10-Oct-1999 12:00 AM EDT
New Approach to Treating Cystic Fibrosis
Beth Israel Lahey Health

Boston researchers say they have discovered a reversible lipid imbalance that may be responsible for the common symptoms of cystic fibrosis. The discovery, in mice carrying the genetic defect that causes cystic fibrosis, could lead to a treatment.

3-Nov-1999 12:00 AM EST
Aging Stereotypes May Effect Gait of Older Persons
Beth Israel Lahey Health

Positive words picked up the walking pace of older persons, according to a Boston study that blames a pessimistic outlook on aging for the slower treads typical of many older people. Walking speed can predict future health and independence in older persons, according to research published in the November issue of the Journal of the American Geriatrics Society.

16-Nov-1999 12:00 AM EST
Illness Severity Predicts Death in Older Sick People
Beth Israel Lahey Health

Age plays only a small role in the risk of short-term death among seriously ill people, according to researchers at Beth Israel Deaconess Medical Center in Boston. People who were the sickest had the highest risk of death, according to the report in the Nov. 16 Annals of Internal Medicine.

24-Nov-1999 12:00 AM EST
New Pain Reliever for Rheumatoid Arthritis
Beth Israel Lahey Health

A new arthritis drug provides the same relief of pain and inflammation in people with rheumatoid arthritis as a typical nonsteroidal anti-inflammatory drug but with fewer ulcers and other gastrointestinal side effects, according to a study led by a researcher at Beth Israel Deaconess Medical Center in Boston.

Released: 6-Jan-2000 12:00 AM EST
Mechanism for Growing New Blood Vessels
Beth Israel Lahey Health

As published in the monthly journal Nature Medicine, cardiology researchers at Beth Israel Deaconess Medical Center have discovered a potentially more potent way to grow new blood vessels in the heart to bypass clogged arteries.

Released: 20-Jan-2000 12:00 AM EST
A Model Complementary/Integrative Care Center
Beth Israel Lahey Health

The Medtronic Foundation has awarded Beth Israel Deaconess Medical Center $900,000 to support the development of core infrastructure for a clinical facility that integrates conventional and complementary care services.

Released: 25-Feb-2000 12:00 AM EST
Town Meeting on Complementary and Alternative Medicine
Beth Israel Lahey Health

The National Center for Complementary and Alternative Medicine at NIH and Beth Israel Deaconess Medical Center is hosting a town meeting (3-15-00 in Boston) on complementary and alternative medicine.

3-Mar-2000 12:00 AM EST
Marijuana Use Can Trigger Heart Attack
Beth Israel Lahey Health

In the first hour after smoking marijuana, a person's risk of a heart attack can shoot up nearly five-fold, say researchers at Beth Israel Deaconess Medical Center.

Released: 18-Mar-2000 12:00 AM EST
Beth Israel Deaconess: News Tips in Science, Medicine
Beth Israel Lahey Health

1- Memory 101: training improves memory; 2- Recipes for a healthy menopause; 3- Research support grows at Beth Israel Deaconess; 4- Media calendar.

28-Apr-2000 12:00 AM EDT
Understanding Migraines and Effective Treatments
Beth Israel Lahey Health

The painfully sensitive skin that accompanies many migraines has revealed a new understanding of the debilitating headaches; the study, by Boston researchers, is the first human test of a migraine model that may explain why current medications are ineffective in many cases and suggests a new target for the next generation of migraine drugs (Annals of Neurology, 5-00).

Released: 28-Apr-2000 12:00 AM EDT
Hypnosis Reduces Surgical Pain and Time
Beth Israel Lahey Health

People who used self-hypnotic relaxation techniques during surgery needed less pain medication, left the operating room sooner, and had more stable vital signs during the operation, according to a Beth Israel Deaconess Medical Center study in the April 29 Lancet.

29-Jun-2000 12:00 AM EDT
William Cohn Receives Distinguished Inventor Award
Beth Israel Lahey Health

The Intellectual Property Owners Assoc. is honoring William Cohn, a Beth Israel Deaconess cardiothoracic surgeon, for inventing a device that makes it possible to perform coronary artery bypass surgery on a beating heart without using a heart-lung machine.

5-Jul-2000 12:00 AM EDT
Use, Misuse of Antibiotics to Prevent Heart Infections
Beth Israel Lahey Health

Testing guidelines aimed at preventing life-threatening heart infections, Boston researchers find underuse of antibiotics before dental work among people at moderate risk and overuse of antibiotics among low-risk patients, according to a study of 218 patients.

