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Released: 2-Aug-2018 2:05 PM EDT
New Light Shed On Relationship Between Calorie-burning Fat and Muscle Function
Beth Israel Lahey Health

Endocrinologists at Beth Israel Deaconess Medical Center (BIDMC) have shown for the first time that brown fat can exert control over skeletal muscle function.

1-Aug-2018 9:30 AM EDT
Hearing Class
Harvard Medical School

A new study finds that the class of neurons responsible for transmitting information from the inner ear to the brain is composed of three molecularly distinct subtypes. The findings could inform efforts to develop therapeutic strategies to treat or protect against hearing loss.

Released: 2-Aug-2018 10:00 AM EDT
Dana-Farber Launches Chinese-Language Website
Dana-Farber Cancer Institute

Dana-Farber Cancer Institute launches a new Chinese-language website.

2-Aug-2018 5:00 AM EDT
Muscle “Switch” May Control the Benefits of Exercise
Joslin Diabetes Center

Studying lab animals and humans, researchers at Joslin Diabetes Center discovered that a protein called JNK helps to drive response to exercise. If JNK is activated during exercise, the researchers say, that stimulates skeletal muscle growth. If it’s not activated, muscles improve their adaptation for endurance and aerobic capacity.

30-Jul-2018 4:05 PM EDT
Scientists Identify New Cell Type in Human Lungs
Harvard Medical School

Researchers have discovered a new, rare type of cell in the human airway. These cells appear to be the primary source of activity of the gene which causes cystic fibrosis.

   
Released: 1-Aug-2018 12:05 PM EDT
BIDMC Study Determines Risk Factors for Opioid Misuse
Beth Israel Lahey Health

• When opioids are prescribed following surgery, approximately four percent of the general patient population will continue using opioids for an extended time period • Race and household income were not significant risk factors for prolonged opioid use • Physicians’ prescribing practices may influence patient risk • Patients in the worker’s compensation setting experienced the highest rates of prolonged opioid use

Released: 1-Aug-2018 12:00 PM EDT
After 60 Years, Scientists Uncover How Thalidomide Produced Birth Defects
Dana-Farber Cancer Institute

More than 60 years after the drug thalidomide caused birth defects in thousands of children whose mothers took the drug while pregnant, scientists at Dana-Farber Cancer Institute have solved a mystery that has lingered ever since the dangers of the drug first became apparent: how did the drug produce such severe fetal harm?

Released: 31-Jul-2018 10:00 AM EDT
Tufts Ramnath Subbaraman selected to receive Doris Duke Charitable Foundation award
Tufts University

Ramnath Subbaraman, a Tufts University School of Medicine assistant professor of public health and community medicine, has been selected to receive a 2018 Clinical Scientist Development Award from the Doris Duke Charitable Foundation. The award supports his research to improve tuberculosis care in India.

Released: 26-Jul-2018 4:45 PM EDT
Calling All Baby Boomers: Get Tested for Hepatitis C
Beth Israel Lahey Health

Michael Curry, MD, Section Chief, Hepatology at Beth Israel Deaconess Medical Center, suggests that baby boomers should get tested for Hepatits C.

Released: 26-Jul-2018 3:05 PM EDT
BIDMC Research Brief Digest: July 2018
Beth Israel Lahey Health

A monthly roundup of research briefs showcasing recent scientific advances led by Beth Israel Deaconess Medical Center faculty.

Released: 26-Jul-2018 12:05 AM EDT
BIDMC Researchers ID the Brain's Claustrum as Likely Origin of Parkinsonism's Tremors, Rigidty and Slowed Movement
Beth Israel Lahey Health

Parkinsonism – slowed movement, muscle rigidity and tremor – is a classic set of neurological symptoms most often seen in patients with Parkinson’s disease. Because neuron loss in the substantia nigra – a region of the brain associated with motor planning – is the hallmark characteristic of Parkinson’s disease, parkinsonism has long been thought to originate there. However, parkinsonism can occur in patients who have other conditions that leave the substantia nigra intact, making the true source of the suite of symptoms a mystery.

Released: 24-Jul-2018 4:45 PM EDT
Does Sparkling Water Hydrate You?
Beth Israel Lahey Health

Mark Zeidel, MD, Chair of the Department of Medicine at Beth Israel Deaconess Medical Center, clears up the myths and facts around sparkling water.

Released: 23-Jul-2018 4:00 PM EDT
Scientists Develop New Materials That Move in Response to Light
Tufts University

Researchers have developed magnetic elastomeric composites that move in different ways when exposed to light, raising the possibility that these materials could enable a wide range of products that perform simple to complex movements, from tiny engines and valves to solar arrays that bend toward the sunlight.

