Released: 8-Feb-2006 3:00 PM EST
Texas, Brazilian Scientists Collaborate on Novel TB Vaccine
Texas Biomedical Research Institute

Southwest Foundation for Biomedical Research in San Antonio is collaborating with Brazilian scientists to conduct further tests on a promising candidate vaccine for tuberculosis. Previous tests have demonstrated the vaccine's potential as both a preventive and therapeutic.

Released: 10-Feb-2006 4:00 PM EST
Scientists Unveil Genetic Linkage Map for Rhesus Macaque
Texas Biomedical Research Institute

The quest to find genes that influence disease should be much more productive now that scientists at Southwest Foundation for Biomedical Research have published a genetic linkage map for the rhesus macaque monkey, the most commonly used nonhuman primate in biomedical research.

Released: 22-Mar-2006 1:00 PM EST
Can Texas Plants Help Fight Cancer?
Texas Biomedical Research Institute

Researcher is looking for new anti-cancer compounds in plants, and is focusing on plants that thrive in Texas, where she is based. She believes that the same chemical properties that give Texas plants their hardiness might also be useful in fighting cancer.

Released: 25-Sep-2006 2:25 PM EDT
Could an Infection Break Your Heart?
Texas Biomedical Research Institute

A new study at Southwest Foundation for Biomedical Research is looking for genetic factors that increase our susceptibility to some of this country's most common chronic infections, and ultimately, how that susceptibility might be linked to our risk for cardiovascular disease.

Released: 10-Jan-2007 11:00 AM EST
Cure for Most Heart Attacks Is Free, but It's Important to Start Young
Texas Biomedical Research Institute

Scientists say the risk factors for adult heart disease are already impacting children, starting to clog their arteries as early as age 12 and setting them up for future health problems. The good news is, the fix is free. For zero cost and a high pay-off, we need to teach children to lead healthy lifestyles.

Released: 4-Jan-2007 6:00 AM EST
Researchers Looking for Genes That Control the Brain
Texas Biomedical Research Institute

The largest study of its kind combines powerful resources to explain normal brain biology and shed light on the root causes of mental illness.

9-Apr-2007 2:10 PM EDT
DNA Sequence Unleashes Potential of Rhesus Genome
Texas Biomedical Research Institute

The most widely used nonhuman primate in biomedical research is even more valuable since the complete DNA sequence of the rhesus genome has been announced. San Antonio scientists who assisted with the effort and who led the nomination of the rhesus for full genome sequencing say the development has tremendous potential to advance a broad range of studies on human health.

7-May-2007 7:30 PM EDT
Marsupial Genome Sequence to Advance Human Health Studies
Texas Biomedical Research Institute

The genome sequencing of the laboratory opossum, reported in Nature on May 10, should advance biomedical research on heart disease, skin cancer, spinal cord injury, fetal development and other biomedical research topics, says the scientist who first developed this animal research model.

Released: 30-May-2007 6:00 AM EDT
New Animal Model Boosts Biodefense Research on Lassa Fever
Texas Biomedical Research Institute

In the current edition of the Journal of Virology, scientists from Southwest Foundation for Biomedical Research report on the development of the common marmoset monkey as a new animal model to advance biodefense research against a potential biological weapon, Lassa fever. Endemic to West Africa, the virus kills thousands of people each year.

Released: 13-Aug-2007 9:00 AM EDT
Gift to Technology Boosts Power for Gene Discovery
Texas Biomedical Research Institute

Gifts to technology at Southwest Foundation for Biomedical Research are ramping up already world-renowned genetic research resources, dramatically accelerating the speed with which scientists can hunt for genes that influence complex human diseases as varied as heart disease, diabetes, brain disorders and cancer.

Released: 27-Aug-2007 9:00 AM EDT
Unique Mouse Joins Battle Against Dengue Fever
Texas Biomedical Research Institute

A unique mouse provides the first animal model for dengue fever, enabling tests of antiviral therapies. Now the model is being further developed so it can be used to test vaccines against this mosquito-borne disease.

