Feature Channels: Men's Health

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Staphylococcus aureus, Clostridioides difficile, Candida auris, Drug-resistant Shigella. These bacteria not only have difficult names to pronounce, but they are also difficult to fight off. These bacteria may infect humans and animals, and the infections they cause are harder to treat than those caused by non-resistant bacteria. Antimicrobial resistance is an urgent global public health threat.

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Depression is widely reported to be more common in women than in men, with women twice as likely to receive a diagnosis than men.

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Researchers may have found why viral infections hit males more severely than females. They found that female mouse and human NK cells have an extra copy of an X chromosome-linked gene called UTX. UTX acts as an epigenetic regulator to boost NK cell anti-viral function, while repressing NK cell numbers.

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The combination of two oral medications has shown positive results in people with prostate cancer, whose disease has spread to other parts of the body. Compared with XTANDI plus placebo, the investigatory combination of TALZENNA and XTANDI demonstrated a statistically significant and clinically meaningful improvement in radiographic progression-free survival.

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It's sleep awareness week, according to the National Sleep Foundation. It’s important to understand how sleep deprivation can impact your health. Most people recognize that if they don’t get enough sleep, their mood and memory will suffer the next day.

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Shivank Bhatia, M.D., chair of Interventional Radiology at the University of Miami Miller School of Medicine, made headlines at the recent Society of Interventional Radiology (SIR) Annual Scientific Meeting when he presented results of the largest long-term North American study of men undergoing prostate artery embolization to treat urinary symptoms from an enlarged prostate.

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Nima Sharifi, M.D., has been named scientific director of the University of Miami Miller School of Medicine’s Desai Sethi Urology Institute, a role in which he will collaborate with Sylvester Comprehensive Cancer Center to drive translational science focused on prostate and other genitourinary cancers.

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A new computational study in a mouse model finds biological sex and time of day makes a difference in the effectiveness of diuretics—medications commonly prescribed to manage high blood pressure. The study is published ahead of print in the American Journal of Physiology-Renal Physiology.

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A first-of-its-kind study in the March 2023 issue of JNCCN highlights how the lack of genomic research for people with African ancestry, particularly those from the Sub-Saharan region, is hampering efforts to reduce disparities for people with advanced prostate cancer.

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At this year’s American Academy of Orthopaedic Surgeons (AAOS) Annual Meeting, held March 7 to 11 in Las Vegas, Hospital for Special Surgery (HSS) presented new research on a variety of topics in orthopedic surgery, including studies related to minimally invasive surgery, racial disparities, and opioid alternatives for pain management in spine care.

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New research from the University of South Australia shows that men who stick to a predominantly Mediterranean diet are less likely to be diagnosed with prostate cancer. This diet also improves their chances of recovery if they have prostate cancer and are undergoing radiation treatment.

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Read how researchers discovered genetic markers that hinder pancreatic cancer treatment and mutations that increase sarcoma risk. Then learn how artificial intelligence is helping predict prostate cancer outcomes and see how a new clinical trial looks at less-invasive breast cancer treatments. Finally, find out how a new grant could help veterans get the cancer care they need.

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The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.

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Because females 65 and older have an increased rate of falls and facial fractures, researchers compared the risk of skull fracture secondary to head trauma in geriatric female and male patients. Results showed that males had a significantly increased incidence of skull fracture secondary to head trauma, due mostly to falls. This outcome was unexpected, as previous research has indicated females are more susceptible to facial fractures. This trend also was seen across race/ethnicity, though results were only statistically significant for whites.

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With the goal of improving cervical cancer care, AACC has published a new guidance document with expert recommendations on detecting this cancer. The guidance aims to update healthcare and laboratory medicine professionals on the latest advancements in this field, and to help them select the most effective cervical cancer detection strategy for their patients.

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A combination treatment that targets the immune system helps treat aggressive prostate cancers that don’t respond to conventional therapies.

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Older Black men have a higher chance of dying within 30 days of surgery than do Black women and white men and women – with their odds of death 50% higher after elective surgery compared with white men.

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A new mathematical model which aims to optimise treatment for prostate cancer has been developed by experts at the University of Portsmouth.

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Dana-Farber is leading two studies to investigate novel treatment options for colorectal cancer patients. One study is looking at next-generation immunotherapy and the other is investigating CAR-T therapy in colorectal cancer.

