Released: 21-Jan-1998 12:00 AM EST
FDA APPROVES ROSWELL PARK DISCOVERY
Roswell Park Comprehensive Cancer Center

The U.S. Food and Drug Administration approved the use of Photofrin(r), a light activated drug used in Photodynamic Therapy, for treatment of patients with early-stage lung cancer.

Released: 6-Feb-1998 12:00 AM EST
Regional Cancer Center Consortium Formed to Study Biological Therapy of Cancer
Roswell Park Comprehensive Cancer Center

Roswell Park Cancer Institute will host the first meeting of a Regional Cancer Center Consortium for Biological Therapy of Cancer, February 19-21, in honor of the Institute's Centennial.

Released: 9-May-1998 12:00 AM EDT
Inhaled Cellulosic and Plastic Fibers Found in Human Lung Tissue
Roswell Park Comprehensive Cancer Center

The first report of the discovery of inhaled cellulosic and plastic fibers in human lung tissue has been published by researchers at Roswell Park Cancer Institute in the May, 1998 issue of Cancer Epidemiology, Biomarkers & Prevention. The fibers in the human lung may be bioresistant and biopersistent candidate agents contributing to the risk of lung cancer.

Released: 5-Jun-1998 12:00 AM EDT
State-of-the-Art Detection and Treatment of Early Stage Lung Cancer
Roswell Park Comprehensive Cancer Center

Lung cancer is the most common cause of cancer deaths in North America. Innovative technology at RPCI will enable physicians to detect premalignant and preinvasive neoplastic lesions in the lung and initiate appropriate curative treatments such as surgery, radiation therapy, chemotherapy or in many cases, photodynamic therapy using the photosensitzer, Photofrin.

5-Nov-1998 12:00 AM EST
"Safer Cigarette" Not So Safe
Roswell Park Comprehensive Cancer Center

There is no such thing as a "safe" cigarette, concludes Roswell Park Cancer Institute (RPCI) investigators, whose comprehensive analysis of one "safe cigarette" appears in today's issue of Cancer Epidemiology, Biomarkers & Prevention.

Released: 1-Dec-1998 12:00 AM EST
Wilms' Tumor Research Updates Treatment
Roswell Park Comprehensive Cancer Center

Fewer chemotherapy treatments, less intense side effects and fewer visits to the hospital are on the horizon for some pediatric patients. These are the results of an eight-year clinical trial in patients with Wilms' tumor, a cancer of the kidney most often seen in children, published in today's Journal of Clinical Oncology.

Released: 10-Dec-1998 12:00 AM EST
Project to Develop Edible Plant Vaccine
Roswell Park Comprehensive Cancer Center

A Roswell Park Cancer Institute scientist and Axis Genetics plc., Cambridge, United Kingdom, will collaborate to advance the first edible plant vaccine to protect against hepatitis B virus infection.

Released: 15-Jan-1999 12:00 AM EST
New Treatment Combo for Non-Hodgkins Lymphoma
Roswell Park Comprehensive Cancer Center

A multi-institutional clinical study led by Roswell Park Cancer Institute has demonstrated the safety and effectiveness of a chemoimmunotherapy treatment for patients with non-Hodgkin's lymphoma. The overall response rate was 95% for patients who received treatment with a combination of Rituxan, a monoclonal antibody, and the systemic standard dose chemotherapy regimen used for this disease.

Released: 24-Mar-1999 12:00 AM EST
Roswell Park Cancer Institute Board of Directors Announced
Roswell Park Comprehensive Cancer Center

David C. Hohn, MD, President and CEO, Roswell Park Cancer Institute (RPCI), today announced the formation of the Roswell Park Cancer Institute Corporation (RPCIC) and the composition of the RPCIC Board of Directors under the direction of Board Chairman, Mr. Patrick P. Lee, Chairman and CEO of International Motion Control Inc.

