Released: 25-Sep-1997 12:00 AM EDT
New Help for Parents Adopting Children from Overseas
University Hospitals Cleveland Medical Center

To meet the special needs of both adoptive parents and their children, Rainbow Babies and Childrens Hospital has developed a new program called the Rainbow Center for International ChildHealth. Children who are adopted from overseas sometimes carry rare diseases, or have psychological or behavioral problems associated with neglect or deprivation common to institutionalization.

Released: 12-Nov-1998 12:00 AM EST
New Cancer Drug Tested
University Hospitals Cleveland Medical Center

A cancer patient at the Ireland Cancer Center at University Hospitals of Cleveland is the first person in the world to be treated with a new class of drugs that targets and destroys cancer-feeding blood vessels.

9-Dec-2003 11:20 AM EST
Elderly Patients Achieve Seizure Freedom on Epilepsy Therapy
University Hospitals Cleveland Medical Center

According to the results of a study presented today, researchers found that treatment with the anti-epileptic drug (AED) Keppra (levetiracetam) used alone resulted in seizure freedom in elderly patients.

14-May-2013 6:00 PM EDT
UH Case Medical Center Experts to Present Data at ASCO On Patient and Physician Barriers to Clinical Trials
University Hospitals Cleveland Medical Center

Researchers from University Hospitals Case Medical Center’s (UHCMC) Seidman Cancer Center will present findings from two studies evaluating new technologies designed to address common barriers to patient enrollment in clinical trials. Results from a large-scale, randomized trial demonstrated that the use of tailored, web-based videos delivering educational information to patients before an oncologist visit can significantly improve knowledge and reduce attitudinal barriers that impact enrollment in clinical trials. A second, preliminary study showed that a new automated technology created by UHCMC researchers helped oncologists identify clinical trials for individual patients in a busy outpatient oncology clinic.

Released: 19-Jun-2013 4:45 PM EDT
UH Case Medical Center Among First to Enroll Patients for Global Carotid Artery Trial
University Hospitals Cleveland Medical Center

Physicians at University Hospitals Case Medical Center enrolled their first patients in the ROADSTER Study, a global, multicenter clinical trial evaluating a novel, less-invasive procedure to help clear blockages in carotid arteries and prevent strokes.

Released: 19-Jun-2013 4:55 PM EDT
University Hospitals Case Medical Center Launches Novel Clinical Trial Using Stem Cells to Prevent Amputation
University Hospitals Cleveland Medical Center

University Hospitals Case Medical Center clinical researchers have launched an innovative clinical trial, unique in its design, which will evaluate the ability of a patient’s own stem cells to prevent leg amputations in end stage peripheral arterial disease (PAD).

Released: 28-Jun-2013 3:40 PM EDT
University Hospitals Eye Institute to Offer ‘First Bionic Eye’ Retinal Chip for Blind
University Hospitals Cleveland Medical Center

University Hospitals Eye Institute will be one of the first medical centers in the United States to offer the Argus® II Retinal Prosthesis System (“Argus II”).

1-Jul-2013 5:00 PM EDT
University Hospitals Case Medical Center and Case Western Reserve University Announce Licensing Agreement for the Development of Diagnostic Tests for HIV Drug Resistance
University Hospitals Cleveland Medical Center

Case Western Reserve University has signed an exclusive worldwide licensing agreement granting University Hospitals (UH) Case Medical Center rights to a series of diagnostic tests to determine drug resistance and co-receptor tropism in human immunodeficiency virus (HIV).

Released: 19-Jul-2013 3:00 PM EDT
Harvard Expert in Glaucoma Douglas Rhee, MD, Named Chair of Ophthalmology and Visual Sciences at Case Western Reserve University School of Medicine and University Hospitals Case Medical Center
University Hospitals Cleveland Medical Center

After an extensive national search, Case Western Reserve University School of Medicine and University Hospitals Case Medical Center have named Douglas Rhee, MD, an accomplished glaucoma specialist, eye surgeon and researcher, chair of the Department of Ophthalmology and Visual Sciences.

