Feature Channels: Infectious Diseases

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The COVID-19 pandemic spotlighted how a rapid and effective response to infectious disease outbreaks is critical for saving lives and protecting communities. With a $17.5 million, five-year grant from the U.S. Centers for Disease Control and Prevention (CDC), University of Utah researchers, in collaboration with Washington State University, are leading efforts to provide data and tools that guide decisions to improve responses to emerging public health threats in the Mountain West.

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Researchers from the University of Pittsburgh and the National Institutes of Health (NIH) Vaccine Research Center have developed an improved way to test potential vaccines against bird flu. The report was published this week in the journal iScience.

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The organisms that cause visceral leishmaniasis, a potentially deadly version of the parasitic disease that most often affects the skin, appear to have a secret weapon, new research suggests: They can infect non-immune cells and persist in those uncommon environments.

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The Association for Molecular Pathology (AMP) has announced the recipients of this year’s Award for Excellence in Molecular Diagnostics, Jeffrey A. Kant Leadership Award and Meritorious Service Award.

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New Cleveland Clinic-led research shows commonly used COVID-19 anti-viral drugs Paxlovid (nirmatrelvir) and Lagevrio (molnupiravir) reduce risk of hospitalization and death in high-risk patients with mild disease, even with Omicron subvariants.

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Tuberculosis is old—ancient even. The infectious bacterial disease that plagued Old Testament Israelites and took down pharaohs was eventually stunted by vaccinations, antibiotics, and public health measures like isolation, but it hasn’t been cured yet. More than a million people around the world still die from TB every year.

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Below are some of the latest headlines in the Women's Health channel on Newswise.

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Dario C. Altieri, M.D., Wistar president and CEO, will be honored by the Justinian Foundation and Society of Philadelphia for exemplifying the finest qualities of scholarship, civic leadership and integrity.

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Michael F. Murray, MD, Professor of Medicine at the Icahn School of Medicine at Mount Sinai, has been named the new System Chief of the Division of Genomic Medicine and the Clinical Director of the Institute for Genomic Health at Mount Sinai.

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The Association for Molecular Pathology (AMP) has published a review of the current benefits and challenges to using multiplex PCR panels for the detection of microbial pathogens from gastrointestinal, central nervous system, lower respiratory tract, and joint specimens.

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New research used engineered mice to compare SARS-COV-2 omicron subvariants and found one of them – BA.5 – was more virulent likely due to its ability to rapidly replicate early during infection.

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A team led by researchers at Johns Hopkins Bloomberg School of Public Health and the National Cancer Institute has developed a new algorithm for genetic risk-scoring for major diseases across diverse ancestry populations that holds promise for reducing health care disparities.

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Research conducted at Mount Sinai and Yale confirms long COVID is a biological disease by showing blood biomarkers that can predict who has it

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Texas Biomedical Research Institute has created a new global center to foster collaborations in infectious disease research. The International Center for the Advancement of Research & Education (I·CARE) leverages the power of global exchange to solve complex health issues in an increasingly connected world.

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University of Delaware researchers conducted exhaustive studies of human papillomavirus (HPV), the most common sexually transmitted infection (STI) in the world. They confirmed 25 different types of HPV prevalent in Nigeria, a discovery that underscores the need for more region-specific vaccines.

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Researchers in Tufts University’s Lyme Disease Initiative recently received grants totaling more than $7 million to build on an already impressive array of discoveries that Tufts’ teams have made to combat tick-borne diseases.

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Natural flood disasters were associated with increased new cases and deaths of enteric infections, neglected tropical diseases, and respiratory infections. Concerted efforts should be made to design better strategies for adaptation to prevent and control the outbreak of floods-related infectious disease and reduce their impact on health and life.

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The Johns Hopkins Center for Health Security has received a five-year $23.5 million award from the Centers for Disease Control and Prevention’s Center for Forecasting and Outbreak Analytics to conduct an epidemic preparedness project as part of the CDC’s multisite Outbreak Analytics and Disease Modeling Network.

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Surprising findings from a study in Nature Medicine suggest that the burden of C. diff infection may be less a matter of hospital transmission and more a result of characteristics associated with the patients themselves.

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Russian scientists have developed an anti-bacterial gel based on silver and sulfur-containing amino acids. It is a hundred times more effective than other silver-based counterparts that also fights bacteria causing nosocomial infections.

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The study identified a molecule that reduced the spread of the herpes simplex virus in human cells.

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Researchers with the Department of Energy’s SLAC National Accelerator Laboratory and other institutions have been awarded $12 million in funding to help accelerate society’s response to emerging pathogens by improving X-ray science technology and processes.

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In response to the COVID-19 pandemic, research on coronaviruses and other harmful pathogens has increased in laboratories across the world – and not just any labs.

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Among African American and other Black cisgender women, a beauty salon–based intervention improved knowledge and awareness of pre-exposure prophylaxis (PrEP) against HIV and increased trust in it.

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Recibir la vacuna contra la COVID-19 podría significar no solo un menor riesgo de tener síndrome crónico de COVID, sino también la presencia de menos síntomas para quienes contraigan la afección.

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Researchers have determined how Leishmaniasis vaccine candidates, created using mutated disease-causing parasites, prompt molecular-level changes in host cells that have specific roles in helping generate the immune response.

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A DNA-based vaccine is very effective at protecting against COVID-19, according to a joint preclinical study by Scancell Ltd and Texas Biomedical Research Institute (Texas Biomed) recently published in the Journal of Biotechnology and Biomedicine.

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White-tailed deer across Ohio have been infected with the virus that causes COVID-19, new research has found – and the results also show that viral variants evolve about three times faster in deer than in humans.

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SCALE-UP Counts was designed to promote COVID-19 testing in local schools. Huntsman Cancer Insitute’s Yelena Wu, PhD, hopes the insight gained from the program improves cancer screening and education initiatives.

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Voluntary collective isolation alone was ineffective to mitigate the spread of COVID-19 into small-scale, remote Indigenous communities of the Tsimané in the Bolivian Amazon.

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Keck Medicine of USC experts discuss new recommendations for staying healthy and safe during the respiratory virus season

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Acute lung injury occurs when our lung’s immune system response becomes hyperactivated and causes inflammation to continue unchecked. In fact, many deaths from COVID-19 were from acute lung injury.

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Millions of Americans were exposed to SARS-CoV-2, the virus that causes COVID-19, early in the pandemic but could not get diagnosed due to testing limitations. Many of those people developed a post-viral syndrome with symptoms similar to those of long COVID.

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Getting a COVID-19 vaccine may not only reduce a person's risk of getting long-haul COVID, but also could mean fewer symptoms for people who develop the condition.