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Released: 24-Mar-2022 7:00 AM EDT
TAVR or SAVR? What can we learn from a pooled meta-analysis of reconstructed time to event data?
European Journal of Cardio-Thoracic Surgery

… of death of any cause or stroke, all-cause mortality, stroke and rehospitalization with a focus on … cause or stroke, the analysis of the HR trend over time shows the superiority of TAVR over … Again, the HR trend over time shows a survival …

Released: 24-Mar-2022 7:00 AM EDT
Long-Term Maintenance of Sinus Rhythm Is Associated with Favorable Echocardiographic Remodeling and Improved Clinical Outcomes after Transcatheter Aortic Valve Replacement
Journal of Clinical Medicine

… In contrast, incidence of postprocedural stroke was relatively low in our study (1.8%), and periprocedural AF was not associated with higher risk of stroke. Risk of stroke after TAVR can be affected by various factors, including antithrombotic regimens …

Newswise: The Comprex charger is back
Released: 24-Mar-2022 3:05 AM EDT
The Comprex charger is back
Empa, Swiss Federal Laboratories for Materials Science and Technology

The Comprex (TM) supercharger, like the turbocharger, is a Swiss invention. The Comprex uses pressure waves in direct contact of the exhaust gas with fresh air for supercharging, while a turbocharger couples two flow machines (a turbine and a compressor). Now a brand new design called "Comprex 2.0" showed many advantages in combination with a natural gas engine.

Released: 24-Mar-2022 2:15 AM EDT
Privacy Preservation in Patient Information Exchange Systems Based on Blockchain: System Design Study
Journal of Medical Internet Research

Background: With the increasing sophistication of the medical industry, various advanced medical services such as medical artificial intelligence, telemedicine, and personalized health care services have emerged. The demand for medic...

Released: 23-Mar-2022 4:35 PM EDT
Maternal socialization, not biology, shapes child brain activity
Elsevier

Children of mothers with clinical depression are at three times greater risk to develop depression themselves than are their low-risk peers.

Released: 23-Mar-2022 4:15 PM EDT
Extreme heat harms forest-dwelling bird chicks more than city ones
Frontiers

Forest bird nestlings are significantly smaller and more likely to die as a result of extreme heat compared to their urban counterparts, reports a new study.

Newswise: Study Provides Clues on Why UTIs and Other Bad Infections Persist
Released: 23-Mar-2022 4:10 PM EDT
Study Provides Clues on Why UTIs and Other Bad Infections Persist
University of Utah Health

A new study led by researchers at University of Utah Health details a novel mechanism that infectious bacteria use to quickly adjust to environmental stress. The discovery could help explain why certain types of common infections—such as urinary tract and bloodstream infections like sepsis—are hard to get rid of.

   
18-Mar-2022 4:05 PM EDT
Do Older Adults Using Statins Have Lower Risk of Developing Parkinsonism Later?
American Academy of Neurology (AAN)

Parkinsonism is a term for a group of neurological conditions that cause movement problems including tremors, slowed movement and stiffness, with Parkinson’s disease being one of the better knowns causes. A new study suggests that older people taking statin drugs have a lower chance of developing parkinsonism later compared to people who were not taking statins. The research is published in the March 23, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology. Statins are drugs used to lower cholesterol in the blood and protect against atherosclerosis, a buildup of plaque in the arteries that can lead to hardening of the arteries, heart attack and stroke.

Released: 23-Mar-2022 3:55 PM EDT
IVF children shown to have a better quality of life as adults in new study
Taylor & Francis

Being conceived via assisted reproductive technology (ART), such as IVF, may provide some advantages in quality of life in adulthood, according to the results of a new study.

Newswise: Migrants from south carrying maize were early Maya ancestors
Released: 23-Mar-2022 3:45 PM EDT
Migrants from south carrying maize were early Maya ancestors
University of New Mexico

New research published this week by University of New Mexico archaeologist Keith Prufer shows that a site in Belize was critical in studying the origins of the ancient Maya people and the spread of maize as a staple food.

Newswise: Correcting night blindness in dogs
Released: 23-Mar-2022 3:30 PM EDT
Correcting night blindness in dogs
University of Pennsylvania

People with congenital stationary night blindness (CSNB) are unable to distinguish objects in dim-light conditions. This impairment presents challenges, especially where artificial lighting is unavailable or when driving at night.