Released: 23-Jul-2013 2:00 PM EDT
Estée Lauder Clinical Trial Finds Link Between Sleep Deprivation and Skin Aging
University Hospitals Cleveland Medical Center

In a first-of-its-kind clinical trial, physician-scientists at University Hospitals Case Medical Center found that sleep quality impacts skin function and aging. The study, commissioned by Estée Lauder, demonstrated that poor sleepers had increased signs of skin aging and slower recovery from a variety of environmental stressors, such as disruption of the skin barrier or ultraviolet (UV) radiation. Poor sleepers also had worse assessment of their own skin and facial appearance.

Released: 29-Aug-2013 10:00 AM EDT
New Imaging Technology Promising for Several Types of Cancer
University Hospitals Cleveland Medical Center

Researchers publish findings that a new form of imaging – PET/MRI – is promising for several types of cancer. Article is titled “PET/MRI: Applications in Clinical Imaging,” and is published in the September issue of Current Radiology Reports.

Released: 20-Sep-2013 8:00 AM EDT
UH Seidman Cancer Center Breaks Ground on $30 Million Proton Therapy Center
University Hospitals Cleveland Medical Center

University Hospitals Seidman Cancer Center breaks ground today on a $30 million center for proton therapy, an advanced type of radiation treatment that uses a powerful beam of protons to precisely target a tumor and at the same time reduce radiation to uninvolved tissues. There are currently only 11 operational proton therapy centers in the nation, and this will will be the first in Ohio. First patients will be in 2015.

Released: 26-Sep-2013 2:00 PM EDT
Colorectal Surgeons Develop a Novel Tool for Measuring Quality and Outcomes
University Hospitals Cleveland Medical Center

In a new paper published early online by the Annals of Surgery, physician-researchers at University Hospitals Case Medical Center describe a new tool called the HARM score that reliably measures quality and clinical outcomes for colon and rectal surgery patients. The name of the tool reflects the data sources used to calculate the score: HospitAl stay, Readmission rate, and Mortality. The paper demonstrates a strong correlation between the HARM score, and the quality of clinical outcomes achieved by surgeons and hospitals for patients having major abdominal surgery.

Released: 7-Oct-2013 11:40 AM EDT
Rising Trend in Genome Mapping Delivers Targeted Breast Cancer Treatment
University Hospitals Cleveland Medical Center

By studying the genetic makeup of breast cancer patients, doctors are taking the next steps forward in delivering more personalized care to patients. Whole genome sequencing from cancers is not a new concept, but recently researchers have delved more deeply into the evolution of breast cancers identifying that it comes in four distinct types. Breaking down how the cells of each sub-type of the disease function is allowing for doctors to customize treatments for improved outcomes.

Released: 7-Oct-2013 1:45 PM EDT
New Research Shows PET Imaging Effective in Predicting Lung Cancer Outcomes
University Hospitals Cleveland Medical Center

Advanced imaging with Positron Emission Tomography (PET) scan shows great promise in predicting which patients with inoperable lung cancer have more aggressive tumors and need additional treatment following standard chemotherapy/radiation therapy, according to new research recently published online in the Journal of Clinical Oncology. The multi-site trial, led by study author and principal investigator Mitch Machtay, MD, University Hospitals Case Medical Center Seidman Cancer Center, enrolled 250 patients at 60 cancer centers around the country.

Released: 21-Oct-2013 11:00 AM EDT
Recommendations for Clinical Trial Accrual Published in Journal of Oncology Practice
University Hospitals Cleveland Medical Center

CLEVELAND: New recommendations for overcoming issues related to cancer clinical trial accrual have been published online in the Journal of Oncology Practice. Following a National Cancer Institute (NCI) and American Society of Clinical Oncology (ASCO) co-sponsored symposium, the research team compiled a summary of best practices and strategies for future research aimed at advancing cancer trials more rapidly. “Cancer clinical trials provide the evidence base for new advances in oncology. However, only a few percent of cancer patients participate in them,” says Neal J. Meropol, MD, senior author, Chief of the Division of Hematology and Oncology at UH Case Medical Center and Case Western Reserve University School of Medicine. “Poor enrollment onto trials threatens to slow progress in cancer care at a time when advances in science are enabling new opportunities for prevention and treatment."

