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Released: 27-Apr-2022 5:00 AM EDT
E3 ligase HUWE1 promotes PDGF D-mediated osteoblastic differentiation of mesenchymal stem cells by effecting polyubiquitination of β-PDGFR
Journal of Biological Chemistry

… Mesenchymal stem cells (MSCs) are adult stem cell populations and exhibit great potential in regenerative medicine and oncology. Platelet-derived growth factors (PDGFs) are well-known to regulate MSC biology through their chemotactic and mitogenic …

Released: 27-Apr-2022 5:00 AM EDT
Leukotrienes promote stem cell self-renewal and chemoresistance in acute myeloid leukemia
Leukemia

Acute myeloid leukemia (AML) is characterized by poor clinical outcomes due to high rates of relapse following standard-of-care induction chemotherapy. While many pathogenic drivers have been described in AML, our understanding of the …

Newswise: Smart Lighting Controls Primed for Data Mining
Released: 27-Apr-2022 12:05 AM EDT
Smart Lighting Controls Primed for Data Mining
Pacific Northwest National Laboratory

The smarter our buildings become, the more data they generate. Lighting controls data, in particular, could prove valuable for facilities managers, manufacturers, and lighting designers. But as valuable as the data are, the buildings industry is still learning how to interpret and leverage the data.

Released: 26-Apr-2022 3:30 PM EDT
How personality and genetics impact link between racial discrimination and problem drinking
Arizona State University (ASU)

A study published in the Journal of Youth and Adolescence shows that the connection of racial discrimination to problem drinking differs based on personality traits. People who tend to act impulsively in response to negative experiences are more likely to report problematic alcohol use that is associated with racism. But, people who enjoy seeking out new experiences are less likely to report problematic alcohol use that is associated with racism. Though this personality trait is thought to be a common risk factor for alcohol use disorder, this study suggests that people with sensation-seeking personalities can better tolerate or cope with difficult situations such as racism.

Released: 26-Apr-2022 3:25 PM EDT
New climate modeling predicts increasing occurrences of flash flooding across most of the U.S.
University of Oklahoma

The latest U.N. report on climate change documented researchers’ efforts that have shown some measures of global warming are now unavoidable, and current research efforts are focusing on mitigation and adaptation strategies.

Newswise: Home sweet home: Pet cats rarely stray far
Released: 26-Apr-2022 3:10 PM EDT
Home sweet home: Pet cats rarely stray far
Norwegian University of Life Sciences

The domestic cat is one of our most popular pets. In Norway alone, 5.4 million people own approximately 770,000 cats.

Newswise: Decoding the Lifecycle of Photogenerated Charges
Released: 26-Apr-2022 3:05 PM EDT
Decoding the Lifecycle of Photogenerated Charges
Department of Energy, Office of Science

New materials will enable novel technologies to turn sunlight into electricity and fuels. Combinations of molecules and tiny nanoparticles make these materials a reality. Scientists have found a way to track electrons along their round trip from the molecules to the nanoparticles and back, helping to find where electrons can travel and where they get stuck, information that is crucial to finding better combinations for innovative materials.

Released: 26-Apr-2022 3:05 PM EDT
MSU research could lead to new Alzheimer’s treatments
Michigan State University

Working with tiny bacteria, Michigan State University researchers led by Lee Kroos have made a discovery that could have big implications for biology. The researchers revealed a new way that nature can inhibit or switch off important proteins known as intramembrane proteases — pronounced “pro tea aces” — which the team reported April 26th in the journal eLife.

Released: 26-Apr-2022 3:00 PM EDT
The Mutual Influence of the World Health Organization (WHO) and Twitter Users During COVID-19: Network Agenda-Setting Analysis
Journal of Medical Internet Research

Background: Little is known about the role of the World Health Organization (WHO) in communicating with the public on social media during a global health emergency. More specifically, there is no study about the relationship between ...