Released: 3-Aug-2000 12:00 AM EDT
Beth Israel Tipsheet: Science, Medicine and Health
Beth Israel Lahey Health

1- Web site gives patients access to their medical records; 2- Web resource aims to speed research on heartbeats, brain waves; 3- Vascular surgery on diabetics' legs proves long-term success; 4- Engineered skin-like tissue heals more diabetic foot ulcers faster.

Released: 19-Sep-2000 12:00 AM EDT
Persistent Smoking Reduces Full Benefits of Angioplasty
Beth Israel Lahey Health

People who never smoked or quit smoking after undergoing balloon angioplasty and other procedures to open obstructed heart arteries had greater improvements in health-related quality of life compared to people who continued to smoke, say researchers at Beth Israel Deaconess Medical Center (Journal of the American Heart Association, 9-19-00).

20-Oct-2000 12:00 AM EDT
AIDS Vaccine Harnesses Killer Immune Cells in Animals
Beth Israel Lahey Health

A team headed by researchers from Beth Israel Deaconess Medical Center in Boston has shown that AIDS vaccines designed to boost the immune response of "killer" T cells were successful in suppressing an unusually virulent strain of the AIDS virus and preventing clinical disease in monkeys. (Science, 10-20-00)

5-Dec-2000 12:00 AM EST
Technologies Improve Care for High-Risk Infants
Beth Israel Lahey Health

Incorporating Internet-based telemedicine technologies into the care of a very low birth weight infant results in greater family satisfaction with the care and may reduce the infant's length of hospitalization, per a Beth Israel Deaconess Medical Center study.

18-Jan-2001 12:00 AM EST
Right Side of Brain May be Key to Recognizing Yourself
Beth Israel Lahey Health

The right side of the brain helps people recognize themselves in a picture, say researchers at Beth Israel Deaconess Medical Center in Boston. (Nature, 1-18-01)

8-Feb-2001 12:00 AM EST
Fat Cell Defect May Trigger Insulin Resistance in Muscle and Liver
Beth Israel Lahey Health

Fat cells that can't take up blood sugar normally appear to trigger the same problem in muscle and a related problem in liver. The findings in mice may begin to explain why obesity is a risk factor for type 2 diabetes in humans and may shed light on the earliest defect in type 2 diabetes -- insulin resistance. (Nature, 2-8-01)

18-Apr-2001 12:00 AM EDT
Moderate Drinkers' Mortality Risk after Heart Attack
Beth Israel Lahey Health

People with heart disease who consume moderate levels of alcohol may have a lower risk of mortality after suffering a heart attack than those who abstained from alcohol, according to study led by researchers at Beth Israel Deaconess Medical Center.

Released: 25-Apr-2001 12:00 AM EDT
Medicare Lifestyle Modification Program Demonstration
Beth Israel Lahey Health

The Health Care Financing Administration has invited the Mind/Body Medical Institute's Cardiac Wellness Program to participate in multi-year Medicare Lifestyle Modification Program Demonstration. The Cardiac Wellness Program will be offered to up to 1,800 Medicare beneficiaries with heart disease.

7-Jun-2001 12:00 AM EDT
Nonviral Gene Therapy for Hemophilia Safe and Beneficial
Beth Israel Lahey Health

A phase I study at Beth Israel Deaconess has demonstrated that a factor VIII gene therapy-based treatment for severe hemophilia A is safe, well-tolerated and may be effective in reducing the occurrence of spontaneous bleeding.

12-Jun-2001 12:00 AM EDT
Air Pollution May Trigger Heart Attack in At-Risk Patients
Beth Israel Lahey Health

Brief exposure to elevated levels of fine particulate air pollution - as little as two hours - may temporarily increase the risk of heart attack particularly among people already at risk for heart disease, according to a study led by researchers at Beth Israel Deaconess Medical Center.

12-Jun-2001 12:00 AM EDT
Marijuana Use May Pose Health Threat to Baby Boomers
Beth Israel Lahey Health

People who smoke marijuana may increase their risk of a heart attack, Beth Israel Deaconess researchers have found. A person's chance of having a heart attack, particularly those at risk for heart disease, increased nearly 5X during the hour after smoking.

15-Jun-2001 12:00 AM EDT
Potential Mechanism Linking Obesity to Type 2 Diabetes
Beth Israel Lahey Health

Problems with a protein buried deep within pancreatic beta cells may explain how obesity evolves into type 2 diabetes, according to new evidence from Beth Israel Deaconess researchers and others. The experiments in mice suggest a new approach to therapies in humans.

Released: 2-Aug-2001 12:00 AM EDT
Diabetes Increases Women's Risk for Dying After a Heart Attack
Beth Israel Lahey Health

Women who have diabetes have a substantially greater risk of dying a few years after suffering a heart attack than do non-diabetic women, according to a study led by Beth Israel Deaconess Medical Center researchers.

