The effects of sustained drug abuse can manifest in many ways. Loss of memory and reduced cognitive functions are some of the effects that can persist for years. Scientists at UC San Diego have now identified a mechanism in the brain that generates drug-induced cognitive impairments.
Researchers at The University of Texas at El Paso will undertake a new study that could lead to improved nicotine cessation treatments for women. The work is supported by a new $2.5 million grant from the National Institute on Drug Abuse, part of the National Institutes of Health.
Chronic pain can be debilitating and can limit the quality of life for the millions who suffer from it. Unfortunately, treatments to manage chronic pain are often ineffective because the functional changes that accompany a disease are not fully understood. Many patients develop chronic pain after surgery, but unfortunately, it is not yet possible to predict which patients are at risk.
People with chronic pain who take opioids have trouble finding multimodal pain care; insurance and provider education changes are needed, experts say.
Scientists have long used community advisory boards to engage communities and provide feedback on studies, but this model has limitations. Now, Wistar Institute researchers are sharing how a more inclusive model for community engagement can lead to deeper insights and greater community participation in HIV research.
New research shows that drinkers with alcohol use disorder display the same level of fine motor and cognitive impairment as light drinkers when consuming their usual excessive amount.
Men were significantly more vulnerable than women to overdose deaths involving opioid and stimulant drugs in 2020-2021, according to a new study analyzing data from across the United States.
Despite getting “the munchies”, people who frequently use cannabis are leaner and less prone to diabetes than those who don’t. University of California, Irvine researchers have now uncovered a possible explanation for this paradox – and it’s not good news.
Leveraging the HEALing Communities Study infrastructure, researchers are testing whether there is an association between fentanyl test strip use and overdose risk reduction behaviors among people who use drugs over a 28-day observation period. The Stay Safe Study will be in Kentucky, Ohio and New York.
A new study of more than 50,000 US adolescents across the country indicates that vaping nicotine is strongly linked with an increased likelihood of high levels use of binge drinking and cannabis usage.
A study, led by University of Oregon neuroscientist Shawn Lockery, points to worms as a useful tool for understanding more about the many roles that cannabinoids naturally play in the body. And it could help researchers develop better drugs that target this system.
Researchers have identified a strong association between prevalence of prescription stimulant therapy for attention-deficit/hyperactivity disorder (ADHD) and rates of prescription stimulant misuse (taken in a way other than as directed by a clinician) by students in middle and high schools.
U.S. middle and high schools with the most students taking prescription stimulants to treat ADHD also had, overall, the highest percentage of students who misused prescription stimulants within the past year.
An online “e-health” program helped more people with chronic pain reduce their opioid medications and pain intensity than a control group that had only regular treatment in a recent clinical study.
New research led by Washington University School of Medicine in St. Louis identifies a common genetic signature that may increase a person's risk of developing substance use disorders. The work eventually could lead to universal therapies to treat multiple substance use disorders and potentially help people diagnosed with more than one.
In a new study, University of California, Irvine researchers found that exposure to the compound tetrahydrocannabinol (THC), a component of cannabis, at a young age could lead to depleted ovarian follicles and matured eggs in adulthood by nearly 50 percent.
A new study from Boston University Chobanian & Avedisian School of Medicine has found that a brief stigma intervention that specifically targets people with HIV who inject drugs was effective in increasing engagement in substance use care as well as improving their ART adherence.
Analysis reveals similar changes in the brain’s functioning in both humans and mouse models
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