Newswise: Researchers develop a paper-thin loudspeaker
Released: 26-Apr-2022 2:50 PM EDT
Researchers develop a paper-thin loudspeaker
Massachusetts Institute of Technology (MIT)

MIT engineers have developed a paper-thin loudspeaker that can turn any surface into an active audio source.

Newswise: Could the blueprint for life have been generated in asteroids?
Released: 26-Apr-2022 2:45 PM EDT
Could the blueprint for life have been generated in asteroids?
NASA Goddard Space Flight Center

Using new analyses, scientists have just found the last two of the five informational units of DNA and RNA that had yet to be discovered in samples from meteorites.

Released: 26-Apr-2022 2:30 PM EDT
Six in ten people with COVID-19 still have a least one symptom a year later, long Covid study reveals
European Society of Clinical Microbiology and Infectious Diseases

Six in ten people with COVID-19 still have at least one symptom a year later, a new study being presented at this year’s European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Lisbon, Portugal (23-26 April) has found.

Released: 26-Apr-2022 2:00 PM EDT
Challenges in Participant Engagement and Retention Using Mobile Health Apps: Literature Review
Journal of Medical Internet Research

Background: Mobile health (mHealth) apps are revolutionizing the way clinicians and researchers monitor and manage the health of their participants. However, many studies using mHealth apps are hampered by substantial participant dropout or attrition...

Newswise: UNC Landmark Study Paves the Way for Universal Obstetric Ultrasound
Released: 26-Apr-2022 2:00 PM EDT
UNC Landmark Study Paves the Way for Universal Obstetric Ultrasound
University of North Carolina School of Medicine

Establishing accurate gestational age with ultrasound early is essential to delivering high-quality care. Yet, the high cost for equipment and the need for trained sonographers limits its use in low-resource settings. A new study introduces a novel opportunity to democratize obstetric ultrasound.

Newswise: Poor diet associated with increased diabetes risk across all gradients of genetic risk
20-Apr-2022 10:15 AM EDT
Poor diet associated with increased diabetes risk across all gradients of genetic risk
PLOS

A poor diet, irrespective of genetic risk factors, is associated with a 30% increased risk of diabetes

Released: 26-Apr-2022 1:55 PM EDT
Talk therapy may alleviate depression and improve quality of life for people with dementia
University College London

Feelings of anxiety and depression are common in people living with dementia and mild cognitive impairment, but the best way to treat these symptoms is currently unknown, as medicines often used to treat these symptoms may not be effective for people with dementia and may cause side effects.

Released: 26-Apr-2022 1:50 PM EDT
Serious violence peaked after COVID-19 restrictions eased – report
Cardiff University

Serious violence increased by nearly a quarter following the easing of COVID-19 lockdown in England and Wales, according to a new report by Cardiff University.

Newswise: Classifying exoplanet atmospheres opens new field of study
Released: 26-Apr-2022 1:50 PM EDT
Classifying exoplanet atmospheres opens new field of study
National Institutes of Natural Sciences (NINS)

An international team of researchers examined data for 25 exoplanets and found some links among the properties of the atmospheres, including the thermal profiles and chemical abundances in them.

Released: 26-Apr-2022 1:35 PM EDT
Rates of handgun carriage rise among US adolescents, particularly White, rural, and higher income teens, new study finds
Boston College

Handgun carrying increased significantly among rural, White and higher-income adolescents from 2002 to 2019, ominously escalating the risk of firearm-related death or injury for both these youths and others in their social sphere, researchers from Boston College’s Lynch School of Education and Human Development report in the latest edition of the journal Pediatrics.

Released: 26-Apr-2022 1:35 PM EDT
Researchers use muonic x-rays to find elemental makeup of samples without damaging them
Kavli Institute for the Physics and Mathematics of the Universe

By combining technologies originally designed for high-energy particle accelerators and astronomy observations, researchers can now for the first time analyze the elemental makeup of samples without damaging them, which could be useful for researchers working in other fields such as archaeology, reports a new study in Scientific Reports.



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