Released: 22-Oct-2013 3:00 PM EDT
From Neurodegeneration to Brain Health: An Integrated Approach -- Conference
University Hospitals Cleveland Medical Center

From Neurodegeneration to Brain Health: An Integrated Approach -- Conference

Released: 28-Oct-2013 11:00 AM EDT
Young Children with Asthma Visit Emergency Department Most Often, Fall Months the Busiest
University Hospitals Cleveland Medical Center

New research study finds that children ages 1 to 3 years account for one-fifth of all emergency department visits caused by complications from asthma, representing the highest proportion of visits among asthma patients under age 21. In addition, 55 percent of all ED visits due to asthma occur in boys, and fall months – September, October and November – have a relatively high proportion of visits compared to other times of the year. The research was presented at the American Academy of Pediatrics (AAP) National Conference in Orlando. At AAP, the same research team also presented an analysis of adverse drug events (ADE) among hospitalized children in the U.S. from 2003 to 2010. Results reveal that medication errors and ADEs in pediatric inpatient settings gradually increased between 2003 and 2010, although the cause for this increase requires further study.

Released: 21-Nov-2013 4:20 PM EST
Harrington Discovery Institute’s Dr. Jonathan Stamler earns AHA Distinguished Scientist Award
University Hospitals Cleveland Medical Center

Jonathan Stamler, MD, received the 2013 American Heart Association Distinguished Scientist Award at the association’s annual conference in Dallas. He discovered a process, termed S-nitrosylation, by which nitric oxide attaches to proteins to control cellular function.

Released: 26-Nov-2013 10:00 AM EST
Brain Bypass Surgery Gives Young Man His Life Back at University Hospitals
University Hospitals Cleveland Medical Center

A neuroradiologist inserts a micro-catheter into an aneurysm and injects a fluorescent dye, a complex, rare and new procedure which provides a neurosurgeon a clear view of the blood vessel that feeds the aneurysm. The surgeon then knows where to sew in a transplanted blood vessel to bypass the aneurysm.

2-Dec-2013 6:00 PM EST
UH Rainbow Babies & Children’s Hospital Only Northeast Ohio Hospital Named to Leapfrog’s Top Children’s Hospital Honor Roll
University Hospitals Cleveland Medical Center

University Hospitals Rainbow Babies & Children’s Hospital is one of only 13 children’s hospitals in the country – and the only one in northern Ohio – to receive the Top Children’s Hospital distinction from The Leapfrog Group. UH Rainbow was selected out of a record number of 1,324 hospitals participating in The Leapfrog Group’s annual survey.

Released: 12-Dec-2013 3:00 PM EST
New Research Uses Deep Sequencing of Breast Cancer Tumors to Predict Clinical Outcomes in Patients After Single Dose of Therapy
University Hospitals Cleveland Medical Center

New research examined how changes in the genetic composition of breast cancer tumors after brief exposure to either biologic therapy or chemotherapy can predict future clinical outcomes in patients.

Released: 18-Dec-2013 12:00 PM EST
New Center for Healthy Aging Helps Older Adults Live Fuller, More Independent Lives
University Hospitals Cleveland Medical Center

University Hospitals (UH) Bedford Medical Center, a campus of UH Regional Hospitals, has launched a new program to help older adults live healthier, more independent lives. The new center can serve as a model for working with older patients and their families.

8-Jan-2014 4:20 PM EST
Upper-Airway Electronic Stimulation Effective for Obstructive Sleep Apnea
University Hospitals Cleveland Medical Center

Promising results from a Phase III study published in this week’s New England Journal of Medicine finds upper airway electronic stimulation to be effective in reducing obstructive sleep apnea (OSA) symptoms.

Released: 13-Jan-2014 5:00 PM EST
Members of Blood Pressure Panel at Odds Over Recently Released Guidelines
University Hospitals Cleveland Medical Center

Minority of panel members who disagree with raising systolic blood pressure targets for people over 60 years of age provide their evidence in a new commentary in the Annals of Internal Medicine.

