The National Science Foundation's program to build research capacity across the country has awarded a $20 million grant to support Iowa researchers working to make the state a leader in advanced biomanufacturing. The researchers will use microbes to produce plastics for 3D printing, fibers for flexible and rigid materials and proteins for medical diagnostics and therapeutics.
Wistar Institute has formed a collaboration with the Pennsylvania Biotechnology Center and the Baruch S. Blumberg Institute to accelerate the advancement of “bench to bedside” biomedical research discoveries in the tri-state region.
Researchers from the University of California, Irvine have developed a DNA enzyme – or DNAzyme – that can distinguish between two RNA strands inside a cell and cut the disease-associated strand while leaving the healthy strand intact. This breakthrough “gene silencing” technology could revolutionize the development of DNAzymes for treating cancer, infectious diseases and neurological disorders.
Oak Ridge National Laboratory scientists led the development of a supply chain model revealing the optimal places to site farms, biorefineries, pipelines and other infrastructure for sustainable aviation fuel production.
University of Minnesota Twin Cities researchers have developed a groundbreaking new diagnostic technique that will allow for faster and more accurate detection of neurodegenerative diseases that affect humans, such as Alzheimer's and Parkinson's, and similar diseases that affect animals, such as chronic wasting disease (CWD) and mad cow disease.
The Association of Biomolecular Resource Facilities (ABRF) 2023 Annual Meeting will be held May 7-10 at the Sheraton Boston Hotel.
University of Maryland School of Medicine (UMSOM) Dean Mark T. Gladwin, MD, announced today that Bradley A. Maron, MD, Associate Professor of Medicine at Brigham & Women’s Hospital (BWH) and Harvard Medical School (HMS), and Co-Director of the Pulmonary Vascular Disease Center at the VA Boston Healthcare System, has been appointed Co-Director of the UMB’s new Institute for Health Computing (UM-IHC), Director of Scientific Operations for the UM-IHC at UMSOM, as well as Senior Associate Dean for Precision Medicine at the UMSOM, effective May 1, 2023.
An upgraded computational tool from St. Jude Children’s Research Hospital can find potentially druggable hidden drivers of cancer and other biological processes using multi-omics data.
Using a “spooky” phenomenon of quantum physics, Caltech researchers have discovered a way to double the resolution of light microscopes.
Applying machine learning models, a type of AI, to data collected passively from wearable devices can identify a patient’s degree of resilience and well-being, according to investigators at the Icahn School of Medicine at Mount Sinai in New York. The findings, reported in the May 2nd issue of JAMIA Open, support wearable devices, such as the Apple Watch®, as a way to monitor and assess psychological states remotely without requiring the completion of mental health questionnaires.
Gene-editing therapy aimed at two targets – HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that helps the virus get into cells – can effectively eliminate HIV infection. The study is the first to combine a dual gene-editing strategy with antiretroviral drugs to cure animals of HIV-1.
What if your physician could predict if—or when—you might experience a heart attack, cardiac arrest or another heart-related problem?
Researchers, including from NTNU, are breeding bacteria-free fish fry. This pursuit is more important than you might think. The researchers have studied how bacteria affect the growth, genes and mucous membranes of the fish.
This agreement will enable FAU and Insightec to collaborate to advance scientific knowledge about the use of focused ultrasound to treat brain diseases, including Parkinson’s disease and Alzheimer’s disease. By harnessing acoustic energy, Insightec’s innovative technology uses focused ultrasound to treat diseases in different ways.
Scientists have been studying the possibility of electrical signal transfer between mushrooms and across trees via the mycelial networks. It is thought that fungi generate electrical signals in response to external stimuli and use these signals to communicate with each other, coordinating growth and other behavior.
Seven University of Utah Health projects have received seed grants that could promote the development and use of more scientifically based digital health applications in daily health care.
Multiple myeloma is a rare blood cancer caused by the uncontrolled multiplication of abnormal plasma cells. These plasma cells are a special type of white blood cells that play an important role in the immune system by producing essential antibodies in the bone marrow and lymph nodes.
Researchers have developed a biosynthetic “clock” that keeps cells from reaching normal levels of deterioration related to aging. They engineered a gene oscillator that switches between the two normal paths of aging, slowing cell degeneration and setting a record for life extension.
Developed by a research team from NYU Tandon School of Engineering and the Massachusetts Institute of Technology (MIT), a new electrical “pill”, dubbed FLASH, delivers electrical impulses to the stomach lining once it's swallowed and may be able to regulate people’s appetites without any drugs or invasive medical procedures. This targeted stimulation triggers the brain to modulate gut hormones related to hunger.
