Curated News: JAMA

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Released: 23-Nov-2022 3:25 PM EST
Vitamin D fails to reduce statin-associated muscle pain
Northwestern University

Patients who take statins to lower high cholesterol levels often complain of muscle pains, which can lead them to stop taking the highly effective medication and put them at greater risk of heart attack or stroke.

18-Nov-2022 11:05 AM EST
Youth Suicide Rates in U.S. Linked to Shortages of Mental Healthcare Workers at County Level
Ann and Robert H. Lurie Children's Hospital of Chicago

Youth suicide rate increased as county levels of mental health professional shortages increased, after adjusting for county demographic and socioeconomic characteristics, according to the first national study to assess this association. The association remained significant for youth suicides by firearms. Findings were published in the journal JAMA Pediatrics.

Released: 17-Nov-2022 12:45 PM EST
Homelessness, hospitals and mental health: Study shows impacts and costs
Michigan Medicine - University of Michigan

A new study that harnesses a new form of data on hospital patients' housing status reveals vast differences in diagnoses between patients with and without housing issues who are admitted to hospitals. This includes a sharp divide in care for mental, behavioral and neurodevelopmental conditions.

Newswise: New Study Shows Segregation in U.S. Counties Influence Cancer Risk and Mortality
15-Nov-2022 12:00 PM EST
New Study Shows Segregation in U.S. Counties Influence Cancer Risk and Mortality
American Cancer Society (ACS)

A new study led by researchers at the American Cancer Society and Clemson University shows residential racial and economic segregation was associated with cancer mortality at the county level in the United States.

Released: 16-Nov-2022 3:00 PM EST
Study compares adverse events after two types of bariatric surgery in adolescents
Michigan Medicine - University of Michigan

Adolescents who underwent sleeve gastrectomy, a type of weight-loss surgery that involves removing part of the stomach, were less likely to go the emergency room in the five years after their operations than those who had their stomachs divided into pouches through gastric bypass surgery, according to new research.

16-Nov-2022 2:00 PM EST
MD Anderson Research Highlights for November 16, 2022
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recent basic, translational and clinical cancer research from MD Anderson experts. Current advances include a promising targeted therapy combination for patients with relapsed/refractory acute myeloid leukemia (AML), a link between the gut microbiome and therapy-related neutropenic fever, a novel therapeutic target for immunotherapy-related colitis, a telementoring model for training providers on cervical cancer prevention in limited-resource areas, a new understanding of the prognostic value of RUNX1 mutations in AML, and insights into the effects of opioid use on the pain sensitivity pathway.

   
Released: 16-Nov-2022 11:25 AM EST
National quality improvement initiative led by the American College of Surgeons successfully helped address pandemic-related cancer screening deficits
American College of Surgeons (ACS)

A national Return-to-Screening effort initiated and led by the American College of Surgeons (ACS) helped restore cancer screenings to pre-pandemic levels and contributed to a significant number of additional screening tests, according to new research published in JAMA Network Open.

Newswise: Nicotine Pouch Sales Rising; Products with Highest Concentration Levels also Increasing, New Study Shows
Released: 16-Nov-2022 11:15 AM EST
Nicotine Pouch Sales Rising; Products with Highest Concentration Levels also Increasing, New Study Shows
American Cancer Society (ACS)

A new study led by researchers at the American Cancer Society shows overall sales of nicotine pouches increased during 2019-2022. The data also showed sales of 8mg nicotine concentration level (highest available) products rose more rapidly than those with different concentration levels.

Newswise: Weak evidence that interventions to boost housing affordability and stability promote better health
Released: 16-Nov-2022 9:00 AM EST
Weak evidence that interventions to boost housing affordability and stability promote better health
University of California, Los Angeles (UCLA), Health Sciences

Research finds low-certainty evidence that programs such as emergency rent assistance, legal assistance with waitlist priority for public housing, long-term rent subsidies and homeownership assistance lead to positive health outcomes.

