Released: 10-Nov-1998 12:00 AM EST
New Drug Dramatic Advancement for Treating JRA
Cincinnati Children's Hospital Medical Center

ENBREL (etanercept), one of the new class of drugs used to treat rheumatoid arthritis in adults, is also effective in children suffering from juvenile rheumatoid arthritis (JRA), according to the first-ever study of a biologic for treatment of JRA.

Released: 20-Feb-1998 12:00 AM EST
Early Changes in Childhood Body Fat Predict Adult Obesity
Cincinnati Children's Hospital Medical Center

The chance of becoming obese in adulthood can be predicted based on the age at which a child is thinnest, according to a study by a physician at Children's Hospital Medical Center of Cincinnati.

31-Aug-1998 12:00 AM EDT
How Bacteria Protect Themselves Against Immune Response
Cincinnati Children's Hospital Medical Center

Scientists at Children's Hospital Medical Center of Cincinnati have discovered a major mechanism by which bacteria protect themselves against the human immune response - a discovery that opens the door for development of a new class of antibiotics to fight infection.

10-Sep-1998 12:00 AM EDT
Criticism of Federal Policy Regarding Lead Exposure and Children's Health
Cincinnati Children's Hospital Medical Center

Federal policies regarding residential lead poisoning favor the lead industry or economic concerns at the expense of children's health, according to an article by a physician from Children's Hospital Medical Center of Cincinnati in the September 11 edition of the journal Science.

22-Sep-1999 12:00 AM EDT
Early Discharge Appears Safe for Medicaid Newborns
Cincinnati Children's Hospital Medical Center

A reduction in length of stay for newborns insured by Medicaid appears to be a safe practice - if post-discharge care is well-coordinated, according to a Children's Hospital Medical Center of Cincinnati study published in the September 22/29 edition of The Journal of the American Medical Association (JAMA).

1-Oct-1999 12:00 AM EDT
Parents' Social Status Key Role in Teenage Health
Cincinnati Children's Hospital Medical Center

It's more than physical factors that affect teenage health. Social factors, particularly parents' education, occupation, and household income, also play an important role in susceptibility to adolescent disease, says a study in the American Journal of Public Health.

6-Jun-2000 12:00 AM EDT
Critical Food Allergy Pathway
Cincinnati Children's Hospital Medical Center

The discovery of a critical pathway that plays a key role in the development of food allergy could lead rapidly to clinical trials of new drugs that would block the protein eotaxin, thereby preventing allergic reactions in the gastrointestinal tract (Proceedings of the National Academy of Sciences, 6-6-00).

3-Oct-2000 12:00 AM EDT
Study Links Teen Smoking to Symptoms of Depression
Cincinnati Children's Hospital Medical Center

It's commonly thought that teen depression can lead to cigarette smoking, but a new study, published in the October edition of Pediatrics, shows it's the smoking that increases the risk of depression. (Pediatrics, 10-00)

5-Dec-2000 12:00 AM EST
Moms Fail to Recognize Obesity in Their Preschoolers
Cincinnati Children's Hospital Medical Center

A Children's Hospital Medical Center of Cincinnati study indicates that most efforts to prevent obesity in childhood aren't likely to be successful. The study shows that only 21 percent of mothers of overweight preschoolers feel their children are overweight.

28-Dec-2000 12:00 AM EST
Allergy/Reflux Link Uncovered
Cincinnati Children's Hospital Medical Center

A new discovery may have significant implications for children with a eosinophilic esophagitis, a fast-growing new disease whose symptoms mimic gastroesophageal reflux, and for adults with reflux who are not being helped by currently available medications.

23-Jan-2001 12:00 AM EST
Children Getting Too Much Radiation From CT Scans
Cincinnati Children's Hospital Medical Center

A new study at the Children's Hospital Medical Center of Cincinnati shows that some children who get computed tomography scans receive doses of radiation at strengths at least five times greater than necessary. (American Journal of Roentgenology, 2-01)

6-Mar-2001 12:00 AM EST
Elimination of Household Allergens and Pollutants Could Reduce Asthma
Cincinnati Children's Hospital Medical Center

More than half a million children in the United States under the age of 6 with asthma would not have the disease if risk factors were removed from the home. (Pediatrics, 3-01)

15-Jun-2002 12:00 AM EDT
Study Warns of Eating Meals in Front of TV
Cincinnati Children's Hospital Medical Center

A new Cincinnati Children's Hospital Medical Center study shows that children who eat meals in front of the television spend more time watching TV -- far more time than it takes them to eat their meals. The discovery is significant because excessive TV watching has been linked to obesity.