Released: 27-Apr-1999 12:00 AM EDT
Health Effects of Chernobyl Accident after 13 Years
Roswell Park Comprehensive Cancer Center

Researchers from Roswell Park Cancer Institute (RPCI) are part of an international group studying the long-term health effects caused by the destruction of the nuclear power plant in Chernobyl, Ukraine, April 26, 1986, which exposed thousands to radiation and contaminated farmlands in the Ukraine and Belarus.

Released: 11-May-1999 12:00 AM EDT
Global Progress: Breast Cancer Mortality Rates
Roswell Park Comprehensive Cancer Center

The long-term, worldwide trend of increasing breast cancer mortality rates apparently has been reversed in several countries, with significant declines reported in the United States, the United Kingdom and Canada in the 1990s. These are the findings of a study conducted at Roswell Park Cancer Institute and published in the May/June 1999 issue of CA -- A Cancer Journal for Physicians.

Released: 19-May-1999 12:00 AM EDT
Promise for Non-Hodgkin's Lymphoma Drug
Roswell Park Comprehensive Cancer Center

Preliminary results of a pilot and a Phase II study using Rituximab to treat non-Hodgkin's lymphoma were presented at the American Society of Clinical Oncology meeting in Atlanta. These studies show Rituximab to be effective when combined with Fludarabine (a chemotherapy) and when used alone dosed in an extended eight-infusion regimen. Both trials were conducted at Roswell Park Cancer Institute and other cancer centers.

23-Jun-1999 12:00 AM EDT
Genetic Factors Tied to Colorectal Cancer in African Americans
Roswell Park Comprehensive Cancer Center

Novel genetic factors contribute to the incidence of colorectal cancer among a percentage of African-Americans, according to the results of a pioneering study conducted by a research team headed by Thomas K. Weber, MD, FACS, of the Division of Surgery, Roswell Park Cancer Institute. Their report will appear in the June 23, 1999 edition of the Journal of the American Medical Association.

Released: 8-Jul-1999 12:00 AM EDT
Human Trials for Oral Hepatitis B Plant Vaccine
Roswell Park Comprehensive Cancer Center

Roswell Park Cancer Institute (RPCI) and the Boyce Thompson Institute at Cornell University announced that clinical trials will begin today, Wednesday, July 7, 1999, at RPCI, to test the safety and immunogenicity of the world's first potential oral vaccine against the hepatitis B virus.

Released: 12-Aug-1999 12:00 AM EDT
Gelsolin and Earlier Breast Cancer Diagnosis, Treatment
Roswell Park Comprehensive Cancer Center

Roswell Park Cancer Institute scientists have found that the level of gelsolin, a protein responsible for maintaining actin filaments that are needed for healthy cells, may be of diagnostic and therapeutic value for breast cancer.

Released: 13-Aug-1999 12:00 AM EDT
Women at High Risk for Breast Cancer Offered Breast MRI Study
Roswell Park Comprehensive Cancer Center

Roswell Park Cancer Institute is participating in a pilot study to investigate the value of magnetic resonance imaging for the detection of breast cancer in women who are at high risk for the disease. The Consortium received a $6 million National Cancer Institute grant for breast MRI clinical trials.

Released: 2-Oct-1999 12:00 AM EDT
Roswell Park Researchers Study 15-Year Survivors of Childhood Cancer
Roswell Park Comprehensive Cancer Center

The first study to evaluate the impact of cardiac disease and second malignant neoplasms on late mortality and to identify risk factors for late mortality among 15-year survivors of cancer diagnosed during childhood or adolescence has concluded that survivors who relapsed during the 15-year period have excess mortality.

21-Dec-1999 12:00 AM EST
Genomic Chaos, Cellular Evolution, Colorectal Cancer
Roswell Park Comprehensive Cancer Center

Research on colorectal cancer tumors and premalignant polyps, published in the December 21 issue of the Proceedings of the National Academy of Sciences, show that cancer arises from a decade or more of cellular changes.

Released: 15-Jan-2000 12:00 AM EST
Gilda Radner Courage Award
Roswell Park Comprehensive Cancer Center

Amy S. Langer, Executive Director of the National Alliance of Breast Cancer Organizations, will receive the Gilda Radner Courage Award from the Roswell Park Alliance Community Fund-Raising Board at its 10th Annual All Star Night, Saturday, January 22, 2000.

