Amid growing national interest in genealogy and family history, scholars from around the world will explore past and present meanings of family and kinship in a year-long seminar led by Tufts University and supported by the Mellon Foundation through its Sawyer Seminar program.
A new option – a combination of a standard drug and the novel agent venetoclax – has been granted accelerated approval by the Food and Drug Administration for certain AML patients after a large, multicenter phase 1 clinical trial showed the combination had “promising efficacy” and was well tolerated in older AML patients.
Children who enter elementary school younger than their peers are more likely to be diagnosed with ADHD. Children born in August in states with a Sept. 1 cutoff birth date for school enrollment have a 30 percent higher risk for ADHD diagnosis than peers born in September, which may reflect over-diagnosis.
BIDMC's Alexa Kimball, MD, shares important factors that influence how our skin looks and behaves.
Diabetes can cause problems with your feet. BIDMC's John Giurini, DPM, Chief of Podiatric Surgery, discusses these complications and how experts at BIDMC can help.
Allen Taylor, a senior scientist and director of the Laboratory for Nutrition and Vision Research at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, named a Fellow of the American Association for the Advancement of Science (AAAS).
Physicians at Massachusetts Eye and Ear have, for the first time, induced a sense of smell in humans by using electrodes in the nose to stimulate nerves in the olfactory bulb, a structure in the brain where smell information from the nose is processed and sent to deeper regions of brain. Reporting online today in International Forum of Allergy & Rhinology, the research team describes their results, which provide a proof of concept for efforts to develop implant technology to return the sense of smell to those who have lost it.
• $1 million in initial funding to evaluate DNA repair inhibitors in pancreatic cancer • Aim to accelerate pancreatic cancer research and improve patient outcomes for pancreatic cancer
Dana-Farber and Deerfield Management are collaborating to create the Center for Protein Degradation is to interrogate and advance a large portfolio of advanced targeted protein degrader targets while creating a next-generation protein degrader platform
A research team from Massachusetts Eye and Ear describes a newly discovered mechanism in a report published in the Journal of Allergy and Clinical Immunology (JACI). The findings shed new light on our immune systems — and also pave the way for drug delivery techniques to be developed that harness this natural transportation process from one group of cells to another.
A new book, Random Families: Genetic Strangers, Sperm Donor Siblings, and the Creation of New Kin, offers timely insights into an unprecedented phenomenon: how the discovery of half-siblings sharing donor DNA who are born into different families has created enormous networks of genetic kin.
Babson College, the No. 1 ranked college and global leader in entrepreneurship, is pleased to announce that FedEx Corp. has agreed to contribute an additional $500,000 to support the school’s Miami Women Innovating Now (WIN) Lab® to assist and encourage emerging women CEOs looking to create economic and social impact.
The first high-quality ancient DNA data from Central and South America reveals two previously unknown genetic exchanges between North and South America, one representing a continent-wide population turnover Findings link the oldestCentral and South American samples with the Clovis culture, the first widespread archaeological culture of North America; however, this lineage disappeared within the last 9,000 years Analyses show shared ancestry between ancient Californians from the Channel Islands and groups that became widespread in the southern Peruvian Andes by at least 4,200 years ago
The $200-million commitment will fund: o Fundamental curiosity-driven research and a therapeutics initiative to catalyze the development of new treatments o Integrated data science and artificial intelligence capabilities and applications o Cross-disciplinary research across the Harvard life sciences ecosystem o LifeLab Longwood, an incubator for early-stage, high-potential biotech start-ups In honor of the gift—the largest in Harvard Medical School history—the School will name a research institute for the donor to recognize the pioneering work of its basic science and social science departments.
Faculty from BIDMC's CardioVascular Institute and colleagues will be presenting new advances and research at the 2018 American Heart Association (AHA) Scientific Sessions.
The Association for Computing Machinery (ACM) has named Lynn Andrea Stein a 2018 Distinguished Member. Stein was recognized for educational innovations, including her work as one of Olin’s founding faculty members and her leadership of what is now Olin’s Collaboratory. Stein’s contributions are grounded in her scholarship on the philosophical foundations of computing and its applications.
Young people turned out at an estimated rate of 31 percent, a substantial increase over 2014 and a high-water mark for the last quarter century, according to an exclusive youth turnout analysis released by researchers from the Center for Information and Research on Civic Learning & Engagement (CIRCLE)—the preeminent, non-partisan research center on youth engagement at Tufts University’s Jonathan M. Tisch College of Civic Life.
