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Heart Attack Treatment Hypothesis ‘Busted’

Researchers have long had reason to hope that blocking the flow of calcium into the mitochondria of heart and brain cells could be one way to prevent damage caused by heart attacks and strokes. But in a study of mice engineered to lack a key calcium...
6-Jul-2015 3:00 PM EDT

‘Decorative’ Molecule on Brain Cells Affects Motor Skills, Learning and Hyperactivity

New research suggests that a molecule commonly found “decorating” brain cells in higher animals, including humans, may affect brain structure. The study showed that small changes made in how sialic acid attaches to cell surfaces can cause...
6-Jul-2015 9:05 AM EDT

Cellular Sentinel Prevents Cell Division When the Right Machinery Is Not in Place

For cell division to be successful, pairs of chromosomes have to line up just right before being swept into their new cells, like the opening of a theater curtain. They accomplish this feat in part thanks to structures called centrioles that provide...
30-Jun-2015 11:15 AM EDT

Animal Study Shows Experimental Drug Combined with Standard Chemo May Shrink Treatment-Resistant Ovarian Cancers

Working in cell cultures and mice, researchers at Johns Hopkins have found that an experimental drug called fostamatinib combined with the chemotherapy drug paclitaxel may overcome ovarian cancer cells’ resistance to paclitaxel.
1-Jul-2015 9:00 AM EDT

Brain and Spine Surgery No More Risky When Physicians-in-Training Participate

An analysis of the results of more than 16,000 brain and spine surgeries suggests patients have nothing to fear from having residents — physicians-in-training — assist in those operations. The contributions of residents, who work under the...
29-Jun-2015 9:05 AM EDT

DNA Shed from Head and Neck Tumors Detected in Blood and Saliva

On the hunt for better cancer screening tests, Johns Hopkins scientists led a proof of principle study that successfully identified tumor DNA shed into the blood and saliva of 93 patients with head and neck cancer. A report on the findings is...
24-Jun-2015 5:50 PM EDT

Study Identifies Multiple Genetic Changes Linked to Increased Pancreatic Cancer Risk

In a genome-wide association study believed to be the largest of its kind, Johns Hopkins researchers have uncovered four regions in the human genome where changes may increase the risk of pancreatic cancer.
24-Jun-2015 5:40 PM EDT

Johns Hopkins Scientists Restore Normal Function in Heart Muscle Cells of Diabetic Rats

Working with heart muscle cells from diabetic rats, scientists at Johns Hopkins have located what they say is the epicenter of mischief wreaked by too much blood sugar and used a sugar-gobbling enzyme to restore normal function in the...
24-Jun-2015 5:30 PM EDT

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