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Scientists Find Possible Achilles Heel of Treatment Resistant Cancers

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Scientists identify two signaling proteins in cancer cells that make them resistant to chemotherapy, and show that blocking the proteins along with chemotherapy eliminate human leukemia in mouse models. Reporting results March 20 in Nature Medicine,...
16-Mar-2017 12:00 PM EDT Add to Favorites

Poison Prevention Awareness Week Kicks Off on March 19

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The Cincinnati Drug and Poison Information Center (DPIC) at Cincinnati Children’s Hospital Medical Center is a 24-hour emergency and information telephone service for anyone with concerns about poisons or drugs. In 2016, DPIC received more than...
19-Mar-2017 12:05 AM EDT Add to Favorites

Study Identifies Molecular Clues for Age-Related Intestinal Issues

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Intestinal stem cells rejuvenate daily so bowels will stay healthy and function normally, but a new study in Cell Reports suggests they also age along with people and lose their regenerative capacity. Reporting their data online March 14,...
9-Mar-2017 10:00 AM EST Add to Favorites

Study Describes Potential Clinical Test and Treatment for Preterm Birth

Scientists identified a molecular driver of inflammation that may finally answer a key question about what causes mild systemic prenatal infections to trigger preterm birth. The finding is an important step to developing a treatment or clinical test...
7-Mar-2017 8:45 AM EST Add to Favorites

Scientists Wage Fight Against Aging Bone Marrow Stem Cell Niche

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As people get older so do the hematopoietic stem cells (HSCs) that form their blood, creating an increased risk for compromised immunity and certain blood cancers. Now researchers are reporting in the scientific journal EMBO that the bone marrow...
1-Mar-2017 2:00 PM EST Add to Favorites

Nature Study Suggests New Therapy for Gaucher Disease

Scientists propose in Nature blocking a molecule that drives inflammation and organ damage in Gaucher and maybe other lysosomal storage diseases as a possible treatment with fewer risks and lower costs than current therapies. Reporting their data...
21-Feb-2017 11:00 AM EST Add to Favorites

Doctors Treat Deadly Cancerous Disorders with Gene-Guided, Targeted Therapy

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Genomic testing of biopsies from patients with deadly, treatment-resistant cancerous blood syndromes called histiocytoses allowed doctors to identify genes fueling the ailments and use targeted molecular drugs to successfully treat them. Researchers...
16-Feb-2017 10:30 AM EST Add to Favorites

Excessive Antibiotic Use in Newborns Can Permanently Damage Lungs’ Defenses

Doctors have long understood that antibiotics that protect infants from infection also can disrupt the normal growth of their gut bacteria. However, a new study reveals that the consequences of routine antibiotic use may be deeper and longer lasting...
7-Feb-2017 9:45 AM EST Add to Favorites

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