Focus: Hidden - Colorado

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Study of 11,626 people shows that, all else equal, smokers are 60 percent less likely to vote than nonsmokers.

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U.S. residents' exposure to extreme heat could increase four- to six-fold by mid-century, due to both a warming climate and a population that's growing especially fast in the hottest regions of the country, according to new research by NCAR scientists.

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New research led by NCAR and CDC has identified correlations between weather conditions and the occurrence of West Nile virus disease in the United States, raising the possibility of being able to better predict outbreaks.

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How a cardiac ablation procedure ultimately saved the life of Gus, a young boxer dog

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Analagous to the NCI-60, a new panel of authenticated K9 cancer cell lines presented at AACR 2015 lets veterinary researchers experiment with known cells.

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While dietary supplements may be advertised to promote health, a forum at the American Association for Cancer Research (AACR) Annual Meeting 2015 by University of Colorado Cancer Center investigator Tim Byers, MD, MPH, describes research showing that over-the-counter supplements may actually increase cancer risk if taken in excess of the recommended dietary amount.

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The ACVIM Foundation and Zoetis have announced a renewal of Zoetis' support for clinical training of ACVIM residents.

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Measuring blood pressure of our cats and dogs can be a challenge, says Dr. Anthony Carr, of Saskatoon, Saskatchewan, Canada, who will be addressing the American College of Veterinary Internal Medicine Forum in Indianapolis, Ind., June 3.

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"It's very simple: tumors from mice that were initially fed silibinin had fewer cancer stem cells, were smaller, had lower metabolisms and showed decreased growth of new blood vessels," says University of Colorado Cancer Center researcher.

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At AACR, joint study by NCI and University of Colorado Cancer Center shows TERT is most commonly mutated gene in bladder cancer.

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In a major symposium at the American Association for Cancer Research (AACR) Annual Meeting 2015, University of Colorado Cancer Center investigator Tim Byers, MD, MPH, examines research demonstrating the link between cancer, diabetes and cardiovascular disease.

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Results presented at AACR 2015 show oncogene recognized in NSCLC in small cell lung cancer, as well, implying that medicines in development for the first may be applicable to second.

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New work by the University of Colorado Cancer Center presented at AACR 2015 demonstrates a gene expression model that predicts canine osteosarcoma response to doxorubicin, potentially allowing veterinary oncologists to better choose which drug to use with their patients.

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"Tanning beds cause skin cancer. It is time to now more openly announce this causality," says Robert P. Dellavalle, MD, PhD, MSPH, investigator at the CU Cancer Center, in the American Journal of Preventive Medicine.

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A University of Colorado Cancer Center study published today in the journal Nature Genetics describes a newly-discovered, heritable genetic cause of acute lymphoblastic leukemia (ALL), namely mutation of the gene ETV6.

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University of Colorado Cancer Center study shows that of prostate cancer patients with combination MAP3K7 and CHD1 deletions, about 50 percent will have recurrent prostate cancer, which ultimately leads to death. About 10 percent of all prostate cancers harbor combined MAP3K7-CHD1 deletions.

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The American Academy of Physiological Medicine & Dentistry (AAPMD) “Silent Airway Connection” Conference, held March 27-29 in New York City, to focus on multidisciplinary approach for diagnosing and treating pediatric and adult breathing and sleep disorders

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A University of Colorado Cancer Center study published in the journal Pediatric Blood & Cancer shows that pediatric cancer patients who receive antibiotics within 60 minutes of reporting fever and showing neutropenia (low neutrophil count), go on to have decreased intensive care needs and lower mortality compared with patients who receive antibiotics outside the 60-minute window.

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Total fruit consumption falls far short of national goals. More than 85% of the population is not meeting recommended amounts. General fruit consumption patterns show whole fruit provides about 65% (2/3’rds) of total fruit while 100% juice provides about 35% (1/3). These findings show 100% juice does not displace fruit in the diet and is not typically overconsumed – even among children (the largest consumers of juice). Consumption patterns for whole fruit versus 100% fruit juice showed different gradients by race/ethnicity, education, and income. Total fruit and whole fruit consumption was generally higher among those with higher incomes or more education. The advice to replace 100% juice with whole fruit may pose a challenge for the economically disadvantaged and some minority groups, whose fruit consumption falls short of national goals..For those segments of the population who are unable to afford whole fresh fruit, 100% fruit juice offers a convenient, affordable, and nutrient-den

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Clinical trials are underway of anti-androgen drugs against high-androgen triple-negative breast cancers, and new work from the University of Colorado Cancer Center shows the threshold for benefit from anti-androgen therapies may be much lower than previously thought: even breast cancers with few androgen receptors benefit from anti-androgen therapy.

