Feature Channels: Digestive Disorders

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9-Jun-2023 3:05 PM EDT
Inflammatory Bowel Disease Linked to Increased Risk of Stroke
American Academy of Neurology (AAN)

People with inflammatory bowel disease (IBD) are more likely to have a stroke than people without the disease, according to a study published in the June 14, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study does not prove that IBD causes stroke; it only shows an association.

12-Jun-2023 6:35 PM EDT
Altered gut bacteria may be early sign of Alzheimer’s disease
Washington University in St. Louis

Alzheimer’s disease causes changes to the brain that begin two decades or more before symptoms appear. A study by researchers at Washington University School of Medicine in St. Louis reveals that the bacteria that live in the gut also change before Alzheimer’s symptoms arise, a discovery that could lead to diagnostics or treatments for Alzheimer’s disease that target the gut microbiome.

Newswise: Targeted Chemotherapy Helps Cure Some Inoperable Tumors
Released: 14-Jun-2023 12:25 PM EDT
Targeted Chemotherapy Helps Cure Some Inoperable Tumors
Cedars-Sinai

Physicians at Cedars-Sinai Cancer are using a unique chemotherapy delivery system that offers hope to colorectal cancer patients whose disease has spread and who now have inoperable liver tumors. Cedars-Sinai is one of the few centers in the area to offer the therapy, called hepatic artery infusion (HAI) pump chemotherapy.

Newswise: A surgical procedure trial compares efficacy of two reliable procedures to repair a hiatal hernia and put an end to heartburn and GERD symptoms
Released: 13-Jun-2023 3:30 PM EDT
A surgical procedure trial compares efficacy of two reliable procedures to repair a hiatal hernia and put an end to heartburn and GERD symptoms
University of Texas Health Science Center at Houston

For years, Mike Culp, 30, followed a highly restrictive diet and took medication to help manage his painful acid reflux symptoms that plagued his life and sleep. At age 18, he went to a specialist, who diagnosed him with gastroesophageal reflux disease (GERD). He was prescribed a proton-pump inhibitor (PPI), a medication that shuts off the acid-pumping cells in the stomach. His symptoms were temporarily managed, but he could not get rid of the burning, acidic-induced discomfort for long.

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Released: 12-Jun-2023 7:00 AM EDT
Por que o tratamento precoce do câncer de esôfago é importante
Mayo Clinic

O câncer esofágico, que ocorre no esôfago (o longo tubo que liga a garganta ao estômago) está aumentando em todo o mundo, em parte por que há mais pessoas apresentando dois dos principais fatores de risco.

Released: 12-Jun-2023 7:00 AM EDT
الأسباب وراء ضرورة علاج السرطان المريئي مبكرًا
Mayo Clinic

إن حالات السرطان المريئي، وهو سرطان يصيب المريء — الأنبوب الطويل المجوف الممتد من الحلق إلى المعدة — آخذة في الازدياد في جميع أنحاء العالم، ويرجع ذلك جزئيًا إلى زيادة إصابة الأشخاص بالعاملين الرئيسيين المسببين للمرض.

Released: 9-Jun-2023 1:35 PM EDT
Shed those pounds while digesting all these weight-loss research headlines from the Weight Loss channel
Newswise

As more families consider bariatric surgery a viable option to treat their child’s obesity, it is important to stay up-to-date on the latest research on weight loss. You can find the latest research on bariatric surgery and other weight loss options in the Weight Loss channel on Newswise, where journalists can find story ideas on this trending topic.

Newswise: Liver lobe-specific hydrodynamic gene delivery to baboons: A preclinical trial for hemophilia gene therapy
Released: 8-Jun-2023 1:20 PM EDT
Liver lobe-specific hydrodynamic gene delivery to baboons: A preclinical trial for hemophilia gene therapy
Niigata University

The research group of Professor Kamimura in Niigata University have applied the novel, liver lobe-specific hydrodynamic delivery procedure to primates (baboons) for the first time.

   
Released: 7-Jun-2023 11:55 AM EDT
PROSPECT trial expands treatment options for patients with resectable rectal cancer
American Society for Radiation Oncology (ASTRO)

The American Society for Radiation Oncology (ASTRO) Gastrointestinal Cancers Resource Panel issued a statement today on the PROSPECT clinical trial for patients with locally advanced rectal cancer. The statement clarifies that the trial did not explicitly conclude that radiation therapy should be omitted, contrary to many news reports, but rather that patients now have an additional treatment option to consider in discussions with their care team.

Released: 6-Jun-2023 6:50 PM EDT
How the gut microbiome responds to antibiotics
German Center for Infection Research (Deutsches Zentrum für Infektionsforschung - DZIF)

In a comprehensive metagenomic study, DZIF scientists Prof. Bärbel Stecher and Prof. Alice McHardy, together with an international research team, investigated the evolution of intestinal bacteria exposed to repeated disruptions by antibiotics.