Released: 14-Nov-2022 4:25 PM EST
Bariatric Surgery Decreases Risk of Heart Disease
Rutgers University-New Brunswick

A Rutgers study of obese adults, all with nonalcoholic fatty liver disease (NAFLD) and morbid obesity (body mass index > 40), has shown that those who underwent bariatric surgery suffered far fewer extreme cardiovascular events subsequently.

Released: 14-Nov-2022 10:05 AM EST
Major financial pain follows major injury, study shows
Michigan Medicine - University of Michigan

The percentage of working-age people with medical debts so overdue that a collection agency has gotten involved, and the size of those debts, were both much higher in those who had suffered a traumatic injury serious enough to require a hospital stay in the last two years, compared with others like them.

Newswise: Study finds inherited link to appendix cancer
10-Nov-2022 11:10 AM EST
Study finds inherited link to appendix cancer
Vanderbilt University Medical Center

One of every 10 patients with appendiceal cancer carries a germline genetic variant associated with cancer predisposition, according to a study in JAMA Oncology that is the first to show inherited risk factors for this rare cancer.

Released: 11-Nov-2022 12:05 PM EST
MedStar Health Researchers Examine Alleged Misrepresentation of EHR Capabilities with Potentially Far-Reaching Patient Safety Implications
MedStar center

Researchers at MedStar Health, Brigham and Women's Hospital, and the University of Utah found electronic health record (EHR) vendor misconduct may have led to widespread use of suboptimal products for more than 70,000 clinicians across the country, as published today in JAMA Health Forum.

   
9-Nov-2022 4:35 PM EST
New Tool Predicts Risk of Hospital Readmission for Children Before Discharge
Ann and Robert H. Lurie Children's Hospital of Chicago

Readily available electronic health record (EHR) data can be used to reliably identify readmission risk for children of all ages while they are still in the hospital, according to a study from Ann & Robert H. Lurie Children’s Hospital of Chicago published in the journal JAMA Network Open. The newly developed and validated tool will be key in efforts to reduce hospitalizations within 30 days of discharge, which also should help free up scarce pediatric hospital beds.

Released: 10-Nov-2022 6:20 PM EST
Helping patients with addiction tackle their health needs
Kaiser Permanente

n intervention that teaches patients in addiction treatment how to better connect with their primary care medical team on both mental and physical health concerns resulted in long-term benefits over 5 years, including more primary care use and fewer substance-related emergency department visits, Kaiser Permanente researchers have found.

Released: 10-Nov-2022 2:00 PM EST
Non-physician practitioners in the ED associated with 5.3% more imaging use
Harvey L. Neiman Health Policy Institute

A new Harvey L. Neiman Health Policy Institute study found when patients are treated in the Emergency Department by non-physician practitioners (physicians assistants and nurse practitioners), there were 5.3% more imaging studies performed than if patients were seen only by physicians. This JAMA Network Open study was based on a nationally representative sample of Medicare fee-for-service beneficiaries with 16,922,274 ED visits between 2005 and 2020.

7-Nov-2022 1:00 PM EST
Mindfulness-Based Stress Reduction Is as Effective as an Antidepressant Drug for Treating Anxiety Disorders
Georgetown University Medical Center

A guided mindfulness-based stress reduction program was as effective as use of the gold-standard drug -- the common antidepressant drug escitalopram -- for patients with anxiety disorders, according to results of a first-of-its-kind, randomized clinical trial led by researchers at Georgetown University Medical Center.

7-Nov-2022 2:45 PM EST
CHOP Researchers Find COVID-19 Vaccination Leads to Higher Antibody Levels than Natural Infection in Both Pregnant People and their Babies
Children's Hospital of Philadelphia

Pregnant people who received one of the mRNA COVID-19 vaccines had 10-fold higher antibody concentrations than those who were naturally infected with SARS-CoV-2, a finding that was also observed in their babies, according to a new study by researchers at Children’s Hospital of Philadelphia (CHOP) and the University of Pennsylvania. The study, published today in JAMA Network Open, also found that vaccine timing played an important role in maximizing the transfer of antibodies, with antibodies detected as early as 15 days after the first vaccine dose and increasing for several weeks after.

