role in a new public/private partnership to create the first systematic surveillance program of men with prostate cancer to look for biological clues to help determine when to wait and when to treat the disease. The project was announced by the Canary Foundation and the National Cancer Institute.
Evolution is supposed to inch forward over eons, but sometimes, at least in the case of a little fish called the threespine stickleback, the process can go in relative warp-speed reverse, according to a study led by researchers at Fred Hutchinson Cancer Research Center.
A team of researchers at Fred Hutchinson Cancer Research Center has uncovered what may be the key to understanding how prostate tumors eventually become resistant to androgen-deprivation therapy.
A multicenter team of researchers has identified a panel of proteins linked to early development of pancreatic cancer in mice that applies also to early stages of the disease in humans "“ a breakthrough that brings scientists a significant step closer to developing a blood test to detect the disease early, when cure rates are highest.
Researchers describe the first successful use of a human patient's cloned infection-fighting T cells as the sole therapy to put an advanced solid-tumor cancer into long-term remission.
Women's reports of persistent, recent-onset symptoms linked to ovarian cancer "“ abdominal or pelvic pain, difficulty eating or feeling full quickly and abdominal bloating "“ when combined with the CA125 blood test may improve the early detection of ovarian cancer by 20 percent, according to new findings by researchers at Fred Hutchinson Cancer Research Center published online today in CANCER.
For the first time, researchers have demonstrated that the administration of minute amounts of inhaled or intravenous hydrogen sulfide, or H2S "“ the molecule that gives rotten eggs their sulfurous stench "“ significantly improves survival from extreme blood loss in rats.
Scientists at Fred Hutchinson Cancer Research Center have discovered that microRNAs "“ molecular workhorses that regulate gene expression "“ are released by cancer cells and circulate in the blood, which gives them the potential to become a new class of biomarkers to detect cancer at its earliest stages.
A statement from Larry Corey, MD, of the HIV Vaccine Trials Network regarding the new HIV infection statistics released today by the Centers for Disease Control.
A team of researchers led by Fred Hutchinson Cancer Research Center reports online today in the Journal of Clinical Oncology the validation of a potential "HIV-test" equivalent for the early detection of lung cancer. The test, which relies on immune-system signals, much like an HIV test, can detect the presence of lung cancer a year prior to diagnosis, long before symptoms appear.
For women whose breast cancer has spread to their lymph nodes, a magnetic resonance imaging (MRI) scan could replace exploratory surgery as the method for determining whether those women need radiation therapy to treat their disease, according to a study to be presented during the annual meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO) which opens today in Boston.
A special supplement of the Oct. 15 journal Cancer for the first time details guidelines for low- and middle-income countries to implement breast cancer programs to detect and treat the most common disease among women worldwide.
Fred Hutchinson Cancer Research Center today announced a video contest called "Get Screened" "“ a creative challenge to movie makers to help shine a spotlight on the importance of colorectal-cancer screening. The contest is part of the Hutchinson Center's ongoing awareness campaign "” "Your colon. Your life. Your call." "” to increase colon-cancer screening rates and reduce deaths from the disease in Washington state.
Women who suffer from migraines may take at least some comfort in a recent, first-of-its-kind study that suggests a history of such headaches is associated with a significantly lower risk of breast cancer.
There's still a month left for movie makers to enter Fred Hutchinson Cancer Research Center's "Get Screened" video contest "“ a creative challenge to help shine a spotlight on the importance of colorectal-cancer screening. All entries are due by Jan. 15, 2009.
The deadline to enter Fred Hutchinson Cancer Research Center's "Get Screened" video contest "“ a creative challenge to help shine a spotlight on the importance of colorectal-cancer screening "“ has been extended to Jan. 30.
Fred Hutchinson Cancer Research Center's stem-cell transplant program at the Seattle Cancer Care Alliance (SCCA) was one of only two transplant programs nationwide that consistently outperformed the expected one-year survival rate for unrelated donor transplants, according to an independent report that assessed 122 transplant centers over a five-year period.
Frequent and/or long-term marijuana use may significantly increase a man's risk of developing the most aggressive type of testicular cancer, according to a new study. Being a marijuana smoker at the time of diagnosis was associated with a 70 percent increased risk of testicular cancer. The risk was particularly elevated for frequent and long-term users.
The largest study of its kind concludes that long-term multivitamin use has no impact on the risk of common cancers, cardiovascular disease or overall mortality in postmenopausal women.
This is a feature idea based on unpublished research (will be published this spring) about college students and casual smoking. The lead researcher is available as an expert about casual smoking and its health impacts, as well as about smoking cessation.
The largest study of its kind to evaluate the effect of red versus white wine on breast-cancer risk concludes that both are equal offenders when it comes to increasing breast-cancer risk.