Released: 10-Sep-2007 8:40 AM EDT
Study Sheds Light on Role of Vitamin E in Heart Disease Prevention
Texas Biomedical Research Institute

Should you increase your vitamin E intake to prevent heart disease? The answer is "maybe." Research by scientists at Southwest Foundation for Biomedical Research helps explain why human studies have been contradictory, and why vitamin E might help some but not others.

12-Sep-2007 9:00 AM EDT
New Method Speeds Up Gene Discovery, Pinpoints Cholesterol Gene
Texas Biomedical Research Institute

Scientists will be able to pinpoint genetic causes of human diseases faster than ever with a powerful new discovery method unveiled in the Sept. 16 online edition of Nature Genetics. An international team led by Southwest Foundation for Biomedical Research explains the new method and how it was used to find a gene that regulates HDL, the good cholesterol.

Released: 24-Sep-2007 4:00 PM EDT
Department of Homeland Security Funds $1.5 Million Research Contract
Texas Biomedical Research Institute

As an important part of the federal government's efforts to better characterize the threat posed by certain viruses, the Department of Homeland Security (DHS) has awarded a $1.5 million contract to fund one of the most comprehensive research programs to date on Marburg virus, a hemorrhagic fever virus.

Released: 12-Dec-2007 8:00 AM EST
Researchers Learning How Genes Influence Diabetes Risk
Texas Biomedical Research Institute

Scientists at Southwest Foundation for Biomedical Research expect to make big leaps in their understanding of genetic influences on diabetes, as they begin detailed investigations on 100 genes they've shown to influence diabetes risk factors. Uncovering how these genes work could lead to new methods of disease prevention and treatment.

Released: 12-May-2008 12:00 PM EDT
Drug Development Company Launched by SFBR to Focus on Women's Health
Texas Biomedical Research Institute

One of the Southwest Foundation for Biomedical Research's longest running departments is being spun off as a private, for-profit business enterprise based on the massive body of work the department has accumulated in female reproductive and related health issues.

Released: 30-Jul-2008 5:00 PM EDT
Southwest Foundation for Biomedical Research Names New President
Texas Biomedical Research Institute

With 26 years of senior management experience at several of the leading independent biomedical research institutes in the United States, Kenneth Trevett is eminently qualified to build on SFBR's track record of success and lead it to even greater achievements in its efforts to improve human health.

Released: 22-Sep-2008 9:00 AM EDT
SFBR Launches Groundbreaking Studies on Heart Disease
Texas Biomedical Research Institute

An $18.8 million federal research grant to Southwest Foundation for Biomedical Research will allow scientists to embark on several groundbreaking new studies on cardiovascular disease. Projects include searches for entire networks of genes that influence disease risk; studies on the response of endothelial cells to various risk factors; and investigations on ways to boost the body's production of stem cells that could help prevent atherosclerosis and treat heart attack victims.

Released: 2-Oct-2008 9:00 AM EDT
Liver Disease on the Rise, but New Treatments Coming
Texas Biomedical Research Institute

America faces an increase in liver cancer due to hepatitis C infections, but new treatments are on the horizon, scientists will report at the 15th International Symposium on Hepatitis C & Related Viruses, to be held in San Antonio from Oct. 5-9.

Released: 18-Feb-2009 5:00 PM EST
Scientists Develop New Model to Study How Cancer Grows and Spreads; May Find Use for New Diagnostics and Treatments
Texas Biomedical Research Institute

In an unexpected result, human cancer cells injected into a new animal model act in a manner similar to the way they do in humans, and may represent a new method for understanding and treating virtually all tumors.

Released: 26-Feb-2009 1:35 PM EST
Experimental Vaccine Protects Animals From Deadly Ebola Virus; May Prove Effective In Developing The First Human Vaccine
Texas Biomedical Research Institute

Protection against Ebola, one of the world's deadliest viruses, can be achieved by a vaccine produced in insect cells, raising prospects for developing an effective vaccine for humans, say scientists at the Southwest Foundation for Biomedical Research (SFBR) in San Antonio.

