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Article ID: 688837

Simmons Cancer Center Researchers Part of Historic CAR-T Breakthrough

UT Southwestern Medical Center

A historic study involving researchers from UT Southwestern’s Harold C. Simmons Comprehensive Cancer Center demonstrates the effectiveness of CAR-T therapy, which uses genetically modified immune cells to treat acute lymphoblastic leukemia in children and young adults.

Released:
1-Feb-2018 3:05 PM EST
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Cancer, Cell Biology, Genetics, NEJM, Local - Texas, Local - Dallas Metro, All Journal News

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  • Embargo expired:
    31-Jan-2018 5:00 PM EST

Article ID: 688502

Catheter Ablation Better Than Pharmacological Atrial Fibrillation Therapies

University of Utah Health

A new study revealed patients receiving radiofrequency catheter ablation compared to traditional drug therapies for atrial fibrillation (AF), a contributing factor to heart failure, had significantly lower hospitalization and mortality rates. The findings are published in the February 1 issue of the New England Journal of Medicine.

Released:
26-Jan-2018 10:00 AM EST
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All Journal News, Cardiovascular Health, Heart Disease, NEJM

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  • Embargo expired:
    31-Jan-2018 5:00 PM EST

Article ID: 688535

T Cell Therapy Shows Persistent Benefits in Young Leukemia Patients

Children's Hospital of Philadelphia

Updated results from a global clinical trial of the CAR T-cell therapy, tisagenlecleucel, a landmark personalized treatment for a high-risk form of acute lymphoblastic leukemia (ALL), reveal that children and young adults continued to show high rates of durable, complete remission of their disease. Most side effects were short-lived and reversible.

Released:
26-Jan-2018 12:20 PM EST
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All Journal News, Blood Disorders, Cancer, Cell Biology, Children's Health, NEJM, Local - Pennsylvania

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  • Embargo expired:
    31-Jan-2018 5:00 PM EST

Article ID: 688711

Landmark International Study: CAR T-Cell Therapy Safe and Effective in Children and Young Adults with Leukemia

Childrens Hospital Los Angeles

Results of the global, multicenter, pivotal phase 2 study that led to the first FDA approval of a gene therapy/cell therapy approach known as CAR T-cell therapy, were published today in the New England Journal of Medicine.

Released:
30-Jan-2018 8:05 PM EST
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All Journal News, Blood Disorders, Cancer, Children's Health, NEJM, Local - California, Local - LA Metro, Genetics

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Article ID: 688461

Drug Discount Program Aimed at Improving Care for Low-Income Patients Generated Gains for Hospitals Without Clear Benefits for the Needy

Harvard Medical School

A 25-year-old drug discount program aimed at boosting resources for hospitals treating low-income patients did not deliver on its promise to enhance care for the needy, according to research from Harvard Medical School and the NYU School of Medicine.

Released:
24-Jan-2018 6:05 PM EST
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All Journal News, Healthcare, Patient Safety, Pharmaceuticals, NEJM, Local - Massachusetts, Local - Boston Metro

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  • Embargo expired:
    24-Jan-2018 5:00 PM EST

Article ID: 688456

Alzheimer's Drug Targeting Soluble Amyloid Falls Short in a Large Clinical Trial

Columbia University Medical Center

A paper published today in the New England Journal of Medicine reports that solanezumab, a monoclonal antibody-based treatment for Alzheimer’s disease developed by Eli Lilly that targets amyloid plaques, did not significantly slow cognitive decline.

Released:
24-Jan-2018 4:55 PM EST
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Alzheimer's and Dementia, Neuro, NEJM, Local - New York, Local - New York Metro, All Journal News

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Article ID: 688285

E-Cigarettes: Harm Reduction or ‘Gateway’ to New Smokers?

Texas A&M University

Smoking is an issue that has been at the heart of public health concerns for decades, with many efforts to restrict tobacco sales, tax cigarettes and sometimes hard-hitting campaigns to get people to quit smoking. But if the tobacco control community has long agreed on the harms of smoking, the place of reducing, rather than eliminating, harm has been hotly contested.

Released:
22-Jan-2018 3:50 PM EST
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Law and Public Policy

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Public Health, Smoking, NEJM, Local - Texas, All Journal News

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    17-Jan-2018 5:00 PM EST

Article ID: 687972

Patients with Blood Cancer Precursor at Risk of Developing Cancer Even After 30 Years

Mayo Clinic

Patients with monoclonal gammopathy of undetermined significance are at risk of progressing to multiple myeloma or a related cancer ─ even after 30 years of stability. These are the findings of a study by Mayo Clinic researchers published in the Wednesday, Jan. 17, issue of the New England Journal of Medicine.

Released:
16-Jan-2018 11:05 AM EST
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  • Embargo expired:
    17-Jan-2018 5:00 PM EST

Article ID: 687984

Multivalent Antibodies Show Effectiveness for HIV Prevention and Promise for Treatment and Cure

University of North Carolina Health Care System

Recent studies testing multivalent combinations of three broadly neutralizing antibodies, or bnAbs, have yielded promising results in animal models of HIV prevention. Two investigators at the University of North Carolina at Chapel Hill describe the potential of bnAbs to inform HIV prevention, treatment and cure strategies in a recent article in the New Journal of Medicine.

Released:
16-Jan-2018 1:30 PM EST
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AIDS and HIV, All Journal News, Infectious Diseases, NEJM

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  • Embargo expired:
    17-Jan-2018 5:00 PM EST

Article ID: 688099

Pacientes Que Tienen Precursor De Cáncer Sanguíneo Corren Riesgo De Desarrollar Cáncer Incluso Después De 30 años

Mayo Clinic

Los pacientes con gammapatía monoclonal de significado incierto corren más riesgo de avanzar hacia mieloma múltiple u otro cáncer afín, incluso después de 30 años de estabilidad.

Released:
17-Jan-2018 5:05 PM EST
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All Journal News, Bone Health, Cancer, Cell Biology, NEJM


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