Curated News: Grant Funded News

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New research from Washington University School of Medicine in St. Louis has identified key, naturally occurring biochemical components of a novel therapeutic food that is aimed at repairing malnourished children’s underdeveloped gut microbiomes.

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A previously mysterious small RNA molecule in mice is found to play a crucial role in gene expression, and may be the first identified member of a new class of regulatory RNAs.

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The International Wheat Genome Sequencing Consortium (IWGSC) is starting a two-year project, with funding from the U.S. National Science Foundation (NSF), to mine an untapped genetic resource for wheat improvement by sequencing the genomes of ancient varieties representing the worldwide diversity of bread wheat.

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Smoking shrinks the brain and effectively causes premature brain aging, according to a study by researchers at Washington University School of Medicine in St. Louis. Quitting smoking prevents further loss of brain tissue but doesn’t restore the brain to its original size.

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By making mammograms easy to schedule through personal online patient portals, Penn Medicine saw a significant increase in screenings for breast cancer

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In a study of more than 9,000 pregnant people from across the U.S., researchers at University of Utah Health found that cannabis exposure during pregnancy is associated with a composite measure of unhealthy pregnancy outcomes, especially low birth weight, and that higher exposure is associated with higher risks.

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Living through a historic pandemic while handling the stress of the first year of college sent one-third of students in a new study into clinical depression. That’s double the percentage seen in previous years of the same study.

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A woman who never developed Alzheimer's despite a strong genetic predisposition may hold the key to stopping the disease in its tracks.

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Psychologists and geographers at DePaul University are creating a new protocol to measure a new dimension of public spaces: Whether people of diverse backgrounds feel welcome in a community space.

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According to new predictions by La Jolla Institute for Immunology (LJI) researchers, if the new SARS-CoV-2 Pirola variant wants to evade T cells, it isn't doing a very good job.

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A beating heart makes for a formidable surgical arena, but a new robotic catheter could someday equip surgeons to operate in the cardiac environment with greater ease.

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What if a clinician could 3D print something through your skin, constructing an implant or replacement organ underneath layers of tissue? The world of medicine would be transformed: a host of surgical procedures, which come with a variety of risks, could be performed without ever lifting a scalpel.

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Post-surgery pain relief has shifted away from opioid-containing medications over the past seven years, but the downward trend has slowed since 2020, a new study shows.

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Researchers at the Icahn School of Medicine at Mount Sinai have identified an allergy pathway that, when blocked, unleashes antitumor immunity in mouse models of non-small cell lung cancer (NSCLC). And in an early parallel study in humans, combining immunotherapy with dupilumab—an Interleukin-4 (IL-4) receptor-blocking antibody widely used for treating allergies and asthma—boosted patients' immune systems, with one out of the six experiencing significant tumor reduction. The findings were described in the December 6 issue of Nature.

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Researchers from UC San Diego have shown unambiguous laboratory evidence that amino acids transported in the ice plumes of Saturn's moon, Eceladus, can survive impact speeds of up to 4.2 km/s, supporting their detection during sampling by spacecraft.

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A new study from researchers at Wake Forest University School of Medicine shows that dopamine release in the human brain plays a crucial role in encoding both reward and punishment prediction errors.

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Scientists have created tiny moving biological robots from human tracheal cells that can encourage the growth of neurons across artificial ‘wounds’ in the lab. Using patients’ own cells could permit growth of Anthrobots that assist healing and regeneration in the future with no need for immune suppression

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Adding a modular chimeric cytokine receptor to CAR T cells increased their efficacy. Learn how this modular system could improve brain and solid tumor therapy.

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Researchers from the McKelvey School of Engineering demonstrated monolithic 3D integration of layered 2D material into novel processing hardware for artificial intelligence (AI) computing.

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A new bacterial species discovered at the deep-sea hydrothermal vent site ‘Crab Spa’ provides a deeper understanding of bacterial evolution.

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A study from Washington University School of Medicine in St. Louis and Mid-America Transplant showed that the long-standing practice of treating deceased organ donors with thyroid hormone does not help preserve heart function, may cause harm and should be discontinued.

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New research from Andrew Hafenbrack, associate professor of management and organization in the University of Washington School of Business, and other institutions examines the impact of leadership style on prospective Black employees who apply for jobs in less-diverse companies.

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A Wayne State University College of Engineering professor has received a $2.65 million award from the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health to develop a novel filtration platform to improve an advanced drug delivery device to optimize diabetes insulin treatments.

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Nicole Hashemi and her students have been working for years to develop a "placenta-on-a-chip" that models how medicines, nutrients and other substances are passed from mother to fetus. A new, three-year, $350,000 National Science Foundation Mid-Career Advancement grant will allow Hashemi’s group to advance the project and explore commercialization.