Released: 21-Jan-2000 12:00 AM EST
Roswell Park Cancer Institute Appointments
Roswell Park Comprehensive Cancer Center

Roswell Park Cancer Institute Corporation has announced two administrative appointments within the Division of Head and Neck Surgical Oncology/Plastic and Reconstructive Surgery.

Released: 1-Mar-2000 12:00 AM EST
Aggressive Tobacco Control Measures and Adult Smoking
Roswell Park Comprehensive Cancer Center

The lessons from California's aggressive tobacco control intervention program, which has resulted in a continuing decline in adult smoking, may help to decrease adult smoking throughout the U.S., according to a study in the March American Journal of Public Health.

28-Mar-2000 12:00 AM EST
Malignant Neoplasms, Pediatric Hodgkin's Disease
Roswell Park Comprehensive Cancer Center

Childhood survivors of Hodgkin's disease have a substantial risk for second malignant neoplasms, according to research published in today's Journal of Clinical Oncology.

Released: 5-Aug-2000 12:00 AM EDT
RPCI Offers Radio Frequency Ablation to Treat Tumors
Roswell Park Comprehensive Cancer Center

Radio frequency ablation is being offered as a treatment option for patients with inoperable tumors by Roswell Park Cancer Institute. RFA may also be used in special cases to treat esophageal, gastrointestinal, testicular, ovarian, neuroendocrine and breast cancers.

Released: 8-Aug-2000 12:00 AM EDT
Uterine Fibroid Embolization May Avoid Hysterectomy
Roswell Park Comprehensive Cancer Center

With the addition of a new procedure called uterine fibroid embolization, RPCI will expand its services to include treatment of benign fibroid tumors. UFE may preserve fertility by avoiding hysterectomy, particularly in young women with this condition.

Released: 29-Aug-2000 12:00 AM EDT
Symposium on New Leads in Cancer Therapeutics
Roswell Park Comprehensive Cancer Center

Roswell Park Cancer Institute (RPCI) will host a symposium titled, "Molecular Sites of Intervention for Cancer Therapeutics," October 12-13, in Buffalo, NY, to describe and discuss new approaches to the development of cancer therapeutics.

30-Nov-2000 12:00 AM EST
Early Detection and Screening for Lung Cancer
Roswell Park Comprehensive Cancer Center

There is a strong push to find methods that may improve survival of Lung cancer by diagnosing the disease at an earlier, presumably more curable, stage. However, whether early detection results in a higher number of cured patients remains unclear. (NEJM, 11-30-00)

Released: 30-Dec-2000 12:00 AM EST
Increase of Brain Tumors in New York State
Roswell Park Comprehensive Cancer Center

The "not so good news" from a recent study conducted at Roswell Park Cancer Institute is that the incidence rates for two forms of common brain tumors - glioblastoma multiforme (GBM) and anaplastic astrocytoma - have increased in New York State between 1976 and 1995. The ìgood newsî is that the study may have revealed clues to the origins of GBM; the most common of these tumors. (Journal of Neurosurgery, 12-00)

Released: 23-Feb-2001 12:00 AM EST
Effect of Age and Other Illnesses on Patients with Breast Cancer
Roswell Park Comprehensive Cancer Center

Current treatment options may not be adequately meeting the needs of post-menopausal women who develop breast cancer. (JAMA, 2-21-01).

Released: 7-Mar-2001 12:00 AM EST
Unique Program Highlighted at NCCN Conference
Roswell Park Comprehensive Cancer Center

A unique pilot initiative created at Roswell Park Cancer Institute was highlighted at the Sixth Annual Conference of the National Comprehensive Cancer Network: "Practice Guidelines and Outcomes Data in Oncology."

