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Article ID: 696509

Lethal Prostate Cancer Treatment May Benefit from Combination Immunotherapy

Johns Hopkins Medicine

Researchers at the Johns Hopkins Kimmel Cancer Center and the Bloomberg~Kimmel Institute for Cancer Immunotherapy (BKI) released a study investigating the use of combination checkpoint immunotherapy in the treatment of a lethal form of advanced prostate cancer. The study suggested a genetic subset of prostate cancer may benefit from this form of immunotherapy.

Released:
25-Jun-2018 9:00 AM EDT
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    25-Jun-2018 9:00 AM EDT

Article ID: 696245

Researchers Identify Brain Cells Responsible for Removing Damaged Neurons After Injury

The Rockefeller University Press

Researchers at the University of Virginia School of Medicine have discovered that microglia, specialized immune cells in the brain, play a key role in clearing dead material after brain injury. The study, which will be published June 25 in the Journal of Experimental Medicine, reveals that microglia gobble up the remnants of injured neurons, which could prevent the damage from spreading to neighboring neurons and causing more extensive neurodegeneration.

Released:
19-Jun-2018 9:00 AM EDT
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Article ID: 696532

Children with Existing Allergies Should Be Screened for an Emerging, Severe Chronic Food Allergy

Children's Hospital of Philadelphia

Children with known skin, food and respiratory allergies should be screened for an emerging food allergy called eosinophilic esophagitis (EoE), a painful inflammation of the esophagus. Pediatric allergists who analyzed a very large group of children say that EoE is a later component of the “allergic march”-- in which many children successively develop a series of allergies.

Released:
25-Jun-2018 8:00 AM EDT
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Article ID: 696554

Penn Study Reveals New Therapeutic Target for Slowing the Spread of Flu Virus

Perelman School of Medicine at the University of Pennsylvania

Influenza A hijacks host proteins for viral RNA splicing and blocking these interactions caused replication of the virus to slow, which could point to novel strategies for antiviral therapies.

Released:
22-Jun-2018 3:40 PM EDT
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Article ID: 696216

Scientists Discover How Antiviral Gene Works

Albert Einstein College of Medicine

It’s been known for years that humans and other mammals possess an antiviral gene called RSAD2 that prevents a remarkable range of viruses from multiplying. Now, researchers at Albert Einstein College of Medicine, part of Montefiore, have discovered the secret to the gene’s success: The enzyme it codes for generates a compound that stops viruses from replicating. The newly discovered compound, described in today’s online edition of Nature, offers a novel approach for attacking many disease-causing viruses.

Released:
22-Jun-2018 11:30 AM EDT
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    22-Jun-2018 11:00 AM EDT

Article ID: 696332

Overdose Risk Quintuples with Opioid and Benzodiazepine Use

Health Sciences at the University of Pittsburgh

In the first 90 days of concurrent opioid and benzodiazepine use, the risk of opioid-related overdose increases five-fold compared to opioid-only use among Medicare recipients, according to a new study from the University of Pittsburgh School of Pharmacy.

Released:
20-Jun-2018 9:00 AM EDT
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Embargo will expire:
28-Jun-2018 11:00 AM EDT
Released to reporters:
22-Jun-2018 9:05 AM EDT

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Article ID: 696034

Repurposing Promising Cancer Drugs May Lead to a New Approach to Treating TB

Texas Biomedical Research Institute

Promising experimental cancer chemotherapy drugs may help knock out another life-threatening disease: tuberculosis (TB).

Released:
22-Jun-2018 9:00 AM EDT
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Embargo will expire:
28-Jun-2018 9:00 AM EDT
Released to reporters:
22-Jun-2018 9:00 AM EDT

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A reporter's PressPass is required to access this story until the embargo expires on 28-Jun-2018 9:00 AM EDT

Article ID: 696473

Northwestern Researchers Achieve Unprecedented Control of Polymer Grids

Northwestern University

The first examples of covalent organic frameworks (COFs) were discovered in 2005, but quality has been poor and preparation methods uncontrolled. Now a Northwestern University research team is the first to produce high-quality versions of these materials, demonstrate their superior properties and control their growth. The team’s two-step process produces organic polymers with crystalline, two-dimensional structures. The precision of the material’s structure and the empty space its hexagonal pores provide will allow scientists to design new materials with desirable properties.

Released:
21-Jun-2018 2:05 PM EDT
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