Newswise: UCI-led study reveals how TREM2 gene mutation in brain microglia immune cells can increase Alzheimer’s risk
Released: 23-Mar-2022 3:10 PM EDT
UCI-led study reveals how TREM2 gene mutation in brain microglia immune cells can increase Alzheimer’s risk
University of California, Irvine

The molecular processes caused by a TREM2 (Triggering Receptor Expressed on Myeloid Cells 2) gene mutation in the brain’s microglia immune cells can increase the risk of Alzheimer’s disease, according to a recent study led by researchers at the University of California, Irvine. While many immune cell genes have been associated with Alzheimer’s, the odds are increased two to three times by mutations in TREM2. However, the processes by which these mutations change the function of microglia cells have not been identified until now.

Newswise: Stress hormone reduces altruistic behavior in empathetic people
Released: 23-Mar-2022 3:05 PM EDT
Stress hormone reduces altruistic behavior in empathetic people
Society for Neuroscience

The stress hormone cortisol reduces altruistic behavior and alters activity in brain regions linked to social decision making — but only in people who are better at imagining others’ mental states, according to new research published in JNeurosci.

Released: 23-Mar-2022 3:00 PM EDT
Gray Literature in Evaluating Effectiveness in Digital Health and Health and Welfare Technology: A Source Worth Considering
Journal of Medical Internet Research

Background: The need to assess the effectiveness and value of interventions involving digital health and health and welfare technologies is becoming increasingly important due to the rapidly growing development of these technologies ...

Released: 23-Mar-2022 2:45 PM EDT
Digital Assessment Tools Using Animation Features to Quantify Alcohol Consumption: Systematic App Store and Literature Review
Journal of Medical Internet Research

Background: Accurate and user-friendly assessment tools for quantifying alcohol consumption are a prerequisite for effective interventions to reduce alcohol-related harm. Digital assessment tools (DATs) that allow the description of ...

Released: 23-Mar-2022 2:45 PM EDT
Success Factors of Medical Crowdfunding Campaigns: Systematic Review
Journal of Medical Internet Research

Background: Medical crowdfunding provides opportunities for individuals who lack financial resources to access the health services that they need. Despite the popularity of medical crowdfunding, the current understanding of the succe...

Released: 23-Mar-2022 2:45 PM EDT
Review of Mobile Apps for Women With Anxiety in Pregnancy: Maternity Care Professionals’ Guide to Locating and Assessing Anxiety Apps
Journal of Medical Internet Research

Background: Mental health and pregnancy apps are widely available and have the potential to improve health outcomes and enhance women’s experience of pregnancy. Women frequently access digital information throughout their pregnancy...

Released: 23-Mar-2022 2:30 PM EDT
Stratified Impacts of the Infodemic During the COVID-19 Pandemic: Cross-sectional Survey in 6 Asian Jurisdictions
Journal of Medical Internet Research

Background: Although timely and accurate information during the COVID-19 pandemic is essential for containing the disease and reducing mental distress, an infodemic, which refers to an overabundance of information, may trigger unplea...

Released: 23-Mar-2022 2:30 PM EDT
Social Media–Delivered Patient Education to Enhance Self-management and Attitudes of Patients with Type 2 Diabetes During the COVID-19 Pandemic: Randomized Controlled Trial
Journal of Medical Internet Research

Background: The use of mobile health technologies has been necessary to deliver patient education to patients with diabetes during the COVID-19 pandemic. Objective: This open-label randomized controlled trial evaluat...

Released: 23-Mar-2022 2:15 PM EDT
Process and Outcome Evaluations of Smartphone Apps for Bipolar Disorder: Scoping Review
Journal of Medical Internet Research

Background: Mental health apps (MHAs) provide opportunities for accessible, immediate, and innovative approaches to better understand and support the treatment of mental health disorders, especially those with a high burden, such as ...

Released: 23-Mar-2022 2:00 PM EDT
A Question-and-Answer System to Extract Data From Free-Text Oncological Pathology Reports (CancerBERT Network): Development Study
Journal of Medical Internet Research

Background: Information in pathology reports is critical for cancer care. Natural language processing (NLP) systems used to extract information from pathology reports are often narrow in scope or require extensive tuning. Consequentl...

21-Mar-2022 8:05 AM EDT
Novel Therapeutic Strategy Shows Promise Against Pancreatic Cancer
Albert Einstein College of Medicine

Pancreatic cancer is notoriously difficult to cure or even treat. Now, a new strategy devised by scientists at Albert Einstein College of Medicine has succeeded in making pancreatic tumors visible to the immune systems of mice and vulnerable to immune attack, reducing cancer metastases by 87%. The paper describing the findings published online today in Science Translational Medicine.