Released: 7-Nov-2022 11:05 AM EST
Biases in cardiometabolic research put minority women's lives at risk
University of Michigan

Biases in heart disease and metabolic disorder—also known as cardiometabolic—studies are putting the lives of midlife Black and Hispanic women in jeopardy.

Released: 7-Nov-2022 11:05 AM EST
Study Finds Automated Texts Decrease Odds of Rehospitalization
Perelman School of Medicine at the University of Pennsylvania

Text messages sent automatically from patients’ primary care office after hospitalization were tied to decreased odds of needing further emergency care

Released: 4-Nov-2022 4:00 PM EDT
Extreme Temperatures Take Deadly Toll on People in Texas Prisons, Study Finds
Brown University

The U.S. has the world’s largest population of prisoners, and Texas holds more incarcerated people than any other state.

2-Nov-2022 4:05 PM EDT
Could “Choosing Wisely” Help Fight Health Worker Burnout?
Michigan Medicine - University of Michigan

As hospitals, clinics and health systems seek to overcome the wave of burnout and departures among their clinical staff, they might want to adopt an approach that they’ve used over the past decade in clinical care: choosing wisely.

Released: 3-Nov-2022 11:00 AM EDT
MD Anderson Research Highlights for November 3, 2022
University of Texas MD Anderson Cancer Center

The University of Texas MD Anderson Cancer Center’s Research Highlights provides a glimpse into recent basic, translational and clinical cancer research from MD Anderson experts.

   
3-Nov-2022 7:05 AM EDT
Study Finds That Patients with Cancer and a Suppressed Immune System Are at High Risk for Severe COVID if Treated with Systemic Drug Therapies
Dana-Farber Cancer Institute

Patients with cancer and a weakened immune system who are treated with immunotherapies tend to fare far worse from COVID-19 than those who haven't received such therapies in the three months before their COVID diagnosis, show findings in a new study by researchers at Dana-Farber Cancer Institute, and across the U.S., Canada, and Mexico. Researchers found worse outcomes in both the disease itself as well as the fierce immune response that sometimes accompanies it.

Newswise: New Study Shows Recently Diagnosed Adult Cancer Survivors at Higher Risk for Bone Fractures
1-Nov-2022 10:05 AM EDT
New Study Shows Recently Diagnosed Adult Cancer Survivors at Higher Risk for Bone Fractures
American Cancer Society (ACS)

Adult cancer survivors, particularly those diagnosed within five years and/or have a history of chemotherapy, have an increased risk for bone fractures, specifically pelvic and vertebral fractures, compared to older adults without cancer, according to a new large study by researchers at the American Cancer Society.

Newswise: Researchers Find No Decrease in Preterm Births with Vaginal Progesterone
Released: 1-Nov-2022 4:30 PM EDT
Researchers Find No Decrease in Preterm Births with Vaginal Progesterone
UT Southwestern Medical Center

Vaginal progesterone, a hormone treatment considered the standard of care for preventing preterm birth in at-risk pregnant women, may not be effective, according to UT Southwestern Medical Center researchers.

Released: 1-Nov-2022 2:20 PM EDT
Youngest Girls Who Get Pregnant Have Highest Risk of Poor Outcomes, Study Finds
University of Maryland School of Medicine

Pregnant teens in the U.S. have long been known to face increased health risks and pregnancy complications, but a new study for the first time finds that girls ages 13 or younger who get pregnant face even greater risks. These very young girls are significantly more likely to experience preterm birth, cesarean delivery, and admission to the intensive care unit (ICU) compared to older pregnant teens.

Newswise: Breast Cancer Survivor Uses Personal and Professional Experience to Help Others
Released: 1-Nov-2022 8:05 AM EDT
Breast Cancer Survivor Uses Personal and Professional Experience to Help Others
Rensselaer Polytechnic Institute (RPI)

Rensselaer Polytechnic Institute Professor of Computer Science, Cognitive Science, and Industrial and Systems Engineering Deborah McGuinness was diagnosed with breast cancer nearly 10 years ago. Her treatments were emotionally and physically challenging: McGuinness endured six months of chemotherapy, 33 radiation treatments, and four surgeries before emerging with current “no evidence of disease” status.

