Curated News: Cell (journal)

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Leptomeningeal disease is a rare but lethal complication faced by late-stage melanoma patients. It occurs when cancer cells spread to the membranes covering the brain and spinal cord, or the leptomeninges. This condition, which affects 5% to 8% of melanoma patients, often leads to rapid deterioration and is notoriously resistant to therapies. However, a new Moffitt Cancer Center study, published today in Cell Reports Medicine, uncovers the mechanisms that drive this drug resistance, offering new avenues for potential treatments.

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Study finds that mesalamine, a common anti-inflammatory drug, can fight the fungus Candida albicans in the gut, potentially preventing the risk of invasive candidiasis in patients with blood cancers.

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A roundup of the latest medical discoveries and faculty news at Cedars-Sinai.

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University of Illinois Chicago engineers have helped design a new method to make hydrogen gas from water using only solar power and agricultural waste such as manure or husks. The method reduces the energy needed to extract hydrogen from water by 600%, creating new opportunities for sustainable, climate-friendly chemical production.

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Repeated vaccination and infection leads T cells and B cells to build an "immunity wall"

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UC San Diego biologists have provided new insights on a longstanding puzzle in biology: How complex organisms arise from a single fertilized cell. Producing a new “gene atlas” with 4-D imaging, the researchers captured unprecedented insights on how embryonic development unfolds.

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Scientists with Cedars-Sinai Guerin Children’s, the University of California, San Francisco (UCSF), and other institutions have identified the critical first steps in how the digestive system develops.

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Rutgers Health researchers found that long COVID is associated with active inflammatory changes in the nervous system, but the condition is distinct from Alzheimer’s disease and other neurodegenerative disorders.

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Researchers from Johns Hopkins Medicine say they have uncovered insights as to why lupus symptoms and severity present differently in individuals with the autoimmune condition, which affects up to 1.5 million Americans.

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A new study led by University of Michigan Health Rogel Cancer Center researchers identifies novel biomarkers in renal cell carcinomas.

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Researchers have identified a causal genetic variant strongly associated with childhood obesity. The study provides new insight into the importance of the hypothalamus of the brain and its role in common childhood obesity and the target gene may serve as a druggable target for future therapeutic interventions.

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By examining which genes were turned on and off in a mix of cell types from breast cancer biopsies, a team led by UT Southwestern Medical Center researchers developed a tool that can accurately predict which patients with breast cancer will respond to immunotherapies.

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Fungal disease Fusarium head blight (FHB) is on the rise due to increasingly humid conditions induced by climate change during the wheat growing season, but a fundamental discovery by University of Adelaide researchers could help reduce its economic harm.

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Scientists from the University of California San Diego discovered a novel signaling pathway in liver cells, leading to a treatment for fibrosis.

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Conditions such as diabetes, heart attack and vascular diseases commonly diagnosed in people with spinal cord injuries can be traced to abnormal post-injury neuronal activity that causes abdominal fat tissue compounds to leak and pool in the liver and other organs, a new animal study has found.

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Using state-of-the-art microscopy techniques developed on campus, researchers at UC San Diego School of Medicine have shed new light on the underlying mechanisms driving Alzheimer’s disease.

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A new study offers a first look into the complex molecular changes that occur in brain cells with Lewy bodies, which are key pathological hallmarks of Parkinson’s disease and some dementias.

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The Martinot Lab at Cummings School of Veterinary Medicine at Tufts University, where faculty and students have been researching the mpox virus in endometrial tissues to raise awareness of the potential increased risk of mpox virus for women.