Newswise:Video Embedded traffic-stops-and-race-police-conduct-may-bend-to-local-biases
VIDEO
Released: 23-Mar-2022 1:55 PM EDT
Traffic Stops and Race: Police Conduct May Bend to Local Biases
Association for Psychological Science

When it comes to police traffic stops, the context in which police officers operate is important. New research covering tens of millions of U.S. traffic stops found that Black drivers were more likely than White drivers to be stopped by police in regions with a more racially biased White population.

Released: 23-Mar-2022 1:25 PM EDT
Pathways: Inclusivity in Dermatology to Increase Number of Black, Latino, and Indigenous Physicians in Dermatology
American Academy of Dermatology

People of color often face unequal access to health care and experience poorer outcomes across the health care landscape. In the field of dermatology, these patients often don’t know where to turn for skin health advice and are 50% less likely than other patients to see a dermatologist for the same conditions.

Released: 23-Mar-2022 1:25 PM EDT
In-Vitro Fertilization Clinics Offering Money-Back Guarantees Achieve Better Outcomes with Less Aggressive Treatments
Rensselaer Polytechnic Institute (RPI)

In-vitro fertilization (IVF) clinics that offer money-back guarantees (MBGs) for their services achieve a higher live-birth success rate with less aggressive treatments than clinics that do not provide money-back guarantees.

Newswise: Chemical Found in Leafy Greens Shown to Slow Growth of COVID-19 and Common Cold Viruses
Released: 23-Mar-2022 12:45 PM EDT
Chemical Found in Leafy Greens Shown to Slow Growth of COVID-19 and Common Cold Viruses
Johns Hopkins Medicine

Researchers at Johns Hopkins Children’s Center report evidence from lab experiments that a chemical derived from a compound found abundantly in broccoli and other cruciferous plants may offer a potentially new and potent weapon against the viruses that cause COVID-19 and the common cold.

Released: 23-Mar-2022 12:30 PM EDT
Study Finds Complex Relationships between Bacteria and Markers of Lower Airway Infection and Inflammation in Cystic Fibrosis
Ann and Robert H. Lurie Children's Hospital of Chicago

The lower airways of patients with cystic fibrosis (CF) have unique biochemical features that correlate with the complex communities of lung bacteria typical of this disease, according to a multicenter study led by researchers from Ann & Robert H. Lurie Children’s Hospital of Chicago. These findings offer insights into the underlying biological mechanisms driving infection and inflammation in the CF lungs, and may help develop novel targeted therapies and more precise diagnostics to improve the care of children with CF.

Newswise: FDA Approved New Immunotherapy Regimen for Patients with Melanoma Based on Johns Hopkins Research
Released: 23-Mar-2022 12:25 PM EDT
FDA Approved New Immunotherapy Regimen for Patients with Melanoma Based on Johns Hopkins Research
Johns Hopkins Medicine

The U.S. Food and Drug Administration has approved a novel therapy for patients with metastatic or inoperable melanoma, an aggressive type of skin cancer. The treatment is developed based on original research conducted at the Johns Hopkins Kimmel Cancer Center.

Released: 23-Mar-2022 12:15 PM EDT
Powerful people feel, express less gratitude
Cornell University

Powerful people in the upper echelons of organizations have plenty to be grateful for, but new Cornell University research indicates that higher-power individuals feel and express less gratitude to their subordinates.

   
Released: 23-Mar-2022 12:05 PM EDT
Neighbourhoods feeling the heat as medium density housing robs suburbs of street and garden trees
University of South Australia

University of South Australia researchers are calling for new national planning policies to mandate the inclusion of trees in any future housing developments and architectural designs.

Released: 23-Mar-2022 12:00 PM EDT
Update on Glycosphingolipids Abundance in Hepatocellular Carcinoma
Preprints

Hepatocellular carcinoma (HCC) is the most frequent type of primary liver cancer. Low numbers of HCC patients being suitable for liver resection or transplantation and multidrug resistance development during pharmacotherapy leads to high death rates for HCC patients.

22-Mar-2022 3:25 PM EDT
Novel therapy could help people with asthma, COPD, cystic fibrosis and cancer-related lung disease
University of Texas MD Anderson Cancer Center

A multicenter research team co-led by The University of Texas MD Anderson Cancer Center developed the first drug to treat the uncontrolled secretion of mucins in the airways, which causes potentially life-threatening symptoms in millions of Americans with common lung diseases.