Newswise: Start screenings at age 45 to prevent colorectal cancer, UT Southwestern experts advise
Released: 6-Jun-2023 11:05 AM EDT
Start screenings at age 45 to prevent colorectal cancer, UT Southwestern experts advise
UT Southwestern Medical Center

Colorectal cancer is on the rise among younger adults. According to the American Cancer Society, the proportion of cases among people under 55 increased from 11% in 1995 to 20% in 2019, and it is now the leading cause of cancer-related deaths for men younger than 50.

Newswise: Roswell Park Study May Provide Clues to Treating Colorectal Cancer More Effectively in Younger Patients
Released: 5-Jun-2023 3:00 PM EDT
Roswell Park Study May Provide Clues to Treating Colorectal Cancer More Effectively in Younger Patients
Roswell Park Comprehensive Cancer Center

While the incidence of colorectal cancer (CRC) has dropped significantly among older adults in recent years — a trend attributed to regular screening colonoscopies and lower smoking rates — the opposite is true for people born between 1981 and 1996, who have double the risk compared with people born in 1950. There’s an urgent need to identify more-effective therapies for those younger people: Approximately 58% of patients age 50 or under have advanced, distant disease at the time of diagnosis, and only 14% of that group will survive five years.

Newswise: Kiwi as Constipation Treatment and New Chronic Constipation Guideline in the June Issue of AJG
Released: 5-Jun-2023 9:00 AM EDT
Kiwi as Constipation Treatment and New Chronic Constipation Guideline in the June Issue of AJG
American College of Gastroenterology (ACG)

The June issue of The American Journal of Gastroenterology includes a new joint society guideline on pharmacological management of chronic idiopathic constipation and consumption of kiwifruit to relieve constipation.

Newswise: May Research Highlights
Released: 2-Jun-2023 3:05 AM EDT
May Research Highlights
Cedars-Sinai

A roundup of the latest medical discoveries and faculty news at Cedars-Sinai in May 2023.

Newswise: ASCO23: Sylvester Cancer Experts Available for Interviews on a Wide Range of Topics
Released: 1-Jun-2023 7:10 PM EDT
ASCO23: Sylvester Cancer Experts Available for Interviews on a Wide Range of Topics
Sylvester Comprehensive Cancer Center

In addition to presenting Sylvester Comprehensive Cancer Center research findings, Sylvester experts are available at ASCO to share perspectives on a wide variety of topics and studies ranging from breast cancer to sarcoma, prostate cancer, mesothelioma, melanoma, CNS tumors and more.

Newswise: Obesity drugs help patients lose weight regained years after bariatric surgery
Released: 1-Jun-2023 2:10 PM EDT
Obesity drugs help patients lose weight regained years after bariatric surgery
UT Southwestern Medical Center

Anti-obesity medications, including semaglutide (Ozempic and Wegovy), can effectively help patients manage weight regained after bariatric surgery, a study led by UT Southwestern Medical Center researchers shows.

Newswise: Hackensack Meridian Mountainside Medical Group welcomes Kulvir Nandra, colorectal surgeon
Released: 1-Jun-2023 12:50 PM EDT
Hackensack Meridian Mountainside Medical Group welcomes Kulvir Nandra, colorectal surgeon
Hackensack Meridian Health (Mountainside Medical Center)

Mountainside Medical Group has announced that Kulvir Nandra, M.D., has joined the practice, adding colorectal surgery to the medical group’s offerings.

Released: 1-Jun-2023 10:40 AM EDT
Tiny Video Capsule Shows Promise as an Alternative to Endoscopy
George Washington University

While ingestible video capsule endoscopes have been around for many years, the capsules have been limited by the fact that they could not be controlled by physicians. They moved passively, driven only by gravity and the natural movement of the body.

Released: 31-May-2023 11:05 AM EDT
Cleveland Clinic Research Suggests Metabolite Differences in Young-Onset Versus Average-Onset Colorectal Cancer
Cleveland Clinic

New research from Cleveland Clinic supports the theory that environmental exposures – such as red meat consumption and sugar intake – may play a role in the rising incidence of young-onset colorectal cancer. Researchers found that people younger than age 50 with colorectal cancer had lower levels of citrate, which is created in the process of converting food into energy, compared to older people diagnosed with colorectal cancer.

Newswise: Early toilets reveal dysentery in Old Testament Jerusalem
Released: 26-May-2023 12:35 PM EDT
Early toilets reveal dysentery in Old Testament Jerusalem
University of Cambridge

A new analysis of ancient faeces taken from two Jerusalem latrines dating back to the biblical Kingdom of Judah has uncovered traces of a single-celled microorganism Giardia duodenalis – a common cause of debilitating diarrhoea in humans.