Released: 28-Jan-2014 1:00 PM EST
UH Rainbow Babies & Children’s Diabetes Physician-Researcher Charts Future Directions for Landmark Diabetes Study in Journal Diabetes Care
University Hospitals Cleveland Medical Center

Rose Gubitosi-Klug, MD, PhD, writes the summary and future directions in the journal Diabetes Care for a series of papers from Diabetes Control and Complications Trial (DCCT) and follow-up study Epidemiology of Diabetes Interventions and Complications (EDIC). The studies enrolled more than 1,400 adolescents and young adults with type 1 diabetes to evaluate if intensive control of diabetes could lower the risk of complications better than conventional control. EDIC continues to follow many of the original participants.

Released: 29-Jan-2014 10:00 AM EST
Study Finds Mammography Beneficial for Younger Women
University Hospitals Cleveland Medical Center

Researchers from University Hospitals Case Medical Center and Case Western Reserve University School of Medicine have published new findings in the February issue of American Journal of Roentgenology that mammography remains beneficial for women in their 40s. According to the study, women between ages 40 and 49 who underwent routine screening mammography were diagnosed at earlier stages with smaller tumors and were less likely to require chemotherapy.

Released: 7-Feb-2014 2:00 PM EST
Diaphragm Pacing in Spinal Cord Injury Successful in Weaning Patients From Ventilators, Bridging to Independent Respiration
University Hospitals Cleveland Medical Center

“This study provides several important observations,” said Dr. Raymond Onders, Director of Minimally Invasive Surgery at University Hospitals Case Medical Center. “Most notably, laparoscopic diaphragm mapping – an electronic reading of the diaphragm nerves – is safe and can be performed in multiple centers with success. In addition, early diaphragm mapping can quickly determine if a phrenic nerve injury is complete, allowing for early ventilator planning and prevention of weaning trials if we find the patient will not be able to be weaned from the ventilator. Finally, DP can successfully wean traumatic cervical SCI patients as evidenced by 72 percent of the implanted patients being completely weaned from ventilators and 36 percent with complete recovery and DP removal.

Released: 10-Feb-2014 5:00 PM EST
HIMSS Analytics Honors University Hospitals with Stage 6 Recognition
University Hospitals Cleveland Medical Center

Announcement by HIMSS Analytics that University Hospitals in Cleveland has achieved Stage 6 status on the EMR Adoption ModelSM (EMRAM).

Released: 18-Feb-2014 12:50 PM EST
UH Case Medical Center Among the First to Perform Major Heart Surgery Under ‘Twilight’
University Hospitals Cleveland Medical Center

New twilight sedation for advanced heart valve disease patients undergoing the minimally invasive TAVR, or transcatheter aortic valve replacement, cuts hospital stay, cost, and additional medications.

Released: 28-Feb-2014 3:00 PM EST
3 Ways to Love Your Heart
University Hospitals Cleveland Medical Center

Forty-nine percent of the adult population will have at least one risk factor for cardiovascular disease. Heart disease remains the leading cause of death in the United States The good news? It can be prevented. Judith Mackall, MD, Cardiologist at University Hospitals (UH) Case Medical Center in Cleveland, Ohio, offers three tips for men and women to help improve their heart health and reduce the risk of developing heart disease.

Released: 13-Mar-2014 1:00 PM EDT
Prostate Specific Antigen Screening Declines After 2012 USPSTF Recommendations
University Hospitals Cleveland Medical Center

Researchers at Case Western Reserve University and University Hospitals Case Medical Center have assessed the impact of the 2012 U.S. Preventive Services Task Force (USPSTF) recommendations against routine prostate specific antigen (PSA) cancer screenings, which cited evidence that the risks of screening outweigh the benefits. Results of the current study indicate that the USPSTF recommendations have resulted in a decrease in the number of PSA screenings ordered by doctors, with the greatest decline seen among urologists. The findings are published in the June issue of The Journal of Urology®.

Released: 13-Mar-2014 2:30 PM EDT
University Hospitals Case Medical Center Surgeons Perform Northeast Ohio’s First Auditory Brainstem Implant Operation
University Hospitals Cleveland Medical Center

Surgeons at University Hospitals Case Medical Center have completed the first auditory brainstem implant (ABI) operation in Northeast Ohio on a woman who has lost most of her hearing due to benign tumors on her auditory nerves.