Released: 28-Jun-2009 9:00 PM EDT
Scientists Map Genome for Parasite Causing Widespread Infections
Texas Biomedical Research Institute

Scientists at the Southwest Foundation for Biomedical Research (SFBR) in San Antonio have for the first time constructed a genetic map of the parasite that causes schistosomiasis, a chronic intestinal infection that can damage internal organs and, in children, impair growth and cognitive development.

Released: 29-Sep-2009 5:10 PM EDT
San Antonio’s Southwest National Primate Research Center to Celebrate Tenth Anniversary
Texas Biomedical Research Institute

The Southwest National Primate Research Center (SNPRC) celebrates its 10th anniversary on October 1. The day-long program of events will include sessions on the center’s accomplishments in the areas of infectious diseases and biodefense, development and aging, chronic diseases and genomics.

30-Nov-2009 2:00 PM EST
New Drug Technology Produces Marked Improvement in Hepatitis C Therapy in Animals; May be Useful for Wide Range of Diseases
Texas Biomedical Research Institute

In a dramatic finding, a new drug for hepatitis C virus (HCV) infections that targets liver cells produced a substantial drop in blood levels of the virus in animals and continued to work up to several months after treatment, say scientists at the Southwest Foundation for Biomedical Research (SFBR) in San Antonio.

Released: 15-Jan-2010 8:00 PM EST
Llama Proteins Could Play a Vital Role in the War on Terror by Detecting World’s “Most Poisonous Poisons”
Texas Biomedical Research Institute

Scientists at the Southwest Foundation for Biomedical Research (SFBR) in San Antonio have for the first time developed a highly sensitive means of detecting the seven types of botulinum neurotoxins (BoNTs) simultaneously. The finding may lead to improved techniques for testing water and food supplies should BoNTs be used as a bioterrorism weapon.

Released: 13-Jul-2010 4:00 PM EDT
Smoking Has Significant Influence on Our Genes and They Way They Function
Texas Biomedical Research Institute

In the largest study of its kind, researchers at the Southwest Foundation for Biomedical Research (SFBR) have found that exposure to cigarette smoke can alter gene expression -- the process by which a gene's information is converted into the structures and functions of a cell. These alterations in response to smoking appear to have a wide-ranging negative influence on the immune system, and a strong involvement in processes related to cancer, cell death and metabolism.

Released: 15-Sep-2010 10:35 AM EDT
Scientists Find Gene Responsible for High-Cholesterol Levels in Blood
Texas Biomedical Research Institute

Scientists at the Southwest Foundation for Biomedical Research (SFBR) have found a gene that causes high levels of bad cholesterol to accumulate in the blood as a result of a high-cholesterol diet.

14-Jan-2011 3:00 PM EST
Dietary Restriction Early in Prenancy Has Negative Impact on Fetal Brain Development
Texas Biomedical Research Institute

A research team that includes scientists from the Southwest Foundation for Biomedical Research (SFBR) reported today that inadequate nutrition during early pregnancy impairs fetal brain development. The researchers found decreased formation of cell-to-cell connections, cell division and amounts of growth factors in the fetuses of mothers fed a reduced diet during the first half of pregnancy, in baboons located at SFBR’s Southwest National Primate Research Center.

17-Jun-2011 6:00 PM EDT
New Study Reveals How the Immune System Responds to Hepatitis “A” Virus
Texas Biomedical Research Institute

A surprising finding in a study comparing hepatitis C virus (HCV) with hepatitis A virus (HAV) infections in chimpanzees by a team that includes scientists from the Texas Biomedical Research Institute sheds new light on the nature of the body’s immune response to these viruses.

   
Released: 28-Oct-2011 10:10 AM EDT
Texas Biomed Develops New Approach to Study Depression; Finding May Lead to New Marker for Risk
Texas Biomedical Research Institute

Scientists at the Texas Biomedical Research Institute and Yale University have identified a new target area in the human genome that appears to harbor genes with a major role in the onset of depression.

2-Apr-2012 5:25 PM EDT
New Studies Highlight Setback, Advance in Global Malaria Fight
Texas Biomedical Research Institute

Emergence of resistance to the drug artemisinin in western Thailand has created a critical point in global efforts to control malaria worldwide. A second study, identifies a major region of the malaria parasite genome associated with resistance, raising hope that there will soon be effective molecular markers for monitoring the spread of resistance.