   
Released: 25-May-2023 5:00 PM EDT
MD Anderson Research Highlights: ASCO 2023 Special Edition
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back. This special edition features presentations by MD Anderson researchers at the 2023 American Society of Clinical Oncology (ASCO) Annual Meeting.

   
Released: 25-May-2023 4:30 PM EDT
First Oral Medication to Treat Moderate-to-Severe Crohn’s Disease Completes Successful Phase 3 Trial and Earns FDA Approval
Mount Sinai Health System

Breakthrough study addresses unmet need in the treatment of Crohn’s disease and helps patients into clinical and endoscopic remission

Released: 22-May-2023 4:30 PM EDT
New Articles on Using Machine Learning to Predict Mammalian Acute Oral Toxicity and the Effects of Vinyl Chloride on Metabolism
Society of Toxicology

The May 2023 issue of Toxicological Sciences includes articles on profiling mechanisms that drive acute oral toxicity in mammals and its prediction via machine learning and how vinyl chloride enhances high-fat diet-induced proteome alterations in the mouse pancreas related to metabolic dysfunction.

   
Released: 22-May-2023 9:00 AM EDT
ACG and AGA Joint Guideline on Chronic Constipation Management
American College of Gastroenterology (ACG)

New guidelines for the management of chronic idiopathic constipation in adults are first to recommend magnesium oxide and senna as evidence-based treatments. This is a joint clinical practice guideline of the American College of Gastroenterology and the American Gastroenterological Association.

Newswise: Yale Cancer Center and Smilow Cancer Hospital Physicians and Scientists Presenting Latest Advances at 2023 ASCO Annual Meeting
Released: 18-May-2023 12:50 PM EDT
Yale Cancer Center and Smilow Cancer Hospital Physicians and Scientists Presenting Latest Advances at 2023 ASCO Annual Meeting
Yale Cancer Center/Smilow Cancer Hospital

Yale Cancer Center and Smilow Cancer Hospital scientists and clinicians will present new research at the 2023 Annual Meeting of the American Society of Clinical Oncology (ASCO), June 2nd to June 6th at McCormick Place in Chicago, Illinois. This year’s scientific program will feature more than 2,900 abstracts, covering all major diseases and research areas, including breast, lung, head and neck, gynecological, prostate, and gastric cancers.

Newswise: Un Estudio Proporciona Información Acerca de la Causa de la Enfermedad Intestinal Inflamatoria Grave
Released: 18-May-2023 10:05 AM EDT
Un Estudio Proporciona Información Acerca de la Causa de la Enfermedad Intestinal Inflamatoria Grave
Cedars-Sinai

Investigadores de Cedars-Sinai han identificado una variante genética que aumenta el riesgo de las personas de desarrollar la enfermedad de Crohn perianal, la manifestación más debilitante de la enfermedad de Crohn.

Released: 17-May-2023 2:00 PM EDT
Study finds cancer cells use a new fuel in absence of sugar
Michigan Medicine - University of Michigan

Researchers at the University of Michigan Rogel Cancer Center have discovered a new nutrient source that pancreatic cancer cells use to grow. The molecule, uridine, offers insight into both biochemical processes and possible therapeutic pathways. The findings, published in Nature, show that cancer cells can adapt when they don’t have access to glucose.

Newswise: Diagnosing inflammatory diseases with synthetic peptides
Released: 17-May-2023 1:45 PM EDT
Diagnosing inflammatory diseases with synthetic peptides
École Polytechnique Fédérale de Lausanne (EPFL)

Common inflammatory disorders such as ulcerative colitis and Crohn's disease can be diagnosed or monitored by measuring the protein calprotectin in stool samples, while serum levels of calprotectin could be used to monitor the inflammation status in rheumatoid arthritis.

Released: 16-May-2023 2:00 PM EDT
May is Melanoma and Skin Cancer Awareness Month. Keep up with the latest news on skin in the Dermatology channel
Newswise

Skin cancer is the most prevalent form of cancer in the United States, with over 5 million cases diagnosed annually. The Centers for Disease Control and Prevention reports that melanoma alone accounts for more than 8,000 deaths each year. Thankfully, skin cancer is highly preventable, making it crucial to prioritize protection. Below are some of the latest headlines in the Dermatology channel.

Released: 16-May-2023 12:20 PM EDT
Mortality and cost of severe acute pancreatitis keeps pressure on hospitals
Flinders University

Medical experts in Australasia have raised concern about the rising burden of severe acute pancreatitis (SAP) in intensive care units, with no change in mortality rates in these critically ill patients in almost two decades.

Newswise: Study Reveals How Fatty Liver Promotes Colorectal Cancer Spread
Released: 11-May-2023 5:40 PM EDT
Study Reveals How Fatty Liver Promotes Colorectal Cancer Spread
Cedars-Sinai

Investigators at Cedars-Sinai Cancer found that fatty liver, a condition closely associated with obesity, promotes the spread of colorectal cancer to the liver. Their study, published today in the peer-reviewed journal Cell Metabolism, details the process at the cellular level and could change the way doctors manage the disease in some patients.

