Feature Channels: Autoimmune Diseases

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Released: 11-Feb-2021 5:15 PM EST
ACR COVID-19 Vaccine Guidance Recommends Vaccination, Addresses Immunosuppressant Drugs & Patient Concerns
American College of Rheumatology (ACR)

The American College of Rheumatology (ACR) has released its COVID-19 Vaccine Clinical Guidance Summary that provides an official recommendation to vaccinate rheumatology patients with musculoskeletal, inflammatory and autoimmune diseases. Important considerations and caveats on how to approach vaccination are included for patients with high disease activity and/or those taking immunosuppressant treatments.

Released: 2-Feb-2021 7:00 AM EST
Surgery to Heal Inflamed Gut May Create New Target for Disease
NYU Langone Health

A surgical procedure meant to counter ulcerative colitis, an immune disease affecting the colon, may trigger a second immune system attack, a new study shows.

Released: 28-Jan-2021 1:10 PM EST
Scientists Find Key Function of Molecule in Cells Crucial for Regulating Immunity
University of North Carolina School of Medicine

Scientists discovered that the molecule AIM2 is important for the proper function of regulatory T cells and plays a key role in mitigating autoimmune disease. Treg cells are a seminal population of adaptive immune cells that prevents an overzealous immune responses.

Released: 22-Jan-2021 10:20 AM EST
Cross-Country Research Collaboration Brings First Ever Lupus Estimates
Michigan Medicine - University of Michigan

A meta-analysis of lupus finds the disease is less common than previously thought, but disproportionally affects women and racial and ethnic minorities of both sexes.

18-Jan-2021 9:00 AM EST
Study Pins Down Number of Americans with Most Common Form of Lupus
NYU Langone Health

Just over 200,000 Americans suffer from systemic lupus erythematosus, or SLE, a condition in which the body's immune system mistakenly attacks its own healthy tissues, especially joints and skin, a new study shows.

Released: 19-Jan-2021 11:35 AM EST
National Research Effort Discovers Relationship Between Inflammation, Metabolism and Scleroderma Scarring
Michigan Medicine - University of Michigan

Study finds NAD+ break down leads to multi organ scarring, providing now a previously undiscovered pathogenic role of the enzyme CD38 in disease scarring.

Released: 13-Jan-2021 12:30 PM EST
AARDA Announces Leadership Transition
Autoimmune Association

The American Autoimmune Related Diseases Association announced that Randall Rutta, President and CEO, is leaving to join the National Health Council (NHC) as its CEO, effective February 12, 2021.

Released: 6-Jan-2021 11:05 AM EST
New Research Finds Ginger Counters Certain Autoimmune Diseases in Mice
Michigan Medicine - University of Michigan

The main bioactive compound of ginger root lowers autoantibody production and helps halt disease progression in mice with antiphospholipid syndrome and lupus.

Released: 17-Dec-2020 3:15 PM EST
Protein Linked to Progressive Lung Scarring in Scleroderma Patients
Michigan Medicine - University of Michigan

Osteopontin is discovered as the culprit behind these patients’ main cause of death. However, a repurposed immunosuppressive drug may combat the pro-inflammatory protein.

2-Dec-2020 9:50 AM EST
Targeting T cell protein could prevent type 1 diabetes, study suggests
The Rockefeller University Press

Researchers at the University of Utah School of Medicine have identified a new therapeutic target to treat patients with type 1 diabetes. The study, which will be published December 9 in the Journal of Experimental Medicine (JEM), reveals that inhibiting a protein called OCA-B protects mice from type 1 diabetes by limiting the activity of immune cells that would otherwise destroy the pancreas’ insulin-producing β cells.

Released: 17-Nov-2020 9:55 AM EST
Study explores sleep apnea, autoimmune disease link
University of Georgia

New research by University of Georgia scientists sheds light on why people with obstructive sleep apnea may have associated autoimmune disorders. The results could lead to better approaches to treatment and possibly new drug therapies.

8-Nov-2020 9:00 AM EST
Improving the Diagnosis of Chronic Nonbacterial Osteomyelitis, an Underdiagnosed Chronic Autoinflammatory Syndrome
Hospital for Special Surgery

Researchers have identified several factors that should help improve the diagnosis of chronic nonbacterial osteomyelitis (CNO), also known as chronic recurrent multifocal osteomyelitis (CRMO). The new study was presented at the virtual annual meeting of the American College of Rheumatology.

Released: 6-Nov-2020 9:00 AM EST
With Close Monitoring Throughout, Safe Pregnancy is Possible for Women with Interstitial Lung Disease
American College of Rheumatology (ACR)

A new study shows that women with interstitial lung disease (ILD) related to autoimmune disease may not need to terminate their pregnancies provided they have close monitoring from their team of multidisciplinary physicians before, during and after pregnancy. Results of the research was presented at ACR Convergence, the American College of Rheumatology’s annual meeting.