Released: 31-Oct-2022 8:05 PM EDT
Use of DNA Biomarkers for Detecting Early-Stage HPV-Positive Oropharynx Cancers Has Limitations
Brigham and Women’s Hospital

Oropharynx cancers caused by human papillomavirus (HPV) have risen dramatically over the years, superseding tobacco use and heavy drinking as the primary driver of new cases.

Newswise: Treated or Not, COVID-19 Recurrence Seems Symptomatic for Some
Released: 31-Oct-2022 12:10 PM EDT
Treated or Not, COVID-19 Recurrence Seems Symptomatic for Some
University of California San Diego

UC San Diego researchers and others report that more than one-third of the COVID-19 patients who did not receive any treatment experienced complete resolution of symptoms for at least two consecutive days, but then subsequently reported a return of symptoms.

Released: 31-Oct-2022 12:05 PM EDT
Industry payments to physicians and advanced practice clinicians compared
Duke Health

A new study led by Duke Health found that advanced practice clinicians received more payments from drug companies, while physicians accepted more funds from medical device companies. The same proportion of each group accepted payments, but the physicians received a much greater sum.

26-Oct-2022 5:55 PM EDT
Differences in State Medicaid Programs for Children with Medical Complexity May Lead to Care Inequity
Ann and Robert H. Lurie Children's Hospital of Chicago

Medicaid eligibility and coverage for children with medical complexity vary substantially by state, which gives rise to health equity concerns, especially if families move across state lines, according to a study from Ann & Robert H. Lurie Children’s Hospital of Chicago published in the journal JAMA Network Open. The study focused on Medicaid programs for these children beyond the traditional family income-based eligibility.

27-Oct-2022 10:25 AM EDT
Study Finds Persistent Disparities in Access to Prenatal Care Among Pregnant People Based on Citizenship Status and Education Level
Mount Sinai Health System

Findings suggest exclusions to Medicaid because of immigration status may increase risk for maternal health care disparities in some immigrant populations

Released: 26-Oct-2022 2:10 PM EDT
Controlling Gut Flora Can Reduce Mortality in Critically Ill Patients on Life Support
George Institute for Global Health

Preventing severe lung infections in mechanically ventilated intensive care patients by applying topical antibiotics to the upper digestive tract results in a clinically meaningful improvement in survival, new research shows.

Released: 25-Oct-2022 3:10 PM EDT
New Drug Is Found Effective for Treating Complicated Urinary Tract Infections
Rutgers University-New Brunswick

An international study led by a Rutgers scientist comparing new and older treatments against complicated urinary tract infections has found a new drug combination to be more effective, especially against stubborn, drug-resistant infections.

21-Oct-2022 6:15 PM EDT
Telehealth Follow-Up Associated with Increased Returns and Hospitalizations After Emergency Department Visit
University of California, Los Angeles (UCLA), Health Sciences

Telehealth follow-up consultations following an emergency department visit were associated with 28 more repeat ED encounters and nearly 11 more return hospital admissions per 1000 patients compared with in-person follow-ups,

Released: 24-Oct-2022 8:05 PM EDT
Video Gaming May Be Associated with Better Cognitive Performance in Children
NIH National Institute on Drug Abuse (NIDA)

A study of nearly 2,000 children found that those who reported playing video games for three hours per day or more performed better on cognitive skills tests involving impulse control and working memory compared to children who had never played video games.

   
Released: 21-Oct-2022 4:10 PM EDT
US Food Insufficiency Spiked by 25% After Monthly Child Tax Credits Expired
Boston University School of Public Health

In the months after the advance federal Child Tax Credit cash payments ended in December 2021, low-income families with children struggled the most to afford enough food.