28-Aug-2001 12:00 AM EDT
Chromosome Location of Genes Associated with Long Life Identified
Beth Israel Lahey Health

Researchers at Beth Israel Deaconess Medical Center, Children's Hospital Boston and other institutions have pinpointed a region on human Chromosome 4 that is likely to contain a gene or genes associated with extraordinary life expectancy.

4-Sep-2001 12:00 AM EDT
CAM Therapies and Conventional Care Satisfaction
Beth Israel Lahey Health

Adults who use complementary and alternative medical therapies (CAM) in addition to conventional medicine appear to value both - and tend to be more concerned about their physician's inability to understand or incorporate CAM therapy than they are in their physician's disapproval, researchers at Berth Israel Deaconess Medical Center and Harvard Medical School have found.

7-Dec-2001 12:00 AM EST
Single Enzyme May Be Linked to Obesity
Beth Israel Lahey Health

The increased activity of a single enzyme in fat cells may be a common cause of obesity and obesity-linked diseases, including diabetes, according to an animal study conducted by researchers at Beth Israel Deaconess Medical Center and the University of Edinburgh. The findings could eventually pave the way for future drug development to curb visceral obesity - the "beer belly" fat concentrated in the abdomen.

27-Dec-2001 12:00 AM EST
Coronary Magnetic Resonance Angiography as Equal to X-ray Angiography
Beth Israel Lahey Health

Three-dimensional coronary magnetic resonance angiography is highly accurate in diagnosing coronary artery disease, while eliminating the risks and discomfort of the more traditional X-ray angiography procedure, according to a multi-center clinical trial headed by investigators at Beth Israel Deaconess Medical Center and conducted at the BIDMC and six other sites around the world.

Released: 28-Dec-2001 12:00 AM EST
Animal Study Find Embryonic Stem Cells Can Repair Heart Muscle
Beth Israel Lahey Health

Transplantation of embryonic stem cells can help repair injured heart muscle and improve cardiac function following heart attacks and the development of congestive heart failure (CHF), according to the results of an animal study conducted at Beth Israel Deaconess Medical Center.

4-Jan-2002 12:00 AM EST
Researchers Explain How Protein Inhibits Angiogenesis
Beth Israel Lahey Health

A new discovery led by a team of researchers at Beth Israel Deaconess Medical Center offers one of the first explanations for how angiogenesis - the growth of small blood vessels - is inhibited in the body. The study focuses on a protein called tumstatin, and could prove key to understanding how to stop the overgrowth of blood vessels that occur in cancerous tumors when the angiogenesis process goes awry.

17-Jan-2002 12:00 AM EST
Researchers Identify Link Between Obesity And Type 2 Diabetes
Beth Israel Lahey Health

Researchers at Beth Israel Deaconess Medical Center have identified a mechanism that helps explain how the hormone leptin acts to metabolize fatty acids in muscle, establishing for the first time a novel molecular link between obesity and diabetes, and creating the possibility of a new target for the development of drugs to help manage both conditions.

Released: 23-Jan-2002 12:00 AM EST
Can Weight Loss Decrease Heart Disease in Type 2 Diabetes?
Beth Israel Lahey Health

More than 40 men and women from the Boston area - ranging from nurses to accountants to retirees - have already put their New Year's resolutions to lose weight and exercise more to the ultimate test by enrolling in the first long-term study to look at the effects of weight loss in people with type 2 diabetes in a nationwide study conducted locally at Massachusetts General Hospital, Joslin Diabetes Center and Beth Israel-Deaconess Medical Center.

Released: 12-Feb-2002 12:00 AM EST
Physicians Warn of Nuclear Terrorist Threat
Beth Israel Lahey Health

In the aftermath of September 11, the threat of nuclear terrorism is among the most real -- and most dire -- of our country's current public health concerns, according to a report in the the British Medical Journal (BMJ), which estimates that a Hiroshima-scale nuclear explosion on a ship in port in New York City would result in more than 250,000 deaths.

22-Mar-2002 12:00 AM EST
Researchers Identify Immune Response to Tuberculosis Infection
Beth Israel Lahey Health

A new discovery by a scientific team headed by researchers at Beth Israel Deaconess Medical Center has found that a group of white blood cells demonstrates previously unrecognized "memory" characteristics that enable them to launch a sustained immune response against tuberculosis bacteria.

15-Apr-2002 12:00 AM EDT
Outstanding Surgical Outcomes for Diabetes Patients
Beth Israel Lahey Health

Contrary to the long-held belief that surgery poses a significant danger to patients with diabetes mellitus, a 10-year study of more than 6,500 patients from Beth Israel Deaconess Medical Center has shown a mortality rate of only 1 percent among diabetes patients undergoing major vascular operations.