Released: 6-Nov-2020 9:00 AM EST
Many with Lupus at High Risk for Adverse Reactions to Pneumocystis Pneumonia Preventive Drug
American College of Rheumatology (ACR)

New research shows that adults with systemic lupus erythematosus, who receive trimethoprim-sulfamethoxazole (TMP-SMX) are at high risk for adverse reactions to the drug, particularly if they are also positive for anti-Smith (anti-Sm) antibodies. Details of the study was presented at ACR Convergence, the American College of Rheumatology’s annual meeting.

Released: 6-Nov-2020 9:00 AM EST
Hydroxychloroquine Not Linked to Longer Heart Rhythm Intervals in Rheumatoid Arthritis or Lupus Patients
American College of Rheumatology (ACR)

New research presented at ACR Convergence, the American College of Rheumatology’s annual meeting, discovers that use of hydroxychloroquine does not cause any significant differences in QTc length or prolonged QTc in people with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE).

2-Nov-2020 12:25 PM EST
A Novel Immunotherapy Proves Effective in Animal Models of Multiple Sclerosis
Thomas Jefferson University

Jefferson researchers develop an approach to specifically impede the autoimmune response that drives the disease, while leaving the rest of the immune system fully functioning.

   
21-Oct-2020 3:35 PM EDT
New Population of Immune Cells Could Play a Role in Multiple Sclerosis
Thomas Jefferson University

Researchers uncover defining features of a subset of T-cells that may drive autoimmunity in MS, and could prove to be a new target for therapy.

Released: 24-Sep-2020 4:30 PM EDT
Physicians issue warning about rare neurological condition, expected to appear this fall
University of Chicago Medical Center

Pediatricians Henry David, MD, and Madan Kumar, DO, of the University of Chicago Medicine Comer Children's Hospital warn parents of young children to watch out for symptoms of acute flaccid myelitis (AFM), a rare neurological disorder linked to viral infections that can lead to permanent paralysis.

Released: 22-Sep-2020 8:00 AM EDT
MEDIA ALERT: MSVirtual2020
Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS)

The MSVirtual2020 program will continue in an Encore Program that will be held on Saturday, September 26th from 9:00 a.m. – 12:15 p.m. ET. This Encore Program will feature the Late Breaker (9-10:30 a.m. ET) and COVID-19th (10:45 a.m. – 12:15 p.m. ET) sessions.

Released: 21-Sep-2020 1:50 PM EDT
Regulatory T cells could lead to new immunotherapies aimed at treating multiple sclerosis
University of California, Irvine

In a new University of California, Irvine-led study, researchers have discovered how regulatory T cells (Treg) are instrumental in limiting the damage caused to the spinal cord in diseases like multiple sclerosis (MS).

Released: 21-Sep-2020 10:20 AM EDT
American College of Rheumatology Secures $7M Grant to Address Gaps in Lupus Care and Treatment
American College of Rheumatology (ACR)

The American College of Rheumatology (ACR) was recently awarded a $7M grant to reduce inequities in symptom recognition, care and disease management of systemic lupus erythematosus (lupus). The grant, which will be led by the ACR’s Collaborative Initiatives (COIN) department, begins on Sept. 30.

Released: 17-Sep-2020 8:05 AM EDT
Children Who Take Prescription Steroids at Increased Risk for Diabetes, High Blood Pressure, Blood Clots
Rutgers University-New Brunswick

Children who take oral steroids to treat asthma or autoimmune diseases have an increased risk of diabetes, high blood pressure, and blood clots, according to Rutgers researchers.

Released: 11-Sep-2020 6:15 PM EDT
Welcome Letter from ACTRIMS President on MSVirtual2020
Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS)

It is with great pleasure that I welcome you to the 8th joint ACTRIMS-ECTRIMS conference. This conference, MSVirtual2020, is the largest conference dedicated to multiple sclerosis (MS) research and our first virtual conference.

Released: 9-Sep-2020 3:20 PM EDT
Pro-inflammatory lipids precede Type 1 diabetes onset in mouse model and children
University of Alabama at Birmingham

Inflammatory lipid signaling may provoke the autoimmune disease Type 1 diabetes. Researchers have identified a proinflammatory lipid profile that precedes development of T1D in a mouse model and in children under age 15 who are at high risk for T1D. These lipids may be therapeutic targets.

23-Aug-2020 9:00 PM EDT
Blocking nerve signals to the pancreas halts type 1 diabetes onset in mice
La Jolla Institute for Immunology

Blocking nerve signals to the pancreas could stop patients from ever developing type 1 diabetes.

   
Released: 25-Aug-2020 9:00 AM EDT
Most Adults with Lupus or Common Types of Arthritis Have Similar Risks of Getting Admitted to Hospital as Other COVID-19 Patients
NYU Langone Health

Most adults with systemic lupus erythematosus (SLE) are not at increased risk of hospitalization from COVID-19 due to medications used to dampen their altered immune system, the cause of their disease. Nor are most people with more common types of arthritis, such as rheumatoid, psoriatic and spondyloarthritis, at greater risk of hospitalization from COVID-19, a pair of new reports shows.