Released: 3-Jul-2012 2:35 PM EDT
New Animal Model May Lead to Treatments for Common Liver Disease
Texas Biomedical Research Institute

Scientists at Texas Biomed have developed the laboratory opossum as a new animal model to study the most common liver disease in the nation – afflicting up to 15 million Americans – and for which there is no cure.

29-Aug-2012 2:20 PM EDT
Antibody Prevents Hepatitis C Infection in Animal Model
Texas Biomedical Research Institute

A monoclonal antibody developed by MassBiologics of the University of Massachusetts Medical School (UMMS) and tested in an animal model at the Texas Biomedical Research Institute, prevents infection by the hepatitis C virus (HCV).

31-Oct-2012 5:00 PM EDT
Novel Process Represents Faster and More Economical Route for Devising Countermeasures Against Biothreats, Scientists Say
Texas Biomedical Research Institute

Texas Biomedical Research Institute scientists have developed a faster, less expensive route to screen suitable tests for bioterror threats and accelerate the application of countermeasures.

Released: 19-Nov-2012 11:00 AM EST
Texas Biomed Files Patent for a Novel HIV Vaccine Strategy
Texas Biomedical Research Institute

The Texas Biomedical Research Institute in San Antonio has applied for a patent for a genetically-engineered vaccine strategy to prevent HIV infection that targets the outer layers of body structures that are the first sites of contact with the virus.

Released: 10-Jan-2013 3:30 PM EST
Stem Cells Found to Heal Damaged Artery in Lab Study
Texas Biomedical Research Institute

Scientists at the Texas Biomedical Research Institute in San Antonio have for the first time demonstrated that baboon embryonic stem cells can be programmed to completely restore a severely damaged artery. These early results show promise for eventually developing stem cell therapies to restore human tissues or organs damaged by age or disease.

Released: 31-Jan-2013 10:30 AM EST
Gum Disease Found to Worsen Infection in Animal Model of AIDS
Texas Biomedical Research Institute

Texas Biomed scientists in San Antonio have found that moderate gum disease in an animal model exposed to an AIDS- like virus had more viral variants causing infection and greater inflammation. Both of these features have potential negative implications in long term disease progression, including other kinds of infections, the researchers say in a new report.

2-Apr-2013 5:00 PM EDT
Highly Lethal Ebola Virus Has Diagnostic Achilles' Heel for Biothreat Detection, Scientists Say
Texas Biomedical Research Institute

By screening a library of a billion llama antibodies on live Ebola viruses in the Texas Biomedical Research Institute’s highest biocontainment laboratory, scientists in San Antonio have identified a potential weakness in the make-up of these deadly agents that can immediately yield a sensitive test.

Released: 8-Apr-2013 5:00 PM EDT
Currently Used Drugs Found Active in Laboratory Mice Against Bioterror Threats
Texas Biomedical Research Institute

In the most extensive screen of its kind, Texas Biomed scientists in San Antonio have demonstrated the feasibility of repurposing already-approved drugs for use against highly pathogenic bacteria and viruses. The pathogens included emerging diseases and potential bioterror threats ranging from anthrax to the Marburg and Ebola viruses.

Released: 10-Apr-2013 1:00 PM EDT
Naturally-Occurring Substance Proves Effective Against Deadly Skin Cancer in Test Tube and Mice Studies
Texas Biomedical Research Institute

For the first time, scientists have demonstrated the mechanism of action of gossypin, a naturally-occurring substance found in fruits and vegetables, as a treatment for melanoma, which causes the majority of deaths from skin cancer.

25-Apr-2013 12:00 PM EDT
New Drug Stimulates Immune System to Kill Infected Cells in in an Animal Model of Hepatitis B Infection
Texas Biomedical Research Institute

A novel drug developed by Gilead Sciences and tested in an animal model at the Texas Biomedical Research Institute in San Antonio suppresses hepatitis B virus infection by stimulating the immune system and inducing loss of infected cells.

