ENBREL (etanercept), one of the new class of drugs used to treat rheumatoid arthritis in adults, is also effective in children suffering from juvenile rheumatoid arthritis (JRA), according to the first-ever study of a biologic for treatment of JRA.
The chance of becoming obese in adulthood can be predicted based on the age at which a child is thinnest, according to a study by a physician at Children's Hospital Medical Center of Cincinnati.
Scientists at Children's Hospital Medical Center of Cincinnati have discovered a major mechanism by which bacteria protect themselves against the human immune response - a discovery that opens the door for development of a new class of antibiotics to fight infection.
Federal policies regarding residential lead poisoning favor the lead industry or economic concerns at the expense of children's health, according to an article by a physician from Children's Hospital Medical Center of Cincinnati in the September 11 edition of the journal Science.
A reduction in length of stay for newborns insured by Medicaid appears to be a safe practice - if post-discharge care is well-coordinated, according to a Children's Hospital Medical Center of Cincinnati study published in the September 22/29 edition of The Journal of the American Medical Association (JAMA).
It's more than physical factors that affect teenage health. Social factors, particularly parents' education, occupation, and household income, also play an important role in susceptibility to adolescent disease, says a study in the American Journal of Public Health.
The discovery of a critical pathway that plays a key role in the development of food allergy could lead rapidly to clinical trials of new drugs that would block the protein eotaxin, thereby preventing allergic reactions in the gastrointestinal tract (Proceedings of the National Academy of Sciences, 6-6-00).
It's commonly thought that teen depression can lead to cigarette smoking, but a new study, published in the October edition of Pediatrics, shows it's the smoking that increases the risk of depression. (Pediatrics, 10-00)
A Children's Hospital Medical Center of Cincinnati study indicates that most efforts to prevent obesity in childhood aren't likely to be successful. The study shows that only 21 percent of mothers of overweight preschoolers feel their children are overweight.
A new discovery may have significant implications for children with a eosinophilic esophagitis, a fast-growing new disease whose symptoms mimic gastroesophageal reflux, and for adults with reflux who are not being helped by currently available medications.
A new study at the Children's Hospital Medical Center of Cincinnati shows that some children who get computed tomography scans receive doses of radiation at strengths at least five times greater than necessary. (American Journal of Roentgenology, 2-01)
More than half a million children in the United States under the age of 6 with asthma would not have the disease if risk factors were removed from the home. (Pediatrics, 3-01)
A new Cincinnati Children's Hospital Medical Center study shows that children who eat meals in front of the television spend more time watching TV -- far more time than it takes them to eat their meals. The discovery is significant because excessive TV watching has been linked to obesity.
The most comprehensive national study to date of smoking before, during and after pregnancy shows that women with less education are more likely to smoke before delivery, less likely to quit during pregnancy and more likely to relapse after delivery.
A new discovery by a researcher at Cincinnati Children's Hospital Medical Center could dramatically reduce the number of liver transplants in children and lead to new treatments for biliary atresia, the most common reason for pediatric liver transplant.
A new Cincinnati Children's Hospital Medical Center study suggests that certain abnormalities of the heart are more common in obese children than in children of normal weight.
Children who frequently change schools are more likely than those who don"št to have behavioral health problems, according to a new Cincinnati Children's Hospital Medical Center study.
A new study indicates that depression may play a significant role in hindering the ability of mothers to care for their children. 76 percent of those who screen positive for depression reported that their depression "made it difficult to care for their children."
Two new studies by researchers at Cincinnati Children's Hospital Medical Center find that the home is the single most common location for children in the United States to be injured.
In laboratory studies, researchers have successfully treated the most common malignant abdominal tumor of childhood: neuroblastoma tumors. Researchers successfully treated the tumor in mouse models by administering a treatment based on a weakened version of the herpes simplex virus.
Researchers have found that a single mutation in a recently discovered Parkinson's disease gene is responsible for 5 percent of inherited Parkinson's disease cases. The finding opens the door to the possibility of genetic screening for the LRRK2 gene mutation, which is believed to be the most common genetic cause of inherited Parkinson's disease identified to date.
Children who suffer from acute asthma attacks share a genetic profile that appears to be unique to these children, according to a new study. The discovery opens the door to the possibility of designing treatments specifically tailored to children who suffer from the severest forms of asthma.
A new study indicates that cognitive and behavioral problems that underlie Attention Deficit Hyperactivity Disorder (ADHD) are due to a complex underplay of genes and the environment.
Cincinnati Children's Hospital Medical Center today announced the publication of pioneering research identifying the crucial role and novel mechanism of action of the protein RhoH GTPase in the development and activation of cells critical to the immune system. The findings, along with other studies, suggest that RhoH GTPase may provide a target for therapeutic intervention in some types of leukemia.
A study authored by a researcher at Cincinnati Children's Hospital Medical Center reports on work to develop standardized criteria to detect bone mass deficiencies in children with chronic diseases.
Many children return to school sports, such as soccer, football, cross-country and volleyball in late-July or early-August. Jon Divine, M.D., director of Sports Medicine at Cincinnati Children's Hospital Medical Center, says it's most important for children to be in shape even before showing up for the first day of practice or tryouts to reduce the risk of injury.
The start of the school year also means the return of school lunches, and the choice of brown-bagging or eating in the cafeteria. A nutritionist at Cincinnati Children's Hospital Medical Center says that it may seem contrary to perception, but a lunch from home may be the better choice, nutritionally.
