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Released: 29-Apr-2022 11:20 AM EDT
New sleep molecule discovered: “It shows just how complex the machinery of sleep is”
University of Copenhagen, Faculty of Health and Medical Sciences

When brain scientist Birgitte Kornum from the Department of Neuroscience recently arrived in Rome for one of the largest sleep conferences in the world, she was completely taken aback.

Released: 29-Apr-2022 11:05 AM EDT
Future Wearable Health Tech Could Measure Gases Released From Skin
Ohio State University

Scientists have taken the first step to creating the next generation of wearable health monitors.

Released: 29-Apr-2022 11:05 AM EDT
Insulin Spray Improved Gait, Cognitive Function in Patients with and Without Type 2 Diabetes, Clinical Trial Shows
Beth Israel Deaconess Medical Center

Scientists have assessed the long-term effects of intranasal insulin on cognition and on gait in people with and without type 2 diabetes mellitus.

Newswise: CDI Scientist Dartois Co-authors Major Update on Global TB fight
Released: 29-Apr-2022 11:05 AM EDT
CDI Scientist Dartois Co-authors Major Update on Global TB fight
Hackensack Meridian Health

“For now, big challenges remain, but change has already come and there is cause for optimism with a healthy dose of realism,” the authors write.

Released: 29-Apr-2022 11:05 AM EDT
High mortality for hospital referred Malawian children with low glucose or blood oxygen levels
Karolinska Institute

A study in rural Malawi underscores the need for better clinical management of severely ill children with very low blood sugar or blood oxygen levels.

Newswise: Study: Unprecedented Increase in Number of Border Wall Falls and Trauma
Released: 29-Apr-2022 11:05 AM EDT
Study: Unprecedented Increase in Number of Border Wall Falls and Trauma
UC San Diego Health

Trauma physicians at UC San Diego Health attribute the rise in injuries to a height increase of the border wall at U.S.-Mexico border.

Released: 29-Apr-2022 11:00 AM EDT
New Studies Show Special Mental Health Risks for Certain Groups of New Doctors
Michigan Medicine - University of Michigan

First-year surgery residents, and first-year medical residents in all fields who are members of sexual minorities such as LGBTQ, are more likely than others to develop depression during the stressful training period.

Newswise: Can computers write product reviews with a human touch?
Released: 29-Apr-2022 10:05 AM EDT
Can computers write product reviews with a human touch?
Dartmouth College

Artificial intelligence systems can be trained to write human-like product reviews that assist consumers, marketers and professional reviewers, according to a study from Dartmouth College, Dartmouth’s Tuck School of Business, and Indiana University.

Released: 29-Apr-2022 10:05 AM EDT
Light-Infused Particles Go the Distance in Organic Semiconductors
Cornell University

Polaritons offer the best of two very different worlds. These hybrid particles combine light and molecules of organic material, making them ideal vessels for energy transfer in organic semiconductors. They are both compatible with modern electronics but also move speedily, thanks to their photonic origins.

Newswise: Fermilab Engineers Develop New Control Electronics for Quantum Computers That Improve Performance, Cut Costs
Released: 29-Apr-2022 10:00 AM EDT
Fermilab Engineers Develop New Control Electronics for Quantum Computers That Improve Performance, Cut Costs
Fermi National Accelerator Laboratory (Fermilab)

Quantum computing experiments now have a new control and readout electronics option that will significantly improve performance while replacing cumbersome and expensive systems. Developed by a team of engineers at Fermilab in collaboration with the University of Chicago, the Quantum Instrumentation Control Kit, or QICK for short, is easily scalable.

Released: 29-Apr-2022 9:55 AM EDT
妙佑医疗国际(Mayo Clinic)研究人员通过CAR-T细胞装载溶瘤病毒治疗实体癌肿瘤
Mayo Clinic

妙佑医疗国际(Mayo Clinic)个体化医学中心的研究人员设计出一种免疫治疗技术,通过将嵌合抗原受体-T细胞疗法,即CAR-T细胞疗法与一种抗癌病毒相结合,更有效地靶向和治疗实体癌肿瘤。

Released: 29-Apr-2022 9:50 AM EDT
باحثو مايو كلينك يقومون بتحميل الخلايا التائية ذات مستقبلات المستضد الخيمرية ذات الفيروس المحلل للورم لعلاج الأورام السرطانية الصلبة
Mayo Clinic