30-Oct-2002 12:00 AM EST
Education Strongest Predictor of Smoking
Cincinnati Children's Hospital Medical Center

The most comprehensive national study to date of smoking before, during and after pregnancy shows that women with less education are more likely to smoke before delivery, less likely to quit during pregnancy and more likely to relapse after delivery.

22-Nov-2002 12:00 AM EST
Discovery May Dramatically Reduce Liver Transplants in Children
Cincinnati Children's Hospital Medical Center

A new discovery by a researcher at Cincinnati Children's Hospital Medical Center could dramatically reduce the number of liver transplants in children and lead to new treatments for biliary atresia, the most common reason for pediatric liver transplant.

1-Apr-2003 12:00 AM EST
Heart Abnormalities in Obese Children
Cincinnati Children's Hospital Medical Center

A new Cincinnati Children's Hospital Medical Center study suggests that certain abnormalities of the heart are more common in obese children than in children of normal weight.

5-May-2003 12:00 AM EDT
Frequent School Changes Linked to Behavior Problems
Cincinnati Children's Hospital Medical Center

Children who frequently change schools are more likely than those who don"št to have behavioral health problems, according to a new Cincinnati Children's Hospital Medical Center study.

4-May-2003 12:00 AM EDT
Depression Hampers Mothers' Ability to Care for Children
Cincinnati Children's Hospital Medical Center

A new study indicates that depression may play a significant role in hindering the ability of mothers to care for their children. 76 percent of those who screen positive for depression reported that their depression "made it difficult to care for their children."

6-May-2003 12:00 AM EDT
Home Environment Can Be Hazardous to Children's Health
Cincinnati Children's Hospital Medical Center

Two new studies by researchers at Cincinnati Children's Hospital Medical Center find that the home is the single most common location for children in the United States to be injured.

Released: 1-Dec-2004 9:20 AM EST
Herpes Virus Offers New Hope in Curing Cancer
Cincinnati Children's Hospital Medical Center

In laboratory studies, researchers have successfully treated the most common malignant abdominal tumor of childhood: neuroblastoma tumors. Researchers successfully treated the tumor in mouse models by administering a treatment based on a weakened version of the herpes simplex virus.

14-Jan-2005 10:00 AM EST
Most Common Genetic Cause of Parkinson's Disease Identified
Cincinnati Children's Hospital Medical Center

Researchers have found that a single mutation in a recently discovered Parkinson's disease gene is responsible for 5 percent of inherited Parkinson's disease cases. The finding opens the door to the possibility of genetic screening for the LRRK2 gene mutation, which is believed to be the most common genetic cause of inherited Parkinson's disease identified to date.

Released: 7-Feb-2005 2:00 PM EST
Asthma Gene Clusters Identified
Cincinnati Children's Hospital Medical Center

Children who suffer from acute asthma attacks share a genetic profile that appears to be unique to these children, according to a new study. The discovery opens the door to the possibility of designing treatments specifically tailored to children who suffer from the severest forms of asthma.

21-Apr-2006 4:30 PM EDT
Study Links ADHD Cognitive and Behavioral Problems To Gene and Environment
Cincinnati Children's Hospital Medical Center

A new study indicates that cognitive and behavioral problems that underlie Attention Deficit Hyperactivity Disorder (ADHD) are due to a complex underplay of genes and the environment.

Released: 9-Oct-2006 2:35 PM EDT
Potential Target for Leukemia Treatment
Cincinnati Children's Hospital Medical Center

Cincinnati Children's Hospital Medical Center today announced the publication of pioneering research identifying the crucial role and novel mechanism of action of the protein RhoH GTPase in the development and activation of cells critical to the immune system. The findings, along with other studies, suggest that RhoH GTPase may provide a target for therapeutic intervention in some types of leukemia.

Released: 6-Jun-2007 12:00 PM EDT
New Criteria Help Detect Bone Deficiencies in Ill Children
Cincinnati Children's Hospital Medical Center

A study authored by a researcher at Cincinnati Children's Hospital Medical Center reports on work to develop standardized criteria to detect bone mass deficiencies in children with chronic diseases.

Released: 17-Jul-2007 1:00 PM EDT
Children Should Rely on Safety Equipment to Prevent Sports Injuries Brain Injury Fractures
Cincinnati Children's Hospital Medical Center

Many children return to school sports, such as soccer, football, cross-country and volleyball in late-July or early-August. Jon Divine, M.D., director of Sports Medicine at Cincinnati Children's Hospital Medical Center, says it's most important for children to be in shape even before showing up for the first day of practice or tryouts to reduce the risk of injury.

Released: 17-Jul-2007 1:00 PM EDT
Eating Nutritional Foods Can Help Children Be at Their Best Academically
Cincinnati Children's Hospital Medical Center

The start of the school year also means the return of school lunches, and the choice of brown-bagging or eating in the cafeteria. A nutritionist at Cincinnati Children's Hospital Medical Center says that it may seem contrary to perception, but a lunch from home may be the better choice, nutritionally.

