Hidden way for us to feel touch uncovered by Imperial researchers
Imperial College LondonPreviously, touch was thought to be detected only by nerve endings present within the skin and surrounding hair follicles.
Previously, touch was thought to be detected only by nerve endings present within the skin and surrounding hair follicles.
Researchers have discovered a protein that seals plant roots to regulate the uptake of nutrients and water from the soil, the discovery could help develop climate proof crops that require less water and chemical fertilizers
A novel replacement strategy termed GE x HDR 2.0: Find and Replace, developed by researchers from Bar-Ilan University and described in published today in Nature Communications, combines CRISPR-Cas9-mediated genome editing with recombinant adeno-associated serotype 6 (rAAV6) DNA donor vectors to precisely replace the RAG2 coding sequence while preserving regulatory elements.
Irvine, Calif., Oct. 26, 2023 — A study from the University of California, Irvine has revealed that in 2022, 38 North American businesses used direct-to-consumer advertising to promote unproven stem cell interventions and exosome products as purported treatments and preventatives for COVID-19. Collectively, these organizations operated or facilitated access to 60 clinics – with 24 in the U.
New WSU bioreactor rapidly grows cancer-killing cells for immunotherapy
Biological mechanisms found in fruit flies could inform efforts against disease-spreading mosquitos.
Harnessing new advances in genomic surveillance technology could help detect the rise of deadly ‘superbugs’
A research team from the UC Davis Comprehensive Cancer Center has identified a crucial epitope (a protein section that can activate the larger protein) on the CD95 receptor that can cause cells to die.
The quintessential female sex hormone estrogen stimulates cells that line blood vessels to deliver insulin to muscles, lowering blood sugar and protecting against Type 2 diabetes, UT Southwestern Medical Center researchers report. The findings, published in Nature Communications, could eventually lead to new therapies for Type 2 diabetes, a disease that affects hundreds of millions of people around the globe and continues to grow more prevalent.
Stimulating muscle fibers with magnets causes them to grow in the same direction, aligning muscle cells within tissue, Massachusetts Institute of Technology (MIT) and Boston University investigators report October 20 in the journal Device.
A UC Davis study shows the first-in-human imaging of the body’s CD8 T cell immune response to COVID-19 infection in recovering patients.
New protein folding models could lead to new medicines and industrial processes
Scientists at Tufts University School of Medicine have developed a genome-scale metabolic model or “subway map” of key metabolic activities of the bacterium that causes Lyme disease.
A team of researchers from the National University of Singapore has engineered an innovative magnetic wound-healing gel that promises to heal diabetic wounds three times faster, reduce the rates of recurrence, and in turn, lower the incidents of limb amputations. The innovative magnetic hydrogel, which contains skin cells for healing as well as magnetic particles, takes a comprehensive ‘all-in-one’ approach to wound healing, accelerating the process on several fronts. To maximise therapeutic results, a wireless external magnetic device is used to activate skin cells and accelerate the wound healing process. A patent has been filed for this innovation.
There is no cure or FDA-approved therapy for acute respiratory distress syndrome, which has a high rate of mortality. Inflammation plays a major role in developing ARDS. Researchers at Ohio State University developed therapeutic nanocarriers using mice skin cells, which reduced inflammation in their lungs.
Researchers at Kyushu University have discovered that turning brain immune cells into neurons successfully restores brain function after stroke-like injury in mice. These findings, published on October 10 in PNAS, suggest that replenishing neurons from immune cells could be a promising avenue for treating stroke in humans.
Scientists have breathed new life into the study of a protein with an outsized link to human cancers because of its dangerous mutations, using advanced research techniques to detect its hidden regions.
Different strains of E.coli can outcompete one another to take over the gut, a new study reveals.
Researchers at University of California San Diego have discovered a process in which liver cells share molecules in order to multiply under conditions that would ordinarily suppress cell proliferation. They also found evidence that this process occurs in various types of cancer cells.
Scientists from Immanuel Kant Baltic Federal University on the base of literary sources have described in detail the connection between intracellular processes in mitochondria and metabolic disorders in human’s organism that lead to obesity and cardiovascular diseases.
Researchers discover a new family of Gram-negative bacterial enzymes related to infection capability
In a new study published in Cell Chemical Biology, Moffitt Cancer Center researchers demonstrate this, showing that the ROS1 inhibitor lorlatinib has activity against an additional protein called PYK2. The team also reveals the mechanisms of this inhibition.
FASEB Conferences On-Demand will ensure that biological and biomedical scientists can stay up to date on the latest advances—wherever and whenever.
Dendritic cells are key orchestrators of the immune response, but most vaccination strategies don’t effectively target them. NIBIB-funded researchers have developed biodegradable nanoparticles that are designed to deliver mRNA cargo to dendritic cells in the spleen.
A new study has unravelled a crucial link between how cancer cells cope with replication stress and the role of Taurine Upregulated Gene 1 (TUG1). By targeting TUG1 with a drug, the researchers were able to control brain tumor growth in mice, suggesting a potential strategy to combat aggressive brain tumors such as glioblastomas.