Newswise: Brain-Belly Connection: Gut Health May Influence Likelihood of Developing Alzheimer’s
Released: 11-May-2023 3:50 PM EDT
Brain-Belly Connection: Gut Health May Influence Likelihood of Developing Alzheimer’s
University of Nevada, Las Vegas (UNLV)

UNLV study pinpoints 10 bacterial groups associated with Alzheimer’s disease, provides new insights into the relationship between gut makeup and dementia.

Newswise: Interactions between gut bacteria may limit antibiotics’ efficacy against C. difficile
4-May-2023 1:10 PM EDT
Interactions between gut bacteria may limit antibiotics’ efficacy against C. difficile
PLOS

A study publishing May 11th in PLOS Biology by Ophelia Venturelli at University of Wisconsin-Madison, USA, and colleagues suggests that between-species interactions within the gut microbiome may impact the efficacy of antibiotics aimed at treating C. difficile infections.

Newswise: Targeting uncontrolled inflammation may hold the key to treating therapy-resistant cancers
Released: 11-May-2023 1:15 PM EDT
Targeting uncontrolled inflammation may hold the key to treating therapy-resistant cancers
Van Andel Institute

Van Andel Institute scientists have pinpointed how a specific gene mutation triggers an inflammatory cascade that may drive development of treatment-resistant cancers.

Released: 9-May-2023 2:05 PM EDT
Long molecule of RNA essential to our GI tract’s ability to contract and move food along
Medical College of Georgia at Augusta University

A long molecule of RNA found in abundance in the healthy smooth muscle cells that give our blood vessels strength and flexibility is also essential to the continuous contraction that moves food through our gastrointestinal tract.

Newswise: Food additive nanoparticles could negatively affect your gut health
Released: 9-May-2023 8:55 AM EDT
Food additive nanoparticles could negatively affect your gut health
Binghamton University, State University of New York

Common food additives known as metal oxide nanoparticles may have negative effects on your gut health, according to new research from Binghamton University, State University of New York and Cornell University.

   
Newswise: AI Tool Predicts Future Pancreatic Cancer
6-May-2023 9:00 AM EDT
AI Tool Predicts Future Pancreatic Cancer
Harvard Medical School

An AI tool identified people at the highest risk for pancreatic cancer up to three years before actual diagnosis.

Newswise: Markey Cancer Center earns National Pancreas Foundation Center designation for treatment of pancreatic cancer
Released: 5-May-2023 3:25 PM EDT
Markey Cancer Center earns National Pancreas Foundation Center designation for treatment of pancreatic cancer
University of Kentucky

The University of Kentucky Markey Cancer Center has been recognized by the National Pancreas Foundation (NPF) as an approved NPF Center of Excellence. The designation is awarded after a rigorous audit review to determine that an institution's focus is on multidisciplinary treatment of pancreatic cancer, treating the “whole patient” with a focus on the best possible outcomes and an improved quality of life.

Newswise:Video Embedded live-event-for-may-3-study-of-rebyota-fecal-microbiota-on-patients-with-c-diff-infection
VIDEO
Released: 5-May-2023 10:25 AM EDT
Video and transcript: Study of fecal microbiota on patients with C. diff infection
Newswise

The researcher discusses the findings in a new study on the efficacy and safety of fecal microbiota (REBYOTA™), the first microbiota-based live biotherapeutic approved by the US FDA used to prevent recurrent Clostridioides difficile infection in adults.

Newswise: HIPEC Surgery Brings Advanced Abdominal Cancer Treatment to Smilow Cancer Hospital
Released: 5-May-2023 9:30 AM EDT
HIPEC Surgery Brings Advanced Abdominal Cancer Treatment to Smilow Cancer Hospital
Yale Cancer Center/Smilow Cancer Hospital

A technique that delivers high doses of heated chemotherapy directly to the abdominal cavity is a promising treatment for certain patients with Stage IV cancer. Hyperthermic intraperitoneal chemotherapy (HIPEC) kills cancer cells in the abdomen remaining after the surgical removal of tumors.

Newswise: How diet quality affects the gut microbiota to promote health
Released: 4-May-2023 5:45 PM EDT
How diet quality affects the gut microbiota to promote health
College of Agricultural, Consumer and Environmental Sciences, University of Illinois Urbana-Champaign

We know that eating a healthy diet affects body weight, cholesterol levels, and heart health. A new study from the University of Illinois focuses on another component: the role of diet in supporting a healthy gastrointestinal microbiota. The researchers conclude that following the Dietary Guidelines for Americans (DGA) promotes a gut microbiota composition that may support overall health.



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