Moffitt Cancer Center has treated its first patient in an investigator-initiated, phase 1 clinical trial investigating the safety and efficacy of a chimeric antigen receptor T-cell (CAR T) therapy for prostate cancer that has metastasized to the bone.
For patients with locally advanced prostate cancer, combined treatment with chemotherapy and hormonal therapy offers extended control of prostate-specific antigen (PSA) levels, compared to hormonal therapy alone, reports a study in the April issue of The Journal of Urology®, an Official Journal of the American Urological Association (AUA). The journal is published in the Lippincott portfolio by Wolters Kluwer.
Researchers from the University of Michigan Health Rogel Cancer Center have created a urine-based test that detects pieces of DNA fragments released by head and neck tumors. The test could potentially facilitate early detection of this cancer type, which currently does not have a reliable screening method.
UWF faculty, serving as evaluators for Florida's Cancer Prevention and Control Program since 2018, recently had their contract renewed for $680,000 over four years due to excellent performance, as acknowledged by the CDC.
Researchers from Analysis Group, a global leader in health economics and outcomes research (HEOR), have coauthored the first large-scale study that revealed racial disparities in treatment, survival, and access to care among patients with metastatic castration-sensitive prostate cancer (mCSPC) since the first novel hormonal therapy was approved in 2018.
Researchers at Case Western Reserve University’s School of Medicine believe they have found information that could lead to developing new treatment options for people with metastatic colorectal cancer.
“Support is the most important part of cancer treatment,” says El Paso resident Rosario De Anda, who was diagnosed with breast cancer. “When I started to feel that sense of hope, I began to lose the fear. It made me want to live and push forward.” she adds.
MD Anderson and CureVac today announced a co-development and licensing agreement to develop novel mRNA-based cancer vaccines.
Smith is a nationally recognized academic radiologist with expertise in body and oncologic imaging, clinical trials and imaging research and the application of artificial intelligence (AI) in imaging and medicine.
Pesquisadores da Mayo Clinic criaram recentemente uma nova classe de algoritmos com inteligência artificial (IA) chamada IA orientada por hipóteses; se trata de um caminho alternativo dos modelos tradicionais de IA que aprendem apenas com dados.
Investigadores de Mayo Clinic crearon recientemente una nueva clase de algoritmos con inteligencia artificial (IA) llamada IA impulsada por hipótesis; se trata de una vía alternativa a los modelos tradicionales de IA que aprenden solo con datos.
The National Comprehensive Cancer Network (NCCN) and the NCCN Foundation announce five winners for the 2024 NCCN Foundation Young Investigator Awards (YIA).
An FDA advisory committee (ODAC) voted 12-0 today in favor of a major shift in how the agency evaluates new treatments for multiple myeloma. If approved by the FDA, the result will be faster approval of new treatments for multiple myeloma.
Neli Ulrich joins a select group of recipients recognized for their impactful work in science and technology in Utah.
The Vice Dean for Clinical Science Research is a new leadership role accountable for successfully implementing the research strategic plan as it pertains to clinical science within the overall BSD/PSOM research mission.
Himelhoch comes to UChicago from the University of Kentucky, where his public health research has focused on interventions for those with HIV and substance use disorders and cancer control.
The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.
A research team from the National University of Singapore (NUS) has unearthed new findings which may help explain the connection between cancer risk and poor diet, as well as common diseases like diabetes, which arise from poor diet.
NIBIB-supported researchers have developed a smart nanoprobe designed to infiltrate prostate tumors and send back a signal using an optical imaging technique known as Raman spectroscopy.
A University of Delaware professor is testing interventions that address the psychosocial needs of African American patients with cancer and their families, with the goal of boosting communication skills and decreasing anxiety and depression for children whose parents have cancer.
Human papillomavirus (HPV) is the second most common cancer-causing virus, accounting for 690,000 cervical and other cancers each year worldwide.
More than 1,700 oncology professionals attended National Comprehensive Cancer Network meeting in Orlando and online, featuring clinical and administrative updates for improving cancer care worldwide, plenary sessions on Lynch syndrome and drug shortages, plus nearly 200 poster abstracts with new research.
Researchers have unveiled a microfluidic device that significantly improves the separation of tumor cells and clusters from malignant effusions. This novel technology promises to advance the diagnosis and treatment monitoring of cancer by enabling the high-throughput, continuous-flow ternary separation of single tumor cells, tumor cell clusters, and white blood cells (WBCs) from clinical pleural or abdominal effusions.
Skin Cancer Champions is a safe and compassionate place where patients, their caregivers, and clinicians can ask questions, and share experiences.
In the April issue of AJG: New clinical science and reviews on the effectiveness of H. pylori therapies, privacy considerations around video endoscopy as big data, liver disease and cirrhosis, and dysplasia detection in IBD.
A study by Joemy Ramsay, PhD, suggests families with infertile male relatives may face elevated cancer risks. Tapping into genetic data, families could help personalize cancer risk assessments.
Cleveland Clinic has started using a recently FDA-approved ultrasound device to treat liver tumors. The non-invasive technology, called histotripsy, uses brief high-intensity ultrasound pulses that disrupt and kill the targeted tumor cells.