Newswise: Dense bones allowed Spinosaurus to hunt underwater
22-Mar-2022 2:00 PM EDT
Dense bones allowed Spinosaurus to hunt underwater
University of Portsmouth

Spinosaurus is the largest predatory dinosaur known - over two metres longer than the longest Tyrannosaurus rex - but the way it hunted has been a subject of debate for decades. In a new paper, published today in Nature, a group of palaeontologists have taken a different approach to decipher the lifestyle of long-extinct creatures: examining the density of their bones.

Newswise: Searching for Mach Waves Inside a Perfect Liquid
Released: 23-Mar-2022 11:05 AM EDT
Searching for Mach Waves Inside a Perfect Liquid
Department of Energy, Office of Science

Scientists have created a new way to examine Mach waves in quark-gluon plasma. This plasma has almost no resistance to flow, making it the world’s most perfect fluid. The shape of a Mach wave can offer important information about quark-gluon plasma. Because quark-gluon plasma existed in the early universe a fraction of a second after the Big Bang, understanding its properties helps scientists understand how the universe formed.

22-Mar-2022 6:05 PM EDT
Only 1 in 4 People Needing Treatment Received Medication for Opioid Use Disorder in Past Year
Rutgers University-New Brunswick

Despite strong evidence that medication is the most effective treatment for opioid use disorder (OUD), adolescents and most adults who might benefit from OUD treatment report no medication use, according to a study by researchers at the Rutgers School of Public Health and Columbia University Mailman School of Public Health.

Newswise: Using Marinated Eggs to Demonstrate Diffusion
17-Mar-2022 1:15 PM EDT
Using Marinated Eggs to Demonstrate Diffusion
American Institute of Physics (AIP)

In American Journal of Physics, researchers were inspired by marinated eggs to demonstrate how diffusion works in an easy and quantifiable way. The basis of the recipe is marinating hard boiled eggs in vinegar or brine, which cures the eggs by sufficiently saturating the egg whites via diffusion. In their experiment, the researchers compared penetration levels of red food dye in the whites of peeled hard-boiled eggs at three different temperatures: refrigerator temperature, room temperature, and in a cool convection oven.

Newswise: A Laser-Powered Upgrade to Cancer Treatment
Released: 23-Mar-2022 10:30 AM EDT
A Laser-Powered Upgrade to Cancer Treatment
Lawrence Berkeley National Laboratory

A new research venture pairs cutting-edge particle accelerator science and radiation therapy using laser-generated proton beams.

   
Released: 23-Mar-2022 8:05 AM EDT
Economic Crime Act has loopholes, says leading economic crime expert
University of Portsmouth

A new UK government act designed to target the assets of Russian oligarchs and other money launderers comes with loopholes, according to an economic crime expert from the University of Portsmouth.

Newswise:Video Embedded concert-hall-acoustics-for-non-invasive-ultrasound-brain-treatments
VIDEO
Released: 23-Mar-2022 8:00 AM EDT
Concert hall acoustics for non-invasive ultrasound brain treatments
University of California San Diego

A team led by engineers at the University of California San Diego has developed a device that is a first step to enabling noninvasive, ultrasound-based therapies for the brain. For example, ultrasound waves are currently being used in clinical trials to treat epilepsy.

   
Newswise: Greenhouse study confirms flood-tolerant varieties of soy
Released: 23-Mar-2022 8:00 AM EDT
Greenhouse study confirms flood-tolerant varieties of soy
American Society of Agronomy (ASA), Crop Science Society of America (CSSA), Soil Science Society of America (SSSA)

Researchers use carbon dioxide in a hydroponic system to quickly and accurately determine how soy varieties fare in oxygen-deprived environments

17-Mar-2022 1:00 PM EDT
Lesbian and Bisexual Women at Elevated Risk of Problem Drinking but Lack Appropriate, Effective Treatment Options
Research Society on Alcoholism

Many lesbian and bisexual women lack access to culturally sensitive and effective alcohol and mental health treatments, according to a new study. The findings suggest that sexual minority women (SMW), especially younger women, women of color, and those with low incomes, face multiple barriers to addressing problematic alcohol use. Previous research has shown that SMW experience higher rates of problem drinking and its negative consequences than heterosexual women. This partly reflects the impact of discrimination and its associated stress. Yet SMW appear relatively unlikely to seek help, and when they do, are less satisfied with it, for reasons including a lack of identity-affirming care and provider bias. Better understanding of SMW’s recognition of alcohol problems, motivation to reduce drinking, and treatment experiences — important influences on outcomes — as well as how their alcohol experiences vary by demographic characteristics can potentially help identify women at risk and in

   


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