Researchers at the San Diego Branch of the Ludwig Institute for Cancer Research at UC San Diego report inhibiting activity of a specific protein in glioblastomas boosts their sensitivity to radiation, improving treatment prospects for one of the most common and aggressive forms of brain cancer.
Researchers at the San Diego branch of the Ludwig Institute for Cancer Research at University of California San Diego have identified an entirely new mechanism underlying the development and structure of the nervous system during embryogenesis.
Researchers at the University of Oslo find that when lipids land on a surface they form tiny cell-like containers without external input, and that large organic molecules similar in size to DNA’s building blocks can spontaneously enter these protocells while they grow. Both of these are crucial steps towards forming a functioning cell.
A multi-center study led by researchers at The University of Texas MD Anderson Cancer Center revealed that a liquid biopsy test called Guardant360®, is comparable to standard tissue biopsies in detection of guideline recommended biomarkers in advanced non-small cell lung cancer (NSCLC), has a faster turn-around time, and has the potential to support identification of more patients who can be treated with targeted therapy.
There are two cannabinoid receptors (CB1 and CB2) in the human body that can be targeted to alleviate certain pathological conditions, including chronic pain. While the CB1 receptors are mostly found in the nervous system and are responsible for psychoactive effects, the CB2 receptors are predominantly present in the immune system. Studies indicate that CB2 is a promising target for immunotherapy, as well as treating inflammatory and neuropathic pain, and neurodegenerative diseases. It has also been shown that molecules blocking CB2 can reduce tumor growth.
Synthego, a leading genome engineering innovation company, today announced its inaugural Genome Engineer Innovation Grant. As part of the company's mission to make world-class genome engineering tools accessible to all scientists and bring first-of-its-kind research to fruition, Synthego will offer a variety of grants to research lab awardees totaling $1 million worth of CRISPR Engineered Cells and CRISPRevolution synthetic sgRNA kits.
By sequencing the entire genomes of tumor cells from six people with a rare cancer of the nose and sinus cavity, Johns Hopkins researchers report they unexpectedly found the same genetic changeone in a gene involved in muscle formationin five of the tumors.
Hunter Hines has turned to Instagram to engage audiences in scientific exchange across the world and has come up with the right formula for success. He is encouraging other scientists to follow suit. His Instagram account @microbialecology currently has 55,000 followers and at the end of 2018, his account received more than 1.4 million views in a single week. The authors share their experience and knowledge about using social media in microbiology outreach at a global scale.
A team of biologists has uncovered a mechanism that determines faithful inheritance of short chromosomes during the reproductive process. The discovery elucidates a key aspect of inheritance—deviation from which can lead to infertility, miscarriages, or birth defects such as Down syndrome.
A team led by José Bauermeister, PhD, MPH, Presidential Professor of Nursing and Director of the Program on Sexuality, Technology, & Action Research (PSTAR), at the University of Pennsylvania School of Nursing (Penn Nursing) designed the My Desires & Expectations (myDEx) tool to address cognitive and emotional factors that influence YGBMSM sexual decision-making when seeking partners online.
New preclinical findings from extensive cell and animal studies suggest that cysteamine bitartrate, a drug already used for a rare kidney disease, could benefit patients with some mitochondrial disorders. No proven effective treatments yet exist for these complex conditions with severe energy deficiency
New research explores stem cells in the rotator cuff in hopes of understanding why fatty accumulation happens at the tear site, instead of proper muscle healing.
New research from Washington University in St. Louis shows that when cells divide rapidly, their mitochondria are fused together. In this configuration, the cell is able to more efficiently use oxygen for energy.
Study reveals how genetic background influences trait inheritance laying the grounds for predicting personal risk of disease.
A combination of X-ray crystallography and cryo-electron microscopy assisted in a collaborative effort to obtain the highest-resolution structure of the fungal protein Hsp104, which may serve to hinder the formation of certain degenerative diseases.
UCLA scientists have developed a new method to quickly screen hundreds of drugs in order to identify treatments that can target specific tumors.
Scientists have discovered a defect in immune cells known as “killer T cells” that explains their inability to destroy cancer tumors. The researchers believe that repairing this defect could make the cells much better cancer killers.
Scientists at the microbiology lab led by Javier Campos-Gómez, Ph.D., in Drug Discovery at Southern Research discovered that Pseudomonas aeruginosa, a bacterium responsible for severe, drug-resistant infections in humans, uses a family of fatty acids, known as “oxylipins,” in a cell-to-cell signaling language critical for its virulence.
Biologic age, a DNA-based estimate of a person’s age, is associated with future development of breast cancer, according to scientists at the National Institutes of Health. If a woman’s biologic age was older than her chronologic age, she had a 15 percent increased risk of developing breast cancer.
Several Roswell Park Comprehensive Cancer Center experts were invited to highlight research and best practices during the TCT/Transplantation and Cellular Therapy Meetings now underway in Houston, Texas.
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