Released: 23-Jul-2018 10:05 AM EDT
Study suggests ways DPP-4 inhibitor might prevent kidney disease
Joslin Diabetes Center

Researchers have long sought drugs that could help to prevent diabetic kidney disease (DKD), which afflicts about 40% of people with type 2 diabetes. Among the current contenders are a class of diabetes management drugs known as DPP-4 inhibitors. Scientists at Joslin Diabetes Center now have shown that in mouse models of diabetic kidney disease, the DPP-4 inhibitor linagliptin produces two signs of prevention against kidney damage.

17-Jul-2018 9:00 AM EDT
Study Finds Melanoma Biomarkers Predicting Checkpoint Blocker Response
Dana-Farber Cancer Institute

Scientists at Dana-Farber/Brigham and Women’s Cancer Center (DF/BWCC) have identified biomarkers in melanoma that could help tailor immunotherapy treatments to maximize the benefits for patients while reducing the likelihood of severe side effects.

Released: 17-Jul-2018 4:45 PM EDT
Avoiding Sunburns This Summer
Beth Israel Lahey Health

Suzanne Olbricht, MD, Chief of Dermatology at Beth Israel Deaconess Medical Center, shares tips for avoiding sunburns.

13-Jul-2018 3:30 PM EDT
From the Lab to the Real World: Program to Improve Elderly Mobility Feasible in Community
Tufts University

A pilot study led by researchers from Tufts University and conducted at the Somerville Council on Aging in Somerville, Mass., translated for the first time the physical activity benefits of the Lifestyle Interventions and Independence for Elders study in a community setting.

   
Released: 13-Jul-2018 1:05 PM EDT
The Love Lives of Fruit Flies
Harvard Medical School

New study reveals that a male fruit fly’s decision to court or ignore a female stems from the convergence of motivation, perception and chance that affects the balance of excitatory versus inhibitory signals in the brain to influence decision making. Findings may yield insights about addiction disorders, depression.

12-Jul-2018 4:45 PM EDT
Speaking Up for Patient Safety
Beth Israel Lahey Health

In a new study, a team led by clinician-researchers at Beth Israel Deaconess Medical Center (BIDMC) surveyed family members and patients with recent ICU experiences about their willingness to speak up about care concerns to medical providers.

Released: 12-Jul-2018 2:05 PM EDT
Hospitals May Take Too Much of the Blame for Unplanned Readmissions
Beth Israel Lahey Health

A new study out of Beth Israel Deaconess Medical Center reveals that the preventability of readmissions changes over time: readmissions within the first week after discharge are often preventable by the hospital, whereas readmissions later are often related to patients’ difficultly accessing outpatient clinics.

9-Jul-2018 5:45 PM EDT
Guardian of the Cell
Harvard Medical School

Scientists have defined the structure and key features of a human immune-surveillance protein that guards against cancer and bacterial and viral infections The identification of two human-specific variations in the protein closes a critical knowledge gap in immunology and cancer biology The variations explain why the human protein is more precise and more selective than mammalian forms of the protein and why it targets certain types of DNA but ignores others The findings can inform the design of more precisely targeted immune therapies against cancer and a range of immune-mediated diseases

Released: 12-Jul-2018 10:30 AM EDT
Bertarelli Foundation Invests in Promise of Translational Research to Tackle Sensory Disorders
Harvard Medical School

The Bertarelli Foundation has announced that it is redoubling its investment in this area of research, with a gift of $6.35 million to Harvard Medical School (HMS) to build on the previous successes of the Bertarelli Program in Translational Neuroscience and Neuroengineering.

11-Jul-2018 10:30 AM EDT
Rise of the Clones
Harvard Medical School

Researchers discover new clues about a recently identified blood cell condition known as clonal hematopoiesis, implicated in hematologic cancers, cardiovascular illness Surprisingly, the study reveals that inherited genetic variants can drive the condition by fueling additional mutations later in life The findings can help inform ways to gauge disease risk based on specific mutations, develop strategies to avert disease Clonal hematopoiesis is estimated to affect more than 1 in 10 people older than 65

Released: 10-Jul-2018 3:40 PM EDT
Barbara B. Kahn, MD Receives 2019 FASEB Excellence in Science Award
Beth Israel Lahey Health

Barbara Kahn, MD, Vice Chair for Research Strategy in the Department of Medicine at Beth Israel Deaconess Medical Center (BIDMC), will receive the 2019 FASEB Excellence in Science Award.