CAR T cell therapy has revolutionized the way certain types of cancer are treated, and the longer those CAR T cells live in a patient’s body, the more effectively they respond to cancer. Now, researchers have found that a protein called FOXO1 improves the survival and function of CAR T cells, which may lead to more effective CAR T cell therapies and could potentially expand its use in difficult-to-treat cancers.
Researchers at Washington University School of Medicine in St. Louis and Whiterabbit.ai showed that AI assistance potentially could improve breast-cancer screening by reducing the number of false positives without missing true positives.
Researchers at IRB Barcelona report mutation rate variation across the human genome. Regions with low mutation rates correlate with hypomethylation (low methylation levels), a way cells control which genes are turned on or off.
Three early-phase clinical studies presented by researchers from The University of Texas MD Anderson Cancer Center at the American Association for Cancer Research (AACR) Annual Meeting 2024 show promising initial data for patients with lymphoma, gastric or gastroesophageal junction cancers, and specific molecularly selected tumors.
An educational video piloted by Penn Medicine’s Abramson Cancer and designed to reach diverse populations and address prostate cancer screening disparities helped increase knowledge and reduce uncertainty about screening.
St. Jude Children’s Research Hospital today announces the survivorship portal, part of the St. Jude Cloud ecosystem, for unparalleled data analysis and visualization.
Cervical cancer, often caused by persistent human papillomavirus (HPV) infections, remains a public health challenge worldwide despite falling diagnoses related to the success of the HPV vaccine[GR1] in young adult women.
Scientists have unraveled the mechanisms of the Cyclic guanosine monophosphate-adenosine monophosphate synthase-stimulator of interferon genes (cGAS-STING) signaling pathway activated by micronuclei, as well as its significant effects on tumor immunity.
Susan G. Komen commends passage of HB 115 in Kentucky, which removes out-of-pocket costs for diagnostic and supplemental imaging. This is a critical form of breast cancer screening for some high-risk individuals and an important step in determining the need for a biopsy to rule out or confirm breast cancer.
Recent work by St. Jude Children’s Research Hospital scientists discovered which tumor cells resist treatment and why. By characterizing B-cells’ developmental stages, they designed and tested a drug combination to effectively treat resistant B-cell leukemia.
RUSH has opened a new outpatient center in Hinsdale to expand care in Chicago’s western suburbs. RUSH Hinsdale brings primary and specialty care to Hinsdale and surrounding communities — including reproductive endocrinology and infertility care. The center also offers lab services and dedicated parking.
Obesity is associated with a higher risk of developing at least 13 types of cancer — and worse outcomes after diagnosis. But lung cancer seems to be an exception: Studies have shown that patients with a high body mass index (BMI) experience a lower risk of disease recurrence and longer survival after surgical treatment — an irregularity called “the obesity paradox.”
The first-in-class PARP1-selective inhibitor saruparib demonstrated encouraging early efficacy and a favorable safety profile in patients with homologous recombination repair (HRR)-deficient breast cancers, according to results from the Phase I/II PETRA trial led by researchers at The University of Texas MD Anderson Cancer Center.
Combining the KRAS G12C inhibitor adagrasib with the anti-EGFR antibody cetuximab demonstrated promising anti-tumor effects in patients with KRAS G12C-mutated metastatic colorectal cancer (CRC), according to pooled results from the Phase I/II KRYSTAL-1 trial reported by researchers from The University of Texas MD Anderson Cancer Center.
Memorial Sloan Kettering Cancer Center (MSK) is proud to announce that Jeffrey A. Drebin, MD, PhD, has been named President-Elect of the American Surgical Association (ASA) for 2024.
Um novo estudo multicentro e internacional sugere que as pessoas portadoras de câncer de mama triplo-negativo em estágio precoce, com níveis elevados de células imunes dentro desses tumores, podem ter um baixo nível de recorrência e melhores taxas de sobrevivência, mesmo quando não houve tratamento com quimioterapia.
Un nuevo estudio multicéntrico e internacional indica que las personas que tienen cáncer de mama triple negativo (TNBC) en etapa inicial y niveles elevados de células inmunitarias en sus tumores pueden tener un menor riesgo de recurrencia y mejores tasas de supervivencia, incluso cuando no se tratan con quimioterapia.
WHAT: Researchers from the Johns Hopkins Kimmel Cancer Center will present results from several research studies and accept honors and awards at the American Association for Cancer Research (AACR) annual meeting.
The National Comprehensive Cancer Network® (NCCN®)—a nonprofit devoted to patient care, research, and education—is announcing the election of Matt Kalaycio, MD, FACP, as Chair of the Board of Directors, with Christopher H. Lieu, MD, elected as Vice-Chair, succeeding Dr. Kalaycio in the position he has held since 2022.
A research team led by the University of California, Irvine has built the first genetic reference maps for short lengths of DNA repeated multiple times which are known to cause more than 50 lethal human diseases, including amyotrophic lateral sclerosis, Huntington’s disease and multiple cancers.
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