Terminally ill patients and their family caregivers often feel abandoned by their doctors and feel a sense of "unfinished business" with them, according to a new study by an oncologist at the Seattle Cancer Care Alliance.
Fred Hutchinson Cancer Research Center today announced the winners of its "Get Screened" video contest "“ a creative challenge to moviemakers nationwide to help shine a spotlight on the importance of colorectal-cancer screening. The five winning videos "“ featuring a stirring survivorship story, a probing puppet and a sinister character named "Colon Polyp," among other compelling characters "“ were selected from a pool of more than 60 submissions from contestants spanning 18 states and the District of Columbia.
A study led by researchers at Fred Hutchinson Cancer Research Center has identified two proteins in the blood that could become important prognostic markers for long-term survival in breast cancer patients. The proteins are associated with chronic inflammation, which is known to contribute to cancer development and progression.
The Fred Hutchinson Cancer Research Center board of trustees today announced that its president and director, Lee Hartwell, Ph.D., plans to retire in June 2010.
The relationship between migraine headaches in women and a significant reduction in breast cancer risk has been confirmed in a follow-on study to landmark research published last year and conducted by scientists at Fred Hutchinson Cancer Research Center. The new study found a 26 percent reduced risk of breast cancer among both premenopausal and postmenopausal women with a clinical diagnosis of migraines.
President Obama today announced that two Fred Hutchinson Cancer Research Center investigators have been awarded the nation's highest honor for scientists at the beginning of their independent research careers.
The latest drug regimens, vaccines and diagnostic tools under development to combat tuberculosis could have a potentially large impact on the disease once they become available, according to research findings published in the Aug. 3 early edition online of the Proceedings of the National Academy of Sciences.
Regular yoga practice is associated with mindful eating, and people who eat mindfully are less likely to be obese, according to a study led by researchers at Fred Hutchinson Cancer Research Center.
While long-term tamoxifen use among breast cancer survivors decreases their risk of developing the most common, less aggressive type of second breast cancer, such use is associated with a more than four-fold increased risk of a more aggressive, difficult-to-treat type of cancer in the breast opposite, or contralateral, to the initial tumor.
Scientific dogma has long asserted that females are born with their entire lifetime’s supply of eggs, and once they’re gone, they’re gone. New findings by researchers at Fred Hutchinson Cancer Research Center, published online Aug. 27 in Science, suggest that in nematode worms, at least, this does not hold true.
An aggressive vaccination program that first targets children and ultimately reaches 70 percent of the U.S. population would mitigate pandemic influenza H1N1 that is expected this fall, according to computer modeling and analysis of observational studies conducted by researchers at the Vaccine and Infectious Disease Institute (VIDI) at Fred Hutchinson Cancer Research Center.
A new study by researchers at Fred Hutchinson Cancer Research Center, published online Sept. 8 in the Journal of Clinical Oncology has found that obesity, alcohol use and smoking all significantly increase the risk of second breast cancer among breast cancer survivors.
Scientists at Fred Hutchinson Cancer Research Center have been awarded 60 research grants totaling nearly $40.4 million under the American Recovery & Reinvestment Act of 2009. The totals reflect data available as of Oct. 1 and reported by the National Institutes of Health. The individual projects range in amount from $4.8 million to $33,596 and benefit every level of researcher at the Hutchinson Center.
Researchers at Fred Hutchinson Cancer Research Center, Group Health Research Institute and the University of Washington schools of Public Health and Pharmacy have been selected to lead four projects backed by approximately $16 million in federal stimulus funding for comparative-effectiveness research in cancer. The grants establish Seattle as a national hub for conducting such research.
For the first time, researchers at Fred Hutchinson Cancer Research Center have demonstrated that it is possible to successfully recruit and retain a large number of adolescent smokers from the general population into a smoking intervention study and, through personalized, proactive telephone counseling, significantly impact rates of six-month continuous quitting.
Seattle and Ugandan researchers collaborate to study and treat infection-related cancers.
An expert in cancer proteomics at Fred Hutchinson Cancer Research Center has received $4.8 million in federal stimulus funding from the National Cancer Institute to co-lead a pilot study to assess the feasibility and scalability of a project that aims to measure all of the proteins in the human body.
Thomas Vaughan, M.D., head of the Epidemiology Program in the Public Health Sciences Division of Fred Hutchinson Cancer Research Center, has received a three-year, $7.9 million grant from the National Cancer Institute to study genetic susceptibility for Barrett’s esophagus and esophageal adenocarcinoma, a rapidly fatal cancer whose incidence has increased more than 500 percent in the past 30 years, faster than any other cancer in the United States.
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