Synthetic biologists at Columbia Engineering report today a new approach to attacking tumors. They have engineered tumor-colonizing bacteria (probiotics) to produce synthetic targets in tumors that direct CAR-T cells to destroy the newly highlighted cancer cells.
Reversing historical patterns, new findings led by researchers at the American Cancer Society show higher lung cancer incidence in women than in men has not only continued in adults younger than 50 years, but now extends to women 50 to 54 years of age in the United States. The findings are published today in the Journal of the American Medical Association (JAMA) Oncology.
Researchers at McMaster and the University of Guelph have discovered a convenient new way to track levels of omega-3 fatty acids in the bloodstream, making it much easier to access information that is critical to cardiovascular and cognitive health, but which has previously been challenging to gather. While the human body can generate most of the fats it needs, it cannot produce adequate levels of omega-3 fatty acids and must obtain them from dietary sources. Two key omega-3 fatty acids, called EPA (eicosatetraenoic acid), and DHA (docosahexaenoic acid), can be derived only from certain sources, such as fish, seafood, enriched foods, and supplements, but measuring how much gets into the blood has been both difficult and invasive.
The Association for Molecular Pathology has published best practice recommendations for validating and reporting clinical circulating tumor DNA (ctDNA) or liquid biopsy assays and their related scientific publications.
Basic Research Findings by Johns Hopkins Scientists Focus on Gene Sequencing, Hearing Loss and a Brain Disorder
Michael Berger, PhD, has been awarded a grant by The Israel Cancer Research Fund (ICRF) and the Cancer Research Institute (CRI).
Investigators have been awarded a grant to find a better way to protect muscle mass in patients. Muscle mass plays a critical role in quality of life and cancer survival.
The University of Texas MD Anderson Cancer Center will host its annual Leading Edge of Cancer Research Symposium Nov. 16-17, 2023, featuring presentations and discussions on genomics, immunity and inflammation, computational approaches for spatial biology, and emerging technologies that are driving the next wave of cancer breakthroughs.
A new study led by Yale scientists shows that the activity of a portion of a human papillomavirus (HPV) protein does not depend on its amino acid sequence or composition.
In a new article published today in Science Translational Medicine, a team of Moffitt Cancer Center researchers, in collaboration with NFlection Therapeutics and researchers at Stanford University, reports the identification of a new drug, NFX-179, that can be applied to the skin and was shown to prevent the development of cutaneous squamous cell carcinoma in pre-clinical models.
Through a novel approach detailed in Nature, a massive computational analysis of microbiome datasets more than doubled the number of known protein families. This is the first time protein structures have been used to help characterize the vast array of microbial “dark matter.”
Do you know your risk for breast and ovarian cancer? How about steps you can take to reduce your chances of developing cancer or what a family history might mean for your risk of the disease?
One of the world’s largest crop pathogen surveillance systems is set to expand its capacity to protect wheat productivity in food vulnerable areas of East Africa and South Asia.
Susan G. Komen® will hold a Metastatic Breast Cancer Impact Series Conference in Philadelphia that will include sessions with leading experts, survivor stories, wellness guidance, and interactive Q&A, offering attendees valuable insights, inspiration, practical tips, and community support.
Generating specific cell lineages from induced pluripotent stem cells and embryonic stem cells is the holy grail of regenerative medicine.
Immune cells play a key role during pregnancy, adjusting immune system response in a way that enables the fetus to develop while also protecting the parent and fetus from outside assaults like viruses.
The Indiana University Melvin and Bren Simon Comprehensive Cancer Center was awarded a prestigious grant to train the next generation of cancer drug discovery and development researchers. Known as a T32 grant, the five-year, $794,000 National Cancer Institute award will establish the Pediatric and Adult Translational Cancer Drug Discovery and Development Training Program (PACT-D3).
Inflammatory breast cancer is a rare type of breast cancer. It only accounts for one to five percent of all breast cancer cases, but it’s important to know your risk and the warning signs, as this form of the disease is aggressive, fast-growing, and hard to detect early. For October, during Breast Cancer Awareness Month, the American Cancer Society is highlighting IBC to help women be aware of this invasive cancer.
Fragile X syndrome, the most common form of inherited intellectual disability, may be unfolding in brain cells even before birth, despite typically going undiagnosed until age 3 or later.
By better understanding the cellular and molecular processes involved in mucus formation, scientists aim to uncover how to treat gastrointestinal-related diseases.
Plant pathogens can hitch rides on dust and remain viable, with the potential for traveling across the planet, according to a new Cornell University study – a finding with important implications for global food security and predicting future outbreaks.
The Faculty of Medicine, Chulalongkorn University, cordially invites all to attend the “Thailand Hub of Talent for Cancer Immunotherapy International Conference: Portal to Global Collaboration for Next Generation Cell and Gene Therapy Development” on November 16-17, 2023 at Bhumisiri Mangklanusorn Building, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Researchers at the UCLA Jonsson Comprehensive Cancer Center have identified a new role for a protein called extracellular signal-regulated kinase (ERK) in a pathway activated by interferon-gamma that can trigger cells to self-destruct.
Mercy's breast health experts Dr. Deepa Masrani and Dr. Wen C. Liang are guests for the October 2023 edition of "Medoscopy"; October is National Breast Cancer Awareness Month.