Babson College, the #1 college and world leader in entrepreneurship, will celebrate its tradition of innovation by inducting Founder & CEO, SPANX, Inc. Sara Blakely, Founder Jesse Itzler and the late former Chairman and CEO, PepsiCo Inc., former Executive Chairman, DreamWorks, and former Trustee, Roger Enrico ’65, H’86 into Babson’s Academy of Distinguished Entrepreneurs during ceremonies on Babson’s Wellesley campus, Thursday, November 15, 2018.
Kathryn Weatherford, RD, LDN, CNSC, a registered dietitian at BIDMC, shares five food recommendations to help strengthen bones and joints.
Researchers led by Tufts University biologists and engineers have found that delivering progesterone to an amputation injury site can induce the regeneration of limbs in otherwise non-regenerative adult frogs—a discovery that furthers understanding of regeneration and could help advance treatment of amputation injuries. The researchers created a wearable bioreactor attached to the wound site to deliver the progesterone locally for a 24-hour period and observed that it had a lasting beneficial effect on tissue regrowth, allowing the frogs to partially regenerate their hind-limbs. A mere 24 hour of exposure led to 9 months of changes in gene expression, innervation, and patterned growth. The finding, published today in Cell Reports, suggests the drug-device combination could be a new model for systematically testing and deploying therapeutic cocktails that could induce regeneration in non-regenerative species.
Scientists have discovered a previously unknown molecular vulnerability in two rare, aggressive, and hard-to-treat types of cancer, and say it may be possible to attack this weakness with targeted drugs.
Scientists have discovered a previously unknown molecular vulnerability in two rare, aggressive, and hard-to-treat types of cancer, and say it may be possible to attack this weakness with targeted drugs.
Babson College has launched the Babson Academy, created to advance global entrepreneurial learning at universities around the world, provide faculty, administrators, and students of other educational institutions access to Babson’s thriving entrepreneurial ecosystem, and hoping to inspire change in the way universities and colleges think about, teach, and learn entrepreneurship.
A monthly roundup of research briefs showcasing recent scientific advances led by Beth Israel Deaconess Medical Center faculty.
In the largest analysis to date, researchers and clinicians at Beth Israel Deaconess Medical Center (BIDMC) have compared the efficacy and safety of non-surgical treatment options for tennis elbow – also called enthesopathy of the extensor carpi radialis brevis (eECRB).
A new study led by researchers at Massachusetts Eye and Ear found that good performance on a piloting task was associated with lower vestibular thresholds, which represent stronger ability to sense and perceive information about motion, balance and spatial orientation. Published online today in the Journal of Neurophysiology, the findings suggest that astronauts or pilots with higher vestibular thresholds are more likely to become disoriented during flight, especially in situations when gravity is less than that on Earth – such as on the Moon.
Three Harvard Medical School scientists have received the prestigious Allen Distinguished Investigator awards for their work in the fields of neuroimmunology, developmental biology and cancer.
In a study published online today by the journal Immunity, scientists at Dana-Farber Cancer Institute, Harvard Medical School, Vanderbilt University and colleagues at other institutions show how machinery within immune system T cells responds to outside signals and activates the cells to attack cancerous, infected, or otherwise diseased cells.
OpenNotes announced today that more than 30 million Americans now have access to notes written by their clinicians in fully transparent medical records.
Babson College, the #1 college and global leader for entrepreneurship, will offer a new program, Women Leaders Activating Change: Creating Value for You and Your Organization, at Babson Miami February 25-28 with an optional online session.
Study suggests close observation is a reasonable management strategy for moderately dysplastic moles, but certain patients require continued screening for risk for melanoma
Christen Deveney, assistant professor of psychology at Wellesley College, seeks clues to the factors that contribute to childhood irritability, a common but often misunderstood possible symptom of mental health issues.
Research in mice adds to evidence that dips in the activity of serotonin neurons may increase SIDS risk. The study reveals the activity of serotonin-producing neurons in the infant mouse brain contributes to a fail-safe switch that allows recovery from interrupted breathing. If replicated in human studies, findings could pave the way to screening for SIDS risk, new therapies.