Allogeneic hematopoietic stem cell transplantation is a deterministic curative procedure for various hematologic disorders and congenital immunodeficiency. Despite its increased use, the mortality rate for patients undergoing this procedure
Different fates of neural stem/progenitor cells (NSPCs) and their progeny are determined by the gene regulatory network, where a chromatin-remodeling complex affects synergy with other regulators. Here, we review recent research progress in
Acute respiratory distress syndrome (ARDS) is a common and clinically devastating disease that causes respiratory failure. Morbidity and mortality of patients in intensive care units are stubbornly high, and various complications severely a
Mesenchymal stromal/stem cells (MSCs) are currently applied in regenerative medicine and tissue engineering. Numerous clinical studies have indicated that MSCs from different tissue sources can provide therapeutic benefits for patients. MSC
BACKGROUNDThere is no established treatment to impede the progression or restore kidney function in human chronic kidney disease (CKD). AIMTo examine the efficacy of cultured human CD34+ cells with enhanced proliferating potential in kidne
BACKGROUNDFibroblast plays a major role in tendon-bone healing. Exosomes derived from bone marrow mesenchymal stem cells (BMSCs) can activate fibroblasts and promote tendon-bone healing via the contained microRNAs (miRNAs). However, the und
Cancer stem cells (CSCs) are the main cause of tumor growth, invasion, metastasis and recurrence. Recently, CSCs have been extensively studied to identify CSC-specific surface markers as well as signaling pathways that play key roles in CSC
Osteoarthritis (OA) is the most common musculoskeletal disease, and it is a major cause of pain, disability and health burden. Pain is the most common and bothersome presentation of OA, but its treatment is still suboptimal, due to the shor
A century has passed since the Nobel Prize winning discovery of insulin, which still remains the mainstay treatment for type 1 diabetes mellitus (T1DM) to this day. True to the words of its discoverer Sir Frederick Banting, “insulin is no
Cell transplantation therapy has certain limitations including immune rejection and limited cell viability, which seriously hinder the transformation of stem cell-based tissue regeneration into clinical practice. Extracellular vesicles (EVs
Since dental pulp stem cells (DPSCs) were first reported, six types of dental SCs (DSCs) have been isolated and identified. DSCs originating from the craniofacial neural crest exhibit dental-like tissue differentiation potential and neuro-e
Obesity, the global pandemic since industrialization, is the number one lifestyle-related risk factor for premature death, which increases the incidence and mortality of various diseases and conditions, including cancer. In recent years, th
Mayo Clinic ha logrado avances importantes en la biofabricación de productos terapéuticos en etapa inicial. La atención se centra en medicamentos nuevos derivados del cuerpo humano, llamados productos bioterapéuticos, que están dando forma al futuro de la medicina.
قطعت مايو كلينك خطوات كبيرة في مجال التصنيع الحيوي للعلاجات في مراحلها المبكرة. وينصب التركيز في هذا المجال على أدوية جديدة مشتقة من جسم الإنسان، تسمى العلاجات الحيوية، والتي ستشكّل مستقبل الأدوية.
A Mayo Clinic fez avanços significativos na biomanufatura de produtos terapêuticos de estágio inicial. O foco está em novos medicamentos derivados do organismo humano, chamados de produtos bioterapêuticos, que estão definindo o futuro da medicina.
Creating accessible, affordable equipment to democratize research is the foundation of frugal science. Now, with a new five-year grant from the National Institutes of Health (NIH), Bhamla and Standeven will pave the way to bring frugal science to high schools across Georgia.
As part of its “Moon to Mars” initiative, NASA plans to send humans farther into space than ever before.
Scientists demonstrated that human 14-3-3 proteins, that are known for their role in replication of many viruses, bind differentially with more often mutating regulatory part of nucleoprotein (N protein) of coronavirus SARS-CoV-2.
Researcher will discuss the study which involved a sleeping aid known as suvorexant that is already approved by the Food and Drug Administration (FDA) for insomnia, hints at the potential of sleep medications to slow or stop the progression of Alzheimer’s disease.
Scientists have long been intrigued by the remarkable properties of spider silk, which is stronger than steel yet incredibly lightweight and flexible. Now engineers have made a significant breakthrough in the fabrication of synthetic spider silk, paving the way for a new era of sustainable clothing production.
Imagine by only attaching a number of electromyography (EMG) sensors to your legs, your motion in the future several seconds can be predicted. Such a way of predicting motion via muscle states is an alternative to the mainstream visual cue-based motion prediction, which heavily relies on multi-view cameras to construct time-series posture. However, there is still a gap between muscle states and future movements.
An essential pillar of Earth’s ecological system, fungi have long been used to better the lives of humans. While these organisms are still vastly understudied, a new review paper suggests that their unique genomes could be used to make progress in the biotech industry.
The proposed material is chemically similar to mammalian proteins and is non-toxic, therefore contributing to fast adherence and division of human stem cell cultures. This development will help accelerate cell culture growth, which are used in medicine as a replacement for damaged tissue.
Air pollution and its high concentration in cities is one of the problems facing society today, due to its harmful effects on the environment, but also on human health. One of the causes of this pollution is the increase in nitrogen oxide emissions, mainly due to the use of fossil fuels.
A group of researchers at the State University of Campinas (UNICAMP) in Brazil have grown microalgae under controlled conditions in a laboratory in order to use their metabolites, especially lipids, with the prime purpose of producing biofuel.
Scientists in Melbourne have designed a new type of oral capsule that could mean pain-free delivery of insulin and other protein drugs.
University of Pittsburgh researchers developed a novel approach that promoted bone regeneration in mice without implantation of bone tissue or biomaterials.
Hackensack Meridian Health, the state’s largest and most comprehensive health network, is partnering with Etta.io., a Denver-based healthcare technology startup that builds Artificial Intelligence (AI) applications to detect tumors difficult to see with the naked eye, even for specialists.
Today, foldable phones are ubiquitous. Now, using models that predict how well a flexible electronic device will conform to spherical surfaces, University of Wisconsin–Madison and University of Texas at Austin engineers could usher in a new era in which these bendy devices can integrate seamlessly with parts of the human body.
Roots of a traditional medicine plant called the orange climber can fluoresce an ethereal blue hue under ultraviolet (UV) light. And now, researchers in ACS Central Science have identified two coumarin molecules that could be responsible, one of the which could someday be used for medical imaging.
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