Released: 10-Mar-2001 12:00 AM EST
Melanoma Treatment Evaluated
Roswell Park Comprehensive Cancer Center

Roswell Park Cancer Institute (RPCI) is participating in a multi-center clinical trial to evaluate the benefits and side effects of isolated hyperthermic limb perfusion and melphalan, with or without tumor necrosis factor for patients with advanced melanoma in one of their limbs.

Released: 1-Jun-2002 12:00 AM EDT
Monitoring Pregnancy Key After Wilms Treatment
Roswell Park Comprehensive Cancer Center

Women who received radiation for a certain type of childhood cancer are at increased risk for complications during pregnancy, and therefore should be carefully assessed and closely monitored by their obstetricians.

Released: 26-Jul-2002 12:00 AM EDT
National Patient Care Model: Buffalo Niagara Prostate Cancer Consortium
Roswell Park Comprehensive Cancer Center

The Buffalo Niagara Prostate Cancer Consortium, located at Roswell Park Cancer Institute, is recognized as a national model for patient care by the National Comprehensive Cancer Network and the Oncology Roundtable of the Advisory Board Company. This innovative collaboration, a first in the nation, includes community urologists, academic institutions, patient support groups, insurance carriers and RPCI.

Released: 1-Aug-2002 12:00 AM EDT
New Skin Cancer Treatment
Roswell Park Comprehensive Cancer Center

Roswell Park Cancer Institute has initiated two Phase II clinical trials to evaluate the safety and effectiveness of photodynamic therapy using a newly-developed topical photosensitizing cream, aminolevulinic acid (ALA), for the treatment of various types of skin cancer and actinic keratosis, a precancerous condition.

Released: 16-Aug-2002 12:00 AM EDT
Physician Practice on Breast Cancer Outcomes Measured
Roswell Park Comprehensive Cancer Center

A surprising number of variations exist in the way physicians diagnose and treat mammogram-detected breast cancer, according to a study. Researchers from Roswell Park Cancer Institute (RPCI) and Independent Health examined claims data to determine if practice volume impacted breast cancer outcomes.

Released: 24-Oct-2002 12:00 AM EDT
Conjugated Linoleic Acid Slows Tumor Growth
Roswell Park Comprehensive Cancer Center

Conjugated linoleic acid (CLA) decreases blood vessel formation --slowing tumor growth -- according to the results of a Roswell Park Cancer Institute study.

Released: 18-Jun-2003 12:00 AM EDT
Follow-Up Therapies Needed for Patients with Pancreatic Cancer
Roswell Park Comprehensive Cancer Center

New, more effective follow-up treatments are needed to manage patients after surgery for pancreatic cancer because only a small percentage of these patients benefit from the current "standard" adjuvant therapy -- chemoradiation.

Released: 8-Aug-2003 9:00 AM EDT
FDA Approves Roswell Park Discovery for Barrett's Esophagus
Roswell Park Comprehensive Cancer Center

Roswell Park Cancer Institute announced this week that the FDA has approved PHOTOFRIN photodynamic therapy in the treatment of high-grade dysplasia associated with Barrett's esophagus.

Released: 3-Sep-2003 4:00 PM EDT
Racial Differences in Men with Prostate Cancer Examined
Roswell Park Comprehensive Cancer Center

African-American men are known to be at greater risk for developing and dying from prostate cancer. Racial differences in the androgenic stimulation of the prostate could be the reason prostate cancer occurs at a younger age and progresses more rapidly in African than Caucasian Americans.

Released: 19-Sep-2003 9:00 AM EDT
Roswell Park Grant Awards Top $40.9 Million
Roswell Park Comprehensive Cancer Center

Since January 2003, 36 faculty members of Roswell Park Cancer Institute (RPCI) have competed successfully for 43 grants which have a total value of $40.9 million and a first year value of $11.2 million. These grants include two prestigious program project grants awarded by the National Cancer Institute.

10-Oct-2003 1:20 PM EDT
Study Suggests Common Use of Investigational Breast Cancer Test
Roswell Park Comprehensive Cancer Center

A new study suggests that surgeons are routinely performing an investigational procedure called sentinel node biopsy on women with early-stage breast cancer, which, the investigators say, may be affecting the generalizability of ongoing trials of the procedure.