Released: 19-Apr-2002 12:00 AM EDT
Researchers Identify Protein That Overcomes Leptin Resistance
Beth Israel Lahey Health

The identification of a protein that enables the body to overcome resistance to the hormone leptin could help scientists move one step closer to creating a drug therapy to help prevent and treat obesity.

7-May-2002 12:00 AM EDT
Heart Attack Patients May Benefit From Drinking Tea
Beth Israel Lahey Health

Drinking tea on a regular basis may help protect patients with existing cardiovascular disease, according to a study which finds that tea consumption is associated with an increased rate of survival following a heart attack.

25-Jun-2002 12:00 AM EDT
Researchers Identify Protein Linked To Tumor Invasion
Beth Israel Lahey Health

A protein known for its role in helping to provide the body's immune system with a line of defense against infection has unexpectedly been discovered in cancer cells that were removed from aggressive carcinomas of the breast and colon.

25-Jun-2002 12:00 AM EDT
Simple Reminder Can Help Patients Avoid Dangerous Infection
Beth Israel Lahey Health

A study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) finds that a simple reminder to their doctors can help patients with valvular heart disease to remember to take antibiotics before having their teeth cleaned or undergoing other procedures that may be associated with subsequent heart infections.

Released: 11-Jul-2002 12:00 AM EDT
Diabetes Treatment Linked to Increased Blood Pressure in Animal Study
Beth Israel Lahey Health

A report has found that a group of drugs currently under development for the treatment of Type II diabetes caused both increased heart rate and elevated blood pressure in animal studies.

19-Jul-2002 12:00 AM EDT
Study Identifies Protein In Human Brain Development
Beth Israel Lahey Health

Researchers have identified a protein that may help to explain why the brain's cerebral cortex is disproportionately larger in humans than in other species, a finding which adds an important piece to the developing "blueprint" of the part of the brain responsible for the intellectual abilities that make humans unique.

26-Jul-2002 12:00 AM EDT
Brain Pathway to Explain How Fenfluramine Causes Weight Loss
Beth Israel Lahey Health

Scientists have identified the molecular pathway in the brain that helps explain how the once-popular diet drug d-Fenfluramine (d-FEN) works to promote weight loss.

2-Aug-2002 12:00 AM EDT
Pathway That Helps Keep Weight in Check
Beth Israel Lahey Health

A study led by researchers at Beth Israel Deaconess Medical Center offers a new explanation for how the brain makes adjustments to the body's metabolic rate to prevent extra calories from turning into extra pounds.

Released: 16-Aug-2002 12:00 AM EDT
Disaster Management Training for United Nations
Beth Israel Lahey Health

The director of Beth Israel Deaconess Medical Center's division of international disaster and emergency medicine was sleeping after a night in the emergency department when the call came on Sept. 11, 2001. A second airplane had struck the World Trade Center and his Disaster Medical Assistance Team was being activated.

11-Sep-2002 12:00 AM EDT
Greater Incidence of Obesity among Adults with Disabling Conditions
Beth Israel Lahey Health

As significant a problem as obesity is among the general population, it's an even greater problem for adults with disabling conditions, according to a study which also found that, in general, patients with disabilities were as likely to try to lose weight as were overweight adults without disabilities.

Released: 18-Oct-2002 12:00 AM EDT
Trauma Surgeon Seeks Change in Law Discouraging Counseling of Problem Drinkers
Beth Israel Lahey Health

Larry Gentilello, MD, believes we have an excellent system for trauma care in the US. Yet, injuries -- many of them alcohol-related -- are the leading cause of death for Americans under 44 years of age. "Now, it's time to move forward to prevent injuries," he says. "And to change archaic laws that discourage effective alcohol counseling that has been demonstrated to dramatically reduce injuries and readmissions to trauma centers."

9-Jan-2003 12:00 AM EST
Frequent Consumption of Alcohol Linked to Lower Risk of Heart Attack in Men
Beth Israel Lahey Health

Daily or near-daily servings of beer, wine or spirits may help protect men from heart attacks, according to the results of a large, long-term study by researchers at Beth Israel Deaconess Medical Center and the Harvard School of Public Health.

Released: 24-Jan-2003 12:00 AM EST
Animal Study Demonstrates Carbon Monoxide May Help Heart Patients
Beth Israel Lahey Health

Carbon monoxide, the toxic gas generally associated with auto exhaust or faulty heating systems, may have a protective role in preventing the development of dangerous arteriosclerotic lesions that can clog blood vessels following balloon angioplasty or aortic transplantation.


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