Released: 10-Jul-2018 3:35 PM EDT
Researchers Prevent, Reverse Renal Injury by Inhibiting Immune-Regulating Molecule
Beth Israel Lahey Health

Study findings from a team of scientists led by George C. Tsokos, MD, Chief of the Division of Rheumatology at BIDMC, overturn conventional wisdom about kidney disease.

2-Jul-2018 4:30 PM EDT
In End-of-Life Cancer Care, Geography May Be Destiny
Harvard Medical School

Research reveals dramatic geographic differences in end-of-life care spending across the United States. Spending variations stemmed from doctors’ beliefs about end-of-life care and style of practice and from availability of health care services. Patient beliefs and preferences did not contribute to spending differences. Health care spending in the last month of life for patients with end-stage cancer in some regions is twice as high as that in other regions. The additional spending is wasteful and possibly harmful.

Released: 9-Jul-2018 9:00 AM EDT
National School Food Policies Have Potential to Improve Health Now and Later
Tufts University

Providing free fruits and vegetables and limiting sugary drinks in schools could have positive health effects in both the short- and long-term, finds a new Food-PRICE study led by researchers from the Friedman School of Nutrition Science and Policy at Tufts University.

   
5-Jul-2018 4:00 PM EDT
Preventative HIV Vaccine Candidate Triggers Desired Immune Responses in Humans and Monkeys, and Protects Monkeys from Infection
Beth Israel Lahey Health

In a new study, published July 6 in The Lancet, a team of researchers led by Beth Israel Deaconess Medical Center's Dan H. Barouch, MD, PhD, in collaboration with Janssen Vaccines & Prevention and other partners, evaluated a series of preventative HIV vaccine regimens in uninfected human volunteers in five countries. In a similarly designed study, Barouch and colleagues tested the same vaccine for its ability to protect rhesus monkeys challenged with an HIV-like virus from infection. The findings showed the vaccines induced robust and comparable immune responses in humans and monkeys and protected monkeys against acquisition of infection.

Released: 6-Jul-2018 3:30 PM EDT
Savory Foods May Promote Healthy Eating Through Effects on the Brain
Beth Israel Lahey Health

Researchers at Beth Israel Deaconess Medical Center have found that consuming a broth rich in umami—or savory taste—can cause subtle changes in the brain that promote healthy eating behaviors and food choices, especially in women at risk of obesity.

29-Jun-2018 4:15 PM EDT
Smart Bandages Designed to Monitor and Tailor Treatment for Chronic Wounds
Tufts University

A “smart” bandage is designed to monitor the condition of chronic wounds and deliver drug treatments to improve chances of healing. While the bandages remain to be assessed in a clinical context, the research is aimed at transforming bandaging from a passive to an active treatment paradigm.

Released: 2-Jul-2018 2:05 PM EDT
Scientists Visualize the Connections Between Eye and Brain
Beth Israel Lahey Health

In this study, BIDMC researchers developed a means of tracking the activity of the far-reaching ends of retinal neurons (called boutons) as they deliver visual information to the thalamus, a brain region involved in image processing.

   
Released: 2-Jul-2018 10:05 AM EDT
Olin Receives $400,000 Gift for Exploring Innovation in Engineering Education
Franklin W. Olin College of Engineering

Olin Receives $400,000 Gift for Exploring Innovation in Engineering Education

   
Released: 29-Jun-2018 1:05 PM EDT
How to Avoid Migraine Triggers
Beth Israel Lahey Health

If you’ve ever had a migraine, you know it’s different from a typical tension headache. Check out these tips from neurologist Sait Ashina, MD, for avoiding common migraine triggers.

Released: 28-Jun-2018 5:05 PM EDT
BIDMC Research Brief Digest: June 2018
Beth Israel Lahey Health

A monthly roundup of research briefs showcasing recent scientific advances led by Beth Israel Deaconess Medical Center faculty.

Released: 28-Jun-2018 2:05 PM EDT
New Study Reveals the Function of a Mysterious Component of the Inner Ear
Harvard Medical School

A new study finds that a mysterious component of the inner ear acts as a pressure-relief valve, formed by a thin barrier of cellular projections that opens and closes to regulate the release of inner ear fluid.

   
22-Jun-2018 9:05 AM EDT
How the Flu Virus Builds a Better Mousetrap
Tufts University

For the first time, scientists have directly visualized real-time structural changes in the surface protein of the influenza virus that may help the virus fuse with and enter target cells before hijacking them. Single molecules of the protein were found to stretch toward target cells, then refold and try again 5 to 10 times per second. The discovery may help develop more effective vaccines and better understand other viruses, including Ebola, HIV, and SARS.