Released: 24-Aug-2020 3:05 PM EDT
Inflammatory Bowel Disease Linked to an Immune Cell Run Amok
UC San Diego Health

Researchers at UC San Diego School of Medicine report that the lasting nature of inflammatory bowel disease may be due to a type of long-lived immune cell that can provoke persistent, damaging inflammation in the intestinal tract.

Released: 6-Aug-2020 3:55 PM EDT
AARDA Mourns the Loss of Dr. Noel R. Rose, "The Father of Autoimmunity"
Autoimmune Association

AARDA Tribute to Dr. Noel R. Rose, "The Father of Autoimmunity"

Released: 5-Aug-2020 1:05 PM EDT
How Climate Change Affects Allergies, Immune Response and Autism
Rutgers University-New Brunswick

The changes in the environment and biodiversity brought on by climate change could be responsible for increases in allergies, autoimmune diseases and autism, according to a Rutgers researcher

Released: 4-Aug-2020 3:05 PM EDT
Study: Enzyme Could Prove Effective in Treating Tumors and Inflammatory Diseases in Lung
Henry Ford Health

Findings from a research study, led by scientists at Henry Ford, suggest an enzyme could play an important role in the treatment of cancer and autoimmune diseases in the airway.

Released: 3-Aug-2020 2:30 PM EDT
In Memoriam: Noel R. Rose, 1927-2020
Johns Hopkins Bloomberg School of Public Health

Noel R. Rose, MD, PhD, a longtime Johns Hopkins Bloomberg School of Public Health faculty member and researcher recognized as a father of autoimmune disease research, died Thursday. Rose, 92, died at home in Brookline, Massachusetts.

24-Jul-2020 5:05 PM EDT
Novel label-free imaging technique brings out the inner light within T cells
Morgridge Institute for Research

A new imaging method developed by the Skala lab uses the natural autofluorescence within cells to assess T cell activity. The technique could help assess T cell involvement in immunotherapies.

   
Released: 23-Jul-2020 11:00 AM EDT
Dual role discovered for molecule involved in autoimmune eye disease
NIH, National Eye Institute (NEI)

The inflammatory molecule interleukin-17A (IL-17A) triggers immune cells that in turn reduce IL-17A’s pro-inflammatory activity, according to a study by National Eye Institute (NEI) researchers.

15-Jul-2020 4:25 PM EDT
Immune system adaptations in cavefish may provide autoimmune disease insight
Stowers Institute for Medical Research

Cavefish may not seem like a big deal. They’re small, they live in tucked away places humans rarely go, and they’re common enough that you can find them on every continent except Antarctica. But researchers from the Stowers Institute for Medical Research see them as a potential way to understand more about the rise in autoimmune diseases in humans.

Released: 8-Jul-2020 2:55 PM EDT
CHOP-Pioneered Spatial Mapping Method Pinpoints Potential New Therapeutic Targets in Lupus
Children's Hospital of Philadelphia

A team of researchers from Children’s Hospital of Philadelphia (CHOP) used a new method of pinpointing potential disease-causing changes in the genome to identify two new potential therapeutic targets for lupus, while also paving the way for more accurately identifying disease-causing variations in other autoimmune disorders.

Released: 30-Jun-2020 8:00 AM EDT
8th Joint ACTRIMS-ECTRIMS (MSVirtual2020) Meeting to Be Held Virtually September 11-13, 2020 with an Encore Event on September 26th with Late Breakers and Special Session on COVID-19
Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS)

Registered media to MSVirtual2020 will have access to the full program including plenary sessions, invited speakers and platform presentations of abstracts, poster presentations, teaching courses, and industry supported satellite symposia, both scheduled and on-demand

Released: 29-Jun-2020 11:30 AM EDT
Letter from ACTRIMS President on MSVirtual2020
Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS)

I am pleased to announce that the 8th Joint ACTRIMS-ECTRIMS Meeting will be held from September 11-13, 2020, with a special encore featuring Late-Breaking News and a COVID-19 Session on September 26.

17-Jun-2020 4:35 PM EDT
LJI Scientists Investigate a Powerful Protein Behind Antibody Development
La Jolla Institute for Immunology

Scientists at the La Jolla Institute for Immunology (LJI) have discovered a potential new way to better fight a range of infectious diseases, cancers and even autoimmune diseases. The new study, published recently in Nature Immunology, shows how a protein works as a “master regulator” in the immune system.

Released: 19-Jun-2020 9:00 AM EDT
Prominent Rheumatologist to Create Scleroderma Program at Kao Institute
Cedars-Sinai

Nationally recognized rheumatology expert Francesco Boin, MD, has been appointed director of the division of Rheumatology and director of the new Scleroderma Program at Cedars-Sinai. Boin is an accomplished and widely published investigator of autoimmune diseases, with a reputation for clinical excellence and a multidisciplinary approach to patient care.



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