Researchers have long had reason to hope that blocking the flow of calcium into the mitochondria of heart and brain cells could be one way to prevent damage caused by heart attacks and strokes. But in a study of mice engineered to lack a key calcium...
6-Jul-2015 3:00 PM EDT
New research suggests that a molecule commonly found “decorating” brain cells in higher animals, including humans, may affect brain structure. The study showed that small changes made in how sialic acid attaches to cell surfaces can cause...
6-Jul-2015 9:05 AM EDT
For cell division to be successful, pairs of chromosomes have to line up just right before being swept into their new cells, like the opening of a theater curtain. They accomplish this feat in part thanks to structures called centrioles that provide...
30-Jun-2015 11:15 AM EDT
Animal Study Shows Experimental Drug Combined with Standard Chemo May Shrink Treatment-Resistant Ovarian Cancers
Working in cell cultures and mice, researchers at Johns Hopkins have found that an experimental drug called fostamatinib combined with the chemotherapy drug paclitaxel may overcome ovarian cancer cells’ resistance to paclitaxel.
1-Jul-2015 9:00 AM EDT
An analysis of the results of more than 16,000 brain and spine surgeries suggests patients have nothing to fear from having residents — physicians-in-training — assist in those operations. The contributions of residents, who work under the...
29-Jun-2015 9:05 AM EDT
On the hunt for better cancer screening tests, Johns Hopkins scientists led a proof of principle study that successfully identified tumor DNA shed into the blood and saliva of 93 patients with head and neck cancer. A report on the findings is...
24-Jun-2015 5:50 PM EDT
In a genome-wide association study believed to be the largest of its kind, Johns Hopkins researchers have uncovered four regions in the human genome where changes may increase the risk of pancreatic cancer.
24-Jun-2015 5:40 PM EDT
Working with heart muscle cells from diabetic rats, scientists at Johns Hopkins have located what they say is the epicenter of mischief wreaked by too much blood sugar and used a sugar-gobbling enzyme to restore normal function in the...
24-Jun-2015 5:30 PM EDT
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