   
22-Jun-2018 12:00 PM EDT
When It Comes to Gonorrhea, Gender Matters
Tufts University

In a new pilot study, a team led by researchers from Tufts University School of Medicine conducted the first full comparison of gonococcal gene expression and regulation in both men and women, identifying gender-specific signatures in infection and in antibiotic resistance genes.

Released: 25-Jun-2018 12:10 PM EDT
Aimee Shen of Tufts Medical School granted PATH award from Burroughs Wellcome Fund
Tufts University

Microbiologist Aimee Shen at Tufts University School of Medicine is one of 12 new recipients nationwide of the Burroughs Wellcome Fund 2018 Investigators in the Pathogenesis of Infectious Disease (PATH) award for her research on Clostridium difficile.

     
Released: 22-Jun-2018 10:05 AM EDT
Olin and Emerson Colleges Collaborate on Remaking Education Event
Franklin W. Olin College of Engineering

Olin and Emerson Colleges have joined forces to produce a groundbreaking one-day event—Remaking Education—designed to raise awareness of the need for change in education, and to inspire action among leaders in education, business, and the non-profit world. T

Released: 21-Jun-2018 4:30 PM EDT
Warren Alpert Foundation Honors Pioneering Discoveries in Cystic Fibrosis
Harvard Medical School

The 2018 Warren Alpert Foundation Prizehas been awarded to five scientists for transformative discoveries in the fields of genetics, physiology, pulmonology and pharmacology that have led to the development of life-altering precision-targeted treatments for the devastating multiorgan disease cystic fibrosis (CF).

Released: 20-Jun-2018 4:30 PM EDT
Harvard Medical School Announces 2018 Media Fellowship: The Science of Pain
Harvard Medical School

Harvard Medical School’s Media Fellowship program, now entering its 21st year, is accepting applications for its fall 2018 session.

Released: 20-Jun-2018 1:05 PM EDT
Influx of New Faculty Join Olin College of Engineering
Franklin W. Olin College of Engineering

Olin College announces nine new faculty will join the College over the next two years.

Released: 20-Jun-2018 1:05 PM EDT
East Boston Launching Novel Neighborhood-scale Air Quality Monitoring Network
Franklin W. Olin College of Engineering

Olin College and Aerodyne plan to install eight to twelve ARISense instruments around East Boston, at a fraction of the cost of a single EPA monitoring site.

     
Released: 20-Jun-2018 1:05 PM EDT
Hendren Awarded Arts Culture Grant
Franklin W. Olin College of Engineering

Sara Hendren, an artist, designer and researcher-in-residence at Olin College has been awarded an Artist Fellowship in non-fiction writing from the Massachusetts Cultural Council.

   
Released: 20-Jun-2018 12:05 PM EDT
MIT Study Names Olin College World Leader in Engineering Education
Franklin W. Olin College of Engineering

A new MIT study has named Olin College of Engineering, along with MIT, as the top leaders in engineering education globally.

   
Released: 20-Jun-2018 12:05 PM EDT
Olin Names Mimi Onuoha First "Creative-in-Reference" as Part of Initiative to Better Integrate Arts and Humanities with STEM Education
Franklin W. Olin College of Engineering

Brooklyn-based artist and researcher Mimi Onuoha has been named the first “Creative-in-Reference” at Olin College, a position established as part of a multi-step $900,000 grant from the Andrew W. Mellon Foundation designed to better integrate the arts and humanities within a STEM education.

   
Released: 20-Jun-2018 11:05 AM EDT
Sara Hendren Named 2018 Carey Institute Fellow
Franklin W. Olin College of Engineering

The Carey Institute for Global Good has named Sara Hendren a Logan Nonfiction Program Fellow. Hendren is a designer and researcher in residence at Olin College and is writing a book about the unexpected places where disability is at the heart of design, to be published by Riverhead Books

   
Released: 18-Jun-2018 5:05 PM EDT
Embracing Respect and Dignity as The Next Frontier in Preventing Patient Harm
Beth Israel Lahey Health

A group of national leaders in quality and safety, led by researchers at Beth Israel Deaconess Medical Center (BIDMC), has developed a consensus statement – a document developed by an independent panel of experts about a particular issue – intended to embrace an expanded definition of patient harm that includes non-physical harm, with the goal of improving the practice of respect across the continuum of care.

13-Jun-2018 3:05 PM EDT
Microglia Protect Sensory Cells Needed for Vision After Retinal Detachment
Massachusetts Eye and Ear

A research team at Massachusetts Eye and Ear has shown that microglia, the primary immune cells of the brain and retina, play a protective role in response to retinal detachment.



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