Credit: Tien-Phat Huynh
Clumps of a damaging Alzheimer’s protein (white spots) are scarcer in the brains of mice treated with a DNA-based compound (top) as compared with those given a placebo (bottom). The compound targets APOE4, a genetic variant that magnifies a person’s risk of the disease. The findings suggest that targeting APOE could potentially prevent or delay onset of Alzheimer’s.