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Learn about the latest research breakthroughs and faculty updates at Cedars-Sinai for February 2023.

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The UNM Cancer Center will be one of a few sites in the country participating in a clinical trial to expand the application of theranostic treatment to patients with prostate cancer. This type of treatment is currently used at the cancer center for neuroendocrine tumors. The treatment is a two-part process that first injects the molecule attached to a gallium-68 radioactive isotope that can be imaged to illuminate the cancer cells, which makes them easier to see under Positron Emission Tomography, or PET scans.

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Emad Ibrahim, M.D., director of the Male Fertility Research Program at The Miami Project to Cure Paralysis and the clinical andrology lab at the Desai Sethi Urology Institute at the University of Miami Miller School of Medicine, has been awarded a $3.25 million grant by the Department of Defense for a four-year study on the use of an oral medication to treat an infertility issue that affects most men with spinal cord injury.

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Half of all men aged 50 have an enlarged prostate. Learn about the symptoms and treatments for this common condition.

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A Yale-led study examines the potential environmental benefits of more carefully selecting patients for prostate biopsy in a way that can also spare low-yield and potentially harmful procedures

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Below are some of the latest articles that have been added to the Chemistry news channel on Newswise.

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Eating disorders are behavioral conditions in which normal eating habits become disrupted and rewarded in an unhealthy way. They can affect a person’s physical and mental health, and often happen in combination with other psychiatric conditions such as depression, anxiety or substance use disorder.

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For men undergoing surgery to repair scarring in the urethra (urethroplasty), a new approach to pain management can reduce the need for strong opioid drugs without compromising pain control, reports a study in Urology Practice®, an Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer.

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Declines in prostate-specific antigen (PSA) level after treatment with the next-generation androgen receptor inhibitor drug enzalutamide predict improved survival rates in men with non-metastatic castration-resistant prostate cancer (nmCRPC), reports The Journal of Urology®, an Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer.

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In a large-scale nationwide study, investigators from Cedars-Sinai Cancer have confirmed that rates of pancreatic cancer are rising—and are rising faster among younger women, particularly Black women, than among men of the same age. Their work was published today in the peer-reviewed journal Gastroenterology.

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A new drug company founded by entrepreneur Mark Cuban could save patients $1.29 billion a year based on 2020 Medicare Part D expenditures on just the nine most popular urological drugs, according to a study published in the Journal of Urology.

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The human body runs on a finely tuned clock synchronized to the 24-hour cycle of Earth’s rotation, known as the circadian clock, which controls various physiological processes such as the sleep-wake cycle, hormone production, and metabolism.

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For the first time, researchers have discovered that prostate cancer can be killed by targeting a single enzyme. The findings could help address the growing threat of prostate cancer resistance and could also lead to improved treatments for other cancers.

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Cedars-Sinai Cancer investigators have developed a new nanotechnology-based test that can detect and profile prostate cancers—even in microscopic amounts.

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Below are some of the latest articles that have been added to the Surgery and the Transplantation channels on Newswise, a free source for journalists.

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A new survey finds that men who would be potential users of HIV pre-exposure prophylaxis (PrEP) medication prefer long-acting injections over pills, but rank side effects and costs as the most important issues for them in considering whether to take PrEP.

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Predominant stereotypes about eating disorders suggest that it is a condition mainly associated with girls from wealthy backgrounds. However, a new study from Michigan State University found that boys living in disadvantaged circumstances are at an increased risk for disordered eating, particularly if they have underlying genetic risk factors.

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“The availability of the PYLARIFY test at JFK University Medical Center means patients with prostate cancer no longer need to travel to obtain PSMA-targeted PET imaging. They can get this innovative technology close to home,” said Amie Thornton, president, chief hospital executive, JFK University Medical Center.

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From urologic cancers to female urology to male infertility to kidney stones and sexual health, top urologists from throughout the nation shared their insights and practical tips at “Urology on the Beach,” a conference hosted January 13-15 by the Desai Sethi Urology Institute at the University of Miami Miller School of Medicine.

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Fertilization is the union of two cells: an egg and a sperm. Before the egg and the sperm fuse, an event known as the “acrosome reaction” needs to occur in the sperm.