"Taking time to talk with and listen to children about the upcoming school year is one of the best ways parents can help them make the transition to school life," says David Smith, Ph.D., child psychologist at Cincinnati Children's Hospital Medical Center. Dr. Smith advises parents to begin talking about school a couple weeks before it starts, and to listen closely for their children's fears or concerns.
Cincinnati Children's Hospital Medical Center has many pedestrian, bus riding and home safety tips to help parents prepare to send their children back to school.
A consortium of researchers headed by Cincinnati Children's Hospital Medical Center has discovered a gene expression pattern that could lead to improved diagnosis and treatment of pediatric septic shock.
Experts estimate that food allergy occurs in six to eight percent of children four years of age or under, and in four percent of adults. In recent years, it was reported that an estimated 29,000 people go to US emergency rooms each year as a result of allergic reactions to food. Parents whose children have food allergies need to be aware of how to protect their children from having allergic reactions when Trick-or-Treating.
Hypoplastic Left Heart Syndrome (HLHS), a severe cardiovascular malformation that is difficult to treat and often lethal, is caused primarily by genetic factors, according to a new study by researchers at Cincinnati Children's Hospital Medical Center.
Researchers at Cincinnati Children's suggest that therapies designed to interrupt the localized interaction of inflammatory cells and the blood clotting protein, fibrin, may help arthritis patients.
Improving health and nutrition in undernourished children is correlated with less absenteeism, more grades completed and better performance on tests. Good nutrition also improves mental and behavioral performance. Eating well everyday is good insurance for parents that children arrive to school ready to learn.
On average16 school-age pedestrians are killed by school transportation vehicles (school buses and non-school bus vehicles used as school buses) each year, and five are killed by other vehicles involved in school bus-related crashes. More school-age pedestrians are killed in the afternoon than in the morning. A Cincinnati Children's expert offers tips to parents for keeping their kids safe when they return to school.
In May 2002, the U.S. Consumer Product Safety Commission reported backpack related injuries sent almost 6000 students each year to emergency rooms. The American Academy of Orthopedics stated that backpack injury is a significant problem for children.
"Taking time to talk with and listen to children about the upcoming school year is one of the best ways parents can help them make the transition to school life," says David Smith, Ph.D., clinical child psychologist in the Division of Developmental and Behavioral Pediatrics of Cincinnati Children's Hospital Medical Center.
Many children return to school sports, such as soccer, football, cross-country and volleyball in late-July or early-August. Jon Divine, M.D., director of Sports Medicine at Cincinnati Children's Hospital Medical Center, says it's most important for children to be in shape even before showing up for the first day of practice or tryouts to reduce the risk of injury.
With summer ending and school underway, parents are transitioning from hearing their children moan about not being able to swim everyday, to their child complaining about homework, their new teachers or being in a different class than their friends. Many parents also begin to hear more complaints of tummy aches and headaches as a result of returning back to school. The psychological term for school-induced illnesses a child may develop when he or she is trying to dodge school is School Avoidance, or School Refusal. Symptoms include nausea, fatigue, headaches and abdominal pain.
While Halloween can be a fun holiday for children who Trick-or-Treat, the night can indeed be a scary experience for any of the three million youth who suffer from food allergy. Experts estimate that food allergy occurs in six to eight percent of children four years of age or under, and in four percent of adults. In recent years, it was reported that an estimated 29,000 people go to US emergency rooms each year as a result of allergic reactions to food.
The holiday season is usually a time of joy but it also brings the potential for poisonings, according to the Drug and Poison Information Center (DPIC), a service of Cincinnati Children's Hospital Medical Center. The following information includes safety hazards and precautionary ways to ensure that families have a safe holiday season.
With the excitement of the holidays, parents and relatives eagerly purchase the hottest toys and latest items for their children. But it's during the hustle and bustle of the season that many fail to buy age appropriate gifts for their children and they tend to disregard warnings on these toys and gifts when it comes to ensuring safety.
A Cincinnati Children's Hospital Medical Center study shows that a growing number of adults know about the potential risk of swallowing magnets, but medical complications from magnets continue to be extensive worldwide and throughout childhood.
Researchers led by Cincinnati Children's Hospital Medical Center identified an apparent population of cancer stem cells for neuroblastoma, then used a reprogrammed herpes virus to block tumor formation in mice by targeting and killing the cells.
Screening for mutations in a gene that helps the body metabolize a kidney transplant anti-rejection drug may predict which children are at higher risk for toxic side effects, according to new research in Clinical Pharmacology and Therapeutics.
Researchers have discovered a gene that modifies the severity of lung disease in people with the lethal genetic condition, cystic fibrosis, pointing to possible new targets for treatment, according to a new study in Nature.
Research in Public Library of Science (PLoS) Pathogens appears to solve a long standing medical mystery by identifying a viral protein, VP16, as the molecular key that prompts herpes simplex virus (HSV) to exit latency and cause recurrent disease.
More than 45,000 infants and children in the United States are hospitalized each year for urinary tract infections, but a new study reveals significant variability across hospitals in treatment and outcomes.
The strong preference kids with autism have for certain foods places them at risk for nutritional deficiencies because their diets lack sufficient variety, according to research from Cincinnati Children's Hospital Medical Center at this year's Pediatric Academic Societies meeting in Baltimore.