Released: 21-Oct-2022 2:25 PM EDT
Researchers Examine What Happens When Patients Can Choose Concurrent Dialysis and Hospice Care
Brigham and Women’s Hospital

Today, patients utilizing their Medicare Hospice Benefits with end-stage kidney disease (ESKD) are forced to make the traumatic choice between continuing dialysis or enrolling in hospice.

Released: 21-Oct-2022 1:50 PM EDT
Effect of Ivermectin vs Placebo on Time to Sustained Recovery in Outpatients with Mild to Moderate COVID-19
JAMA - Journal of the American Medical Association

Among outpatients with mild to moderate COVID-19, treatment with ivermectin, compared with placebo, did not significantly improve time to recovery in this trial that enrolled more than 1,500 participants in the United States.

Newswise: Oncology Therapy at the End-of-Life: Have We Missed the Mark?
Released: 21-Oct-2022 9:55 AM EDT
Oncology Therapy at the End-of-Life: Have We Missed the Mark?
Yale Cancer Center/Smilow Cancer Hospital

In a study published today in JAMA Oncology, researchers at Yale Cancer Center in collaboration with researchers from Flatiron Health, Inc., revealed that despite recommendations, aggressive cancer care at the end-of-life persists and there has been a substantial transition from the use of chemotherapy to immunotherapy.

Newswise: mRNA Vaccines Significantly Reduce Severity of Delta, Omicron COVID-19 Infections
Released: 20-Oct-2022 7:05 PM EDT
mRNA Vaccines Significantly Reduce Severity of Delta, Omicron COVID-19 Infections
University of Utah Health

People who have received two or three doses of an mRNA COVID-19 vaccine are significantly more likely to have milder illnesses if infected with the Delta or Omicron coronavirus variants than those who are unvaccinated, according to a nationwide study involving a team of University of Utah researchers.

19-Oct-2022 12:25 PM EDT
Sexual assault related ER visits increase more than tenfold
Michigan Medicine - University of Michigan

An increasing number of people are seeking emergency medical help for sexual assault, according to a new study.

Released: 18-Oct-2022 4:05 PM EDT
Comparative safety of Pfizer-BioNTech COVID-19 vaccine vs non–SARS-CoV-2 vaccines in children younger than age 5
JAMA - Journal of the American Medical Association

The symptoms reported after administration of the Pfizer-BioNTech COVID-19 vaccine were comparable overall to those for approved non–SARS-CoV-2 vaccines in this study including 7,800 children younger than age 5.

Released: 18-Oct-2022 3:05 PM EDT
Increased electronic health record time associated with enhanced quality outcomes in primary care
Brigham and Women’s Hospital

In the United States, the electronic health record (EHR) has become increasingly prevalent in the day-to-day practice of physicians, with primary care physicians (PCPs) spending the most time in the EHR.

13-Oct-2022 1:35 PM EDT
Medically Tailored Meals Could Save U.S. Nearly $13.6 Billion Per Year
Tufts University

Expanding programs that make and deliver medically tailored meals to people with serious, diet-sensitive diseases could lead to fewer hospitalizations nationally and a net cost savings of approximately $13.6 billion each year, according to a new study led by Tufts University researchers.

Released: 14-Oct-2022 1:05 PM EDT
Some Younger Kids May Need Screening for Anxiety in Primary Care
Ann and Robert H. Lurie Children's Hospital of Chicago

Some children aged 7 years and younger may benefit from screening for anxiety in primary care, according to an editorial published in JAMA by John Walkup, MD, Chair of Pritzker Department of Psychiatry and Behavioral Health at Ann & Robert H. Lurie Children’s Hospital of Chicago, and colleagues. The authors respond to the US Preventive Services Task Force recommendation that children be screened for anxiety at 8-18 years of age.

Released: 13-Oct-2022 2:05 PM EDT
Risk of Severe Breakthrough COVID-19 Infection Is Higher for People With HIV With Moderately Low CD4 Cell Counts
Johns Hopkins Bloomberg School of Public Health

People with HIV who have moderate immune suppression appear to be at greater risk of severe COVID-19 “breakthrough” infection after vaccination, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health.



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