Jihye Jang, a PhD Candidate at the Cardiac Magnetic Resonance Center at Beth Israel Deaconess Medical Center, and colleagues assessed AR’s potential to help cardiologists visualize myocardial scarring in the heart as they perform ventricular tachycardia ablation or other electrophysiological interventions.
The inaugural $100,000 Jean Mayer Prize for Excellence in Nutrition Science & Policy was awarded by Tufts to former Sen. Tom Harkin; former USDA Secretary Tom Vilsack; Center for Science in the Public Interest; and Mission: Readiness for their work championing better nutrition for America’s youth.
Recent studies have linked development of type 2 diabetes and impaired metabolic health individuals to their parents’ poor diet, and there is increasing evidence that fathers play an important role in obesity and metabolic programming of their offspring.In a new study published today in the journal Diabetes, researchers at Joslin Diabetes Center have shown that paternal exercise has a significant impact on the metabolic health of their offspring well into adulthood.
A team of Tufts University-led researchers has developed three-dimensional (3D) human tissue culture models for the central nervous system that mimic structural and functional features of the brain and demonstrate neural activity sustained over a period of many months.
In a review published in the journal Trends in Cognitive Science, Alvaro Pascual-Leone, MD, PhD, and colleagues describe how non-invasive brain stimulation – a technique he and others have pioneered to unlock the secrets of the brain – could shed light on the neurobiology underlying implicit bias.
Janey L. Wiggs, MD, PhD, the Paul A. Chandler Professor of Ophthalmology and Associate Director of the Ocular Genomics Institute at Harvard Medical School, and the Associate Chief for Clinical Research in Ophthalmology and Interim Glaucoma Service Director at Massachusetts Eye and Ear, has been elected to the prestigious National Academy of Medicine (NAM).
BOSTON (October 15, 2018) – Harnessing the power of digital health technology --- smart phone apps, telemedicine and mobile health (m-health) --- can provide powerful tools to help people with diabetes self-management, ultimately improving A1c levels, reducing complications and lowering healthcare costs, suggests a recent systematic review of studies first published online September 27 in the journal Cell Metabolism.
RNA methylation might prove important in regulating many aspects of beta cell behavior, such as how the cells divide or how effectively they are stimulated by blood glucose to produce insulin
Two studies into deadly cancers in dogs are now underway, offered through the newly formed Clinical Trials Office at Cummings Veterinary Medical Center at Tufts University. Dogs with spontaneous osteosarcoma, as well as dogs with mast cell tumors and solid tumors, may be eligible for enrollment.
BOSTON – (October 10, 2018) – Type 2 diabetes is driven by many metabolic pathways, with some pathways driven by amino acids, the molecular building blocks for proteins. Scientists at Joslin Diabetes Center now have shown that one amino acid, alanine, may produce a short-term lowering of glucose levels by altering energy metabolism in the cell.
A new study from Tufts researchers finds that two inflammatory proteins in the colon increase incrementally with weight. In individuals with obesity, this was accompanied by activation of precancerous cellular pathways.
Young voters are engaged in the 2018 midterm elections and plan to vote in higher numbers, according to new findings from an exclusive pre-election poll of young people, ages 18-24, from the Center for Information and Research on Civic Learning & Engagement (CIRCLE) at Tufts University's Tisch College.
Two decades ago, Clifford B. Saper, MD/PhD, Chairman of the Department of Neurology at Beth Israel Deaconess Medical Center, and colleagues discovered a set of nerve cells they thought might be the switch that turns the brain off, allowing it to sleep. In a new study, Saper and colleagues demonstrate in mice that that these cells – located in a region of the hypothalamus called the ventrolateral preoptic nucleus – are in fact essential to normal sleep.
In an ambitious effort to crack the code of several aggressive childhood cancers that lack definitive treatments, the federal Beau Biden Cancer Moonshot program has awarded grants of $2.5 million each over five years to two research teams led by scientists from Dana-Farber/Boston Children’s Cancer and Blood Disorders Center. Only three grants in total were awarded for this initiative.
In research that extends knowledge about the physiology of regeneration and wound repair, Tufts University biologists have discovered that amputation of one limb is immediately reflected in the bioelectric properties of the contralateral, or opposing, un-damaged limb of developing frogs.
A new Food-PRICE study from researchers at Tufts and Harvard estimates that up to one million cardiovascular and diabetes events and $42 billion could be saved in healthcare costs using incentives and/or disincentives to improve food choices among participants in SNAP.
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