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University of Colorado Cancer Center study published in the journal SCIENCE shows that mRNA levels for the gene TERT predict patient outcomes in bladder cancer, helping doctors and researchers pinpoint most aggressive forms of the disease and choose appropriate treatments.

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45 percent of younger patients report moderate-to-high distress, whereas only 18 percent of older patients report similarly elevated levels.

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CSU researchers led two national studies measuring methane emissions at different sectors in the natural gas supply chain. This press release outlines the measurement results from the gathering and processing sectors.

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CSU researchers led two national studies measuring methane emissions at different sectors in the natural gas supply chain. This press release outlines the measurement results from the transmission and storage sectors.

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"Identification of alterations common to adult tumors, in our case upregulation of PIK3R3 and loss of PTEN, could potentially allow us to adapt therapeutic strategies for adult cancers to treat Ewing Sarcoma," says Paul Jedlicka, MD, PhD, investigator at the University of Colorado Cancer Center.

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“Increasingly physicians are being presented with health economic analyses in mainstream medical journals as a means of potentially influencing their prescribing. However, it is only when you understand the multiple assumptions behind these calculations that you can see that they are by no means absolute truths,” says D. Ross Camidge, MD, PhD, investigator at the University of Colorado Cancer Center.

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The American College of Veterinary Internal Medicine Foundation (ACVIMF) has announced three new calls for grant proposals focusing on Small Animal Internal Medicine (SAIM) respiratory disease ($20,000) sponsored by Zoetis, general oncology ($25,000) and feline chronic renal disease ($50,000).

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A University of Colorado Cancer Center study published in the British Medical Journal: Tobacco Control shows that of the top 100 universities as ranked by U.S. News and World Report, 11 allow tobacco sales and 13 allow e-cigarette sales on “campus cash” debit cards that are commonly prepaid by parents.

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Placental cells could potentially be used to treat stroke or other injuries to the nervous system attributable to low oxygen or glucose levels according to newly published study.

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University of Colorado Cancer Center study shows that pre-programmed stem cell demise allows cancer after radiation, and that NOTCH signaling can restore stem cell function.

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New research indicates that shifts in Pacific trade winds played a key role in twentieth century climate variation and are likely again influencing global temperatures. The study, led by NCAR and the University of Arizona, uses a novel method of analyzing coral chemistry to reveal winds from a century ago.

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University of Colorado Cancer Center study published today in the journal Aging shows that in addition to DNA damage, cancer depends on the slow degradation of tissue that allows cancer cells to out-compete healthy cells.

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"We're on the cusp of a major revolution in the way we treat breast cancer," says University of Colorado Cancer Center investigator, Jennifer Richer, PhD.

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University of Colorado Cancer Center study being presented at the San Antonio Breast Cancer Symposium shows that triple negative breast cancer cells process tryptophan to promote survival while traveling through the body in order to seed new tumor sites.

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New research led by NCAR shows that an increase in greenhouse gases thousands of years ago helped cause substantially more rainfall in two major regions of Africa. The finding provides new evidence that the current increase in greenhouse gases will have an important impact on Africa’s future climate.

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"Alcohol damages cells and resveratrol kills damaged cells," says Robert Sclafani, PhD.

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Experimental anti-cancer drugs PF-04691502 and PD-0325901 excel in tests against colorectal cancer models and enter phase 1 clinical trial.

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University of Colorado Cancer Center study shows "extremely promising” early phase 1 clinical trial results for the investigational drug AG-120 against the subset of patients with acute myeloid leukemia (AML) harboring mutations in the gene IDH.

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The American College of Veterinary Internal Medicine Foundation (ACVIMF), is partnering with the Veterinary Pharmacology Research Foundation (VPRF), to fund a new study for animal health with a pharmacologic focus. The study will be conducted by Dr. Lauren Trepanier of the University of Wisconsin-Madison for the genetic risk for cyclophosphamide toxicity in dogs.

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A University of Colorado Cancer Center study published online this week in the journal Molecular Cancer Therapeutics reports anti-cancer activity in 10 out of 11 patient tumor samples grown in mice and treated with the experimental drug TAK-733, a small molecule inhibitor of MEK1/2.

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Researchers Conclude: Replacing Saturated Fat With Linoleic Acid, the Polyunsaturated Omega-6 Fat in Vegetable Oils, Lowers Risk of Coronary Heart Disease Related Events

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University of Colorado Cancer Center study shows that IL-37 regulates immune sensitivity across disease types