Released: 20-Jan-2004 2:50 PM EST
Biological Therapy Symposium
Roswell Park Comprehensive Cancer Center

Roswell Park Cancer Institute (RPCI) will host the 7th annual meeting of the Regional Cancer Center Consortium for the Biological Therapy of Cancer, February 26-28, in the Research Studies Center, RPCI, Elm & Carlton Streets, Buffalo, NY.

Released: 13-Feb-2004 1:20 PM EST
New View of Recurrent Prostate Cancer
Roswell Park Comprehensive Cancer Center

Results of a study support taking a revised view of prostate cancer and how best to treat it. Almost all advanced prostate cancer responds well at first to androgen deprivation therapy but the cancer recurs with a poor prognosis. This study suggests that these cases might need to be managed in a different way.

11-Feb-2005 3:50 PM EST
Roswell Park Study Evaluates Oral Hepatitis B Vaccine
Roswell Park Comprehensive Cancer Center

An oral vaccine administered in genetically engineered potatoes shows promise against the Hepatitis B Virus (HBV). The vaccine, which consists of only one protein from the virus, may be safer than other oral vaccines that use weakened living viruses.

Released: 17-May-2005 11:00 AM EDT
Don't Forget to Protect Skin from the Sun
Roswell Park Comprehensive Cancer Center

This release offers an overview of skin cancer, how it develops and methods to treat it, including a non-surgical alternative called Photodynamic Therapy.

Released: 1-Jun-2005 12:20 PM EDT
Gilda Radner Familial Ovarian Cancer Registry Celebrates 25th Anniversary
Roswell Park Comprehensive Cancer Center

The Gilda Radner Familial Ovarian Cancer Registry, established in 1981 to track families who have included at least two first degree relatives diagnosed with ovarian cancer, is celebrating its 25th anniversary.

Released: 21-Dec-2005 1:40 PM EST
Roswell Park Research Presented at National Hematology Meeting
Roswell Park Comprehensive Cancer Center

Scientists from the Department of Medicine, Roswell Park Cancer Institute, presented preliminary laboratory and clinical results of new therapies for hematologic cancers earlier this month at the 47th Annual Meeting of the American Society of Hematology, Atlanta, GA.

31-Mar-2006 2:00 PM EST
Association of Dietary Lignan Intake with Breast Cancer Risk
Roswell Park Comprehensive Cancer Center

Susan McCann, PhD, will discuss the findings of her research in an oral presentation, "Dietary Lignan Intakes and Risk of Breast Cancer by Tumor Estrogen Receptor Status," at the 2006 annual meeting of the American Association for Cancer Research (AACR), Washington, DC.

1-Apr-2006 3:15 PM EST
Design Improvements In Nanodevices Means More Precise Treatment Targeting
Roswell Park Comprehensive Cancer Center

Changing the size and surface charge of nanodevices significantly alters the way the nanodevices are taken up by organs and tissues in the body. This should allow for better targeting of treatments, according to scientists from the laboratory of Mohamed Khan, MD, PhD, and Lajos Balogh, PhD.

1-Apr-2006 3:20 PM EST
Higher Intakes of Tea and Milk May Reduce Risk of AML in Women
Roswell Park Comprehensive Cancer Center

A diet with higher intakes of milk and tea may lower women's risk of developing acute myeloid leukemia (AML), according to scientists from the laboratory of Susan McCann, PhD, Division of Cancer Prevention & Population Sciences, Roswell Park Cancer Institute.

1-Apr-2006 3:40 PM EST
New Drug May Offer Double Benefits for Patients with Non-Hodgkin Lymphoma
Roswell Park Comprehensive Cancer Center

A new drug may boost the effectiveness of a widely used treatment for patients with non-Hodgkin lymphoma (NHL), while simultaneously overcoming drug resistance in those patients. That conclusion is based on a study conducted by scientists from the laboratory of Myron Czuczman, MD, Department of Medicine, Roswell Park Cancer Institute.


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