The Ohio State University, along with Bowling Green State University, has been selected to conduct a first-of-its-kind national, five-year study of health in same-gender couples.
Strong relationships between teachers, parents and students at schools has more impact on improving student learning than does financial support, new research shows. The study found that social capital had a three- to five-times larger effect than financial capital on reading and math scores in Michigan schools.
A cluster of factors may help predict which patients are likely to develop Clostridioides difficile, a potentially life-threatening disease commonly known as C. difficile or C. diff, a new study has found. And that could help in efforts to prevent infection, according to the researchers.
Insoo Hyun, PhD, and colleagues will identify ways of improving existing guidelines and ensuring professional accountability and responsibility in human-animal chimera research. The interdisciplinary bioethics project is supported by a three-year, $1.5 million grant from the National Human Genome Research Institute of the National Institutes of Health.
Rising sea levels driven by climate change make for salty soil, and that is likely to force about 200,000 coastal farmers in Bangladesh inland as glaciers melt into the world’s oceans, according to estimates from a new study.
Not much is known about how bipolar disorder (BD) affects people throughout their lives. Do women and men differ in the severity of their symptoms? Does a person’s age when a bipolar diagnosis is made have any bearing on how severe the symptoms are? How do other medical conditions affect symptoms of BD across the life-span? These questions and others like them are the focus of an international team of researchers, joined by Martha Sajatovic, MD, professor of psychiatry and of neurology at Case Western Reserve University School of Medicine, who has received a three-year, $600,000 grant from the International Society for Bipolar Disorders. She and her colleagues will develop the first-of-its-kind multi-national database that can be used to help researchers address questions about BD throughout the adult lifespan.
Men who want to have children in the near future should consider hitting the gym. A new study from researchers at The Ohio State University finds paternal exercise had a significant impact on the metabolic health of offspring well into their adulthood.
Cleveland Clinic researchers have found that better cardiorespiratory fitness leads to longer life, with no limit to the benefit of aerobic fitness. Researchers retrospectively studied 122,007 patients who underwent exercise treadmill testing at Cleveland Clinic between Jan. 1, 1991, and Dec. 31, 2014, to measure all-cause mortality relating to the benefits of exercise and fitness. The paper was published today in the Journal of the American Medical Association Network Open.
The Case Comprehensive Cancer Center has received a three-year, $3,194,947 grant from the National Cancer Institute to investigate colorectal and breast cancer health disparities. The grant is one of only four Specialized Programs of Research Excellence (SPORE) Planning Grant P20 awards given across the nation to address health disparities. It will provide the infrastructure for a new, comprehensive research program at Case Western Reserve University School of Medicine to study cancer health disparities at both molecular and population levels.
Biochemists, microbiologists, drug discovery experts and infectious disease doctors have teamed up in a new study that shows antibiotics are not always necessary to cure sepsis in mice. Instead of killing causative bacteria with antibiotics, researchers treated infected mice with molecules that block toxin formation in bacteria. Every treated mouse survived. The breakthrough study, published in Scientific Reports, suggests infections in humans might be cured the same way.
The American Board of Medical Specialties (ABMS), the leading not-for-profit organization overseeing physician certification in the United States, has awarded Nationwide Children’s Hospital its first-ever ABMS Multi-Specialty Portfolio Program™ (Portfolio Program) Outstanding Achievement in Quality Improvement Award.
Research scientists around the world are now able to investigate the structural, cellular, and developmental intricacies of the human brain using bioengineered stem cell-based models called organoids. But the ethics to help guide researchers and regulators lag behind the technological capability to “grow” brains in a petri dish. That is about to change as a group of bioethicists and scientists chart the unexplored territory of neuroethics, which is quickly emerging from the ability to bioengineer models of the brain. The study, called “The Brainstorm Project,” will be led by Insoo Hyun, PhD, professor of bioethics at Case Western Reserve University School of Medicine.
Dr. Andrew Sloan of University Hospitals Seidman Cancer Center becomes first neurosurgeon to use 5-ALA in the U.S. following its FDA approval for brain cancer surgery.
Chemists at The Ohio State University have developed a new and improved way to generate molecules that can enable the design of new types of synthetic drugs.
Many breast cancer drugs block estrogen receptors inside cancer cells. Blocking the receptors early in disease progression staves off metastasis. But most patients with advanced disease eventually develop drug resistance, leaving doctors desperate for alternatives. Now, researchers from Case Western Reserve University School of Medicine have uncovered a previously uncharacterized, bridge-like structure within the human estrogen receptor that could serve as a valuable new drug target. In Nature Communications, researchers describe a “burning the bridge” strategy to disrupting the estrogen receptor, and how to screen breast cancer drugs designed to do it.
A Baldwin Wallace University statewide survey reveals that the Ohio governor’s race is a statistical tie. In a two-way race, DeWine holds a 42% to 40% advantage over Democrat Richard Cordray among voters stating a preference. More than 18% say they remain unsure about how they will vote for governor.
A Baldwin Wallace University statewide survey reveals that the Ohio governor’s race is a statistical tie. In a two-way race, DeWine holds a 42% to 40% advantage over Democrat Richard Cordray among voters stating a preference. More than 18% say they remain unsure about how they will vote for governor.
Researchers have developed designer molecules that may one day be able to seek out and trap deadly nerve agents and other toxic compounds in the environment – and possibly in humans.
A team of nurses and physicians has received a four-year, $3 million grant from the National Heart, Lung, and Blood Institute to extend traditional HIV treatment protocols to improve the cardiovascular health of people living with HIV.
