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Dermatology

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Medicine

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Herpes, Epstein Barr Virus, Cryo Electron Microscopy, Kshv, AIDS, Kaposi's Sarcoma

UCLA Study Describes Structure of Tumor Herpes Virus Associated with Kaposi's Sarcoma

UCLA team shows in the laboratory that an inhibitor can be developed to break down the herpes virus.

Medicine

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Melanoma, MD Anderson Cancer Center, clinical trial, Surgery, Targeted Therapy, BRAF, MEK

Presurgical Targeted Therapy Delays Relapse of High-Risk Stage 3 Melanoma

A pair of targeted therapies given before and after surgery for melanoma produced at least a six-fold increase in time to progression compared to standard-of-care surgery for patients with stage 3 disease, researchers at The University of Texas MD Anderson Cancer Center report in Lancet Oncology. Patients who had no sign of disease at surgery after combination treatment did not progress to metastasis.

Medicine

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Atopic Dermatitis, Light, TNF super family, Fibrosis

LJI Researchers Discover Key Driver of Atopic Dermatitis

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La Jolla Institute scientists demonstrate that LIGHT, a member of the tumor necrosis factor (TNF) super family, directly controls the hyperproliferation of keratinocytes as well as the expression of periostin, a protein that contributes to the clinical features of atopic dermatitis as well as other inflammatory skin diseases such as scleroderma.

Medicine

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Melanoma, Cancer, Drug Resistance, Dendritic Cells

Researchers Identify New Way to Unmask Melanoma Cells to the Immune System

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A research team at the Duke Cancer Institute has found a new way to keep the immune system engaged, and is planning to test the approach in a phase 1 clinical trial.

Medicine

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American Academy Of Dermatology, Journal of the American Academy of Dermatology, JAAD, Dermatology, Dermatologists, Dermatologist

Journal of the American Academy of Dermatology Names New Editor

Board-certified dermatologist Dirk M. Elston, MD, FAAD, the current deputy editor of the Journal of the American Academy of Dermatology will step into his new role in July 2018, succeeding board-certified dermatologist Bruce H. Thiers, MD, FAAD, who has served as editor for the past 10 years.

Medicine

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Melanoma, GPER, Pregnancy, Estrogen, Immunotherapy

Penn Researchers Identify New Treatment Target for Melanoma

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Researchers in the Perelman School of Medicine at the University of Pennsylvania have identified a new therapeutic target for the treatment of melanoma. For decades, research has associated female sex and a history of previous pregnancy with better outcomes after a melanoma diagnosis. Now, a research team from Perelman School of Medicine at the University of Pennsylvania says it may have determined the reason for the melanoma-protective effect.

Medicine

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Melanoma, Immunotherapy, demoplastic melanoma, PD-1, PD-L1, anti PD-1 PDL-1 therapy

Rare Melanoma Type Highly Responsive to Immunotherapy

Desmoplastic melanoma is a rare subtype of melanoma that is commonly found on sun-exposed areas, such as the head and neck, and usually seen in older patients. Treatment is difficult because these tumors are often resistant to chemotherapy and lack actionable mutations commonly found in other types of melanoma that are targeted by specific drugs. However, Moffitt Cancer Center researchers report in the Jan. 10 issue of Nature that patients with desmoplastic melanoma are more responsive to immune-activating anti-PD-1/PD-L1 therapies than previously assumed.

Medicine

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Immunotherapy Highly Effective in Treatment of Rare Skin Cancer, Study Finds

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In a UCLA-led study, more than two-thirds of people with a rare type of melanoma responded positively to treatment with anti-PD-1 immunotherapies.

Medicine

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American Academy Of Dermatology, Clinical Guidelines, Nonmelanoma Skin Cancer, Basal Cell Carcinoma, Squamous Cell Carcinoma, Skin Cancer, Dermatology, Dermatologists, Dermatologist

American Academy of Dermatology Issues New Guidelines for Treatment of Nonmelanoma Skin Cancer

The American Academy of Dermatology has released new guidelines of care for the management of basal cell carcinoma and cutaneous squamous cell carcinoma. These evidence-based guidelines cover best practices for the management of nonmelanoma skin cancer.

Medicine

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water borne illness

Illnesses Caused by Recreation on the Water Costs $2.9 Billion Annually in the US

Swimming, paddling, boating and fishing account for more than 90 million cases of gastrointestinal, respiratory, ear, eye and skin-related illnesses per year in the U.S. with an estimated annual cost of $2.9 billion, according to a new report by University of Illinois at Chicago researchers.This is the first time the cost associated with waterborne illnesses contracted during recreational activities in the U.







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