Released: 17-Jul-2007 1:00 PM EDT
Emphasize the Positive When Talking to Children About Returning to School
Cincinnati Children's Hospital Medical Center

"Taking time to talk with and listen to children about the upcoming school year is one of the best ways parents can help them make the transition to school life," says David Smith, Ph.D., child psychologist at Cincinnati Children's Hospital Medical Center. Dr. Smith advises parents to begin talking about school a couple weeks before it starts, and to listen closely for their children's fears or concerns.

Released: 17-Jul-2007 1:00 PM EDT
Bus, Pedestrian and Home Safety
Cincinnati Children's Hospital Medical Center

Cincinnati Children's Hospital Medical Center has many pedestrian, bus riding and home safety tips to help parents prepare to send their children back to school.

Released: 26-Jul-2007 11:30 AM EDT
Gene Expression May Lead to Improved Treatment of Pediatric Septic Shock
Cincinnati Children's Hospital Medical Center

A consortium of researchers headed by Cincinnati Children's Hospital Medical Center has discovered a gene expression pattern that could lead to improved diagnosis and treatment of pediatric septic shock.

Released: 1-Oct-2007 4:00 AM EDT
Halloween and Food Allergy Safety
Cincinnati Children's Hospital Medical Center

Experts estimate that food allergy occurs in six to eight percent of children four years of age or under, and in four percent of adults. In recent years, it was reported that an estimated 29,000 people go to US emergency rooms each year as a result of allergic reactions to food. Parents whose children have food allergies need to be aware of how to protect their children from having allergic reactions when Trick-or-Treating.

Released: 10-Oct-2007 10:35 AM EDT
Severe Heart Defect Likely Caused by Genetic Factors
Cincinnati Children's Hospital Medical Center

Hypoplastic Left Heart Syndrome (HLHS), a severe cardiovascular malformation that is difficult to treat and often lethal, is caused primarily by genetic factors, according to a new study by researchers at Cincinnati Children's Hospital Medical Center.

Released: 16-Nov-2007 9:45 AM EST
Blood Clotting Protein Linked to Rheumatoid Arthritis
Cincinnati Children's Hospital Medical Center

Researchers at Cincinnati Children's suggest that therapies designed to interrupt the localized interaction of inflammatory cells and the blood clotting protein, fibrin, may help arthritis patients.

Released: 5-Aug-2008 3:50 PM EDT
Eating a Healthy Breakfast and a Nutritious Lunch Can Help a Child be His Or Her Best Academically
Cincinnati Children's Hospital Medical Center

Improving health and nutrition in undernourished children is correlated with less absenteeism, more grades completed and better performance on tests. Good nutrition also improves mental and behavioral performance. Eating well everyday is good insurance for parents that children arrive to school ready to learn.

Released: 6-Aug-2008 11:50 AM EDT
Parents Need to Talk to Children About Safety When Sending Them Back to School
Cincinnati Children's Hospital Medical Center

On average16 school-age pedestrians are killed by school transportation vehicles (school buses and non-school bus vehicles used as school buses) each year, and five are killed by other vehicles involved in school bus-related crashes. More school-age pedestrians are killed in the afternoon than in the morning. A Cincinnati Children's expert offers tips to parents for keeping their kids safe when they return to school.

Released: 6-Aug-2008 12:15 PM EDT
Parents Should Make Sure They Help Their Child Select a Good Backpack When Returning to School
Cincinnati Children's Hospital Medical Center

In May 2002, the U.S. Consumer Product Safety Commission reported backpack related injuries sent almost 6000 students each year to emergency rooms. The American Academy of Orthopedics stated that backpack injury is a significant problem for children.

Released: 6-Aug-2008 12:40 PM EDT
Talking to the Kids about Returning to School? Emphasize the Positive
Cincinnati Children's Hospital Medical Center

"Taking time to talk with and listen to children about the upcoming school year is one of the best ways parents can help them make the transition to school life," says David Smith, Ph.D., clinical child psychologist in the Division of Developmental and Behavioral Pediatrics of Cincinnati Children's Hospital Medical Center.

Released: 6-Aug-2008 12:40 PM EDT
Children Should Rely on Safety Equipment to Prevent School Sports Injuries
Cincinnati Children's Hospital Medical Center

Many children return to school sports, such as soccer, football, cross-country and volleyball in late-July or early-August. Jon Divine, M.D., director of Sports Medicine at Cincinnati Children's Hospital Medical Center, says it's most important for children to be in shape even before showing up for the first day of practice or tryouts to reduce the risk of injury.