ابتكر باحثون من مركز مايو كلينك للطب الفردي أسلوبًا للعلاج المناعي يجمع بين العلاج بالخلايا التائية ذات مستقبلات المستضد الخيمرية، أو العلاج بخلايا CAR-T، والفيروس قاتل السرطان لاستهداف الأورام السرطانية الصلبة وعلاجها بشكل أكثر فعالية

Released: 29-Apr-2022 9:45 AM EDT
Pesquisadores da Mayo Clinic carregam células CAR-T com vírus oncolítico para tratar tumores sólidos
Mayo Clinic

Pesquisadores do Centro de Medicina Individualizada da Mayo Clinic criaram uma técnica de imunoterapia que combina terapia de células T com receptor de antígeno quimérico, ou terapia celular CAR-T, com um vírus que mata o câncer para direcionar melhor o alvo e tratar com mais eficiência tumores de câncer sólidos.

Released: 29-Apr-2022 5:00 AM EDT
Adipose Mesenchymal Stem Cell-Derived Exosomes Promote Wound Healing Through the WNT/β-catenin Signaling Pathway in Dermal Fibroblasts
Stem Cell Reviews and Reports

… , movement, and morphology of cells, and it is also involved in mediating stem cell pluripotency [20]. β‐Catenin, a subunit of the cadherin … that whether ADMSC-Exos can also promote skin stem cell differentiation through the WNT signaling pathway …

Released: 29-Apr-2022 5:00 AM EDT
In vitro culture of hematopoietic stem cell niche using angiopoietin-1-coupled alginate hydrogel
International Journal of Biological Macromolecules

… stem cell niche. Here, we hypothesized that regulation of cell-cell interactions using a polymeric scaffold as synthetic extracellular matrix (ECM) could be critical in creating a hematopoietic stem cell … and cell-instructive characteristics for stem cell …

Released: 29-Apr-2022 5:00 AM EDT
Low-dose unfractionated heparin prophylaxis is a safe strategy for the prevention of hepatic sinusoidal obstruction syndrome after myeloablative adult allogenic stem cell transplant
Bone Marrow Transplantation

Hepatic sinusoidal obstruction syndrome (SOS) is a serious complication after allogeneic stem cell transplantation (allo-HCT). However, there is no uniform consensus on the optimal strategy for SOS prevention. Ursodeoxycholic acid is the …

Released: 29-Apr-2022 5:00 AM EDT
Optimization of a PDMS-Based Cell Culture Substrate for High-Density Human-Induced Pluripotent Stem Cell Adhesion and Long-Term Differentiation into Cardiomyocytes under a Xeno-Free Condition
ACS Biomaterials Science & Engineering

… In this study, we found that the PDMS substrate coated with a combination of polydopamine (PDA) and laminin-511 E8 fragments (PDA + LME8-coated PDMS) can support human-induced pluripotent stem cell (hiPSC) attachment and growth for …

Released: 29-Apr-2022 5:00 AM EDT
Intrinsic role of chaperone-mediated autophagy in cancer stem cell maintenance
Autophagy

… Its impact in any cancer stem cell (CSC) subtype remained elusive. In a recent study, we characterized the expression of LAMP2A and CMA activity in glioblastoma revealing its enrichment in a glioma stem cell (GSC) subpopulation. LAMP2A …

Released: 29-Apr-2022 5:00 AM EDT
4-hydroxybenzophenone exposure inhibits mouse hippocampal neural stem cell proliferation in vitro by upregulating Cxcl1
Toxicology in Vitro

Benzophenones are widely used in industry and commonly added in many personal care products. However, the neurotoxicity, in particular neurodevelopmental toxicity, of benzophenone family chemicals and metabolites has not been fully elucidated …

Released: 29-Apr-2022 5:00 AM EDT
Human Umbilical Cord Mesenchymal Stem Cell–Based in vitro Model for Neurotoxicity Testing
Current Protocols

… Human neuronal models range from various neuroblastoma cell lines to stem cell–derived systems, including those derived from mesenchymal stem/stromal cells (hMSC). hMSCs exhibit numerous advantages, including the fact that they can be obtained in …



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