Released: 15-May-2013 12:00 PM EDT
Four Genes Identified That Influence Levels of 'Bad' Cholesterol
Texas Biomedical Research Institute

Scientists at the Texas Biomedical Research Institute in San Antonio have identified four genes in baboons that influence levels of “bad” cholesterol. This discovery could lead to the development of new drugs to reduce the risk of heart disease.

Released: 24-Jun-2013 3:00 PM EDT
Michael Olivier, Expert in Genes and Proteins and Their Role in Human Disease, Appointed to Genetics Faculty at Texas Biomedical Research Institute
Texas Biomedical Research Institute

Michael Olivier, Ph.D., professor of physiology and director of the Wisconsin Center of Excellence in Genomics Science at the Medical College of Wisconsin in Milwaukee, has been appointed to the position of Scientist in the Department of Genetics at the Texas Biomedical Research Institute.

Released: 10-Jul-2013 12:25 PM EDT
Ruth Ruprecht, Pioneer in AIDS-Related Research and Vaccines, and in Breast Cancer, Appointed to Virology Position at Texas Biomed
Texas Biomedical Research Institute

Ruth M. Ruprecht, M.D., Ph.D., a professor of medicine at Harvard Medical School and the Dana-Farber Cancer Institute in Boston, has been appointed to the position of Scientist and Director of the AIDS Research Program in the Department of Virology and Immunology at the Texas Biomedical Research Institute.

Released: 11-Jul-2013 10:30 AM EDT
Mexican American Youth Show Sighs of Metabolic Syndrome: Early Screening Critical to Reduce Risk of Future Diabetes, Heart Disease
Texas Biomedical Research Institute

Mexican American children are experiencing substantial burdens of obesity, pre-diabetes, and other health problems which historically would have been expected to develop much later in life. The findings of a new study by Texas Biomed scientists in San Antonio argue for early screening and intervention to delay or avoid chronic health problems as these children age.

Released: 4-Nov-2013 3:00 PM EST
Brain Aging Is Conclusively Linked to Genes
Texas Biomedical Research Institute

For the first time in a large study sample, the decline in brain function in normal aging is conclusively shown to be influenced by genes, say researchers from the Texas Biomedical Research Institute in San Antonio and Yale University.

Released: 14-Nov-2013 1:00 PM EST
New Study May Help Explain Why Some People Taking Drugs for Osteoporosis Are at Risk for Fractures
Texas Biomedical Research Institute

Research with baboons at the Texas Biomedical Research Institute in San Antonio may help explain why some people who take bone-strengthening drugs like bisphosphonates are at-risk for atypical fractures in the long bones in their legs.

15-Nov-2013 2:00 PM EST
Study of Human Blood Fluke Parasites Identifies Drug Resistance Mutations; Raises Hope for Improved Therapies
Texas Biomedical Research Institute

An international group of scientists lead by Tim Anderson Ph.D., at the Texas Biomedical Research Institute and Philip LoVerde Ph.D., at the University of Texas Health Science Center at San Antonio has identified the mutations that result in drug resistance in a parasite infecting 187 million people in South America, Africa and Asia. The new finding allows detailed understanding of the drugs’ mechanism of action and raises prospects of improved therapies.

30-Apr-2014 1:00 PM EDT
A New Method for Isolating and Genome Sequencing Malaria Parasites Will Aid in the Understanding of These Infections
Texas Biomedical Research Institute

A new method for isolating and genome sequencing an individual malaria parasite cell has been developed by Texas Biomed researchers in San Antonio and their colleagues. This advance will allow scientists to improve their ability to identify the multiple types of malaria parasites infecting patients and lead to ways to best design drugs and vaccines to tackle this major global killer.

Released: 11-Jun-2014 12:00 PM EDT
Texas Biomed Regenerative Medicine Program Expands With Two New Research Scientists
Texas Biomedical Research Institute

Texas Biomedical Research Institute has recruited two new research scientists to its Southwest National Primate Research Center (SNPRC) who will focus on regenerative medicine, working with animal models to develop human stem cell therapies for medical conditions such as Parkinson's disease, degenerative diseases of the eye and muscular dystrophy.


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