Released: 2-Sep-2008 2:00 PM EDT
Mom, School’s Making Me Sick!
Cincinnati Children's Hospital Medical Center

With summer ending and school underway, parents are transitioning from hearing their children moan about not being able to swim everyday, to their child complaining about homework, their new teachers or being in a different class than their friends. Many parents also begin to hear more complaints of tummy aches and headaches as a result of returning back to school. The psychological term for school-induced illnesses a child may develop when he or she is trying to dodge school is School Avoidance, or School Refusal. Symptoms include nausea, fatigue, headaches and abdominal pain.

Released: 22-Oct-2008 12:50 PM EDT
Halloween and Food Allergy Safety
Cincinnati Children's Hospital Medical Center

While Halloween can be a fun holiday for children who Trick-or-Treat, the night can indeed be a scary experience for any of the three million youth who suffer from food allergy. Experts estimate that food allergy occurs in six to eight percent of children four years of age or under, and in four percent of adults. In recent years, it was reported that an estimated 29,000 people go to US emergency rooms each year as a result of allergic reactions to food.

Released: 22-Oct-2008 12:55 PM EDT
Halloween Safety Tips for Families: Precautions You Should Take to Keep Your Children Safe
Cincinnati Children's Hospital Medical Center

Parents should be extra vigilant for possible safety hazards so that children have a fun, healthy and safe Halloween.

Released: 2-Dec-2008 12:45 PM EST
Holiday Hazard Tips from The Drug and Poison Information Center
Cincinnati Children's Hospital Medical Center

The holiday season is usually a time of joy but it also brings the potential for poisonings, according to the Drug and Poison Information Center (DPIC), a service of Cincinnati Children's Hospital Medical Center. The following information includes safety hazards and precautionary ways to ensure that families have a safe holiday season.

Released: 2-Dec-2008 12:50 PM EST
Expert Offers Advice on How to Choose Age Appropriate and Safe Toys for Children During the Holidays
Cincinnati Children's Hospital Medical Center

With the excitement of the holidays, parents and relatives eagerly purchase the hottest toys and latest items for their children. But it's during the hustle and bustle of the season that many fail to buy age appropriate gifts for their children and they tend to disregard warnings on these toys and gifts when it comes to ensuring safety.

Released: 10-Dec-2008 7:30 AM EST
Parents Be Aware this Holiday Season - Magnets In Children’s Toys Pose Significant Health Risk
Cincinnati Children's Hospital Medical Center

A Cincinnati Children's Hospital Medical Center study shows that a growing number of adults know about the potential risk of swallowing magnets, but medical complications from magnets continue to be extensive worldwide and throughout childhood.

13-Jan-2009 10:10 AM EST
Engineered Virus Kills Neuroblastoma Cancer Stem Cells
Cincinnati Children's Hospital Medical Center

Researchers led by Cincinnati Children's Hospital Medical Center identified an apparent population of cancer stem cells for neuroblastoma, then used a reprogrammed herpes virus to block tumor formation in mice by targeting and killing the cells.

16-Feb-2009 11:15 AM EST
Gene Mutation Adds Risk in Child Kidney Transplants
Cincinnati Children's Hospital Medical Center

Screening for mutations in a gene that helps the body metabolize a kidney transplant anti-rejection drug may predict which children are at higher risk for toxic side effects, according to new research in Clinical Pharmacology and Therapeutics.

23-Feb-2009 1:00 PM EST
Gene Modifies Severity of Cystic Fibrosis Lung Disease
Cincinnati Children's Hospital Medical Center

Researchers have discovered a gene that modifies the severity of lung disease in people with the lethal genetic condition, cystic fibrosis, pointing to possible new targets for treatment, according to a new study in Nature.

19-Mar-2009 10:35 AM EDT
Protein That Reactivates Latent HSV Discovered
Cincinnati Children's Hospital Medical Center

Research in Public Library of Science (PLoS) Pathogens appears to solve a long standing medical mystery by identifying a viral protein, VP16, as the molecular key that prompts herpes simplex virus (HSV) to exit latency and cause recurrent disease.

Released: 21-Apr-2009 12:05 PM EDT
Hospital Care Varies Greatly for Children with Urinary Tract Infections
Cincinnati Children's Hospital Medical Center

More than 45,000 infants and children in the United States are hospitalized each year for urinary tract infections, but a new study reveals significant variability across hospitals in treatment and outcomes.

29-Apr-2009 10:25 AM EDT
Lack of Food Variety Puts Kids with Autism at Risk for Poor Nutrition
Cincinnati Children's Hospital Medical Center

The strong preference kids with autism have for certain foods places them at risk for nutritional deficiencies because their diets lack sufficient variety, according to research from Cincinnati Children's Hospital Medical Center at this year's Pediatric Academic Societies meeting in Baltimore.


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