13-Mar-2014 3:00 PM EDT
Pancreatic Cancer Surgery Findings Presented at Society of Surgical Oncology Cancer Symposium
University Hospitals Cleveland Medical Center

– Despite the benefits of surgery for early stage pancreatic cancer, it remains under-utilized for patients with this deadly disease, according to a new national analysis of trends and outcomes. Physician-scientists at University Hospitals (UH) Case Medical Center and Case Western Reserve University School of Medicine presented their findings and strategies to increase rates on March 13 at the Society of Surgical Oncology Cancer Symposium in Phoenix.

Released: 2-May-2014 10:00 AM EDT
University Hospitals Rainbow Babies & Children’s Hospital to Study African Americans Response to Asthma Medications
University Hospitals Cleveland Medical Center

The study of Best African American Response to Asthma Drugs (BARD) will examine whether African Americans respond differently to asthma therapies compared to Caucasians and will help to identify the best add-on therapy based on the patients’ age. Results of the BARD study will allow for evidence-based recommendations for the use of asthma medications in African Americans, significantly impacting national asthma guidelines.

5-May-2014 9:40 AM EDT
Researchers Present Findings on Promising Biomarker for Esophageal Cancer
University Hospitals Cleveland Medical Center

A new biomarker for esophageal cancer shows promise in improving screening for this deadly disease and its precursor, Barrett’s esophagus. Amitabh Chak, MD, of University Hospitals Case Medical Center’s Seidman Cancer Center and Case Western Reserve University School of Medicine, presented findings today at Digestive Disease Week in Chicago in a research forum titled “Aberrant Vimentin Methylation in Esophageal Brushings: A Biomarker for Detecting Barrett’s Esophagus and Esophageal Adenocarcinoma” .

13-May-2014 2:35 PM EDT
Experts to Present Data on New Way to Predict Response to Chemotherapy For Triple-Negative Breast Cancer Patients
University Hospitals Cleveland Medical Center

Researchers from University Hospitals (UH) Case Medical Center’s Seidman Cancer Center will present findings from a study that found the presence of tumor-infiltrating lymphocytes, a type of white blood cell, ahead of treatment may help predict response to platinum-based chemotherapy in women with triple-negative breast cancer. The data are being presented at the 50th American Society for Clinical Oncology (ASCO) Annual Meeting in Chicago. “Triple-negative breast cancers tend to be more aggressive compared to other types of breast cancers, and being able to predict response to therapy could greatly impact treatment decisions and patient outcomes,” says study author Shaveta Vinayak, MD, oncologist at UH Case Medical Center and Assistant Professor at Case Western Reserve University School of Medicine. “Our research shows that the presence of lymphocytes before administering chemotherapy could predict a positive response to platinum-based therapy.”

Released: 15-May-2014 2:00 PM EDT
Neurosurgeon Uses Depth Electrodes for Speech Mapping
University Hospitals Cleveland Medical Center

A neurosurgeon tests if deep brain stimulation electrodes can be used as an alternative to traditional WADA test for identifying brain hemisphere for speech dominance.

Released: 16-May-2014 11:00 AM EDT
Ataluren Phase 3 Trial Results in Nonsense Mutation Cystic Fibrosis Published in the Lancet Respiratory Medicine
University Hospitals Cleveland Medical Center

Results of a Phase 3 study of ataluren in patients with nonsense mutation cystic fibrosis (nmCF) were published in Lancet Respiratory Medicine. Results demonstrated positive trends in both the primary endpoint, lung function as measured by relative change in % predicted FEV1 (forced expiratory volume in one second) and in the secondary outcome measure, rate of pulmonary exacerbations.

Released: 23-May-2014 11:00 AM EDT
Boy Meets Grill (and Loses Weight)
University Hospitals Cleveland Medical Center

Release offers tips on how to make grilling a healthy part of one's diet.

Released: 28-May-2014 3:00 PM EDT
'Fed Up': Simple Answers to a Complex Problem?
University Hospitals Cleveland Medical Center

University Hospitals Case Medical Center Clinical Dietitian Lisa Cimperman comments about new film Fed Up.


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