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Acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS)—two related blood diseases that disproportionally strike older adults—are notoriously difficult to treat and associated with high relapse rates.

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In a new Cell study, scientists at La Jolla Institute for Immunology (LJI) and Massachusetts General Hospital, Harvard Medical School, show how a protein called IKAROS helps "weave" the genome.

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Dr. Nitin Agarwal, founding director of the Collaboration for Social Media and Online Behavioral Studies (COSMOS) Research Center at the University of Arkansas at Little Rock, has received $5 million from the Army Research Office to evaluate and defend against emerging socio-cognitive threats.

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Researchers create transistors combining silicon with biological silk, using common microprocessor manufacturing methods. The silk protein can be easily modified with other chemical and biological molecules to change its properties, leading to circuits that respond to biology and the environment

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A team of UC San Diego Herbert Wertheim School of Public Health and Human Longevity Science along with Kaiser Permanente Washington Health Research Institute researchers employed hearing tests and magnetic resonance imaging (MRI) to determine whether hearing impairment is associated with differences in specific brain regions and affects dementia risk.

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Immunotherapy using modified chimeric antigen receptor (CAR) T cells has greatly improved survival rates for relapsed and recurrent pediatric leukemia and lymphomas, but not brain and solid tumors.

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COVID-19 raced through nursing homes many times over the past few years. A new study shows the virus can leave a lasting impact – making the older adults who live in these facilities more dependent on staff to help them with basic daily activities for months after their infection.

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New digital tools that integrate patient health information have dramatically increased the rate of a highly effective, but underprescribed, cancer screen.

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Transistors — the tiny on-off switches inside microchips — have gotten smaller and smaller over the years, increasing computing power and enabling smaller devices. During that time, the copper wires that connect these switches have likewise shrunk but have also become less efficient.

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In a new study, researchers at the Georgia Institute of Technology investigated whether 25 rare gene variants known to be associated with inflammatory bowel disease (IBD) play a role in risk for African Americans.

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As part of a five-year, $3.9 million grant from the National Institutes of Health, Adriana Pérez, PhD, professor in the Department of Biostatistics and Data Science with UTHealth Houston School of Public Health in Austin, received a $1.9 million subcontract to determine the scope and drivers of low-value and unequal care for patients with Parkinson’s disease and Parkinson’s disease dementia.

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A tension-activated repair patch used in animal trials plugs holes in discs in the spine like car tire patches and could prevent further disease progression

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A new NIH award to Wayne State University aims to understand the early events around critical cell death that cause motor deficits, and ultimately, provide understanding for the development of much-needed therapies for prevention of motor deficits from congenital BH4 deficiency and CP.

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St. Jude scientists mapped the gene regulatory networks responsible for progressive differentiation states of tumor-infiltrating T cells, using a technology known as single-cell CRISPR screening to knock out or genetically perturb multiple genes potentially involved.

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A study showed that patient pain scores were a good predictor for opioid use, but younger patients and those who hadn’t used opioids before were less likely to take them

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The Department of Immunology and Immunotherapy and the Icahn Genomics Institute (IGI) at the Icahn School of Medicine at Mount Sinai have been awarded a $5 million grant from the National Cancer Institute (NCI) of the National Institutes of Health to establish a state-of-the-art center dedicated to the discovery and development of cutting-edge targets for cancer therapy.

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Cancer stem cells cause the aging of macrophages in mice with healthy immune systems, creating conditions for the formation of tumors.

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A five-year, $5 million grant has been awarded by the National Cancer Institute (NCI) to the UTHealth Houston Institute for Implementation Science to support research and training in implementation science, with a focus on improving cancer control efforts in Mexico and Latin America.

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A UC San Diego Herbert Wertheim School of Public Health and Human Longevity Science study reveals that online shopping for tobacco products increased the months following the California flavored tobacco ban and identified potential loopholes in tobacco control policies on e-commerce sales.

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Firearm deaths, injuries among young people exert massive physical, mental health burden on survivors and families. Financial costs also high; survivor health spending up by $35,000 in the year following injury, according to the analysis. Deaths and injuries likely to grow in coming years.

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A widespread Medicare program that aims to improve health care and lower costs by providing financial incentives to doctors and hospitals resulted in no improvements in mental health care, according to a study by researchers at Washington University School of Medicine in St. Louis and the Yale School of Public Health.

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The United States has the highest maternal mortality rate of any industrialized nation, a trend that has been accelerating for 20 years. But nearly two out of three maternal deaths are preventable, with cardiovascular disease (CVD) being the leading cause of death, said Kathryn Lindley, MD, holder of the Samuel S. Riven, MD, Directorship in Cardiology.