Next time you’re stung by a wasp or a honeybee, consider the elegantly designed stinger that caused you so much pain. In a new study, researchers found that the stingers of the two species are about five times softer at the tip than at the base to make it easier to pierce your skin.
Wenquan Zou, MD, PhD, and his collaborator, Qingzhong Kong, PhD, of Case Western Reserve University School of Medicine, have been awarded $2.9M from the National Institutes of Health to extend their previous path-breaking finding of skin prions of these devastating diseases.
The esports industry is growing quickly and The Ohio State University is leading in its development by forming the most comprehensive esports program to date.
Preterm birth remains a global epidemic linked to a lifetime of potential health complications. It also is difficult to study in living creatures—especially the uniquely precise biology of preterm birth in humans. Researchers report in PLoS Biology successfully inserting just enough human DNA into transgenic laboratory mice that it allowed the team to study a unique part of human pregnancy compared to other animals.
Efthimios Parasidis, associate professor of law and public health at The Ohio State University, talks about whether or not it's a good idea for companies to mandate that their employees get a flu shot.
Status of House Bill 193: https://www.legislature.ohio.gov/legislation/legislation-status?id=GA132-HB-193
In two newly published papers, a scientific team at Case Western Reserve University School of Medicine reports on the discovery and implementation of a new, more efficient method for generating an important brain stem cell in the laboratory. The findings pave the way for greater understanding of the underlying mechanisms of neurological disorders of myelin and ultimately, possible new treatment and prevention options. The studies were published in the September issues of Nature Communications and Stem Cell Reports.
Physicians who specialize in a devastating and aggressive immune disorder called hemophagocytic lymphohistiocytosis (HLH) report in a new study that extra care should be taken to ensure an HLH diagnosis doesn’t obscure possible underlying cancers. They caution in the journal Pediatric Blood & Cancer that expediting HLH treatment may miss underlying malignancies that could end up being fatal to the patient.
A low-cost, easy-to-replicate test for tuberculosis might help developing nations better identify and treat the infectious and sometimes deadly disease, new research suggests.
Public trust in science depends on renewed efforts to protect the integrity of research, according to speakers at a Sept. 23 Ohio State University summit. Experts emphasized the need for a “culture of trust” around research and pledged to find ways to support that culture.
There’s a surprising upside to the fact that many people edit their selfies on Instagram and other social media sites to enhance their appearance. A new study found that when women believed that selfies of thin and sexualized women had been edited, viewing these images had less negative impact on one aspect of their mental health.
The odds of a black or Hispanic patient visiting an outpatient dermatologist are about half that of a white patient with the same skin condition, according to a new study in JAMA Dermatology. Patients most likely to receive outpatient dermatologic services in the study were white, educated women. The findings are among several that describe disparities in the use of outpatient dermatology services.
Researchers at the Case Western Reserve University School of Dental Medicine found that smoking also weakens the ability for pulp in teeth to fight illness and disease.
Two recent studies in the journal Leukemia present a new approach for bone marrow donation and transplant that preclinical laboratory tests suggest could make the life-saving procedure safer and more effective for patients. Researchers say their studies demonstrate that use of an experimental drug called CASIN in laboratory mice results in higher efficiency when harvesting blood stem cells from donors and less toxicity in transplant recipients.
Almost 16 percent of college students say they misuse prescription stimulants, often in the quest for better grades, a new survey of U.S. undergraduate, graduate and professional students has found.
Researchers around the world are exploring the gut/brain axis in the quest for knowledge about mood disorders such as depression, neurodegenerative diseases including Alzheimer’s and chronic conditions such as Crohn’s disease.
Scientists working to bioengineer the entire human gastrointestinal system in a laboratory now report using pluripotent stem cells to grow human esophageal organoids. The newly published research in the journal Cell Stem Cell is the first time scientists have been able to grow human esophageal tissue entirely from pluripotent stem cells (PSCs), which can form any tissue type in the body.
Certain genes that code for proteins have long been known to contribute to cancer progression. But in a frame shift, researchers from Case Western Reserve University School of Medicine recently found that non-coding genes also contribute to the development and spreading of the disease, one of the first known examples of researchers doing so. The lead author of the study reporting this finding, Ahmad Khalil, PhD, assistant professor of genetics and genome sciences at Case Western Reserve School of Medicine, has been awarded a five-year, $1.85 million grant from the National Institutes of Health to build on the discovery, with an eventual aim of pinpointing additional targets for cancer-fighting treatments.
With an estimated 1.6 million people in the U.S. dealing with inflammatory bowel disease (IBD), physicians can have a hard time telling which newly diagnosed patients have a high risk of severe inflammation or what therapies will be most effective. Now researchers report in the journal JCI Insights finding an epigenetic signature in patient cells that appears to predict inflammation risk in a serious type of IBD called Crohn’s disease.
This is a story about something rare in health psychology: a treatment that has gone from scientific discovery, through development and testing, to dissemination and successful implementation nationwide.
A Baldwin Wallace University survey reveals that a strong majority of likely Ohio voters have magnified the significance of the 2018 midterm elections, with nearly 58% saying that voting this November is more important than in previous midterms.
Case Western Reserve University School of Medicine has received a three-year, $1,118,556 grant from the National Heart, Lung, and Blood Institute of the National Institutes of Health to investigate a new imaging approach for diagnosing peripheral arterial disease, a common and potentially serious circulatory problem. More than 200 million people worldwide suffer from the condition.
Many women in doctoral degree programs in fields like engineering and physics are in a class of their own – and that’s not a good thing. A new study found that the fewer females who enter a doctoral program at the same time, the less likely any one of them will graduate within six years.